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Preprint ARTICLE | doi:10.20944/preprints201706.0132.v1

In Silico Screening and Analysis of Potential Inhibitors of Arylamine N-Acetyltransferases (NATs) from the Traditional Chinese Medicine: A Study Using Free Available Tools

Francisco Azevedo, Joveline Richardt, Mayrla Oliveira, Inês Araujo, Ricardo Oliveira, Luis Baptista, Hermes Amorim

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: arylamine N-acetyltransferases; cancer; tuberculosis; drug discovery; traditional Chinese medicine; virtual screening; molecular dynamics simulation; MM-PBSA

Online: 30 June 2017 (11:36:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202107.0614.v1

Mixed Effects and Mechanisms of Cannabinoids for Triple-Negative Breast Cancer Treatment

Khanh Tran

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Triple-negative breast cancer; cannabinoid; marijuana; cell signalling; medicinal plants

Online: 28 July 2021 (08:56:32 CEST)

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Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by the lack of estrogen receptors (ER), progesterone receptors, and HER-2 receptors. Thus, TNBC tumours do not benefit from the current therapies targeting ER or HER-2. Therefore, there is an urgent need to develop novel treatment for this subtype of breast cancer. Marijuana is a common name given to Cannabis plants, a group of plants in the Cannabis genus of the Cannabaceae family. Cannabis plants are among the oldest cultivated crops, traced back at least 12,000 years and are well known for their multi-purpose usage, including medicinal purposes. The main active compounds extracted from Cannabis plants are 21-carbon-containing terpenophenolics, which are referred to as phytocannabinoids. Of these, the tetrahydrocannabinol (THC) group contains highly potent cannabinoids, including delta-9-tetrahydrocannabinol (∆9-THC) and delta-8-tetrahydrocannabinol (∆8-THC), which are the most abundant THCs and are largely responsible for psychological and physiological effects of marijuana. The use of Cannabis plants for medicinal purposes was first recorded in 2337 BC in China, where Cannabis plants were used to treat pains, rheumatism, and gout. Recently, several cannabinoids have been approved for a number of treatments, one of which is the treatment of nausea and vomiting caused by chemotherapy in cancer patients. Furthermore, increasing evidence shows that cannabinoids not only attenuate side effects due to cancer treatment, but might also potentially possess direct antitumor effects in several cancer types, including breast cancer. However, anti-tumour activity of marijuana has been variable in different studies and even promoted tumour growth in some cases. In addition, the mechanisms of cannabinoid action in cancer remain unclear. This review summarizes evidence about the mixed actions of cannabinoids in cancer in general and triple-negative breast cancer in particular.

Preprint ARTICLE | doi:10.20944/preprints201705.0144.v1

Neuroprotective Effect of Anthocyanin Extract from Lycium ruthenicum Murray in Aβ1–42-induced Rat Model of AD

Xueling Wu, Xiaoxiao Li, Shuang Liang, Yanxia Liu, Xueling Dai, Qiusheng Zheng, Yaxuan Sun

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Alzheimer’s disease (AD); amyloid-β1-42(Aβ1–42); Lycium ruthenicum Murray (LRA); neuroprotective effect

Online: 19 May 2017 (06:26:45 CEST)

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Preprint REVIEW | doi:10.20944/preprints201904.0027.v2

The Pipeline of Processing fMRI Data with Python Based on the Ecosystem NeuroDebian

Qiang Li, Rong Xue

Subject: Computer Science And Mathematics, Analysis Keywords: neuroscience; big data; functional Magnetic Resonance (fMRI); pipeline; one platform system

Online: 8 April 2019 (05:46:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202012.0250.v1

Intestinal Absorption of β-Glucans and Their Effect on the Immune System

Shingo Hino, Naomichi Nishimura, Tsukasa Matsuda, Tatsuya Morita

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: β-glucan; intestinal absorption; immune system

Online: 10 December 2020 (11:30:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0139.v1

A Kinematic Model to Compensate the Structural Deformations in Machine Tools Using Fibre Bragg Grating (FBG) Sensors

Francesco Aggogeri, Alberto Borboni, Rodolfo Faglia, Angelo Merlo, Nicola Pellegrini

Subject: Engineering, Mechanical Engineering Keywords: kinematic model; fiber Bragg grating; deformations; machine tools calibration; predicted model; multiple regression analysis; finite element analysis

Online: 29 December 2016 (07:39:26 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0333.v1

Visiting Bitter Gourd (Momordica charantia) from a Breeding Perspective: A Review

Hari Kesh, Prashant Kaushik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: bitter gourd; breeding; genetic diversity; genomics; heterosis; molecular breeding; mutation breeding

Online: 19 April 2020 (06:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0002.v1

Simple Metal and Binary Alloy Phases Based on the fcc Structure: Electronic Origin of Distortions, Superlattices and Vacancies

Valentina F. Degtyareva, Nataliya S. Afonikova

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: crystal structure; Hume-Rothery phases; structure stability

Online: 2 January 2017 (10:42:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0445.v1

Financial Inclusion, Saving and Borrowing Behaviors in the United Arab Emirates and the United States: A Comparative Analysis

Ibrahim Niankara, Riham Muqattash

Subject: Business, Economics And Management, Economics Keywords: borrowing; economic growth; financial inclusion; saving; UAE; USA

Online: 24 July 2018 (06:13:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202006.0284.v1

Factors Affecting SARS-CoV-2 (COVID-19) Pandemic, including Zoonotic, Human Transmission and Chain of Infection. Reducing Public Health Risk by Serum Antibody Testing, Avoiding Screening in Unhygienic Places and False PCR Reporting. A Scientific Review

Kamran Mahmood Ahmed Aziz, Abdullah Othman, Waleed Alqahtani, Sumaiya Azhar

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; RT-PCR; antibody; zoonotic; animal transmission; genomics; asymptomatic fraction; herd immunity

Online: 23 June 2020 (13:30:11 CEST)

