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Preprint REVIEW | doi:10.20944/preprints202403.0881.v1

Concerns regarding Transfusions of Blood Products Derived from Genetic Vaccine Recipients and Proposals for Specific Measures

Jun Ueda, Hideyuki Motohashi, Yuriko Hirai, Kenji Yamamoto, Yasufumi Murakami, Masanori Fukushima, Akinori Fujisawa

Subject: Medicine And Pharmacology, Transplantation Keywords: COVID-19 vaccine; genetic vaccine; blood product; blood transfusion; spike protein; post-vaccination syndrome; harm–benefit assessment; prion; spikeopathy; inspection standard; diagnostic criteria

Online: 15 March 2024 (08:54:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.1267.v1

Inadvertent Exposure to Pharmacologically Designed Lipid Nanoparticles Via Bodily Fluids: Biologic Plausibility and Potential Consequences

Matthew Halma, Jessica Rose, Peter McCullough

Subject: Medicine And Pharmacology, Transplantation Keywords: Covid-19 vaccination; mRNA vaccine; lipid nanoparticles; blood transfusion; breastfeeding exposure; pharmacovigilance

Online: 22 February 2024 (04:00:44 CET)

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Exposure to vaccine lipid nanoparticles, mRNA, adenoviral DNA, and or Spike protein from one of the approved Covid-19 vaccines, or through secondary exposure, as through blood transfusion, is a potential source of harm. Blood reactions are an acknowledged side-effect of Covid-19 vaccination, not limited to hemolysis, paroxysmal nocturnal hemoglobinuria, chronic cold agglutinin disease, immune thrombocytopenia, haemophagocytosis, hemophagocytic lymphohistiocytosis, and many other blood related conditions. The observation of adverse events has motivated investigation into the cardiovascular mechanisms of harm by Covid-19 vaccines, and the biodistribution of vaccine contents. Biodistribution may not be limited to the body of the vaccine recipient, as a growing body of evidence demonstrates the possibility of secondary exposure to vaccine particles. These can be via bodily fluids and include the following routes of exposure: blood transfusion, organ transplantation, breastfeeding, and possibly other means. As covid-19 vaccines are associated with an increased risk of stroke, the persistence of vaccine artifacts in the blood presents a possible threat to a recipient of a blood donation from a vaccinated donor who suffered from vaccine induced thrombosis or thrombocytopenia. (VITT) We assess the feasibility and significance of these risks through an overview of the case report literature of blood disorders in vaccinated individuals, pharmacovigilance reports from the US Vaccine Adverse Events Reporting System (VAERS) and a meta-analysis of the available literature on organ transplants from vaccinated organ donors. Our analysis establishes biological mechanistic plausibility, a coherent safety signal in pharmacovigilance databases for secondary vaccine contents exposure (for the cases of blood transfusion and breastfeeding) and also an elevated level of adverse events in organ transplants from VITT-deceased donors, echoing increases in organ transplantation related complications seen in national statistics for some countries. Secondary exposure to vaccine artifacts is a potential explanation for some of the cases put forth, and requires a deeper investigation.

Preprint ARTICLE | doi:10.20944/preprints202309.1894.v1

Personality Changes Associated with Organ Transplants

Brian Carter, Laveeen Khoshnaw, Megan Simmons, Lisa Hines, Brandon Wolfe, Mitchell Liester

Subject: Medicine And Pharmacology, Transplantation Keywords: Personality change; organ transplant; heart transplant; temperament; emotions; preferences

Online: 27 September 2023 (11:08:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints201802.0101.v2

Spleen, as an Optimal Site for Islet Transplantation and a Source of Mesenchymal Stem Cells

Naoaki Sakata, Gumpei Yoshimatsu, Shohta Kodama

Subject: Medicine And Pharmacology, Transplantation Keywords: spleen; islet transplantation; transplant site; immunity; tolerance; regeneration; diabetes mellitus; mesenchymal stem cell; Sjogren’s syndrome; HOX

Online: 2 April 2018 (11:05:40 CEST)

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Working Paper REVIEW

Therapeutic Effect of Mesenchymal Stem Cell on Organ Ischemia-Reperfusion Injury

Joan Oliva

Subject: Medicine And Pharmacology, Transplantation Keywords: ischemia-reperfusion injury; mesenchymal stem cells; treatment

Online: 11 June 2019 (04:28:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0098.v1

Impact of COVID-19 Infection on Children and Adolescents after Liver Transplantation in a Latin American Reference Center.

