Version 1
: Received: 2 November 2016 / Approved: 14 November 2016 / Online: 14 November 2016 (07:14:00 CET)
How to cite:
Jawad, A.H.; Al-Qaisi, Z.H.; Ibrahim, A.E.; Hallab, Z.S.; Graisa, A.; Al-Amiery, A.; Yousif, E. Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus. Preprints2016, 2016110071. https://doi.org/10.20944/preprints201611.0071.v1
Jawad, A.H.; Al-Qaisi, Z.H.; Ibrahim, A.E.; Hallab, Z.S.; Graisa, A.; Al-Amiery, A.; Yousif, E. Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus. Preprints 2016, 2016110071. https://doi.org/10.20944/preprints201611.0071.v1
Jawad, A.H.; Al-Qaisi, Z.H.; Ibrahim, A.E.; Hallab, Z.S.; Graisa, A.; Al-Amiery, A.; Yousif, E. Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus. Preprints2016, 2016110071. https://doi.org/10.20944/preprints201611.0071.v1
APA Style
Jawad, A.H., Al-Qaisi, Z.H., Ibrahim, A.E., Hallab, Z.S., Graisa, A., Al-Amiery, A., & Yousif, E. (2016). Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus. Preprints. https://doi.org/10.20944/preprints201611.0071.v1
Chicago/Turabian Style
Jawad, A.H., Ahmed Al-Amiery and Emad Yousif. 2016 "Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus" Preprints. https://doi.org/10.20944/preprints201611.0071.v1
Abstract
Diabetes mellitus (DM) has been defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy: (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies (Group3). In the study lipid profile level were quantitatively determine by enzymatic methods, in addition to that fasting plasma glucose (FPG), Glycated hemoglobin (HbA1c%) and body mass index (BMI) were identified in the patients. There is significant increase in the level of lipid profile in patients group. Metformin alone produce a non-significant favorable effect on all lipids profile parameters while metformin plus glibenclamide showed a significant reduction in TC and LDL-C.
Keywords
diabetes mellitus; metformin; glibenclamide and lipid profile
Subject
Chemistry and Materials Science, Medicinal Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
