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Preprint ARTICLE | doi:10.20944/preprints201903.0031.v1

Organ-on-Chip In Development:Towards a roadmap for Organs-on-Chip

M. Mastrangeli, S. Millet, the ORCHID partners, J. van den Eijnden-van Raaij

Subject: Engineering, Bioengineering Keywords: Organ-on-Chip, tissue engineering, microfluidic technology

Online: 4 March 2019 (10:11:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0486.v1

A Simple and Cheap Aerosol Penetrometer for Filter Testing Using an Electronic Cigarette

Sebastian Lifka, Ivan Ponomarev, Agnes Weth, David Baumgartner, Bernd Lamprecht, Werner Baumgartner

Subject: Engineering, Bioengineering Keywords: Filter; face masks; penetrometer; electronic cigarette; COVID-19; light scattering detector

Online: 21 December 2020 (09:34:50 CET)

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Preprint REVIEW | doi:10.20944/preprints202202.0050.v1

Neural Implants: A Review Of Current Trends And Future Perspectives

Halima-Tul-Rokeya Mim, Munima Haque, Salman Khan Promon

Subject: Engineering, Bioengineering Keywords: Neuroprosthetics; Brain Computer Interface; Neural Implants; Deep Brain Stimulation

Online: 3 February 2022 (11:06:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0169.v1

Thermal Signature Based Sleep Analysis Sensor

Ali Seba, Dan Istrate, Toufik Guettari, Adrien Ugon, Andrea Pinna, Patrick Garda

Subject: Engineering, Bioengineering Keywords: thermopile sensor; actimetry; thermal camera, data classification; tele-medicine; polysomnography;

Online: 26 April 2017 (12:27:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201707.0065.v1

An Electromagnetically Actuated Double-Sided Cell-Stretching Device for Mechanobiology Research

Harshad Kamble, Raja Vadivelu, Mathew Barton, Kseniia Boriachek, Ahmed Munaz, Sungsu Park, Muhammad J. A. Shiddiky, Nam-Trung Nguyen

Subject: Engineering, Bioengineering Keywords: Biomedical Engineering, Cell Stretching, Mechanobiology.

Online: 24 July 2017 (10:04:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0022.v1

A Simple, Cost-Effective Sensor for Detecting Lead Ions in Water Using Under-Potential Deposited Bismuth Sub-Layer with Differential Pulse Voltammetry (DPV)

Yifan Dai, Chung Chiun Liu

Subject: Engineering, Bioengineering Keywords: under-potential deposition; bismuth sub-layer; lead ions; DPV

Online: 4 April 2017 (10:43:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0457.v1

Sensor-Based Sleep Quality Index (SB-SQI): A New Metric to Examine the Association of Office Workstation Type on Stress and Sleep

Hyoki Lee, Javad Razjouyan, hung nguyen, Casey Lindburg, Karthik Srinivasan, Brian Gilligan, Kelli Canada, Amir Sharafkhaneh, Matthias Mehl, Faiz Currim, Sudh Ram, Melissa Lunden, Judith Heerwagen, Kevin Kampschroer, Esther Sternberg, Bijan Najafi

Subject: Engineering, Bioengineering Keywords: Sleep, Office workers, office workstation, wellbeing, stress, physical activity, wearables, digital health, sleep quality index, tracking sleep quality, workstation types, accelerometry, heart rate variability

Online: 27 August 2018 (11:33:23 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202207.0329.v1

Biomanufacturing for Space-Exploration – What to Take and When to Make

Nils J.H. Averesch, Aaron J. Berliner, Shannon N. Nangle, Spencer Zezulka, Gretchen L. Vengerova, Davian Ho, Cameran A. Casale, Benjamin A.E. Lehner, Jessica E. Jessica Snyder, Kevin B. Clark, Lewis R. Dartnell, Craig S. Criddle, Adam P. Arkin

Subject: Engineering, Bioengineering Keywords: in-space biomanufacturing; space synthetic biology; space bioprocess engineering; biological life-support systems; in situ resource utilization; circular economy

Online: 21 July 2022 (11:01:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201707.0002.v1

Optimization of Bioreactor Cultivation Parameters by Taguchi Orthogonal Array Design for Enhanced Prodigiosin Production

Amera Elmenshawey, Ahmed Abdelrazak, Amr M. Mowafey, Yehia Osman

Subject: Engineering, Bioengineering Keywords: Bioreactor, Taguchi, Prodigiosin, Serratia, Process Development

Online: 3 July 2017 (17:13:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0124.v1

Assessing and Resolving Model Misspecifications in Metabolic Flux Analysis

Rudiyanto Gunawan, Sandro Hutter

Subject: Engineering, Bioengineering Keywords: metabolic flux analysis, model misspecification, constraint-based model, stoichiometric model, Chinese hamster ovary cell culture

Online: 16 March 2017 (17:38:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201706.0079.v1

RESPIRE: A Spectral Kurtosis-based Method to Extract Respiration Rate from Wearable PPG Signals

Hari Dubey

Subject: Engineering, Bioengineering Keywords: wearable; photoplethysmography; spectral kurtosis; extreme learning machine (ELM) regression; respiration rate; cardiovascular diseases (CVD)

Online: 16 June 2017 (10:45:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints201806.0292.v1

3D Printed Biosensor Arrays for Medical Diagnostics

Mohamed Sharafeldin, Abby Jones, James F. Rusling

Subject: Engineering, Bioengineering Keywords: 3D printing; diagnostics; optics; bioprinting, electronics, microfluidics

Online: 19 June 2018 (10:41:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201903.0038.v1

Miscanthus x giganteus Stem versus Leaf-derived Lignins Differing in Monolignol Ratio and Linkage

Michel Bergs, Georg Völkering, Thorsten Kraska, Ralf Pude, Xuan Tung Do, Peter Kusch, Yulia Monakhova, Christopher Konow, Margit Schulze

Subject: Engineering, Bioengineering Keywords: biomass; chemometrics, genotype; HSQC NMR; lignin; Miscanthus X giganteus; monolignol ratio; principal component analysis

Online: 4 March 2019 (10:30:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0220.v1

Genetic Optimization Algorithm for Metabolic Engineering Revisited

Tobias B. Alter, Lars M. Blank, Birgitta E. Ebert

Subject: Engineering, Bioengineering Keywords: metabolic strain design; heuristic optimization; constraint-based modeling