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Since December 2019, a rapid increase in the number of SARS-CoV-2 (COVID-19) cases was reported worldwide, despite strict infection control and lock down measures. Current paper investigated the actual facts behind this rapid increase in the number of cases. Study of genomic sequence reveals that domestic and wild animals were likely ancestors and zoonotic source for SARS-CoVs, MERS-CoVs, and SARS-CoV-2. Strong evidence suggest that these viruses already existed and replicated in animals and humans during past several decades, exhibiting diverse mutations, evolutions and self-limiting diseases, except during outbreaks. Serious zoonotic reservoir investigations are required to investigate animal transmission of SARS-CoVs and SARS-CoV-2 to limit current pandemic. This might be the reason of increasing number of cases via animals. SARS-CoV-2 has been retrospectively isolated in different studies in August 2019, several months before Wuhan announced. Hence, there is a possibility that viruses existed, went undetected, infecting subclinically, in past several years, and SARS-CoV-2 antigens and neutralizing antibodies may have been present in humans since long time. This might be another reason of increasing number of cases by screening as mass screening and antigen or antibody testing was not carried out in the past years. Randomized controlled trials are required to investigate human to human transmission by touch, as the current evidence is limited with conflicting results. As all SARS-CoVs are basically respiratory viruses, droplet precautions and infection control measures are essential, especially for hospital staff. Increased number of SARS-CoV-2 asymptomatic, or subclinical cases are detected worldwide. This silent phase of transmission can be beneficial for humans. Lack of symptoms eventually lessen virus transmission and reduce the pathogen's long-term survival and provide humoral herd immunity up to several years. Hence, seropositivity with diverse antibodies develops against mutating SARS-CoVs which will confer strong immunity during epidemics. Strategies such as identification, contact tracing and quarantine are costly and practically difficult. Hence, asymptomatic persons can continue their work with droplet precautions and standard infection control procedures, while symptomatic or sick persons can isolate themselves in their homes without the need for strict quarantine until clinical recovery, with reduced hospital visits and minimizing chances of hospital acquired infections. RT-PCR has low sensitivity and specificity, carries a high risk of handling live virus antigens, and requires difficult protocols. As viral load also sharply declines after few days of onset of infection, this technique might overlook infection. Furthermore, SARS-CoV-2 infection may be present in blood when oropharyngeal swabs are negative by RT-PCR. Additionally, RT-PCR usually gives false negative and false positive results and must be interpreted cautiously. This might be again a reason of increasing number of cases by false positive RT-PCR reporting. Moreover, antibodies against SARS-CoVs develop robustly in serum even by reduced amount of antigens. In contrast to RT-PCR, ELISA for diagnosing antibodies against SARS-CoV-2 demonstrates 100% specificity and 100% sensitivity, even in clinically asymptomatic individuals. These antibodies can be used for serologic surveys, monitoring and screening. However, screening tests for SARS-COV-2 should be avoided in unhygienic public places by nasopharyngeal swabs, which carry a high risk of further transmission, co-infection or superinfection. Such highly infectious virus must be isolated and tested in highly sterilized laboratory. Further strict international laws and policies are required to stop the possible spread of experimental viruses, biological warfare and bioterrorism.

Preprint ARTICLE | doi:10.20944/preprints201906.0071.v1

A Standardized Nomenclature and Atlas of the Male Terminalia of Drosophila melanogaster

Gavin Rice, Jean David, Yoshitaka Kamimura, John Masly, Alistair Mcgregor, Olga Nagy, Stéphane Noselli, Maria Daniela Santos Nunes, Patrick O'Grady, Ernesto Sánchez-Herrero, Mark Siegal, Masanori Toda, Mark Rebeiz, Virginie Courtier-Orgogozo, Amir Yassin

Subject: Biology And Life Sciences, Insect Science Keywords: genitalia; terminalia; anatomy; Drosophila melanogaster; nomenclature

Online: 10 June 2019 (08:55:53 CEST)

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Working Paper ARTICLE

Rethinking the Foundation of Physics and its Relation to Quantum Gravity and Quantum Probabilities: Unification of Gravity and Quantum Mechanics

Espen Haug

Subject: Physical Sciences, Acoustics Keywords: quantum mechanics; quantum probability; de Broglie wavelength; Compton wavelength; gravity; quantum gravity

Online: 24 December 2020 (11:45:05 CET)

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In this paper we will show that standard physics to a large degree consists of derivatives of a deeper reality. This means standard physics is both overly complex and also incomplete. Modern physics has typically started from working with first understanding the surface of the world, that is typically the macroscopic world, and then forming theories about the atomic and subatomic world. And we did not have much of a choice, as the subatomic world is very hard to observe directly, if not impossible to observe directly at the deepest level. Despite the enormous success of modern physics, it is therefore no big surprise that we at some point have possibly taken a step in the wrong direction. We will claim that one such step came when one thought that the de Broglie wavelength represented a real matter wavelength. We will claim that the Compton wavelength is the real matter wavelength. Based on such a view we will see that many equations in modern physics are only derivatives of much simpler relations. Second, we will claim that in today’s physics one uses two different mass definitions, one mass definition that is complete or at least more complete, embedded in gravity equations without being aware of it, as it is concealed in GM, and the standard, but incomplete, kg mass definition in non-gravitational physics. First, when this is understood, and one uses the more complete mass definition that is embedded in gravity physics, not only in gravity physics, but in all of physics, then one has a chance to unify gravity and quantum mechanics. Our new theory shows that most physical phenomena when observed over a very short timescale are probabilistic for masses smaller than a Planck mass and dominated by determinism at or above Planck mass size. Our findings have many implications. For example, we show that the Heisenberg uncertainty principle is rooted in a foundation not valid for rest-mass particles, so the Heisenberg uncertainty principle can say nothing about rest-masses. When re-formulated based on a foundation compatible with a new momentum that is also compatible with rest-masses, we obtain a re-defined Heisenberg principle that seems to become a certainty principle in the special case of a Planck mass particle. Furthermore, we show that the Planck mass particle is linked to gravity and that we can easily detect the Planck scale from gravity observations. The Planck mass particle is unique as it only lasts the Planck time, and in that very short time period it can only be observed directly from itself, and it therefore closely linked to absolute rest.

Preprint ARTICLE | doi:10.20944/preprints201612.0078.v1

An Overview and Evaluation of Recent Machine Learning Imputation Methods Using Cardiac Imaging Data

Yuzhe Liu, Vanathi Gopalakrishnan

Subject: Computer Science And Mathematics, Computer Science Keywords: missing value imputation; machine learning; decision tree imputation; k-nearest neighbors imputation; self-organizing map imputation

Online: 15 December 2016 (08:27:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0146.v1

Numerical Analysis of Unsymmetric Flatbak Trailing Edge Airfoil to Reduce Turbomachinery Noise in Power Generation Cycle

Hyungki Shin, Hogeon Kim, Taehyung Kim, Soo-Hyun Kim, Soogab Lee, Young-Jin Baik, Gilbong Lee

Subject: Engineering, Marine Engineering Keywords: power generation cycle; turbo machinery; turbine; compressor; blade; airfoil; noise

Online: 19 May 2017 (08:54:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0092.v1

COVID-19 Vaccine Candidates by Identification of B and T Cell Multi-Epitopes Against SARS-COV-2

Suresh Kumar, Sarmilah Mathavan, Wee Jia Jin, Nur Azznira Bt Azman, Devindren Subramanaiam, Nur Afiqah Binti Zainalabidin, Dhivashini Lingadaran, Zainah Binti Abdul Sattar, Danniya Lakshmi Manickam, Priscilla Sheba Anbananthan, Johan Ahmad Taqiyuddin, Yuvapriya Thevarajan

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: COVID-19; SARS-CoV-2; epitopes; B-cell; T-cell; immuno informatics; MHC-I; MHC-II

Online: 4 August 2020 (11:18:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0012.v1

Thermodynamics of a Set of Closed Curved Surfaces and Noether’s Theorem

Harmen Hollestelle

Subject: Physical Sciences, Thermodynamics Keywords: thermodynamics; surfaces; curvature

Online: 3 January 2017 (10:21:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0002.v1

Iterated Economic Games, Logic Gates, and the Flow of Shared Information in Strategic Interactions

Michael Harré

Subject: Business, Economics And Management, Economics Keywords: information theory; transfer entropy; game theory; logic gates; multilayer perceptrons; strategic behaviour; decision theory

Online: 1 March 2017 (09:26:28 CET)

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Preprint ARTICLE | doi:10.3390/sci2040077

Atmospheric Temperature and CO<sub>2</sub>: Hen-or-Egg Causality?

