Working Paper Review Version 1 This version is not peer-reviewed

Human Bartonellosis: An Underappreciated Public Health Problem?

Version 1 : Received: 24 March 2019 / Approved: 25 March 2019 / Online: 25 March 2019 (11:14:24 CET)

A peer-reviewed article of this Preprint also exists.

Cheslock, M.A.; Embers, M.E. Human Bartonellosis: An Underappreciated Public Health Problem? Trop. Med. Infect. Dis. 2019, 4, 69. Cheslock, M.A.; Embers, M.E. Human Bartonellosis: An Underappreciated Public Health Problem? Trop. Med. Infect. Dis. 2019, 4, 69.

Abstract

Bartonella spp. bacteria can be found around the globe and are the causative agents of multiple human diseases. The most well-known infection is called cat-scratch disease, which causes mild lymphadenopathy and fever. As our knowledge of these bacteria grows, new presentations of disease have been recognized with serious manifestations. Not only has more severe disease been associated with these bacteria, but Bartonella species have also been discovered in a wide range of mammals and the pathogens’ DNA can be found in multiple vectors. This review will focus on some common mammalian reservoirs as well as the suspected vectors in relation to disease transmission and prevalence. Understanding the complex interactions between these bacteria, their vectors, and reservoirs as well as the breadth of infection by Bartonella around the world will help toassess the impact of Bartonellosis on public health.

Keywords

Bartonella, vector, bartonellosis, ticks, fleas, domestic animals, human

Subject

Biology and Life Sciences, Immunology and Microbiology

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