Online: 27 March 2018 (05:55:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0184.v1

Distillery Wastewater as a Sustainable Medium for Microalgae Production

Viviana Quintero-Dallos, Janet Bibiana García-Martínez, Jefferson Eduardo Contreras-Ropero, Crisostomo Barajas-Ferrerira, Andrés Fernando Barajas-Solano, Roberto Lavecchia, Antonio Zuorro

Subject: Engineering, Bioengineering Keywords: distillery wastewater; vinasse; heterotrophic cultures; biorefinery; Chlorella vulgaris

Online: 19 June 2019 (12:32:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0005.v1

Operational Monitoring and Mass Balance in the Biodegradation of Oil for Two Scenarios: Experimental Plant of Active Sludge and Aerobic Digestor

Pedro Cisterna, Patricia Arancibia

Subject: Engineering, Bioengineering Keywords: Biodegradation; fats and oils; activated sludge

Online: 2 October 2017 (08:51:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints201809.0150.v1

Silicon Photonic Biosensors Using Label-Free Detection

Enxiao Luan, Hossam Shoman, Daniel M. Ratner, Karen C. Cheung, Lukas Chrostowski

Subject: Engineering, Bioengineering Keywords: silicon photonics; evanescent optical field sensor; label-free SOI biosensor; Mach-Zehnder interferometer; ring resonator; photonic crystal; Bragg grating; sub-wavelength grating; lab-on-a-chip; microfluidics

Online: 10 September 2018 (05:10:49 CEST)

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Preprint REVIEW | doi:10.20944/preprints201809.0336.v1

A Review on Synthesis and Characterization of Biomass-Derived Carbons for Adsorption of Emerging Contaminants from Water

Jorge Bedia, Manuel Peñas-Garzón, Almudena Goméz-Avilés, Juan José Rodríguez, Carolina Belver

Subject: Engineering, Bioengineering Keywords: Adsorption; Emerging contaminants; Biomass; Biochar; Activated carbon

Online: 18 September 2018 (09:06:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202112.0401.v2

Space Bioprocess Engineering on the Horizon

Aaron Berliner, Isaac Lipsky, Davian Ho, Jacob Hilzinger, Gretchen Vengerova, George Makrygiorgos, Matthew McNulty, Kevin Yates, Nils Averesch, Charles Cockell, Tyler Wallentine, Lance Seefeldt, Craig Criddle, Somen Nandi, Karen McDonald, Amor Menezes, Ali Mesbah, Adam Arkin

Subject: Engineering, Bioengineering Keywords: space systems bioengineering; biomanufacturing; space bioprocess engineering; biotransformation human exploration; in situ resource utilization; life support systems; biomanufacturing; space policy

Online: 27 December 2021 (15:48:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0403.v1

In-Silico Study of Some Natural Plant Phyto-compounds for the Identification of Novel Potent Cholinesterase Inhibitors Against Alzheimer Disease

Dhiraj Kumar, Sanjana Bhagat

Subject: Engineering, Bioengineering Keywords: Phytocompounds; Binding energy; ADMET; Molecular docking

Online: 19 August 2021 (12:05:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0396.v1

Modeling the Separation of Microorganisms in Bioprocesses by Flotation

Stefan Schmideder, Christoph Kirse, Julia Hofinger, Sascha Rollié, Heiko Briesen

Subject: Engineering, Bioengineering Keywords: flotation; separation of microorganisms; bioseparation; heteroaggregation; population balance modeling; coupling of aggregation and CFD; model comparison

Online: 22 August 2018 (11:58:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202202.0176.v1

Recent Advances of Natural Cellulosic Non-Woven Scaffolds for Tissue Engineering

Mohammadreza Aghazadeh, Sheyda Delfanian, Pouria Aghakhani, Shahin Homaeigohar, Atefeh Alipour, Hosein Shahsavarani

Subject: Engineering, Bioengineering Keywords: Polymeric Biomaterials; Natural Cellulose; Tissue Engineering; Differentiation; Bone Regeneration; Skin Regeneration; Cardiac Regeneration; Vascular Regeneration; Neural Regeneration

Online: 14 February 2022 (14:02:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0291.v1

Whole Virus Detection Using Paper Potentiometry and Aptamers

Subhashish Dolai, Massood Tabib-Azar

Subject: Engineering, Bioengineering Keywords: paper based sensor; whole virus; Zika; aptamer

Online: 20 February 2020 (07:24:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201905.0050.v1

Scaffolds with a High Surface Area-to-Volume Ratio and Cultured Under Fast Flow Perfusion Result in Optimal O₂ Delivery to the Cells in Artificial Bone Tissues

Thanh Danh Nguyen, Olufemi E. Kadri, Vassilios Sikavitsas, Roman S. Voronov

Subject: Engineering, Bioengineering Keywords: oxygen delivery; optimization; mass transfer; transport; bone tissue engineering; computational fluid dynamics; lattice Boltzmann method; scaffold design; culturing protocol; Lagrangian scalar tracking

Online: 6 May 2019 (10:37:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0193.v1

In Vitro Investigation of Gas Embolism in Microfluidic Networks Mimicking Microvasculature

Mohammad Mahdi Mardanpour, Ayyappasamy Sudalaiyadum Perumal, Zahra Mahmoodi, Karine Baassiri, Gala Montiel Rubies, Kenneth M. LeDez, Dan V. Nicolau

Subject: Engineering, Bioengineering Keywords: gas embolism; microfluidics; microvasculature; flow pattern

Online: 15 March 2022 (03:13:48 CET)

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Preprint REVIEW | doi:10.20944/preprints202303.0072.v1

Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell Therapies

Frances Rocamora, Angelo G Peralta, Seunghyeon Shin, James Sorrentino, Mina Wu, Eric A Toth, Thomas R Fuerst, Nathan E Lewis

Subject: Engineering, Bioengineering Keywords: glycosylation, glycoengineering, biologic, therapeutic protein, gene therapy, cell-based therapy, monoclonal antibody

Online: 3 March 2023 (10:43:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints201907.0303.v1

About the Accuracy and Problems of Consumer Devices in the Assessment of Sleep

Mohamed S. Ameen, Lok Man Cheung, Theresa Hauser, Michael Hahn, Manuel Schabus

Subject: Engineering, Bioengineering Keywords: wrist-worn devices; sleep trackers; activity trackers; sleep classification; polysomnography