ALINE FALLEIROS DE FREITAS, RENATA PEREIRA SUSTOVICH PUGLIESE, FLAVIA FEIER, IRENE KAZUE MIURA, VERA LUCIA BAGGIO DANESI, ELIENE NOVAIS OLIVEIRA, ADRIANA PORTA HIRSCHFELD, CRISTIAN BARBIERI BORGES, JULIANA VIEIRA LOBATO, GILDA PORTA, JOAO SEDA NETO, EDUARDO ANTUNES FONSECA

Subject: Medicine And Pharmacology, Transplantation Keywords: COVID-19; pediatric liver transplantation; immunosuppression; living donor liver transplantation

Online: 9 May 2022 (03:59:57 CEST)

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Working Paper CASE REPORT

Asymmetric Bone Marrow Involvement in Patients with Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation：Two Case Reports and Literature Review

Wei Shi, Xiaotian Xia, Yingying Wu, Junxia Yao, Wanxin Chen, Xuan Lu, Liang Tang, Linghui Xia, Yong You, Yu Hu

Subject: Medicine And Pharmacology, Transplantation Keywords: asymmetric； blasts；acute leukemia； allogeneic hematopoietic stem cell transplantation； case report

Online: 7 May 2020 (10:53:42 CEST)

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Background: After allogeneic hematopoietic stem cell transplantation (allo-HSCT), acute leukemia relapse is common, and asymmetric bone marrow recurrence hasn’t been reported. Because the anatomical distribution of acute leukemia clones in the bone marrow after allo-HSCT is presumed to be diffuse, bone marrow aspirations are performed in single site. Case presentation: We identified two acute leukemia patients, whose leukemic burden in bilateral bone marrow specimens differed significantly. The first case was a 20-year-old man who was diagnosed with acute myelomonocytic leukemia and received haploidentical allo-HSCT. He had been in complete remission for two years and off immunosuppressive medications for a year, with normal peripheral blood count. Routine bone marrow biopsy of his left posterior iliac bone marrow showed 52% leukemia blasts, while the right side had 0% blasts ten days later. Due to the discordant results, the patient refused further intervention and died of high leukocyte syndrome four months later. The second case was a 23-year-old woman who was diagnosed with acute B lymphoblastic leukemia and received HLA-identical sibling allo-HSCT. Although 62% of blasts were found in her left iliac marrow on day +122, 0 % of blasts were found on a sample obtained from the right iliac crest on day +128. Whole-body 18F-FDG PET/CT scans confirmed that the leukemic infiltration in her bone marrow was asymmetric. Considering the higher leukemic burden on the left, we chose the left posterior iliac crest aspiration for further response evaluation. After chemotherapy combined with donor lymphocyte infusion, she achieved transient hematologic complete remission. She died of septic shock with heart failure at +258 days after allo-HSCT before infusion of anti-CD19 donor chimeric antigen receptor T cells. Conclusions: To our knowledge, these are the first case reports of asymmetric bone marrow infiltration of blasts in acute leukemia patients after allo-HSCT. Bilateral posterior iliac crest aspirations or 18F-FDG-PET/CT scans may help distinguish such distribution. If discordant bone marrow specimens are observed, physicians should restrict future bone marrow studies to the more involved side.

Preprint ARTICLE | doi:10.20944/preprints202310.1156.v1

Differences in Response by Immunosuppressed Kidney Transplant Patients to Moderna mRNA-1273 versus Pfizer-BioNTech

Dulat Bekbolsynov, Andrew Leland Waack, Camryn Buskey, Shalmali Sandeep Bhadkamkar, Keegan Rengel, Winnifer Petersen, Mary Lee Brown, Tanaya Sparkle, Dinkar Kaw, Fayeq Jeelani Syed, Saurabh Chattopadhyay, Ritu Chakravarti, Sadik Khuder, Beata Mierzejewska, Michael Rees, Stanislaw Stepkowski

Subject: Medicine And Pharmacology, Transplantation Keywords: SARS-CoV-2; kidney transplantation; mRNA vaccine; seropositivity; immunocompromised.

