Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Existing Biosensing Platforms for the Nucleotide Markers Detection

Version 1 : Received: 9 November 2016 / Approved: 9 November 2016 / Online: 9 November 2016 (10:28:58 CET)

How to cite: Dmitrienko, E.; Pyshnaya, I.; Dultsev, F.; Tronin, A.; Pyshnyi, D. Existing Biosensing Platforms for the Nucleotide Markers Detection. Preprints 2016, 2016110055. https://doi.org/10.20944/preprints201611.0055.v1 Dmitrienko, E.; Pyshnaya, I.; Dultsev, F.; Tronin, A.; Pyshnyi, D. Existing Biosensing Platforms for the Nucleotide Markers Detection. Preprints 2016, 2016110055. https://doi.org/10.20944/preprints201611.0055.v1

Abstract

In review, the operating principles of the most common bio sensing devices, detection methods and the identification sensitivity of analyzed molecules were shown. The central focus was done on hybridization analysis of nucleic acids (NA), which are considered to be one of the most important analytes in terms of diagnostic point of view. Constructions enabling to transfer the fact of formation of nucleotide probe/target complex in to detectable signal by optical, electrochemical or micromechanical (piezoelectric) sensors were presented in this review.

Keywords

hybridization analysis; nucleic acids; optical biosensors; electrochemical biosensors; micromechanical (piezoelectric) sensors

Subject

Biology and Life Sciences, Biology and Biotechnology

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