Online: 26 July 2019 (17:13:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints201811.0061.v1

Versatility of Reverse Micelles: From Biomimetic Model to Nano(Bio)Sensors Design

Melania-Liliana Arsene, Ana-Maria Gurban, Maria-Luiza Jecu, Mihaela Doni

Subject: Engineering, Bioengineering Keywords: reverse micelles, biomimetic, confinement, water dynamics, nanoparticles, nano(bio) sensors

Online: 2 November 2018 (13:25:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0587.v1

Magneto-Optic Surface Plasmon Resonance Ti/Au/Co/Au/Pc Configuration and Sensitivity

Conrad Rizal

Subject: Engineering, Bioengineering Keywords: Ti/Au/Co/Au; X-ray diffraction; MOSPR; sensitivity; polycarbonate plastics

Online: 30 July 2018 (11:55:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0334.v1

Smart Optical Catheters for Epidurals

Benito Carotenuto, Armando Ricciardi, Alberto Micco, Ezio Amorizzo, Marco Mercieri, Antonello Cutolo, Andrea Cusano

Subject: Engineering, Bioengineering Keywords: Fiber optics sensors; Fiber Bragg gratings; Clinical applications; Medical optics instrumentation

Online: 24 May 2018 (05:57:50 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202202.0032.v1

User-View on Organ-on-a-Chip Technology

Mathias Busek, Aleksandra Aizenshtadt, Mikel Amirola Martinez, Ludivine Delon, Stefan Krauss

Subject: Engineering, Bioengineering Keywords: Organ-on-a-Chip (OoC); Micro-physiological systems (MPS); survey; usability; limitations; disease models; drug testing

Online: 2 February 2022 (12:20:19 CET)

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Preprint REVIEW | doi:10.20944/preprints202012.0562.v1

Visual Cortical Prosthesis : An Electrical Perspective

Léo Pio-Lopez, Romanos Poulkouras, Damien Depannemaecker

Subject: Engineering, Bioengineering Keywords: visual cortical prosthesis; brain-machine interface; electrical stimulation; prosthetic vision

Online: 22 December 2020 (12:52:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202106.0553.v1

A Non-invasive Detection Technique of Adenocarcinoma with the Use of Streptavidin-Coated Iron Nanoparticles and Biotinylated-Antibodies and the Primary-Secondary Approach

Aditi Venkatraman

Subject: Engineering, Bioengineering Keywords: Iron-oxide nanoparticles, primary-secondary method, diagnostics of cancer, A549 cell line, transferrin protein receptors, adenocarcinoma, biotin-streptavidin, biotinylated antibodies

Online: 23 June 2021 (09:17:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0470.v1

Linear and Nonlinear Dynamic Methods towards Investigating Proprioception Impairment in Non-specific Low Back Pain Patients

Seyed Mohammadreza Shokouhyan, Mehrdad Davoudi, Maryam Hoviattalab, Mohsen Abedi, Soha Bervis, Mohamad Parnianpour, Simon Brumagne, Kinda Khalaf

Subject: Engineering, Bioengineering Keywords: Posture control; low back pain; COP; proprioception; Recurrence Quantification Analysis; Vibrator

Online: 20 July 2020 (11:39:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201806.0039.v1

Identification and Characterization of Novel Fc-Binding Heptapeptides from Experiments and Simulations

Xiaoquan Sun, Justin Weaver, Sumith Ranil Wickramasinghe, Xianghong Qian

Subject: Engineering, Bioengineering Keywords: Protein A; Heptapeptide; M13 Phage-Display; ELISA; Fc; purification; docking; molecular dynamics simulations

Online: 4 June 2018 (12:03:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202001.0296.v1

The Science and Engineering of Stem Cell–Derived Organoids-Examples from Hepatic, Biliary, and Pancreatic Tissues

Ogechi Ogoke, Mitchell Maloy, Natesh Parashurama

Subject: Engineering, Bioengineering Keywords: stem cells; organoids; hepatocytes; pancreatic islets; cholangiocytes; organoid morphogenesis; organoid imaging

Online: 25 January 2020 (15:32:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints201909.0021.v1

Mild Hydrothermal Pretreatment of Microalgae for the Production of Biocrude with a Low N and O Content

Miriam Montero-Hidalgo, Juan J. Espada, Rosalía Rodríguez, Victoria Morales, Luis. F. Bautista, Gemma Vicente

Subject: Engineering, Bioengineering Keywords: Microalgae; hydrothermal liquefaction; pretreatment, low O and N biocrude

Online: 2 September 2019 (10:33:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0422.v1

Label-free, High-throughput Assay of Human Dendritic Cells from Whole-blood Samples with Microfluidic Inertial Separation Suitable for Resource-limited Manufacturing

Caffiyar Mohd Yousuff, Kue Peng Lim, Ismail Hussain Kamal Basha, Nor Hisham Hamid, Sok Ching Cheong, Eric Tatt Wei Ho

Subject: Engineering, Bioengineering Keywords: inertial spiral microfluidics; dendritic cell separation; resource-limited microfluidics

Online: 28 February 2020 (11:54:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202204.0088.v1

Signal Quality Valuation with Optimal Power Consumption and High Compression Ratio Method for Estimate Heart Rate Applied to Real-time PPG Measurement

Ngoc-Thang Bui, Tri Ho Minh, Bang Le-Huy Nguyen, Trong Toai Truong, Dinh Luong Le

Subject: Engineering, Bioengineering Keywords: Lossy/ lossless compression; Huffman coding; real-time PPG measurement; heart rate estimate, Message Queueing Telemetry Transport (MQTT); healthcare system

Online: 11 April 2022 (04:21:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0234.v1

Intensive Production of Carboxylic Acids Using Cl. butyricum in a Membrane Bioreactor (MBR)

Husnul Azan Tajarudin, Myrto-Panagiota Zacharof, Karnika Ratanapongleka, Paul M. Williams, Robert W. Lovitt

Subject: Engineering, Bioengineering Keywords: acetic acid; butyric acid; effluents; microfiltration; fermentation; MBR

Online: 13 August 2018 (16:56:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0022.v1

A Methodologic Approach for the Selection of Bio-Resorbable Polymers in the Development of Medical Devices: The Case of Poly(L-lactide-co-e-caprolactone)