Online: 19 October 2023 (04:48:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0646.v1

Biological Membrane with Antimicrobial Activity Based on Lyophilized and Decellularized Bovine Pericardium Impregnated with Vancomycin or Silver Nanoparticles

Daniele de Fátima Fornazari Collatusso, Leticia Ramos Dantas, Paula Hansen Suss, Jaime Lopes Rocha, Marcelo de Paula Loureiro, Felipe Francisco Tuon

Subject: Medicine And Pharmacology, Transplantation Keywords: pericardium; decellularization; bovine; vancomycin; silver nanoparticles

Online: 11 July 2023 (08:20:36 CEST)

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Preprint ESSAY | doi:10.20944/preprints202404.0313.v1

A Mathematical Model of Disease

Marc Schnitzler

Subject: Medicine And Pharmacology, Transplantation Keywords: alloreactivity; fetal microchimerism; relativity; set theory; non-communicable diseases; autoimmunity; diabetes; arteriosclerosis; cancer

Online: 4 April 2024 (15:55:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202312.2125.v1

Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation: A Pre-clinical Perspective

Tanvir Hasan, Ajay Ratan Pasala, Dhuha Hassan, Justine Hanotaux, David S Allan, Harinad B Maganti

Subject: Medicine And Pharmacology, Transplantation Keywords: Hematopoietic stem cell transplantation; xeno-transplantation; homing; engraftment; clonal hematopoiesis; clonal leukemogenesis; competitive repopulation.

Online: 27 December 2023 (13:57:18 CET)

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Preprint REVIEW | doi:10.20944/preprints202308.1747.v1

Adverse Drug Events after Kidney Transplantation

Lionel Rostaing, Thomas Jouve, Florian Terrec, Paolo Malvezzi, Johan Noble

Subject: Medicine And Pharmacology, Transplantation Keywords: kidney transplantation; immunosuppression; adverse drug event; nephrotoxicity; NODAT; anemia; leukopenia; viral reactivation; hypertension; dyslipidemia

Online: 24 August 2023 (13:34:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0386.v1

The Power of Nutraceuticals Fighting Liver Ischemia–Reperfusion Injury Through Apoptosis Reduction

Carlos Andrés Pantanali, Vinicius Rocha-Santos, Márcia Saldanha Kubrusly, Inar Alves Castro, Luiz Augusto Carneiro-D’Albuquerque, Flávio Henrique Galvão

Subject: Medicine And Pharmacology, Transplantation Keywords: nutraceuticals; liver; ischemia-reperfusion injury; apoptosis

Online: 6 May 2023 (05:46:56 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202304.0111.v2

Chemorepulsion of Host Immune Cells for Xenotransplantation

Michael Renteln

Subject: Medicine And Pharmacology, Transplantation Keywords: Xenotransplantation; chemorepulsion; adaptive immunity; innate immunity; dysregulated coagulation; complement cascade

Online: 10 April 2023 (09:14:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0942.v1

Aging With a Liver Graft: Analysis of Very Long‐ Term Survivors after Liver Transplantation

Paolo De Simone, Jessica Bronzoni, Caterina Martinelli, Juri Ducci, Daniela Campani, Stefano Gitto, Piero Marchetti, Giandomenico Biancofiore

Subject: Medicine And Pharmacology, Transplantation Keywords: liver transplantation; long term survival; aging; immunosuppression

Online: 11 January 2024 (14:54:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.0452.v1

Impact on Kidney Transplantation of the Percentage of T Lymphocytes Isolated from Hepatic Perfusate of Multi-Organ Deceased Brain Donors

