Version 1
: Received: 22 February 2023 / Approved: 24 February 2023 / Online: 24 February 2023 (09:31:14 CET)
How to cite:
Abrams, B.; Delannoy, P.; Johnson, R. Obstructive Sleep Apnea as a Cause of Gout. Preprints2023, 2023020425. https://doi.org/10.20944/preprints202302.0425.v1
Abrams, B.; Delannoy, P.; Johnson, R. Obstructive Sleep Apnea as a Cause of Gout. Preprints 2023, 2023020425. https://doi.org/10.20944/preprints202302.0425.v1
Abrams, B.; Delannoy, P.; Johnson, R. Obstructive Sleep Apnea as a Cause of Gout. Preprints2023, 2023020425. https://doi.org/10.20944/preprints202302.0425.v1
APA Style
Abrams, B., Delannoy, P., & Johnson, R. (2023). Obstructive Sleep Apnea as a Cause of Gout. Preprints. https://doi.org/10.20944/preprints202302.0425.v1
Chicago/Turabian Style
Abrams, B., Peter Delannoy and Richard Johnson. 2023 "Obstructive Sleep Apnea as a Cause of Gout" Preprints. https://doi.org/10.20944/preprints202302.0425.v1
Abstract
Gout is not only associated with obstructive sleep apnea (OSA), but the intermittent episodes of hypoxia that occur with OSA may also have a role in causing gout. Epidemiological studies have documented a higher incidence and prevalence of gout in individuals diagnosed with OSA than in individuals never diagnosed with OSA. The pathophysiology of OSA’s chronic episodes of hypoxia leading to hyperuricemia and gout involves boththe overproduction and underexcretion of uric acid. Treating OSA may be an additional way to control gout and its life-threatening comorbidities. Clinicians are urged to evaluate their patients with hyperuricemia/gout for OSA as it may lead to alternative ways to control gout with superior outcomes that simply pharmacologic treatment alone.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received:
28 February 2023
Commenter:
Richard J Johnson MD
The commenter has declared there is no conflict of interests.
Comment:
Thank you for your comment. A lot of people do not know too much about the connection, so we thought it might be valuable to discuss it. Thank you for your interest
Commenter:
The commenter has declared there is no conflict of interests.
Commenter: Richard J Johnson MD
The commenter has declared there is no conflict of interests.