Alberto Cingolani, Tommaso Casalini, Stefano Caimi, Antoine Klaue, Mattia Sponchioni, Filippo Rossi, Giuseppe Perale

Subject: Engineering, Bioengineering Keywords: electron beam; ethylene oxide; medical devices; polymers; sterilization

Online: 3 July 2018 (05:33:04 CEST)

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Preprint REVIEW | doi:10.20944/preprints202007.0284.v1

Sulfated Polysaccharides From Sea Algae as the Basis of Modern Biotechnologies for Creating Wound Coverings: Current Achievements and Coming Prospects

Boris Andryukov, Natalya Besednova, Tatyana Kuznetsova, Tatyana Zaporozhets, Svetlana Ermakova, Tatyana Zvyagintseva, Ekaterina Chengizova, Anna Gazha, Tatyana Smolina

Subject: Engineering, Bioengineering Keywords: seaweed; sulfated polysaccharides; alginates; fucoidans; carrageenans; ulvans; wound dressing; wounds

Online: 14 July 2020 (03:37:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0136.v1

Cells-In-Touch: 3D Printing in Reconstruction and Modelling of Microscopic Biological Geometries for Research and Education

Xavier Fitzpatrick, Alexey Fayzullin, Socrates Dokos, Anna Guller

Subject: Engineering, Bioengineering Keywords: 3D printing; microscopy; CAD; FDM; cell shape; cytoskeleton; tactile education; data visualization; modelling; Materialise Mimics; CiTo-3DP

Online: 10 May 2022 (10:10:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0490.v1

Magnetic Nanomaterials as Contrast Agents for MRI

Sofia Caspani, Ricardo Magalhaes, João P. Araujo, Celia T. Sousa

Subject: Engineering, Bioengineering Keywords: nanomaterials; iron oxide nanoparticles; magnetic nanodiscs; synthetic antiferromagnetic nanostructures; nanowires; contrast agents; MRI; theragnosis

Online: 28 April 2020 (08:53:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0482.v1

High-Throughput, Label-Free Isolation of White Blood Cells From Whole Blood Using Parallel Spiral Microchannels With U-Shaped Cross-Section

Amirhossein Mehran, Peyman Rostami, Mohammad Said Saidi, Bahar Firoozabadi, Navid Kashaninejad

Subject: Engineering, Bioengineering Keywords: WBC isolation; Spiral microchannels; Inertial microfluidics; Passive cell separation; High-throughput separation

Online: 29 September 2021 (09:35:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0294.v1

A Wearable Shear Force Transducer Based on Color Spectrum Analysis

Michael McGeehan, Michael E. Hahn, Salil Karipott, Keat Ghee Ong

Subject: Engineering, Bioengineering Keywords: Sensor; optoelectronics; shear; force; biomechanics; gait; wearables; healthcare

Online: 23 February 2022 (13:35:58 CET)

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Preprint REVIEW | doi:10.20944/preprints202003.0461.v1

The Evolution of Cell Free Biomanufacturing

Michael Vilkhovoy, Abhinav Adhikari, Sandra Vadhin, Jeffrey Varner

Subject: Engineering, Bioengineering Keywords: cell free protein synthesis; cell free metabolic engineering; metabolic modeling

Online: 31 March 2020 (22:24:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0412.v1

Application of the Gadidae Fish Processing Waste for Food Grade Gelatin Production

Nikita Yu. Zarubin, Elena N. Kharenko, Olga V. Bredikhina, Leonid O. Arkhipov, Konstantin V. Zolotarev, Anton N. Mikhailov, Valeriya I. Nakhod, Marina V. Mikhailova

Subject: Engineering, Bioengineering Keywords: fish processing waste; Alaska pollock; Pacific cod; fish gelatin; gelling component.

Online: 19 July 2021 (13:14:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201907.0128.v1

BCI Gaze Sensing Method Using Low Jitter Code Modulated VEP

Ibrahim Kaya, Jorge Bohorquez, Ozcan Ozdamar

Subject: Engineering, Bioengineering Keywords: gaze sensing; SSVEP; BCI; c-VEP; transient VEP; QSS-VEP; deconvolution

Online: 9 July 2019 (04:23:10 CEST)

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Working Paper REVIEW

About Model Validation in Bioprocessing

Vignesh Rajamanickam, Heiko Babel, Liliana Montano-Herrera, Alireza Ehsani, Fabian Stiefel, Stefan Haider, Beate Presser, Bettina Knapp

Subject: Engineering, Bioengineering Keywords: bioprocess models; model validation; model calibration; Quality by Design; mechanistical and statistical models; hybrid models; chemometric models; Biopharmaceutical engineering; regulatory guidance

Online: 10 May 2021 (09:57:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0080.v1

The Turmell-Meter: A Device for Ankle Joint Axis Estimation Appliyng Product of Exponentials

Óscar Agudelo, Ángel Valera, Julio Vargas-Riaño

Subject: Engineering, Bioengineering Keywords: anthropometry; biomechanics; coordinate measuring machines; in vivo; kinematics; mechanical sensors; sensor arrays; human ankle model, operational amplifiers; pose estimation; position measurement; rehabilitation robotics; biomedical informatics; product of exponentials formula; Riemmanian manifolds

Online: 7 February 2022 (11:50:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0409.v1

Comparison of Laminoplasty on Lordotic, Straight and Kyphotic Cervical Alignments Suggest Poor Outcomes for Kyphotic Cervical Alignment: Finite Element Analysis

Norihiro Nishida, Muzammil Mumtaz, Sudharshan Tripathi, Amey Kelkar, Justin Mendoza, Yogesh Kumaran, Vijay Goel

Subject: Engineering, Bioengineering Keywords: cervical alignment; cervical laminoplasty; spinal cord; finite element analysis; cervical spine biomechanics

Online: 31 March 2022 (13:58:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0230.v1

Optimised Design of An Arterial Network Model Reproduces Characteristic Central and Peripheral Hemodynamic Waveform Features in Young Adults

Avinash Kondiboyina, Hilary A. Harrington, Joseph J. Smolich, Michael M. H. Cheung, Jonathan P. Mynard

Subject: Engineering, Bioengineering Keywords: cardiovascular modelling; arterial haemodynamics; wave reflection

Online: 16 March 2022 (10:05:44 CET)