Duilio Pagano, Ester Badami, Giovanni Zito, Pier Giulio Conaldi, Ivan Vella, Barbara Buscemi, Giandomenico Amico, Rosalia Busà, Paola Salis, Sergio Li Petri, Fabrizio Di Francesco, Sergio Calamia, Pasquale Bonsignore, Alessandro Tropea, Caterina Accardo, Salvatore Piazza, Salvatore Gruttadauria

Subject: Medicine And Pharmacology, Transplantation Keywords: : Kidney transplantation; hepatic perfusate; deceased brain donors; T lymphocytes

Online: 8 May 2023 (05:16:31 CEST)

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Background: Hepatic interstitial T-lymphocytes (T-Li), Natural Killer (NK) and NK-T cells play an important role in both innate and adaptive immunity and contribute to the regulation of ischemia/reperfusion injury (IRI) after transplantation of abdominal organ. Methods: The cellular concentrations and phenotypes of NK, T-Li, NK-T were analyzed retrospectively in a consecutive series of hepatic perfusates after surgical removal of whole livers on the bench previously collected from adult multi-organ donors after brain death. (DBD), and compared with the demographic and pathological characteristics of the patients transplanted at our Institute with kidneys taken from the same donors. The liver interstitial cells were purified from the perfusate by density gradient centrifugation and the phenotype was determined by flow cytometric investigation using the following immunological markers: CD3, CD4, CD8 and CD56 in order to determine the relative percentage of T-Li, NK-T and NK cells. Results: The perfusates of 42 DBDs, and the related clinical outcome of kidney transplant recipients from 2010 to 2020, were analyzed. T-Li were significantly associated with the time in days of delayed functional recovery of transplanted kidneys (DGF) (p = 0.02), to onset of secondary infection from Cytomegalovirus (p = 0.03). On COX analysis, percent cell concentration of T-Li and time to DGF were significantly associated with an increased relative risk (HR) of organ survival (HR = 1.038, p = 0.04; and HR = 1.029, p = 0.01, respectively). The specificity of the NK and NK-T cell proportions were not associated with any relevant clinical outcomes in kidney transplant patients. Conclusions: The present study points to a new potential role of T-Li cells detected in the context of liver perfusate DBD, and could detect potential impacts in organ allocation, surgical harvesting techniques and in the analysis of IRI pathophysiological events after kidney transplants from multi-organ DBDs.

Preprint CASE REPORT | doi:10.20944/preprints202312.1230.v1

Epstein-Barr Virus-negative Diffuse Large B Cell Lymphoma in a X-linked Severe Combined Immunodeficiency Patient: A Very Rare Condition

Dina Rochate, Sara Duarte, Rita S. Gomes, Rita Pinho Peixeiro, João Vaz Silva, Ângelo Rodrigues, Luís Leite, Rosa Branca, Sónia Lemos, Joana Guimarães, Susana Roncon, Ana Maia Ferreira, Carlos Pinho Vaz

Subject: Medicine And Pharmacology, Transplantation Keywords: DLBCL; X-linked SCID; allogeneic stem cell transplantation; infant; lymphoma

Online: 18 December 2023 (13:00:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.2246.v1

Serological Antibodies Against Membrane Antigens As Potential Biomarkers of Immune Disorders

Leidi Hernandez-Suarez, June Egiguren-Ortiz, Eguzkiñe Diez-Martin, Roberto Fernández, Aitor Echevarría, Egoitz Astigarraga, Cristina Miguélez, Andoni Ramirez-Garcia, Gabriel Barreda-Gomez

Subject: Medicine And Pharmacology, Transplantation Keywords: inflammation; autoimmune disorders; reactive antibodies; microarray

Online: 29 December 2023 (05:26:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1795.v1

Socioeconomic Deprivation Is Associated with Worse Outcomes after Adult Liver Transplantation

Paolo De Simone, Jessica Bronzoni, Quirino Lai, Caterina Martinelli, Juri Ducci, Daniela Campani, Stefano Gitto, Piero Marchetti

Subject: Medicine And Pharmacology, Transplantation Keywords: liver transplant; poverty; inequalities; healthcare; results

Online: 25 January 2024 (07:12:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0710.v1

