PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database
Version 1
: Received: 28 October 2022 / Approved: 1 November 2022 / Online: 1 November 2022 (04:46:18 CET)
How to cite:
Sakamoto, D.; Hamaguchi, T.; Murata, K.; Ito, H.; Nakayama, Y.; Abo, M. Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database. Preprints2022, 2022110018. https://doi.org/10.20944/preprints202211.0018.v1
Sakamoto, D.; Hamaguchi, T.; Murata, K.; Ito, H.; Nakayama, Y.; Abo, M. Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database. Preprints 2022, 2022110018. https://doi.org/10.20944/preprints202211.0018.v1
Sakamoto, D.; Hamaguchi, T.; Murata, K.; Ito, H.; Nakayama, Y.; Abo, M. Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database. Preprints2022, 2022110018. https://doi.org/10.20944/preprints202211.0018.v1
APA Style
Sakamoto, D., Hamaguchi, T., Murata, K., Ito, H., Nakayama, Y., & Abo, M. (2022). Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database. Preprints. https://doi.org/10.20944/preprints202211.0018.v1
Chicago/Turabian Style
Sakamoto, D., Yasuhide Nakayama and Masahiro Abo. 2022 "Restoring Upper Limb Function by Combined Repetitive Transcranial Magnetic Stimulation and Occupational Therapy in Patients with Chronic Stroke: A Stratified Analysis Factoring the Severity of Motor Paralysis using a Multicenter Cohort Study Database" Preprints. https://doi.org/10.20944/preprints202211.0018.v1
Abstract
Repetitive transcranial magnetic stimulation (rTMS) with intensive occupational therapy improves upper limb motor paralysis and activities of daily living after stroke; however, amount of improvement according to paralysis severity remains unverified. Target activities for daily living using patients’ upper limb functions can be established by predicting the amount of change after treatment for each severity level of upper limb motor paralysis and further aid practice planning. This study estimated post-treatment score changes for each severity level of motor paralysis (no, poor, limited, notable, and full) stratified according to Action Research Arm Test (ARAT) scores before combined rTMS and intensive occupational therapy. Severity of motor paralysis was the fixed factor for analysis of covariance, delta (post-pre) of the scores was the dependent variable. Ordinal logistic regression analysis was used to compare changes in ARAT subscores in patients, divided according to paralysis severity before treatment. A multicenter retrospective cohort dataset analyzed 907 patients with stroke hemiplegia. Largest treatment-related changes in scores were observed in the Limited recovery group for upper limb motor paralysis and Full recovery group for quality-of-life activities using paralyzed upper limb. These results will help predict treatment effects and determine exercises and goal movements for occupational therapy after rTMS.
Keywords
stroke; occupational therapy; activities of daily living; goal setting; transcranial magnetic stimulation: upper extremity; motor paralysis
Subject
Medicine and Pharmacology, Orthopedics and Sports Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
