Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Hemophagocytic Lymphohistiocytosis Secondary to Hodgkin Lymphoma with Isolated Bone Marrow Involvement in a Newly Diagnosed HIV Patient

Version 1 : Received: 13 June 2023 / Approved: 13 June 2023 / Online: 13 June 2023 (14:33:46 CEST)

A peer-reviewed article of this Preprint also exists.

Lopez-Garcia, A.; Solan, L.; Alvarez, B.; Caballero, J.C.; Cornago, J.; Pardo, L.; Diaz de la Pinta, F.J.; Cordoba, R.; Rodriguez-Pinilla, M. Hemophagocytic Lymphohistiocytosis Secondary to Hodgkin’s Lymphoma with Isolated Bone Marrow Involvement in a Newly Diagnosed HIV Patient. Medicina 2023, 59, 1274. Lopez-Garcia, A.; Solan, L.; Alvarez, B.; Caballero, J.C.; Cornago, J.; Pardo, L.; Diaz de la Pinta, F.J.; Cordoba, R.; Rodriguez-Pinilla, M. Hemophagocytic Lymphohistiocytosis Secondary to Hodgkin’s Lymphoma with Isolated Bone Marrow Involvement in a Newly Diagnosed HIV Patient. Medicina 2023, 59, 1274.

Abstract

HIV infection is well-known to be associated with the development of Hodgkin's lymphoma (HL) with extranodal involvement being exclusive bone marrow involvement is less common. Co-infection by other viruses such as the esptein Baar virus (EBV) increases the incidence of a frequent complication denominated hemophagocytic lymphohistocytosis (HLH). We present the case of a 50-year-old patient with the above clinical spectrum who develops several serious complications during treatment.

Keywords

Lymphoma; HL; HIV; EBV; HLH

Subject

Medicine and Pharmacology, Hematology

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