Guardiola, M.; Dghoughi, W.; Sont, R.; Garrido, A.; Marcoval, S.; Neira, L.M.; Belda, I.; Fernández-Esparrach, G. MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models. Sensors2022, 22, 4902.
Guardiola, M.; Dghoughi, W.; Sont, R.; Garrido, A.; Marcoval, S.; Neira, L.M.; Belda, I.; Fernández-Esparrach, G. MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models. Sensors 2022, 22, 4902.
Guardiola, M.; Dghoughi, W.; Sont, R.; Garrido, A.; Marcoval, S.; Neira, L.M.; Belda, I.; Fernández-Esparrach, G. MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models. Sensors2022, 22, 4902.
Guardiola, M.; Dghoughi, W.; Sont, R.; Garrido, A.; Marcoval, S.; Neira, L.M.; Belda, I.; Fernández-Esparrach, G. MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models. Sensors 2022, 22, 4902.
Abstract
This study assesses the efficacy of a microwave colonoscopy algorithm to detect colorectal cancer precursors or polyps in an ex-vivo human colon model. The algorithm works with a device composed of a cylindrical ring-shaped switchable antenna array, which can be attached to the tip of a conventional colonoscope as an accessory. The accessory is connected to an external processing unit that generates an acoustic signal when a polyp is detected. Nowadays, 22% of polyps go undetected with conventional colonoscopy and the risk of cancer after a negative colonoscopy can be up to 7.9%. Fifteen ex-vivo freshly excised human colons with cancer (n=12) or polyps (n=3) were examined with the microwave-assisted colonoscopy system simulating a real colonoscopy exploration. Successive measurements of the colon were taken with the microwave-based colonoscopy device and processed with a microwave imaging algorithm. After the experiment, the dielectric properties of the specimens were measured with a coaxial probe and finally the samples underwent a pathology analysis. The results show that all the neoplasms were detected with a sensitivity of 100% and specificity of 87.4%.
Keywords
endoscopes; medical diagnostic imaging; microwave antenna arrays; microwave imaging; colorectal cancer
Subject
Medicine and Pharmacology, Other
Copyright:
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