CYP3A5*3 and CYP3A4*22 Cluster Polymorphism Effects on LCP-Tac Tacrolimus Exposure: Population Pharmacokinetic Approach

Zeyar Mohammed Ali, Marinda Meertens, Beatriz Fernández, Pere Fontova Palé, Anna Vidal-Alabró, Raul Rigo-Bonnin, Edoardo Melilli, Josep M Cruzado, Josep M Grinyó, Helena Colom, Nuria Lloberas

Subject: Medicine And Pharmacology, Transplantation Keywords: Tacrolimus; LCP-Tac; Population Pharmacokinetics; CYP3A5; CYP3A4; ABCB1; Renal transplantation; stable adult patients; Immunosuppression

Online: 11 October 2023 (12:16:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.1844.v1

Multilineage-Differentiating Stress-Enduring Cells: A Powerful Tool for Tissue Damage Repair

Hanyun Que, Erziya Mai, Yanting Hu, Hong Li, Wenxin Zheng, Yuchen Jiang, Feiruo Han, Xuedong Li, Puyang Gong, Jian Gu

Subject: Medicine And Pharmacology, Transplantation Keywords: tissue regeneration; non-tumorigenic; S1P-S1P receptor 2 system; preferential homing; pluripotent stem cell

Online: 26 January 2024 (08:00:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1268.v1

Prevention of Delayed Graft Function in Kidney Transplant Recipients by Continuous Infusion of Prostaglandin-Analogue Iloprost: A Single-Center Prospective Study

Massimiliano Veroux*, Floriana Sanfilippo, Giuseppe Roscitano, Martina Maria Giambra, Alessia Giaquinta, Giordana Riccioli, Domenico Zerbo, Daniela Corona, Massimiliano Sorbello, Pierfrancesco Veroux

Subject: Medicine And Pharmacology, Transplantation Keywords: Kidney transplantation; Marginal Donor; Cold Ischemia Time; Donor Age; Acute kidney Injury; Deceased Donor; Graft Survival; Patient Survival

Online: 18 December 2023 (06:07:16 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.1321.v1

Updates and Expert Opinion in Liver Transplantation for Gastrointestinal Malignancies

Alexander H. Shannon, Samantha M. Ruff, Austin D. Schenk, W. Kenneth Washburn, Timothy M. Pawlik

Subject: Medicine And Pharmacology, Transplantation Keywords: Transplant Oncology; Liver Transplant; Gastrointestinal Malignancies

Online: 19 June 2023 (08:33:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1710.v1

Expression of Rejection-Associated Transcripts in Early Protocol Renal Transplant Biopsies Are Associated with Tacrolimus Exposure and Graft Outcome

Betty Chamoun, Irina B. Torres, Alejandra Gabaldon, Thomas Jouvé, Maria Meneghini, José M Zuñiga, Joana Sellares, Manel Perello, Daniel Serón, Oriol Bestard, Francesc Moreso

Subject: Medicine And Pharmacology, Transplantation Keywords: renal transplantation; biopsies; rejection; gene expression; tacrolimus

Online: 23 January 2024 (16:30:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1063.v1

COVID-19 Outcomes in Kidney Transplant Recipients in a German Transplant Center

Michael Mikhailov, Klemens Budde, Fabian Halleck, Georgios Eleftheriadis, Marcel Naik, Eva Schrezenmeier, Friederike Bachmann, Mira Choi, Wiebke Duettmann, Ellen Von Hoerschelmann, Nadine Koch, Lutz Liefeldt, Christian Lücht, Henriette Straub-Hohenbleicher, Johannes Waiser, Ulrike Weber, Bianca Zukunft, Bilgin Osmanodja

Subject: Medicine And Pharmacology, Transplantation Keywords: kidney transplant recipients, immunosuppression, vaccination, SARS-CoV-2, COVID-19, Omicron

Online: 15 August 2023 (08:32:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202302.0242.v1

Vaginal Microbiota Transplantation: Possible Mechanisms and Future Perspectives

Maimaiti Tuniyazi, Shuang Li, Yunhe Fu, Xiaoyu Hu, Naisheng Zhang

Subject: Medicine And Pharmacology, Transplantation Keywords: vaginal microbiota transplantation; dysbiosis; treatment; mechanism

Online: 14 February 2023 (09:23:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202304.0805.v1

Torque Teno Virus load predicts opportunistic infections after kidney transplantation but is not associated with maintenance immunosuppression exposure.

