Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Perforating Gout: Expanding the Differential for Transepidermal Elimination

Version 1 : Received: 25 May 2023 / Approved: 26 May 2023 / Online: 26 May 2023 (09:36:26 CEST)

A peer-reviewed article of this Preprint also exists.

Bohdanowicz, M.; Bradshaw, S.H. Perforating Gout: Expanding the Differential for Transepidermal Elimination. Dermatopathology 2023, 10, 207-218. Bohdanowicz, M.; Bradshaw, S.H. Perforating Gout: Expanding the Differential for Transepidermal Elimination. Dermatopathology 2023, 10, 207-218.

Abstract

Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is important to keep a broad differential. We present a case of perforating tophaceous gout, which underscores the need for a thoughtful approach to perforating disorders. An updated review of recent literature is also presented.

Keywords

Gout; Tophus; Perforating Dermatosis; Transepidermal Elimination; Pseudoepitheliomatous Hyperplasia; Granulomatous Dermatitis

Subject

Medicine and Pharmacology, Pathology and Pathobiology

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