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Working Paper ARTICLE

Self-supporting Smart Air Filters based on PZT/PVDF Electrospun Nanofiber Composite Membrane

Weidong He, Yinghe Guo, Yi-bo Zhao, Fuze Jiang, Jean Schmitt, Yang Yue, Jingxian Liu, Junji Cao, Jing Wang

Subject: Engineering, Bioengineering Keywords: self-supporting; smart air filter; sensors; energy harvesting; anti-bacteria

Online: 10 July 2020 (03:51:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0467.v1

Towards Biohydrogen Separation Using Poly(ionic liquid)/ionic Liquid Composite Membranes

Andreia S.L. Gouveia, Lucas Ventaja, Liliana C. Tome, Isabel M. Marrucho

Subject: Engineering, Bioengineering Keywords: drogen purification; CO2/H2 separation; PIL–IL composite membranes; gas permeation properties

Online: 22 October 2018 (05:18:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints202007.0641.v1

Coronavirus Disease (COVID-19): Reviews, Applications, and Current Status

Tanweer Alam

Subject: Engineering, Bioengineering Keywords: COVID 19; IoT; Blockchain; Infection; Emerging Technologies; mHealth

Online: 26 July 2020 (16:45:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0054.v1

Robust PVC Identification by Fusing Expert System and Deep Learning

Zhipeng Cai, Tiantian Wang, Yumin Shen, Yantao Xing, Ruqiang Yan, Jianqing Li, Chengyu Liu

Subject: Engineering, Bioengineering Keywords: electrocardiogram; K-means clustering algorithm; premature ventricular contraction; rule-based decision algorithm

Online: 3 March 2022 (07:22:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0548.v1

Improved Lipophilicity and Aqueous Solubility Prediction With Composite Graph Neural Networks

Oliver Wieder, Mélaine Kuenemann, Marcus Wieder, Thomas Seidel, Christophe Meyer, Thierry Langer

Subject: Engineering, Bioengineering Keywords: AI; deep-learning; neural-networks; graph neural-networks; cheminformatics; molecular property; machine-learning; computational chemistry; lipophilicity; solubility

Online: 30 August 2021 (14:29:43 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.1117.v1

Perspectives for Using CO2 as a Feedstock for Biomanufacturing

Elif Kurt, Jiansong Qin, Alexandria R Williams, Youbo Zhao, Dongming Xie

Subject: Engineering, Bioengineering Keywords: Metabolic engineering; CO2 fixation; feedstock; biomanufacturing; electrochemical catalysis; microbial electrosynthesis

Online: 18 October 2023 (08:17:15 CEST)

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Microbial cell factories offer an eco-friendly alternative for transforming raw materials into commercially valuable products, primarily because of their reduced carbon impact compared to conventional industrial procedures. These systems often depend on lignocellulosic materials, mainly pentose and hexose sugars, richly available carbon reservoirs. Nevertheless, these resources might not always be efficient due to the limited supply, significant cost, and other considerable obstacles. One major hurdle when working with sugars derived from lignocellulosic biomass, especially glucose, is balancing carbon allocation to satisfy energy, cofactor, and other essential component needs for cellular proliferation while maintaining a robust yield. Furthermore, nearly half or more of this carbon is inevitably lost as CO2 during the biosynthesis processes, which serves to generate the energy necessary for maintaining cell growth and other regular metabolic activities. This carbon loss lowers the theoretical production yield and compromises the benefit of reducing greenhouse gas emissions – a fundamental advantage of biomanufacturing. This review paper posits the perspectives of using CO2 from atmosphere, industrial wastes, or the exhausted gases generated in microbial fermentation as a feedstock for biomanufacturing. Both one-step direct CO2 fixation or two-step indirect CO2 fixation and conversion strategies are discussed, which can minimize the carbon loss, significantly increase the carbon yield, and eventually achieve the carbon-neutral or -negative goals. The one-step strategy uses novel metabolic pathway design and engineering approaches to directly fix the CO2 via the pathway toward the synthesis of the desired fermentation products. Due to the limitation of the yield and efficiency in one-step CO2 fixation, the two-step strategy aims to completely avoid carbon loss in biomanufacturing by integrating a first electrochemical fixation of the exhausted CO2 into C1/C2 products such as formate, methanol, acetate, and ethanol and a second fermentation unit to utilize the CO2-derived C1/C2 chemicals or co-utilize both C5/C6 sugars and C1/C2 chemicals for product formation. The great potentials and challenges of using CO2 as a feedstock for further biomanufacturing are also discussed.

Preprint ARTICLE | doi:10.20944/preprints202004.0205.v1

Experimental Study and Validation of a Kinetic Scheme for Hydrothermal Carbonization Reactions

Fidel Vallejo, Luis A. Diaz-Robles, Jorge Poblete, Francisco Cubillos

Subject: Engineering, Bioengineering Keywords: hydrothermal carbonization; lignocellulosic biomass; reaction kinetic; nonlinear regression model; waste-to-energy

Online: 13 April 2020 (03:32:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202303.0237.v1

Advancements in Implantable Microelectrodes: Opportunities and Risks for Neural Interface Technology

Syed Adnan Ali, Rehan Khan

Subject: Engineering, Bioengineering Keywords: microelectrodes; brain implants; brain-computer interface; DBS; ECoG

Online: 13 March 2023 (15:37:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0322.v1

Novel Centroid Method for Robust Evaluation of Return Time of Reflected Waves in the Systemic Arterial Network

Avinash Kondiboyina, Joseph J Smolich, Michael MH Cheung, Jonathan P Mynard

Subject: Engineering, Bioengineering Keywords: wave reflection; cardiovascular modelling; arterial hemodynamics

Online: 24 March 2022 (05:21:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0442.v1

A Simulation Analysis of an Influenza Vaccine Production Plant in Areas of High Humanitarian Flow. A Case Study for the Region of Norte de Santander (Colombia)

Jefferson Eduardo Contreras-Ropero, Silvia Liliana Ruiz-Roa, Janet B. García-Martínez, Néstor A. Urbina-Suarez, Germán L. López-Barrera, Andrés F. Barajas-Solano, Antonio Zuorro

Subject: Engineering, Bioengineering Keywords: Modeling process; SuperPro Designer®; Cell Culture; Public health; Developing countries