Demetris Koutsoyiannis, Zbigniew Kundzewicz

Subject: Environmental And Earth Sciences, Environmental Science Keywords: temperature; global warming; greenhouse gases; atmospheric CO₂ concentration

Online: 20 October 2020 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0042.v1

A Wide-FoV Athermalized Infrared Imaging System with a Two-Piece Lens

Bin Feng, Zelin Shi, Yaohong Zhao, Haizheng Liu, Li Liu

Subject: Physical Sciences, Optics And Photonics Keywords: infrared imaging; wide field of view; athermalization; two-piece lens

Online: 8 March 2017 (04:40:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0057.v2

Global Existence, Asymptotic Behavior and Blow-up of Solutions for a Suspension Bridge Equation with Nonlinear Damping and Source Terms

Wenjun Liu, Hefeng Zhuang

Subject: Computer Science And Mathematics, Analysis Keywords: suspension bridges; fourth order wave equation; nonlinear damping; source term; existence; blow up

Online: 24 February 2017 (09:06:57 CET)

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Preprint REVIEW | doi:10.20944/preprints202102.0108.v1

Machine Learning and Deep Learning for Sentiment Analysis Over Students' Reviews: An Overview Study

Ru Yang

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Sentiment Analysis; Students' feedback; Students' reviews; Natural language processing; Data mining; Deep learning; Machine learning

Online: 3 February 2021 (10:11:54 CET)

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Preprint REVIEW | doi:10.20944/preprints201705.0021.v1

Traceability on Machine Tool Metrology: A Review

Unai Mutilba, Eneko Gomez-Acedo, Gorka Kortaberria, Aitor Olarra, José Antonio Yagüe-Fabra

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: machine tool metrology; temperature; uncertainty; traceability; error sources

Online: 2 May 2017 (04:35:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0138.v1

On Unsteady Three-Dimensional Axisymmetric MHD Nanofluid Flow with Entropy Generation and Thermo-Diffusion Effects

Mohammed Almakki, Sharadia Dey, Sabyasachi Mondal, Precious Sibanda

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Unsteady 3-D axisymmetric nanofluid; Entropy generation; Spectral quasi-linearization method.

Online: 17 March 2017 (15:10:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0065.v3

The Consequences of Corruption on Economic Growth in Mediterranean Countries: Evidence from Panel Data Analysis

Hicham Boussalham

Subject: Business, Economics And Management, Economics Keywords: Corruption; Economic growth; Panel Data

Online: 26 February 2018 (15:38:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0085.v1

Identification of Drought-Responsive microRNAs from Roots and Leaves of Alfalfa by High-Throughput Sequencing

Yue Li, Liqiang Wan, Shuyi Bi, Xiufu Wan, Zhenyi Li, Jing Cao, Zongyong Tong, Hongyu Xu, Feng He, Xianglin Li

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: alfalfa; drought; microRNA; small RNA; differential expression

Online: 23 February 2017 (09:50:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0170.v1

A Method to Count Olive Trees in Heterogenous Plantations from Aerial Photographs

Yann H. Chemin, Pieter S.A. Beck

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: tree counting, olive trees, Xylella fastidiosa, Puglia, Italy, algorithms, image processing

Online: 27 October 2017 (12:30:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints201707.0062.v1

The Central Role of Chemistry in the Transition to the Solar Economy

Mario Pagliaro

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: sol-gel; solar energy; bioeconomy; catalysis; nanochemistry

Online: 21 July 2017 (11:30:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0183.v1

Lempel-Ziv Complexity of Photonic Quasicrystals

Juan J. Monzon, Angel Felipe, Luis L. Sanchez-Soto

Subject: Physical Sciences, Optics And Photonics Keywords: quasicrystals; photonic crystals; photonic bandgap materials

Online: 28 April 2017 (04:57:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0102.v1

Experimental Studies of Turbulence Intensity around a Tidal Turbine Support Structure

Stuart Walker, Lorenzo Cappietti

Subject: Engineering, Energy And Fuel Technology Keywords: Marine Energy; Tidal turbine; horizontal-axis marine current turbine; OCT; Turbulence; Support Structure; device wake

Online: 28 February 2017 (11:55:00 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202007.0569.v1

Can Ventilatory Strategies in COVID-19 Have an Impact on Outcomes?

Peter Sherren, Luigi Camporota, Barnaby Sanderson, Andrew Jones, Manu Shankar-Hari, Chris Meadows, Nicholas Barrett, Marlies Ostermann, Nicholas Hart

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: SARS-CoV-2; COVID-19; respiratory failure; ARDS; ventilation; ECMO

Online: 24 July 2020 (04:44:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints201705.0200.v1

The Thailand Declaration of the International College of Nutrition; Can Functional Foods and Functional Crops Decrease the Risk of Chronic Diseases and Provide Wellness?

Wiriya Phomkong, Ekasit Onsaard, Dherapol Bansiddhi, Ram B. Singh, Buncha Ooraikul, Arunporn Itharat, Fabien De Meester, Jagdish P. Sharma, Rana G. Singh, Usha Singh, Harpal S. Buttar, Istvan G. Telessy, Toru Takahashi, Lech Ozimek, Jae-Kwan Hwang, Kohei Oda, Douglas W. Wilson

Subject: Chemistry And Materials Science, Food Chemistry Keywords: Diet: Functional foods: Western foods: Mediterranean foods: Feeding, Plant breeding

Online: 29 May 2017 (17:38:59 CEST)

