Anastasiadou, E.; Faggioni, A.; Trivedi, P.; Slack, F.J. The Nefarious Nexus of Noncoding RNAs in Cancer. Preprints2018, 2018030187. https://doi.org/10.20944/preprints201803.0187.v1
APA Style
Anastasiadou, E., Faggioni, A., Trivedi, P., & Slack, F.J. (2018). The Nefarious Nexus of Noncoding RNAs in Cancer. Preprints. https://doi.org/10.20944/preprints201803.0187.v1
Chicago/Turabian Style
Anastasiadou, E., Pankaj Trivedi and Frank J. Slack. 2018 "The Nefarious Nexus of Noncoding RNAs in Cancer" Preprints. https://doi.org/10.20944/preprints201803.0187.v1
Abstract
The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts. Many ncRNAs interact with each other and are part of networks that influence the cell transcriptome and proteome and consequently the outcome of biological processes. The regulatory circuits controlled by ncRNAs have become increasingly more relevant in cancer. Further understanding of these complex network interactions and how ncRNAs are regulated, is paving the way for the identification of better therapeutic strategies in cancer.
Keywords
noncoding RNA; miRNA; lncRNA; circRNA; ncRNA network in cancer; cancer biomarkers; RNA aided cancer therapy
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