Online: 28 October 2021 (15:16:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1580.v1

Challenging Post-Translational Modification in the Cell-Free Protein Synthesis System

Kassidy Porche, Claire Lanclos, Yong-Chan Kwon

Subject: Engineering, Bioengineering Keywords: Cell-free protein synthesis; Post-translational modification; Biomanufacturing; Disulfide bonds; Glycosylation

Online: 21 June 2023 (16:33:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0469.v1

The Application of Catalytic Processes on the Production of Algae-based Biofuels: A Review

Antonio Zuorro, Janet B. García-Martínez, Andrés F. Barajas-Solano

Subject: Engineering, Bioengineering Keywords: microalgae; thermochemical processing; biofuel and bioenergy; torrefaction; liquefaction; pyrolysis; gasification

Online: 21 August 2020 (04:24:54 CEST)

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Working Paper ARTICLE

Improved Lipophilicity and Aqueous Solubility Prediction With Composite Graph Neural Networks

Oliver Wieder, Mélaine Kuenemann, Marcus Wieder, Thomas Seidel, Christophe Meyer, Sharon D. Bryant, Thierry Langer

Subject: Engineering, Bioengineering Keywords: AI; deep-learning; neural-networks; graph neural-networks; cheminformatics; molecular property; machine-learning; computational chemistry; lipophilicity; solubility

Online: 1 October 2021 (14:29:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0160.v1

A Photolysis-assist Molecular Communication for Tumour Bio-sensing

Yue Sun, Huafeng Bian, Yifan Chen

Subject: Engineering, Bioengineering Keywords: Bio-Sensing; inter-symbol interference; molecular communication; synchronisation

Online: 11 March 2022 (04:43:21 CET)

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Preprint REVIEW | doi:10.20944/preprints202309.1312.v1

Physics-Driven Deep Learning for Computer Aided Diagnostics Tasks in Medical Imaging

Shira Nemirovsy-Rotman, Eyal Bercovich

Subject: Engineering, Bioengineering Keywords: deep learning; deep neural networks; robustness; stability; generalization; physics-driven learning; medical imaging; computer aided diagnostics

Online: 20 September 2023 (08:42:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0177.v1

Evaluation of Shrimp Waste Valorization Combining Computer Aided Simulation and Numerical Descriptive Inherent Safety Technique (NuDIST)

Antonio Zuorro, Daylisney Cassiani-Cassiani, Demmy A. Meza-González, Kariana Andrea Moreno-Sader, Ángel Darío González-Delgado

Subject: Engineering, Bioengineering Keywords: Chitosan; Process safety; NuDIST; CAPE; Shrimp

Online: 9 July 2020 (07:49:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201911.0309.v1

A Fully Integrated in vitro Diagnostic Microsystem for Pathogen Detection Developed Using a “3D Extensible” Microfluidic Design Paradigm

Zhi Geng, Yin Gu, Shanglin Li, Baobao Lin, Peng Liu

Subject: Engineering, Bioengineering Keywords: in vitro diagnostics; microfluidics; full integration; lab-on-a-chip; pathogen detection

Online: 26 November 2019 (09:56:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.1992.v1

ChatGPT-Enabled daVinci Surgical Robot Prototype: Advancements and Limitations

Abhilash Pandya

Subject: Engineering, Bioengineering Keywords: Surgical Robotics; Natural Language Processing; ChatGPT

Online: 29 May 2023 (07:46:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0652.v1

An Approach Towards Motion-Tolerant PPG-Based Algorithm for Real-Time Heart Rate Monitoring of Moving Pigs

Ali Youssef, Alberto Peña Fernández, Laura Wassermann, Svenja Biernot, Eva-Maria Wittauer, Andre Bleich, Joerg Hartung, Daniel Berckmans, Tomas Norton

Subject: Engineering, Bioengineering Keywords: Pig’s Heart Rate; Photoplethysmography (PPG); Continuous Wavelet Transform (CWT); Motion Artefacts

Online: 26 July 2020 (17:58:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202302.0037.v1

From Observational to Actionable: Rethinking Omics in Biologics Production

Helen O. Masson, Karen Julie la Cour Karottki, Jasmine Tat, Hooman Hefzi, Nathan E. Lewis

Subject: Engineering, Bioengineering Keywords: biopharmaceutical protein production; cell line development; bioprocess optimization; omics; statistical inference; mechanistic models

Online: 2 February 2023 (08:45:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202304.0575.v3

Imagined Speech Classification Using EEG and Deep Learning

Mokhles M. Abdulghani, Wilbur L. Walters, And Khalid H. Abed

Subject: Engineering, Bioengineering Keywords: Inner Speech; Imagined Speech; EEG Decoding; Brain-Computer Interface; BCI; LSTM; Wavelet Scattering Transformation; WST.

Online: 15 May 2023 (05:43:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0651.v1

Non-Invasive PPG-Based System for Continuous Heart Rate Monitoring of Incubated Avian Embryo

Ali Youssef, Daniel Berckmans, Tomas Norton

Subject: Engineering, Bioengineering Keywords: Embryonic Heart Rate; Photoplethysmography (PPG); Continuous Wavelet Transform (CWT); Spectral Entropy

Online: 26 July 2020 (17:50:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0575.v1

Inner Speech Classification Using EEG and Deep Learning

Mokhles M. Abdulghani, Wilbur L. Walters, And Khalid H. Abed

Subject: Engineering, Bioengineering Keywords: Inner Speech; Imagined Speech; EEG Decoding; Brain-Computer Interface; BCI; LSTM; Wavelet Scattering Transformation; WST.