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There is evidence that optimal nutrition is fundamental to human health and in the prevention of non-communicable diseases (NCDs) later in adult life. The identification, production and consumption of functional foods worldwide can increase health benefits for all who can access and afford such foods subject to advice from nutritionists. Recent meetings organized by the health agencies, give a crucial opportunity to make nutrition, a central part of the post-2015 sustainable human and agricultural development agenda. The aim of discussions in these meetings was to provide functional crops and foods to achieve optimal health by prevention of NCDs. It is possible that these efforts might ensure that the goals and targets set in the agenda are adequate to address the many challenges of global undernutrition as well as obesity which are major risk factors of NCDs. In many developing and middle income countries, food security provided by the governments, in one sense understandably, gave least consideration to functional foods supply and the prevention of obesity and metabolic syndrome, resulting in to emergence of NCDs. The Thailand Declaration reiterates that commitments to eradicate hunger and undernutrition as well as over-nutrition, and to increase investments in effective interventions; designers foods and designers crops. However, in planning coherent policies, our past experience on rapidly absorbed, energy-rich processed foods should be taken in to account while developing sustainable food systems. The food industry should be educated to exploit the expertise of food scientists and health professionals in designing functional foods taking cognizance of manufacturing and processing. Similarly, agriculture scientists may be actively involved in educating farmers so as to grow cash crops providing functional foods. The aim should be to achieve an increase in the availability of functional foods to an extent, or by a policy, by which such foods are available to poors, at affordable cost to prevent hunger and undernutrition and related diseases as well as NCDs. In addition our efforts might help in developing an international consensus on how to approach the development of new designer foods by farmers and food industry to produce low glycemic index foods. Such efforts may establish an international framework for the prevention of NCDs, so that human susceptibility to these diseases is substantially diminished.

Preprint REVIEW | doi:10.20944/preprints201908.0203.v1

Advances in Machine Learning Modeling Reviewing Hybrid and Ensemble Methods

Sina Ardabili, Amir Mosavi, Annamária R. Várkonyi-Kóczy

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; deep learning; ensemble models

Online: 20 August 2019 (08:41:28 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201612.0043.v1

Application of German Climate Change Adaptation Strategy for Federal State of Saxony-Anhalt, Germany

Eklavyya Popat, Falk Böttcher

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: climate change; climatic water balance; irrigation; natural snow cover; the DAS indicator project; Saxony-Anhalt; soil moisture content

Online: 7 December 2016 (11:30:40 CET)

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Preprint ARTICLE | doi:10.3390/sci2010007

Static and Dynamic Evaluation of an UWB Localization System for Industrial Applications

Mickaël Delamare, Remi Boutteau, Xavier Savatier, Nicolas Iriart

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: indoor localization; Ultra WideBand (UWB); range estimation

Online: 29 February 2020 (00:00:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0068.v1

Estimation of Particulate Matter Impact on Human Health within the Urban Environment of Athens City, Greece

Konstantinos P. Moustris, Kleopatra Ntourou, Panagiotis Nastos

Subject: Environmental And Earth Sciences, Environmental Science Keywords: particulate matter; AirQ model; hospital admission respiratory disease; Athens; Greece

Online: 14 November 2016 (04:13:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202006.0024.v1

Non-Synonymous Mutation Analysis in SARS-CoV-2 Variants Isolated from Humans and Prediction of Conserved Linear Antibody Epitopes for Use in Country-wise Epitope-Based Vaccine Development

Pankaj Kumar, Kunal Sharma, Naima Noor Khan, Hamza Bin Sana, Mohammad Ali Khan

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; Mutations; Epitope; Vaccine

Online: 4 June 2020 (05:50:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints201908.0316.v1

Airborne Microplastics: A Review Study on Method for Analysis, Occurrence, Movement and Risks

Enyoh Christian Ebere, Verla Andrew Wirnkor, Verla Evelyn Ngozi, Ibe Francis Chizoruo, Amaobi Collins Emeka

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: air pollution; dermal route; fibers; health risk; inhalation; micropollutants

Online: 30 August 2019 (05:08:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0164.v2

Toward a More Complete, Flexible, and Safer Speed Planning for Autonomous Driving via Convex Optimization

Yu Zhang, Huiyan Chen, Steven L. Waslander, Tian Yang, Sheng Zhang, Guangming Xiong, Kai Liu

Subject: Engineering, Mechanical Engineering Keywords: speed planning; convex optimisation; autonomous driving; friction circle; driving safety; dynamic obstacle avoidance; ride comfort; mobility

Online: 16 May 2018 (11:08:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0116.v1

Impact of a Warming Climate on Hydropower in the Northeast United States: The Untapped Potential of Non-Powered Dams

Nima Ehsani, Charles J. Vörösmarty, Balázs M. Fekete, Eugene Z. Stakhiv

Subject: Environmental And Earth Sciences, Environmental Science Keywords: hydropower; climate change; renewable energy; dams

Online: 19 November 2017 (05:29:52 CET)

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Preprint REVIEW | doi:10.20944/preprints202103.0316.v1

Life Cycle Assessment and Life Cycle Cost Analysis in Infrastructure Projects: A Systematic Review

Wesam Salah Alaloul, Muhammad Altaf, Muhammad Ali Musarat, Muhammad Faisal Javed, Amir Mosavi

Subject: Engineering, Civil Engineering Keywords: Infrastructure projects; LCCA; Systematic Review; PRISMA statement; Sustainability; LCA

Online: 11 March 2021 (11:23:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0047.v1

The Influence of Tool Texture on Friction and Lubrication in Strip Reduction Testing

Mohd Hafis Sulaiman, Peter Christiansen, Niels Bay

Subject: Engineering, Mechanical Engineering Keywords: tool surface texture; lubricant entrapment; strip drawing test

Online: 8 December 2016 (10:09:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0015.v1

Electromagnetic Performances Evaluation of an Outer-Rotor Flux-Switching Permanent Magnet Motor Based on Electrical-Thermal Two-Way Coupling Method

Zhengming Shu, Xiaoyong Zhu, Li Quan, Yi Du, Chang Liu

Subject: Physical Sciences, Particle And Field Physics Keywords: electrical-thermal two-way coupling; flux-switching permanent magnet motor; thermal analysis; permanent magnet material characteristics

Online: 4 April 2017 (08:38:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1271.v1

Exploring Ethical Boundaries: Can ChatGPT Be Prompted to Give Advice on How to Cheat in University Assignments?