Lucía Cañamero, Adalberto Benito-Hernandez, Elena González, Clara Escagedo, María Rodríguez-Vidriales, María del Mar García-Saiz, Rosalía Valero, Lara Belmar, María Angeles De Cos, Juan Carlos Ruiz, Emilio Rodrigo

Subject: Medicine And Pharmacology, Transplantation Keywords: acute rejection, immunosuppression, infection, kidney transplantation; monitoring, Torque Teno virus

Online: 23 April 2023 (14:07:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1027.v1

Everolimus Mitigates the Risk of Hepatocellular Carcinoma Recurrence after Liver Transplantation

Paolo De Simone, Arianna Precisi, Quirino Lai, Juri Ducci, Daniela Campani, Piero Marchetti, Stefano Gitto, Laura Crocetti

Subject: Medicine And Pharmacology, Transplantation Keywords: liver transplantation; immunosuppression; everolimus; hepatocellular carcinoma; recurrence

Online: 15 January 2024 (10:26:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.2083.v1

Achieving Gender Equity amongst the Liver Transplantation Medical and Surgical Workforce: Why Ongoing Actions Will Be Required

Deborah Verran

Subject: Medicine And Pharmacology, Transplantation Keywords: liver transplantation; workforce; gender; equity; healthcare; academia; barriers; policy development; surgery; gastroenterology

Online: 30 January 2024 (05:55:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.0011.v1

Update on Desensitization Strategies and Drugs on Hyperimmune Patients for Kidney Transplantation

Maurizio Salvadori

Subject: Medicine And Pharmacology, Transplantation Keywords: Desensitization; Donor specific antibodies; HLA system; antibodies identification; B cells; Plasma cells; Complement; New drugs; Desensitization; Donor specific antibodies; HLA system; B cells; Plasma cells; Complemennt; New drugs

Online: 1 June 2023 (03:17:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1286.v1

Sequential Regorafenib or Nivolumab Therapy in Recurrent Hepatocellular Carcinoma with Sorafenib Failure in Liver Transplant Patients Does Not Improve Prognosis

Jieun Kwon, Jongman Kim, Sang Oh Yun, Sunghae Park, Manuel Lim, Jaehun Yang, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh

Subject: Medicine And Pharmacology, Transplantation Keywords: Graft rejection; survival; mortality; chemotherapy

Online: 19 September 2023 (10:22:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0593.v1

The Risk of Acute or Reactivated Hepatitis E Virus Infection at a Liver Transplant Center in Brazil: Observational Cohort Study

Michelle Zicker, João R.R. Pinho, Eliane A.R. Welter, Bianca D. Guardia, Paulo G.T.M. Da Silva, Leonardo Bonilla Da Silveira, Luís F.A. Camargo

Subject: Medicine And Pharmacology, Transplantation Keywords: hepatitis E; liver transplantation; prevalence; incidence; natural history; Brazil

Online: 11 December 2023 (03:08:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1999.v1

Toxoplasma gondii Infection in Patients Submitted to Liver Transplantation

Gabriela Beltrame Pintos, Francielly Camilla Bazílio Laurindo Pires, Rita Cássia Martins Alves Silva, Francisco Inaldo Mendes Silva Junior, Nathália Zini, Renato F Da Silva, Luiz Carlos De Mattos, Cinara Cássia Brandão

Subject: Medicine And Pharmacology, Transplantation Keywords: Toxoplasma gondii; solid organ transplantation; liver transplantation; infection

Online: 30 November 2023 (15:03:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1239.v1

Combined Score Based on Match between Donor and Recipient in Age-Sex-Body Mass Index Is Related to the Evolution of the Graft after Renal Transplantation

Sergio Barroso Hernández, Álvaro Álvarez López, Elena García de Vinuesa Calvo, Jorge Alberto Rodríguez Sabillón, Teresa de Jesús Giraldo Rúa, Román Hernández Gallego, Jaime Hernán Merino, Miguel Nuno Petrucci Mauricio, Nicolás Roberto Robles Pérez-Monteoliva

Subject: Medicine And Pharmacology, Transplantation Keywords: Renal transplantation; donor-recipient matching; matching non-HLA; matching in age, gender and body mass index; renal graft outcome.