Online: 19 April 2023 (08:45:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0386.v1

Novel Hollow Fiber Membranes of PCL and PCL/Graphene as Scaffolds with Potential to Develop in vitro Blood-brain Barrier Models

Marián Mantecón-Oria, Nazely Diban, Maria T. Berciano, Maria J. Rivero, Oana David, Miguel Lafarga, Olga Tapia, Ane Urtiaga

Subject: Engineering, Bioengineering Keywords: mixed-matrix hollow fibers; graphene; poly(ε-caprolactone); 3D cell cultures; in vitro blood brain barrier (BBB) model

Online: 17 July 2020 (15:05:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0176.v1

An Innovative Low-Cost Equipment for Electro-Concentration of Microalgal Biomass

Edwar M. Sanchez-Galvis, Ingri Y. Cardenas-Gutierrez, Jefferson E. Contreras-Ropero, Janet B. García-Martínez, Andrés F. Barajas-Solano, Antonio Zuorro

Subject: Engineering, Bioengineering Keywords: dewatering; response surface methodology; Arduino; aluminum electrodes; microalgae harvesting

Online: 9 July 2020 (07:46:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0107.v1

From Shallow to Deep Bioprocess Hybrid Modeling: Advances and Future Perspectives

Roshanak Agharafeie, João Rodrigues Correia Ramos, Jorge M Mendes, Rui Oliveira

Subject: Engineering, Bioengineering Keywords: Artificial neural network; Deep learning; Hybrid model; Hybrid neural network; Bioprocess; Digitalization; Industry 4.0

Online: 4 October 2023 (06:52:01 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0461.v2

The Evolution of Cell Free Biomanufacturing

Michael Vilkhovoy, Abhinav Adhikari, Sandra Vadhin, Jeffrey Varner

Subject: Engineering, Bioengineering Keywords: cell free protein synthesis; cell free metabolic engineering; metabolic modeling

Online: 30 April 2020 (05:19:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0683.v1

Breaking New Ground: Exploring the Promising Role of Solid-State Fermentation in Harnessing Natural Biostimulants for Sustainable Agriculture

Roberto Carlos Solano Porras, Adriana Artola, Raquel Barrena, Golafarin Ghoreishi, Cindy Ballardo Matos, Antoni Sánchez

Subject: Engineering, Bioengineering Keywords: Natural biostimulant; Solid-state fermentation; Organic waste; Sustainable agriculture; crop improvement

Online: 9 June 2023 (09:46:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202311.0686.v1

Elasticity and Viscoelasticity Imaging Using Small Particles Exposed to an External Force

Hasan Koruk, Antonios N. Pouliopoulos

Subject: Engineering, Bioengineering Keywords: Elasticity imaging; elastography; bubble; sphere; interface; mathematical modelling; shear modulus; ultrasound sensors; viscosity; viscoelasticity imaging

Online: 10 November 2023 (07:37:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1529.v1

Brain Wearables: Validation Toolkit for Ear-Level EEG Sensors

Guilherme Correia, Michael J Crosse, Alejandro Lopez Valdes

Subject: Engineering, Bioengineering Keywords: Wearable Electroencephalography; Ear-EEG; Validation; Toolkit; EEG Phantom; Event-Related Potentials

Online: 20 December 2023 (10:23:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.0811.v1

Comprehensive Assessment of Biomass Properties for Energy Usage Using Near-infrared Spectroscopy and Spectral Multi-Preprocessing Techniques

Bijendra Shrestha, Jetsada Posom, Bim Prasad Shrestha, Panmanas Sirisomboon

Subject: Engineering, Bioengineering Keywords: Higher heating value; Ultimate analysis; Spectral multi-preprocessing method; Near-infrared spectroscopy; Partial least squares regression

Online: 12 June 2023 (09:27:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0589.v1

Study of Biaxial Mechanical Properties of the Passive Pig Heart: Material Characterisation and Categorisation of Regional Differences

Fulufhelo Nemavhola

Subject: Engineering, Bioengineering Keywords: Mechanical properties; constitutive modelling; cardiac mechanics; anisotropy; biaxial testing

Online: 24 September 2020 (18:24:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1474.v1

Deciphering Metabolic Pathways in High Seeding Density Fed-Batch Processes for Monoclonal Antibody Production: A Computational Modeling Perspective

Carolin Bokelmann, Alireza Ehsani, Jochen Schaub, Fabian Stiefel

Subject: Engineering, Bioengineering Keywords: intensified fed-batch; mathematical modelling; cellular metabolism; bioprocess optimization

Online: 26 February 2024 (15:35:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.0073.v1

Speckle Plethysmography and Photoplethysmography behaviour during Cold Pressor Test

Jorge Herranz Olazabal, Ilde Lorato, Jesse Kling, Marc Verhoeven, Fokko Wieringa, Chris Van Hoof, Willem Verkruijsse, Evelien Hermeling

Subject: Engineering, Bioengineering Keywords: speckle contrast; optical monitoring; laser speckle; SPG; PPG; CPT; hypoperfusion

Online: 2 May 2023 (08:25:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0838.v1

Smartphone- and Cloud-based Artificial Intelligence Quantitative Analysis System (SCAISY) for SARS-CoV-2-specific IgG Antibody Lateral Flow Assays

Samir Kumar, Taewoo Ko, Yeonghun Chae, Ahyeon Lee, Sanghoon Shin, Myung-Hyun Nam, Byung Soo Kim, Hyun Sik Jun, Sungkyu Seo

Subject: Engineering, Bioengineering Keywords: Smartphone; Point-of-care testing; Lateral flow assay; Artificial intelligence; SARS-CoV-2; IgG antibody

Online: 24 April 2023 (09:17:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0546.v1

Drug Diffusion inside the Tapered Hydrogel Microneedle: A Numerical Study

Hajar Moghadas, Navid Kashaninejad

Subject: Engineering, Bioengineering Keywords: Hydrogel Microneedle; Transdermal; Drug Delivery; Diffusion time; Numerical Simulation

Online: 31 March 2023 (09:31:25 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202306.0887.v1

A Semi – Three Dimensional (3D) Bioprinted Neurocardiac System for Tissue Engineering of a Cardiac Autonomic Nervous System (CANS) Model

Ivana Hernandez, Salma P. Ramirez, Wendy V. Salazar, Sarahi Mendivil, Andrea Guevara, Akshay Patel, Carla D Loyola, Zayra N. Dorado, Binata Joddar

Subject: Engineering, Bioengineering Keywords: 3D Bioprinting; neuro-cardiac junctions; 3D tissue model; Cardiomyocytes; Neuroblastoma cells

Online: 13 June 2023 (08:33:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0132.v1

Pelvic Ring Fractures: A Biomechanical Comparison of Sacral and Lumbopelvic Fixation Techniques

Sudharshan Tripathi, Norihiro Nishida, Sophia Soehnlen, Amey Kelkar, Yogesh Kumaran, Toshihiro Seki, Takashi Sakai, Vijay K. Goel

Subject: Engineering, Bioengineering Keywords: Pelvic ring fractures; fracture displacement; sacroiliac joint; fixation techniques; finite element analysis