Dirk H.R. Spennemann

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: academic misconduct; artificial intelligence; ChatGPT; ethics; language model; machine learning

Online: 17 August 2023 (10:32:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0126.v1

IQGAP1 in Podosome /Invadosome is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status

Deborah Rotoli, Natalia Pérez-Rodríguez, Manuel Morales, María Del Carmen Maeso, Julio Ávila, Ali Mobasheri, Pablo Martín-Vasallo

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: IQGAP1; GBM; scaffold protein; podosome/invadosome

Online: 24 November 2016 (18:02:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints201706.0090.v1

Existence results of solutions for some fractional neutral functional integro-differential equations with infinite delay

Kazem Nouri, Marjan Nazari, Bagher Keramati

Subject: Computer Science And Mathematics, Mathematics Keywords: fractional neutral integro-differential equations; initial value problem; Caputo fractional derivative; Krasnoselskii's fixed point theorem

Online: 20 June 2017 (03:42:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0072.v1

The Dynamics of the Wave Packet in the Majorana Equation

Luca Nanni

Subject: Physical Sciences, Particle And Field Physics Keywords: wave packet; infinite components wavefunctions; Zitterbewegung

Online: 16 January 2017 (04:03:31 CET)

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Preprint REVIEW | doi:10.20944/preprints202006.0232.v1

Repurposing of FDA Approved Drugs as COVID-19 Therapeutics: Safety Concerns and Contraindications of Drugs in Clinical Trials

Ravinder Naik Dharavath, Meenu Dutt, Sunil Kumar, Priya Badyal, Nitin Rawat, Tanzeer Kaur, Shweta Sharma, Mahendra Bishnoi, Kanwaljit Chopra

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Adverse drug reactions; Anti-COVID drugs; Coronavirus; Drug repurposing; Drug toxicity; Pharmacotherapy

Online: 18 June 2020 (12:43:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0157.v1

A CNN-Based Fusion Method for Feature Extraction from Sentinel Data

Giuseppe Scarpa, Massimiliano Gargiulo, Antonio Mazza, Raffaele Gaetano

Subject: Engineering, Electrical And Electronic Engineering Keywords: Coregistration; pansharpening; multi-sensor fusion; multitemporal images; deep learning; normalized difference vegetation index (NDVI)

Online: 21 December 2017 (17:10:23 CET)

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Preprint REVIEW | doi:10.20944/preprints201705.0052.v1

Progress in Research of Flexible MEMS Microelectrodes for Neural Interface

Long-Jun Tang, Hong-Chang Tian, Xiao-Yang Kang, Wen Hong, Jing-Quan Liu

Subject: Engineering, Electrical And Electronic Engineering Keywords: MEMS; microelectrodes; neural interface; conducting polymer; nanotechnology

Online: 8 May 2017 (08:39:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0331.v1

Determining Symptomatic Factors of Nomophobia in Peruvian Students from the National University of Engineering

Jimmy Aurelio Rosales-Huamani, Rita Rocio Guzman-Lopez, Eder Eliseo Aroni-Vilca, Carmen Rosalia Matos-Avalos, Jose Luis Castillo-Sequera

Subject: Social Sciences, Behavior Sciences Keywords: nomophobia; anxiety; phobia; panic.

Online: 31 January 2019 (16:01:30 CET)

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Preprint REVIEW | doi:10.20944/preprints201902.0015.v1

Scoping Review of the Person-Centered Literature in Adult Physical Rehabilitation

Tiago Jesus, Felicity AS Bright, Cátia S Pinho, Christina Papadimitriou, Nicola M Kayes, Cheryl A Cott

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Rehabilitation; Review; Patient-Centered Care

Online: 1 February 2019 (10:53:15 CET)

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Objective: To map the literature pertaining to adult Person-Centered Rehabilitation (PCR).Data Sources: Following our previously published scoping review protocol, data were identified through: three major databases, snowball searches and expert consultation.Study Selection: Two independent reviewers identified English-language papers which addressed adult physical rehabilitation and met one or more of the six pre-defined inclusion categories for PCR content. Data Extraction: Two independent reviewers extracted key characteristics of included papers (e.g. aims, methods, participants). Quantitative methods (descriptive statistics, regression analysis) and qualitative content analyses were used to synthesize the results. Data synthesis: Of 5084 unique records initially screened, 145 papers were included: 111 empirical, including 11 systematic reviews. Empirical papers had data from 13498 clients and 3849 providers, in total. Yearly publications grew exponentially from 2000 to 2017 (r²= 0.65; p<0.01). Publications were unevenly distributed by countries (e.g. United States’ publications per population size was 45 times lower than New Zealand’s). Most papers focused in more than one profession, setting-type or health conditions, respectively 57.2%, 66.2%, and 60.7%. Finally, more than half of the empirical papers (53.2%) studied implementation of PCR approaches, including its effect. Conclusion: This scoping review synthesizes key characteristics and publication trends in the PCR literature, which is mainly empirical and growing exponentially over time. Stakeholders can use the identified trends, gaps, and literature map to guide further PCR research, and both clinical and organizational practices. The high prevalence of papers focused on multiple professions, settings-type, or health conditions reinforces the need for developing a transdisciplinary, trans-service model of PCR, which will be derived from a thematic analysis of this body of literature.

Preprint REVIEW | doi:10.20944/preprints201909.0098.v1

Methods for Studying Endoplasmic Reticulum Stress

Daniela Correia da Silva, Patricia Valentao, Paula Andrade, David Pereira

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: unfolded protein response; endoplasmic reticulum; PERK; IRE-1; ATF4

Online: 9 September 2019 (11:54:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0065.v1

Backtesting the Lee-Carter and the Cairns-Blake-Dowd Stochastic Mortality Models on Italian Death Rates

Carlo Maccheroni, Samuel Nocito

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: lee-carter; cairns-blake-dowd; mortality models; backtesting

Online: 13 January 2017 (01:56:49 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints201912.0291.v1

Night Matters – Why the Interdisciplinary Field of “Night Studies” is Needed

Christopher C.M. Kyba, Sara B. Pritchard, A. Roger Ekirch, Adam Eldridge, Andreas Jechow, Christine Preiser, Dieter Kunz, Dietrich Henckel, Franz Hölker, John Barentine, Jørgen Berge, Josiane Meier, Luc Gwiazdzinski, Manuel Spitschan, Mirik Milan, Susanne Bach, Sibylle Schroer, Will Straw

Subject: Social Sciences, Education Keywords: night; night science; night research; interdisciplinary research

Online: 22 December 2019 (02:25:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints201706.0007.v1

Pipeline Leak Detection by Transient-Based Method Using MATLAB® Functions

Albert Carbó-Bech, Salvador A. De Las Heras, Alfredo Guardo

Subject: Engineering, Mechanical Engineering Keywords: pipeline modeling; leak detection; transient-based method; pipeline system

Online: 1 June 2017 (08:20:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0004.v1

Surface Plasmon-Coupled Enhanced Transmission

Amir Djalalian-Assl

Subject: Physical Sciences, Optics And Photonics Keywords: SPCE; SPP; plasmonics; diamond; bullseye; radiative decay rate

Online: 2 January 2017 (11:07:29 CET)

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Preprint REVIEW | doi:10.20944/preprints201801.0218.v1

Biodegradable and Biocompatible Polyhydroxyalkanoates (PHA): Auspicious Microbial Macromolecules for Pharmaceutical and Therapeutic Applications

Martin Koller

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Biocompatibility; Biodegradability; Biopolyesters; Biopolymers; Composites; Drug Release; Implants; Polyhydroxyalkanoates; Scaffolds; Tissue Engineering

Online: 23 January 2018 (16:49:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.0195.v1

LLMs and AI: Understanding Its Reach and Impact

Anand Gokul

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: llm; impact; society; ai; large-language-model; transformer; natural language processing; nlp

