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Deciphering Salt Tolerance Key Genes in Maize Inbred Lines via Time-Series Transcriptomics and Machine Learning
Tongwen Shang
,Xiaomei Zhang
,Lu Tian
,Yuan Li
,Dongqing Zhang
,Youqiang Li
,Kaiyue Liu
,Shuzhe Wang
,Zhaobin Chen
,Yajie Zhao
+3 authors
Posted: 10 July 2026
Morphological and Biochemical Responses of Pinus radiata Embryogenic Cultures to Elicitors, Salinity and Heat Stress
Mareling García-Madrigal
,Dario Vasquez-Quesada
,Daniela Benavides-Villegas
,Ander Castander-Olarieta
,Itziar Aurora Montalbán
,Jason Pérez
,Paloma Moncaleán Guillén
Posted: 10 July 2026
From Physical Grids to Cyber-Energy Digital Twins: Modeling Power System Components for Cyberattack Assessment
Roberto Ciavarella
,Maria Valenti
Posted: 10 July 2026
Aspects of the Pathogenesis of Skin Complications in the Stump-Prosthesis System in Dynamics: The Role of Bacterial and Mycological Dysbiosis
Denis V. Shcherbakov
,Evgeny E. Achkasov
,Ekaterina A. Shashina
,George V. Nesterov
,Alina I. Lezinova
,Tatyana M. Khodykina
,Nina A. Ermakova
,Oleg V. Mitrokhin
Posted: 10 July 2026
Investigating the Effect of UV Light on Marangoni Flow and Drainage of Aqueous Photoswitchable Microscale Foams
Nastaran Rezaee
,John Aunna
,Jamal Naser
Posted: 10 July 2026
MemANS: Event-Driven In-Memory Agentic Name Search for Efficient Multimodal Misinformation Detection on a Balanced Fakeddit Benchmark
Elyson De La Cruz
,Renjith Kathalikkattil Ravindran
,Ruthvik Yedla
,Sumanth Banakar
,Venkatesh Ankarla Sri Ramuloo
,Madhurika Aila
,Varalakshmi Thota
,Karthik Meduri
Posted: 10 July 2026
Protection of Traditional Ecological Knowledge in Dam Development and GLOF Mitigation: A Comprehensive Review
Raj Kumar
,Saurabh Sharma
Posted: 10 July 2026
Development of an Extreme Learning Machine Approach to Upgrade Low/Mid to High Resolution HLA Data Improving the Usability of Donor Data from Registries
Stavros Kepentzis
,Theofanis Chatzistamatiou
,Jason Digalakis
,Ourania Petropoulou
,George K. Matsopoulos
,Dimitris D. Koutsouris
Posted: 10 July 2026
Fast and Interpretable Estimation of Amino AcidResidue Surface Accessibility Based on Protein Contact Graph
Andrey Timofeev
,Alexander Bratchikov
,Alexander Anufriev
Posted: 10 July 2026
Beyond the Rulebook: A Randomized Controlled Trial of Management-Based Anti-Doping Education for Young Elite Athletes in a Developing-Nation Context
Zemikael Getu Yemiru
,Sisay Mengestu
,Tefera Tadesse
Posted: 10 July 2026
Quaternions as Quantization: The 44-Vector Lattice, the Discrete–Continuous Bridge, and the Geometric Origin of Quantum Non-Commutativity
Yuxuan Zhang
,Weitong Hu
,Wei Zhang
Posted: 10 July 2026
Genetic Diversity and Hospital Circulation of Opportunistic Pathogens in COVID19 ICUs: WholeGenome Sequencing Data
Svetlana S. Smirnova
,Dmitry D. Avdyunin
,Yulia S. Stagilskaya
,Anastasia A. Kameneva
,Tatiana A. Platonova
,Nikolai N. Zhuikov
,Tarek M. Itani
,Aleksandr V. Semenov
The COVID-19 pandemic led to a dramatic increase in healthcare‑associated infections (HAIs) and antimicrobial resistance (AMR), particularly in intensive care units (ICUs). This study aimed to provide a comprehensive genetic characterisation of opportunistic pathogens (OPs) circulating in the ICUs of two infectious diseases hospitals repurposed for treating severe COVID‑19 patients. Whole‑genome sequencing (WGS) was performed on 175 isolates recovered from patients and the hospital environment (including personal protective equipment, PPE) between 2021 and 2023. The species composition included Klebsiella pneumoniae (n=53), Acinetobacter baumannii (n=60), Staphylococcus aureus (n=20), Enterococcus faecalis (n=20), Escherichia coli (n=10), Proteus mirabilis (n=5), Pseudomonas aeruginosa (n=4), Enterococcus faecium (n=2), and Klebsiella variicola (n=1). Bioinformatic analysis included multilocus sequence typing (MLST), core genome single‑nucleotide polymorphism (SNP) analysis, phylogenetic reconstruction, and in silico detection of resistance and virulence genes and plasmid replicons. Among K. pneumoniae isolates, the high‑risk clone ST512 (47.2%) carrying blaKPC‑3, pmrB(R256G), gyrA(S83I), oqxAB, qacEdelta1 and fosA dominated and showed intra‑hospital spread (9 patients, 7 PPE, 9 surfaces). A. baumannii was represented by ST2 (40.0%, all blaOXA‑23‑positive), ST78 (28.3%, blaOXA‑72/90) and ST19 (3.3%). For E. coli, clonal complex CC14 (including ST1193) carried blaCTX‑M‑15, marR(S3N) and fluoroquinolone resistance mutations. S. aureus isolates were assigned to CC15, CC8, CC22 (MRSA) and CC97. Resistance genes against up to nine antimicrobial classes were identified. Core genome SNP analysis confirmed direct transmission of K. pneumoniae (1–6 SNP differences) between patients and healthcare worker gloves. PPE was a major reservoir (68.4% of environmental isolates). High frequencies of IncF, rep5a/rep16, rep9 and IncC plasmids were detected in E. coli, S. aureus, E. faecalis and P. mirabilis, respectively. The study demonstrates the power of WGS for high‑resolution epidemiological surveillance, confirms the critical role of contaminated PPE in nosocomial transmission, and highlights the dominance of internationally spreading MDR clones in COVID‑19 ICUs.
