Preprint Review Version 1 NOT YET PEER-REVIEWED

Existing Biosensing Platforms for the Nucleotide Markers Detection

  1. SB RAS, Institute of Chemical Biology and Fundamental Medicine, 630090 Novosibirsk, Russia
  2. SB RAS, A.V. Rzhanov Institute of Semiconductor Physics, 630090 Novosibirsk, Russia
  3. MBU-Technology, Llc., 630090 Novosibirsk, Russia
Version 1 : Received: 9 November 2016 / Approved: 9 November 2016 / Online: 9 November 2016 (10:28:58 CET)

How to cite: Dmitrienko, E.; Pyshnaya, I.; Dultsev, F.; Tronin, A.; Pyshnyi, D. Existing Biosensing Platforms for the Nucleotide Markers Detection. Preprints 2016, 2016110055 (doi: 10.20944/preprints201611.0055.v1). Dmitrienko, E.; Pyshnaya, I.; Dultsev, F.; Tronin, A.; Pyshnyi, D. Existing Biosensing Platforms for the Nucleotide Markers Detection. Preprints 2016, 2016110055 (doi: 10.20944/preprints201611.0055.v1).

Abstract

In review, the operating principles of the most common bio sensing devices, detection methods and the identification sensitivity of analyzed molecules were shown. The central focus was done on hybridization analysis of nucleic acids (NA), which are considered to be one of the most important analytes in terms of diagnostic point of view. Constructions enabling to transfer the fact of formation of nucleotide probe/target complex in to detectable signal by optical, electrochemical or micromechanical (piezoelectric) sensors were presented in this review.

Subject Areas

hybridization analysis; nucleic acids; optical biosensors; electrochemical biosensors; micromechanical (piezoelectric) sensors

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