Online: 4 May 2023 (05:15:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0019.v1

Influence of the Electrolyte Concentration on the Smooth TiO2 Anodic Coatings on Ti-6Al-4V

María Laura Vera, Ángeles Colaccio, Mario Roberto Rosenberger, Carlos Enrique Schvezov, Alicia Esther Ares

Subject: Chemistry And Materials Science, Biomaterials Keywords: anodic oxidation; titanium dioxide; electrolyte concentration; sulfuric acid

Online: 2 March 2017 (18:25:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0184.v1

Parametric Study of the Centrifugal Insurance Mechanism in MEMS Safety and Arming Device

Dakui Wang, Wenzhong Lou, Yue Feng, Fufu Wang

Subject: Engineering, Mechanical Engineering Keywords: MEMS S&A device; centrifugal insurance mechanism; nonlinear dynamic method; parametric study

Online: 24 March 2017 (10:04:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0064.v1

Identification of Secondary Phases in Cu₂ZnSnS₄ Layers by In-depth Resolved X-ray Photoelectron Spectroscopy Analysis

Xianfeng Zhang, M. Kobayashi

Subject: Chemistry And Materials Science, Other Keywords: secondary phases; CZTS film; XPS

Online: 12 January 2017 (11:04:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints201806.0044.v1

Interest in the Biosphere and Environmental Awareness and Optimism among Students: A Seemingly Unrelated Bivariate Weighted Ordered Probit Modeling with Country Fixed Effects

Ibrahim Niankara, Didier T. Zoungrana

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: air pollution; environmental awareness; environmental education; green gas emission; sustainable development; water shortage

Online: 4 June 2018 (13:01:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints201912.0152.v1

Is Amending Section 25 of the South African Constitution an End to the Land Reform Debate?

Joseph Lekunze, Usapfa Luvhengo

Subject: Social Sciences, Geography, Planning And Development Keywords: land expropriation; intra-racial tension; social cohesion; political and traditional elitism; marginalised landless majority

Online: 11 December 2019 (11:38:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0215.v1

Deadwood Density and Moisture Variation in a Natural Temperate Spruce-Fir-Beech Forest

Tomáš Přívětivý, Petr Baldrian, Pavel Šamonil, Tomáš Vrška

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: downed deadwood; decay stage; decomposition; wood density; wood moisture

Online: 30 May 2017 (09:04:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202102.0250.v1

Measuring Customer Service Experience in Offline and Online Retail Environments

Kuo-Ming Chu

Subject: Business, Economics And Management, Business And Management Keywords: Customer Service Experience; Multichannel Retailing; Customer Journeys; Customer Equity

Online: 10 February 2021 (10:25:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0120.v1

Active AU Based Patch Weighting for Facial Expression Recognition

Weicheng Xie, Linlin Shen, Meng Yang, Zhihui Lai

Subject: Computer Science And Mathematics, Computer Science Keywords: expression recognition; expression triplet; feature optimization; AU weighting; active AU detection.

Online: 26 January 2017 (08:52:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0129.v1

Process Heat Generation Potential from Solar Concentration Technologies in Latin America: The Case of Argentina

Isidoro Lillo, Elena Pérez, Sara Moreno, Manuel Silva

Subject: Engineering, Energy And Fuel Technology Keywords: feasibility; solar thermal energy; heat process; greenhouse gas emissions

Online: 17 March 2017 (04:05:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0207.v9

On Duality Principles and Related Convex Dual Formulations Suitable for Local Non-Convex Variational Optimization

Fabio Botelho

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: convex dual variational formulation; duality principle for non-convex local primal optimization; Ginzburg-Landau type equation

Online: 24 November 2022 (14:33:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0017.v1

Neutrosophic Modal Logic

Florentin Smarandache

Subject: Computer Science And Mathematics, Logic Keywords: neutrosophy; neutrosophic logic; neutrosophic alethic modalities; neutrosophic possibility; neutrosophic necessity; neutrosophic impossibility; neutrosophic temporal modalities; neutrosophic epistemic modalities; neutrosophic doxastic modalities; neutrosophic deontic modalities

Online: 5 February 2017 (09:41:31 CET)

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Preprint REVIEW | doi:10.20944/preprints201705.0209.v1

Influenza virus infection, interferon response, viral counter-response and apoptosis

Jung Min Shim, Jinhee Kim, Ji-Young Min, Denis E. Kainov

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: influenza virus; apoptosis; antiviral agent; innate immunity; host response

Online: 30 May 2017 (07:13:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0080.v1

Effect of Vermicompost Application on Soil and Growth of the Plant Sesamum indicum L.

Vasanth Pandiyan C, Balaji K, Sujatha Saravanan, Shylaja Gunasekaran, Gokul Raghavendra Srinivasan, Kiresee Saghana P R, Manivel G

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Vermicompost; Sesamum indicum L.; Perionyx excavates; NPK Fertilizers; Farm yard Manure; plant growth components

Online: 6 February 2020 (09:05:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0113.v1

Identification of Anthocyanins Compositions and Functional Analysis of An Anthocyanin Activator in Solanum nigrum Fruits

Shaoli Wang, Zhaohui Chu, Mingxing Ren, Ru Jia, Changbao Zhao, Dan Fei, Hao Su, Xiaoqi Fan, Xiaotian Zhang, Yang Li, Yingzi Wang, Xinhua Ding

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Solanum nigrum; anthocyanins purification; HPLC-MS/MS; antioxidant capacity; SnMYB

Online: 15 May 2017 (17:31:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0010.v1

Solar Radiation–The Estimation of the Optimum Tilt Angles for South-Facing Surfaces in Pristina

Xhevat Berisha, Arianit Zeqiri, Drilon Meha

Subject: Engineering, Mechanical Engineering Keywords: solar energy; gains; estimation; tilt angle; south-facing; surface; Pristina

Online: 3 August 2017 (10:51:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0162.v1

Retrieval of snow properties from the Sentinel-3 Ocean and Land Colour Instrument

Alexander Kokhanovsky, Maxim Lamare, Olaf Danne, Marie Dumont, Carsten Brockmann, Ghislain Picard, Laurtent Arnaud, Vincent Favier, Bruno Jourdain, Emmanuel Lemeur, Biagio Di Mauro, Teruo Aoki, Masashi Niwano, Vladinmir Rozanov, Sergey Korkin, Sepp Kipfstuhl, Johannes Freitag, Maria Hoerhold, Alexandra Zuh, Diana Vladimirova, Anne-Katrine Faber, Hans-Christian Steen-Larsen, Sonja Wahl, Jonas Andresen, Baptiste Vandecrux, Dirk van As, Kenneth Mankoff, Michael Kern, Eleonora Zege, Jason Box

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: snow characteristics; optical remote sensing; sow grain size; specific surface area; albedo; Sentinel 3, OLCI

Online: 17 June 2019 (10:48:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0107.v1

Compatibility and Stability of Daptomycin Lock Solutions in Combination with Gentamicin, Azithromycin, Heparin and Trisodium Citrate

P. Brandon Bookstaver, Padmavathy Premnath, Kayisa Wright, Campbell McInnes

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: daptomycin; antibiotic lock therapy; gentamicin; azithromycin; catheter-related bloodstream infections

Online: 10 September 2019 (10:43:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0114.v1

Optimal Design of Safety Instrumented Systems for Pressure Control of Methanol Separation Columns in the Bisphenol A Manufacturing Process

In-Bok Lee, Insung Woo

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: relief system; safety instrumented system; pressure relief valve; safety integrity level; minimize design capacity

Online: 23 December 2016 (10:12:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202105.0549.v1

What Could Explain the Lower COVID-19 Burden in Africa Despite Considerable Circulation of the SARS-CoV-2 Virus?