Online: 2 February 2024 (07:27:56 CET)

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Abstract Background Context Pelvic ring fractures are becoming more common in the aging population and can prove to be fatal, having mortality rates between 10% and 16%. Stabilization of these fractures is challenging and often require immediate internal fixation. Therefore, it is necessary to have a biomechanical understanding of the different fixation techniques for pelvic ring fractures. Methods A previously validated three-dimensional finite element model of the lumbar spine, pelvis, and femur was used for this study. A unilateral pelvic ring fracture was simulated by resecting the left side of the sacrum and pelvis. Five different fixation techniques were used to stabilize the fracture. A compressive follower load and pure moment was applied to compare different biomechanical parameters including range of motion (contralateral sacroiliac joint, L1-S1 segment, L5-S1 segment), and stresses (L5-S1 nucleus stresses, instrument stresses) between different fixation techniques. Results Transiliac -trans sacral screw fixation at S1 and S2 showed the highest stabilization for horizontal and vertical displacement at the sacral fracture site and reduction of contralateral sacroiliac joint for bending and flexion range of motion by 165% and 121%, respectively. DTSF (Double transiliac rod and screw fixation) model showed highest stabilization in horizontal displacement at the pubic rami fracture site, while the L5_PF_W_CC (L5-Ilium posterior screw fixation with cross connectors) and L5_PF_WO_CC ( L5-Ilium posterior screw fixation without cross connectors) showed higher rod stresses, reduced L1-S1 (approximately 28%), and L5-S1 (approximately 90%) range of motion. Conclusions Longer sacral screw fixations were superior in stabilizing sacral and contralateral sacroiliac joint range of motion. Lumbopelvic fixations displayed a higher degree of stabilization in the horizontal displacement compared to vertical displacement of pubic rami fracture, while also indicating the highest rod stresses. When determining the surgical approach for pelvic ring fractures, patient-specific factors should be accounted for to weigh the advantages and disadvantages for each technique.

Preprint REVIEW | doi:10.20944/preprints202401.1148.v1

Application of Convolutional Neural Networks in Weed Detection and Identification: A Systematic Review.

Oscar Leonardo García-Navarrete, Adriana Correa-Guimaraes, Luis Manuel Navas-Gracia

Subject: Engineering, Bioengineering Keywords: Precision agriculture; weed classification; machine learning; machine vision; image processing; CNN.

Online: 16 January 2024 (00:36:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202303.0170.v1

Motor Imagery-Based Brain-Computer Interface with Dry Sensors and Multimodal Feedback: Towards Tele-Rehabilitation

Pasquale Arpaia, Damien Coyle, Antonio Esposito, Angela Natalizio, Marco Parvis, Marisa Pesola, Ersilia Vallefuoco

Subject: Engineering, Bioengineering Keywords: eletroencephalograhy; dry sensors; motor imagery; brain-computer interfaces; extended reality; telerehabilitation

Online: 9 March 2023 (09:20:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0401.v1

Space Bioprocess Engineering on the Horizon

Aaron Berliner, Isaac Lipsky, Davian Ho, Jacob Hilzinger, Gretchen Vengerova, George Makrygiorgos, Matthew McNulty, Kevin Yates, Nils Averesch, Charles Cockell, Tyler Wallentine, Lance Seefeldt, Craig Criddle, Somen Nandi, Karen McDonald, Amor Menezes, Adam Arkin

Subject: Engineering, Bioengineering Keywords: space systems bioengineering; biomanufacturing; space bioprocess engineering; biotransformation human exploration; in situ resource utilization; life support systems; biomanufacturing; space policy

Online: 24 December 2021 (10:59:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.0623.v1

Automatic Epileptic Seizure Prediction Based on Convolutional Neural Network and EEG Signal

Golamali Alizadeh, Tohidy Yousefi Rezaii, Saeed Meshgini

Subject: Engineering, Bioengineering Keywords: Epilepsy; Electroencephalogram; Convolutional neural networks; Brain signal integral; Brain signal derivative

Online: 8 June 2023 (10:13:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.0799.v1

Platelet Biorheology and Mechanobiology in Thrombosis: In Silico Perspectives

Rukiye Tuna, Wenjuan Yi, Esmeralda Crespo Cruz, JP Romero, Yi Ren, Jingjiao Guan, Yan Li, Yuefan Deng, Danny Bluestein, Z. Leonardo Liu, Jawaad Sheriff

Subject: Engineering, Bioengineering Keywords: von Willebrand factor; platelet margination; platelet adhesion; shear-induced platelet aggregation; platelet mechanobiology; biorheology; platelet activation; thrombosis

Online: 14 February 2024 (12:07:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0617.v1

Developing a New ANN Model to Estimate Daily Actual Evapotranspiration Using Limited Climatic Data and Remote Sensing Techniques

Halil Karahan, Mahmut Çetin, Müge Erkan Can, Omar Alsenjar

Subject: Engineering, Bioengineering Keywords: Evapotranspiration; artificial neural networks (ANNs); remote sensing (RS); NDVI; METRIC

Online: 12 February 2024 (09:43:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.0253.v1

Biomechanical Investigation of Red Cell Sedimentation Using Blood Shear Stress and Blood Flow Image in a Capillary Chip

Yang Jun Kang

Subject: Engineering, Bioengineering Keywords: Erythrocyte sedimentation rate (ESR); shear stress index; Aggregation index; Blood shear stress; Blood flow intensity; Capillary chip

Online: 5 July 2023 (08:55:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.0876.v1

Flexible Wearable Sensors for Respiration Monitoring: A Review

Tauseef Hussain, Sana Ullah, Raúl Fernández-García, Ignacio Gil

Subject: Engineering, Bioengineering Keywords: respiration sensors; breathing sensors; flexible sensors; wearable sensors

Online: 10 August 2023 (16:51:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0333.v1

Brain Inspired Spatio-Temporal Associative Memories for Neuroimaging Data: EEG and fMRI

Nikola K. Kasabov, Helena Bahrami, Maryam Doborjeh, Alan Wang

Subject: Engineering, Bioengineering Keywords: spatio-temporal associative memory; STAM; neuroimaging data; spiking neural networks; NeuCube; EEG; fMRI; neuroimage classification

Online: 3 August 2023 (10:46:24 CEST)

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