Preprint Review Version 1 NOT YET PEER-REVIEWED

Intestinal Organoids—Current and Future Applications

  1. Universidade Federal Rural da Amazônia, Postdoctoral Fellowship Cnpq, Belém 66077-830, Brazil
  2. Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, Utrecht 3584 CM, The Netherlands
Version 1 : Received: 8 August 2016 / Approved: 9 August 2016 / Online: 9 August 2016 (11:38:04 CEST)

A peer-reviewed article of this Preprint also exists.

Meneses, A.M.C.; Schneeberger, K.; Kruitwagen, H.S.; Penning, L.C.; van Steenbeek, F.G.; Burgener, I.A.; Spee, B. Intestinal Organoids—Current and Future Applications. Vet. Sci. 2016, 3, 31. Meneses, A.M.C.; Schneeberger, K.; Kruitwagen, H.S.; Penning, L.C.; van Steenbeek, F.G.; Burgener, I.A.; Spee, B. Intestinal Organoids—Current and Future Applications. Vet. Sci. 2016, 3, 31.

Journal reference: Vet. Sci. 2016, 3, 31
DOI: 10.3390/vetsci3040031

Abstract

Recent technical advances in the stem cell field have enabled the in vitro generation of complex structures resembling whole organs termed organoids. Most of these approaches employ culture systems that allow stem cell-derived or tissue progenitor cells to self-organize into three-dimensional (3D)-structures. Since organoids can be grown from various species, organs and from patient-derived induced pluripotent stem cells, they create significant prospects for modelling development and diseases, for toxicology and drug discovery studies, and in the field of regenerative medicine. Here, we report on intestinal stem cells, organoid culture, organoid disease modeling, transplantation, current and future uses of this exciting new insight model to veterinary medicine field.

Subject Areas

intestinal organoids; dog; practical applications

Readers' Comments and Ratings (0)

Discuss and rate this article
Views 182
Downloads 298
Comments 0
Metrics 0
Discuss and rate this article

×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.