Richard G. Wamai, Jason L. Hirsch, Wim Van Damme, David Alnwick, Robert C. Bailey, Stephen Hodgins, Uzma Alam, Mamka Anyona

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19 pandemic; Africa; SARS-CoV-2 virus spread; lower COVID-19 disease burden; African populations; demographic pyramid; trained immunity; government measures

Online: 24 May 2021 (09:56:05 CEST)

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Preprint ARTICLE | doi:10.3390/sci1020034

Copper-to-Zinc Ratio Correlates with an Inflammatory Marker in Patients with Sickle Cell Disease

Mathias Emokpae, Emmanuel Fatimehin

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Copper; c-reactive protein; inflammation; sickle cell disease; zinc

Online: 4 July 2019 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0237.v1

Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Anti-Proliferation Effects in Hepatocellular Carcinoma Cells

Subbroto Kumar Saha, Yingfu Yin, Kyeongseok Kim, Gwang-Mo Yang, Ahmed Abdal Dayem, Hye Yeon Choi, Ssang-goo Cho

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: valproic acid; doxorubicin; reactive oxygen species; autophagy; cell death; caveolae endocytosis pathway

Online: 31 March 2017 (12:08:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0156.v1

Deep Reinforcement Learning for Energy Management in a Microgrid with Flexible Demand

Taha abd el halim Nakabi, Pekka Toivanen

Subject: Engineering, Energy And Fuel Technology Keywords: Artificial intelligence; Deep reinforcement learning; Demand Response; Dynamic pricing; Energy management system; Microgrid; Neural networks; Price-responsive loads; Smart grid; Thermostatically controlled loads

Online: 7 October 2020 (11:21:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0160.v1

Wireless Monitoring of Induction Machine Rotor Physical Variables

Jefferson Doolan Fernandes, Francisco Elvis Carvalho Souza, Glauco George Cipriano Maniçoba, Andres Ortiz Salazar, José Alvaro de Paiva

Subject: Engineering, Electrical And Electronic Engineering Keywords: wireless communication; energy harvesting; electrical machines maintenance; induction motor control systems; rotor temperature

Online: 25 April 2017 (16:12:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0131.v1

Ecological Structure of a Tropical Urban Forest in Bang Kachao Peninsula, Bangkok

Montathip Sommeechai, Chongrak Wachrinrat, Dell Bernard, Nipon Thangtam, Jamroon Srichaichana

Subject: Environmental And Earth Sciences, Environmental Science Keywords: LAI; NVDI; stand structure; urban forest; Thailand

Online: 20 November 2017 (16:52:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0044.v2

Dielectric Properties of Zinc Sulfide Concentrate during the Roasting at Microwave Frequencies

Guangjun He, Shiwei Li, Kun Yang, Jian Liu, Peng Liu, Libo Zhang, Jinhui Peng

Subject: Engineering, Energy And Fuel Technology Keywords: dielectric properties; microwave; zinc sulfide concentrate

Online: 14 February 2017 (07:45:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0020.v1

The Effects of Teleworking on Housework Division and Well-Being of Couples

Eleftherios Giovanis

Subject: Business, Economics And Management, Economics Keywords: Gender Roles; Household Production; Telecommuting; Teleworking; Well-Being

Online: 4 January 2017 (10:43:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202103.0523.v1

'Copper and Bronze in Art' and the Search for Rare Corrosion Products

Gerhard Eggert

Subject: Chemistry And Materials Science, Metals, Alloys And Metallurgy Keywords: basic copper(II) formate; ‘Black Spots’; chalconatronite; copper(II) hydroxide; copper sulfide; curly malachite; namuwite; sodium copper(II) formate; verdigris

Online: 22 March 2021 (11:50:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0156.v1

A Proof of the Riemann Hypothesis Based on Hadamard Product

Fayez Alhargan

Subject: Computer Science And Mathematics, Mathematics Keywords: the Riemann Hypothesis; the functional equation; the Riemann zeta function; Hadamard Product

Online: 6 August 2020 (10:38:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0513.v1

Ethical Issues and Challenges in Social Media: A Current Scenario

Dr. Bharat Dhiman

Subject: Social Sciences, Media Studies Keywords: Ethics, Social Media; Facebook; Instagram; Snapchat; Personal Information

Online: 29 March 2023 (15:39:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0002.v1

M2M Security Technology of CPS Based on Blockchains

Yin Shiyong, Jin song Bao, Zhang Yiming, Huang Xiaodi

Subject: Engineering, Mechanical Engineering Keywords: blockchain; M2M; CPS; cotton spinning production

Online: 2 August 2017 (12:40:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0044.v1

Effect of Constitutive Equations on Prediction Accuracy for Springback in Cold Stamping of TRIP1180

Ki-Young Seo, Jae-Hong Kim, Hyun-Seok Lee, Ji Hoon Kim, Byung-Min Kim

Subject: Engineering, Mechanical Engineering Keywords: advanced high strength steel; yield function; hardening model; springback; deformation mode

Online: 8 March 2017 (04:51:37 CET)

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Preprint REVIEW | doi:10.20944/preprints201707.0074.v1

The Stem Cell Division Theory of Cancer

Miguel López-Lázaro

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: cancer etiology; carcinogenesis; cancer prevention; stem cells; cancer stem cells; stem cell environment; cells of origin in cancer; somatic mutation theory of cancer

Online: 26 July 2017 (08:42:41 CEST)

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All cancer registries constantly show striking differences in cancer incidence by age and among tissues. For example, lung cancer is diagnosed hundreds of times more often at age 70 than at age 20, and this cancer in nonsmokers occurs thousands of times more frequently than heart cancer in smokers. An analysis of these differences using basic concepts in cell biology indicates that cancer is the end-result of the accumulation of cell divisions in stem cells. In other words, the main determinant of carcinogenesis is the number of cell divisions that the DNA of a stem cell has accumulated in any type of cell from the zygote. Cell division, process by which a cell copies and separates its cellular components to finally split into two cells, is necessary to produce the large number of cells required for living. However, cell division can lead to a variety of cancer-promoting errors, such as mutations occurring during DNA replication, chromosome aberrations arising during mitosis, errors in the distribution of cell-fate determinants between the daughter cells, and failures to restore physical interactions with other tissue components. Some of these errors are spontaneous, others are promoted by endogenous DNA damage occurring during quiescence, and others are influenced by pathological and environmental factors. The cell divisions required for carcinogenesis are primarily caused by multiple local and systemic physiological signals rather than by errors in the DNA of the cells. As carcinogenesis progresses, the accumulation of DNA errors promotes cell division and eventually triggers cell division under permissive extracellular environments. The accumulation of cell divisions in stem cells drives not only the accumulation of the DNA alterations required for carcinogenesis, but also the formation and growth of the abnormal cell populations that characterize the disease. This model of carcinogenesis provides a new framework for understanding the disease and has important implications for cancer prevention and therapy.