The COVID-19 pandemic led to a dramatic increase in healthcare‑associated infections (HAIs) and antimicrobial resistance (AMR), particularly in intensive care units (ICUs). This study aimed to provide a comprehensive genetic characterisation of opportunistic pathogens (OPs) circulating in the ICUs of two infectious diseases hospitals repurposed for treating severe COVID‑19 patients. Whole‑genome sequencing (WGS) was performed on 175 isolates recovered from patients and the hospital environment (including personal protective equipment, PPE) between 2021 and 2023. The species composition included Klebsiella pneumoniae (n=53), Acinetobacter baumannii (n=60), Staphylococcus aureus (n=20), Enterococcus faecalis (n=20), Escherichia coli (n=10), Proteus mirabilis (n=5), Pseudomonas aeruginosa (n=4), Enterococcus faecium (n=2), and Klebsiella variicola (n=1). Bioinformatic analysis included multilocus sequence typing (MLST), core genome single‑nucleotide polymorphism (SNP) analysis, phylogenetic reconstruction, and in silico detection of resistance and virulence genes and plasmid replicons. Among K. pneumoniae isolates, the high‑risk clone ST512 (47.2%) carrying blaKPC‑3, pmrB(R256G), gyrA(S83I), oqxAB, qacEdelta1 and fosA dominated and showed intra‑hospital spread (9 patients, 7 PPE, 9 surfaces). A. baumannii was represented by ST2 (40.0%, all blaOXA‑23‑positive), ST78 (28.3%, blaOXA‑72/90) and ST19 (3.3%). For E. coli, clonal complex CC14 (including ST1193) carried blaCTX‑M‑15, marR(S3N) and fluoroquinolone resistance mutations. S. aureus isolates were assigned to CC15, CC8, CC22 (MRSA) and CC97. Resistance genes against up to nine antimicrobial classes were identified. Core genome SNP analysis confirmed direct transmission of K. pneumoniae (1–6 SNP differences) between patients and healthcare worker gloves. PPE was a major reservoir (68.4% of environmental isolates). High frequencies of IncF, rep5a/rep16, rep9 and IncC plasmids were detected in E. coli, S. aureus, E. faecalis and P. mirabilis, respectively. The study demonstrates the power of WGS for high‑resolution epidemiological surveillance, confirms the critical role of contaminated PPE in nosocomial transmission, and highlights the dominance of internationally spreading MDR clones in COVID‑19 ICUs.
Posted: 10 July 2026
The Weighted Generalized Moore-Penrose Inverse in Banach *-Algebras
Huanyin Chen
Posted: 10 July 2026
Identification of a Major QTL and Development of a CAPS Marker Associated with Stem Blight Resistance in BC₁ Populations Derived from Interspecific Crosses Between Asparagus officinalis L. and Asparagus kiusianus Makino
Yanxing Lu
,Yoko Takeuchi
,Emika Kakizoe
,Eri Kato
,Masaru Matsumoto
,Yoshiyuki Yamagata
,Jun-ichiro Masuda
,Yuki Mizunoe
,Keita Tomiyoshi
,Kaori Sakai
+8 authors
Posted: 10 July 2026
The Legal Entitlement of Older Adults to Cardiovascular Care and Rehabilitation versus Its Clinical Implementation: A Scoping Review of Evidence from 1980 to 2025
Damian Sendrowski
,Martyna Kaja Sendrowska
,Aneta Szofer-Sendrowska
,Dariusz Kozłowski
Posted: 10 July 2026
Correlation Between Adolescent Drug Overdose Mortality Rates and United States Census Regions
Isaiah Popoola
,Darleen Bruno
,Mark Richman
Posted: 10 July 2026
3D Gaussian Splatting Rasterization: A Survey
Beizhen Zhao
,Boyi Fu
,Sicheng Yu
,Zijian Wang
,Kaiyong Zhao
,Pengcheng Wu
,Hao Wang
,Steven Hoi
,Hui Xiong
Posted: 10 July 2026
Towards an Axiomatic Theory of Geodesics
Jorge Pereira Fatelo
,Nelson Martins-Ferreira
Posted: 10 July 2026
Learning from Demonstration for Robotic Deburring and Polishing: A Systematic Mapping Study
Ercan Düzgün
Posted: 10 July 2026
Structural Interoperability Between π-Graded Hom-Type Algebras and Rota-Baxter Operators
Xiuzhen Li
,Ruoxi He
,Yalan Zhang
,Guodong Shi
Posted: 10 July 2026
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