Online: 20 October 2023 (08:14:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0156.v1

Postoperative Bloodstream Infection Is Associated with Early Vascular Complications in Pediatric Liver Transplant Recipients with Biliary Atresia

Ho Jong Jeon, Ji-Man Kang, Hong Koh, Myoung Soo Kim, Kyong Ihn

Subject: Medicine And Pharmacology, Transplantation Keywords: bacteremia; vascular complication; pediatric liver transplant; biliary atresia; bloodstream infection

Online: 4 October 2023 (04:51:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.2103.v1

Role of ADAMTS13, von Willebrand factor cleaving protease, in liver ischemia-reperfusion injury: Proposal of hepatic thrombotic microangiopathy

Hirofumi Hirao, Toyonari Kubota

Subject: Medicine And Pharmacology, Transplantation Keywords: ADAMTS13, von Willebrand factor; hepatic stellate cell; thrombocytopenia; liver transplantation

Online: 30 January 2024 (10:25:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1523.v1

Liver Transplantation for Hepatocellular Carcinoma beyond Milan Criteria

Oliver Rohland, Lea Freye, Laura Schwenk, Aladdin Ali-Deeb, Michael Ardelt, Astrid Bauschke, Utz Settmacher, Falk Rauchfuß, Felix Dondorf

Subject: Medicine And Pharmacology, Transplantation Keywords: hepatocellular carcinoma; Milan criteria; living-donor liver transplantation; transplant outcome

Online: 22 January 2024 (10:08:45 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.1482.v1

Role of B Cells beyond Antibodies in Hbv-Induced Oncogenesis: Fulminant Cancer in Common Variable Immunodeficiency –Clinical and Immunotransplant Implications

Przemyslaw Zdziarski, Andrzej Gamian

Subject: Medicine And Pharmacology, Transplantation Keywords: IgG; protective level; vaccination; B cell; large granular lymphocytes (LGLs); common variable immunodeficiency (CVID); replacement therapy; hepatitis B immune globulins (HBIG); serum sickness; Hepatitis B virus (HBV); oncogenesis; hepatocellular carcinoma

Online: 20 December 2023 (10:53:25 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202304.0111.v1

Chemorepulsion of Host Immune Cells for Xenotransplantation

Michael Renteln

Subject: Medicine And Pharmacology, Transplantation Keywords: Xenotransplantation; chemorepulsion; adaptive immunity; innate immunity; dysregulated coagulation; complement cascade

Online: 7 April 2023 (04:10:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1782.v1

Nuclear Factor-κB Decoy Oligodeoxynucleotide Attenuates Cartilage Resorption in vitro

Hitoshi Nemoto, Koichi Masuda, Deborah Watson, Daisuke Sakai

Subject: Medicine And Pharmacology, Transplantation Keywords: nuclear factor-κb; decoy oligodeoxynucleotide; cartilage; resorption

Online: 27 October 2023 (12:54:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0521.v1

A Gelatin Hydrogel Nonwoven Fabric Enhances Subcutaneous Islet Engraftment in Rats

Ryusuke Saito, Akiko Inagaki, Yasuhiro Nakamura, Takehiro Imura, Norifumi Kanai, Hiroaki Mitsugashira, Yukiko Endo Kumata, Takumi Katano, Shoki Suzuki, Kazuaki Tokodai, Takashi Kamei, Michiaki Unno, Kimiko Watanabe, Yasuhiko Tabata, Masafumi Goto

Subject: Medicine And Pharmacology, Transplantation Keywords: islets; gelatin hydrogel nonwoven fabrics; subcutaneous transplantation; extracellular matrix; neovascularization; rats

Online: 7 December 2023 (11:41:33 CET)

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Medicine and Pharmacology