Preprint Review Version 1 NOT YET PEER-REVIEWED

Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering

  1. Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.za della Scienza 2, 20126 Milano, Italy
Version 1 : Received: 3 August 2016 / Approved: 4 August 2016 / Online: 4 August 2016 (11:00:19 CEST)

A peer-reviewed article of this Preprint also exists.

Sgambato, A.; Cipolla, L.; Russo, L. Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering. Gels 2016, 2, 28. Sgambato, A.; Cipolla, L.; Russo, L. Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering. Gels 2016, 2, 28.

Journal reference: Gels 2016, 2, 28
DOI: 10.3390/gels2040028

Abstract

Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customized biomaterials able to mimic ECM functionalities represent one of the major strategy to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review new strategies and future perspectives of such synthetic cell microenvironment will be highlighted.

Subject Areas

hydrogels; tissue engineering; bioconjugation

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