Version 1
: Received: 30 October 2016 / Approved: 31 October 2016 / Online: 31 October 2016 (08:35:41 CET)
How to cite:
Jawad, A.H.; Ibrahim, A.E.; Alsayed, R.; Hallab, Z.S.; Al-Qaisi, Z.; Al-Amery, A.; Yousif, E. Study the Impact of Glucose-6-phosphatase Activity in Type 2 Diabetic Patients and Non Diabetic Counterparts. Preprints2016, 2016100137. https://doi.org/10.20944/preprints201610.0137.v1
Jawad, A.H.; Ibrahim, A.E.; Alsayed, R.; Hallab, Z.S.; Al-Qaisi, Z.; Al-Amery, A.; Yousif, E. Study the Impact of Glucose-6-phosphatase Activity in Type 2 Diabetic Patients and Non Diabetic Counterparts. Preprints 2016, 2016100137. https://doi.org/10.20944/preprints201610.0137.v1
Jawad, A.H.; Ibrahim, A.E.; Alsayed, R.; Hallab, Z.S.; Al-Qaisi, Z.; Al-Amery, A.; Yousif, E. Study the Impact of Glucose-6-phosphatase Activity in Type 2 Diabetic Patients and Non Diabetic Counterparts. Preprints2016, 2016100137. https://doi.org/10.20944/preprints201610.0137.v1
APA Style
Jawad, A.H., Ibrahim, A.E., Alsayed, R., Hallab, Z.S., Al-Qaisi, Z., Al-Amery, A., & Yousif, E. (2016). Study the Impact of Glucose-6-phosphatase Activity in Type 2 Diabetic Patients and Non Diabetic Counterparts<em></em>. Preprints. https://doi.org/10.20944/preprints201610.0137.v1
Chicago/Turabian Style
Jawad, A.H., Ahmed Al-Amery and Emad Yousif. 2016 "Study the Impact of Glucose-6-phosphatase Activity in Type 2 Diabetic Patients and Non Diabetic Counterparts<em></em>" Preprints. https://doi.org/10.20944/preprints201610.0137.v1
Abstract
Glucose-6-phosphatase (G6Pase), an enzyme found mostly in the kidneys and the liver, acting significant role of supplying glucose through starvation. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy : (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies( Group3). The study found that G-6-Pase activity is increased, thereby leading to an increase in endogenous glucose production (EGP) in patients with type 2 diabetes and, therefore FPG will increase. The result found that increasing G-6-Pase activity will increase the concentration of glucose in the blood and that will increase the long-term glycemic control (HbA1c%).
Chemistry and Materials Science, Medicinal Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Commenter: omr
The commenter has declared there is no conflict of interests.