Preprint ARTICLE | doi:10.20944/preprints201902.0017.v1

Biodiesel Production (FAEEs) by Heterogeneous Combi-Lipase Biocatalysis Using Wet Extracted Lipids from Microalgae

Alejandra Sánchez-Bayo, Victoria Morales, Rosalía Rodríguez, Gemma Vicente, Luis Fernando Bautista

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: FAEEs; biodiesel; mixed biocatalysts; lipases; microalgae

Online: 2 February 2019 (03:23:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0066.v1

The Effects of Load on Transmural Differences in Contraction of Isolated Mouse Ventricular Cardiomyocytes

Anastasia Khokhlova, Gentaro Iribe, Leonid Katsnelson, Keiji Naruse, Olga Solovyova

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: ventricular transmural heterogeneity; cellular mechanics; load dependency; calcium transient; mechano-calcium feedback

Online: 13 December 2016 (09:49:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0146.v1

Early Childhood Dental Caries, Mouth Pain, and Malnutrition in the Ecuadorian Amazon Region

Marvin So, Yianni A. Ellenikiotis, Hannah M. Husby, Cecilia Leonor Paz, Brittany Seymour, Karen Sokal-Gutierrez

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: early childhood caries; mouth pain; malnutrition; ecuador; community-based intervention

Online: 24 April 2017 (05:43:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201705.0217.v1

Cold Wall CVD (CWCVD) in the Synthesis of Few Layered Graphene on Ni

Mohammad Faisal, Sudipta Bhattacharyya, Pika Jha, Anil Agarwal, P. K. Chaudhury, S. S. Islam, M. Husain

Subject: Chemistry And Materials Science, Nanotechnology Keywords: graphene; chemical vapor deposition; nanomaterials

Online: 30 May 2017 (09:50:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0085.v1

Modeling and Simulation of Passenger Flow Distribution in Urban Rail Transit Hub Platform

Long Gao, Limin Jia

Subject: Engineering, Control And Systems Engineering Keywords: passenger flow distribution integrating model; urban rail transit hub platform; simulation and application; performance evaluation; traffic safety and service level

Online: 26 September 2016 (08:11:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0041.v1

Association between Excessive Use of Mobile Phone and Insomnia and Depression among Japanese Adolescents

Tamura Haruka, Tomoko Nishida, Akiyo Tsuji, Hisataka Sakakibara

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: adolescents; depression; insomnia; mobile phone; Japanese

Online: 7 April 2017 (04:33:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0048.v1

Using GIS and Artificial Neural Network for Deforestation Prediction

Vahid Ahmadi

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: land-cover change; deforestation; neural network; GIS

Online: 7 March 2018 (04:58:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0079.v2

Sodium and Potassium Intake in Healthy Adults in Thessaloniki Greater Metropolitan Area—The SING (Salt Intake in Northern Greece) Study

Eleni Vasara, Georgios Marakis, Joao Breda, Petros Skepastianos, Maria Hassapidou, Anthony Kafatos, Nikolaos Rodopaios, Alexandra A. Koulouri, Francesco P. Cappuccio

Subject: Biology And Life Sciences, Food Science And Technology Keywords: salt; sodium; potassium; intake; MedDietScore; Greece

Online: 21 April 2017 (07:36:43 CEST)

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A reduction in population sodium (as salt) consumption is one of the most cost-effective strategies to reduce the burden of cardiovascular disease and it is a global health priority. High potassium intake is also recommended to reduce cardiovascular disease. To establish effective policies for setting targets and monitoring effectiveness within each country, the current level of consumption should be known. Greece lacks data on actual sodium and potassium intakes. The aim of the present study was therefore to assess dietary salt (using sodium as biomarker) and potassium intakes in a sample of healthy adults in northern Greece and to determine whether adherence to a Mediterranean diet is related to different sodium intakes or sodium-to-potassium ratio. A cross-sectional survey was carried out in Thessaloniki greater metropolitan area (northern Greece) (n=252, aged 18-75 years, 45.2% males). Participants’ dietary sodium and potassium intakes were determined by 24h urinary sodium and potassium excretions. In addition, we estimated their adherence to Mediterranean diet by the use of an 11-item MedDietScore (range 0-55). The mean sodium excretion was 175 (SD 72) mmol/day, equivalent to 4,220 (1,745) mg of sodium or 10.7 (4.4) g of salt per day and potassium excretion was 65 (25) mmol/day, equivalent to 3,303 (1,247) mg/day. Men had higher sodium and potassium excretions compared to women. Only 5.6% of the sample had salt intake <5g/d, which is the target intake recommended by the WHO. Mean sodium-to-potassium excretion ratio was 2.82 (1.07). There was no significant difference in salt or potassium intake or their ratio across MedDietScore quartiles. No significant relationships were found between salt intake and adherence to Mediterranean diet, suggesting that the perception of the health benefits of the Mediterranean diet does not hold when referring to salt consumption. These results suggest the need for a larger nation-wide survey on salt intake in Greece and underline the importance of continuation of salt reduction initiatives in Greece.

Preprint ARTICLE | doi:10.3390/sci1020038

Trend Analysis of Temperature Data for Narayani River Basin, Nepal

Mohan Bahadur Chand, Bikas Chandra Bhattarai, Prashant Baral, Niraj Shankar Pradhananga

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: climate change; temperature trend; Himalaya; river basin; Nepal

Online: 9 July 2019 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202005.0105.v1

Analytical Descriptions of High-Tc Cuprates by Introducing Rotating Holes and a New Model to Handle Many-Body Interactions

Shinichi Ishiguri

Subject: Physical Sciences, Condensed Matter Physics Keywords: high-Tc cuprates; macroscopic boson; many-body interactions; pseudo gap; critical temperature; anomaly metal phase; conservation of angular momentum; attractive force; Cooper pair

Online: 7 May 2020 (05:45:04 CEST)

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