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Preprint REVIEW | doi:10.20944/preprints201807.0481.v2

A Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer’s Disease

Rubayat Islam Khan, Saif Shahriar Rahman Nirzhor, Barnaly Rashid

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: protein tau; Alzheimer’s disease; neurodegenerative disease; synaptic dysfunction; Aβ-peptides; tau-imaging

Online: 27 August 2018 (11:25:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0101.v1

TBI and Tau Loss-of-Function Both Affect Naïve Ethanol Sensitivity in Drosophila

Valbona Hoxha, Gaurav Shrestha, Nayab Baloch, Sara Collevechio, Raegan R. Laszczyk, Gregg Roman

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: TBI; Alcohol; Drosophila; Tau

Online: 2 February 2024 (10:36:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0275.v1

Filamentous Aggregates of Tau Proteins Fulfil Standard Amyloid Criteria

Dawid Dułak, Małgorzata Gadzała, Mateusz Banach, Magdalena Ptak, Zdzisław Wisniowski, Leszek Konieczny, Irena Roterman

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: tau protein amyloids; Alzheimer’s disease; tauopathy

Online: 16 July 2018 (10:49:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1403.v1

Liposome Nanoparticle Conjugation and Cell Penetrating Peptide Sequences (CPPs) Enhance the Cellular Delivery of the Tau Aggregation Inhibitor RI-AG03

Niklas Reich, David Allsop, Edward Parkin, Neil Dawson

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Alzheimer’s Disease; Tauopathy; Cell penetrating peptide; Polyarginine; TAT; Liposomes; Nanoparticles; Tau pathology; Tau aggregation inhibitor; Endocytosis

Online: 19 May 2023 (08:06:10 CEST)

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Preprint REVIEW | doi:10.20944/preprints202006.0147.v1

Novel Therapeutic Targets and Biomarkers for the Treatment of Progressive Supranuclear Palsy

Imogen Tyer, Alison Hill

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: PSP; Progressive Supranuclear Palsy; 4R-tau; four-repeat tau; MAPT; Microtubule-associated ligand; PET; Positron Emission Tomography

Online: 12 June 2020 (09:41:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202010.0349.v1

Tau: At the Interface Between Neurodegeneration and Cancer?

Stéphanie Papin, Paolo Paganetti

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: neurodegeneration; tauopathies; cancer, Tau protein, DNA protection

Online: 16 October 2020 (12:31:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0235.v1

Lipid Dys-Homeostasis Contributes to APOE4 Associated AD Pathology

Adina-Nicoleta Lazar, Linda Hanbouch, Lydie Boussicaut, Baptiste Fourmaux, Patricia Daira, Mark John Millan, Nathalie Bernoud-Hubac, Marie-Claude Potier

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: lipid homeostasis; APOE4; Alzheimer’s Disease; Aβ peptide; tau

Online: 16 September 2022 (02:57:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0411.v1

A Combined Cell-Worm Approach to Search for Compounds Counteracting the Toxicity of Tau Oligomers in Vivo

Carmina Natale, Maria Monica Barzago, Luca Colnaghi, Ada De Luigi, Franca Orsini, Luana Fioriti, Luisa Diomede

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: tauopathy; tau protein; oligomers; proteotoxicity; C. elegans; tetracyclines.

Online: 27 July 2022 (05:10:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0645.v1

Heat Stress Modulates the GSK-3β Levels and Tau Phosphorylation

Tushar Dubey, Subashchandrabose Chinnathambi

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Alzheimer’s disease; Tau phosphorylation; Heat stress; GSK-3β

Online: 26 July 2020 (17:04:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0118.v1

The Impact of Nuclear Spin and Isospin of Dirac Particles on the Mass Spectrum of Leptons

Engel Roza

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: Dirac particle; isospin; muon; tau particle; electron mass

Online: 10 May 2019 (10:35:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1279.v1

Medical Radiology in Italy: Current Progress

Alessia Pepe, Filippo Crimì, Federica Vernuccio, Giulio Cabrelle, Amalia Lupi, Chiara Zanon, Sebastiano Gambato, Anna Perazzolo, Emilio Quaia

Subject: Medicine And Pharmacology, Other Keywords: Cardiovascular Imaging; Rectal Imaging; Liver Imaging; Computed Tomography; Magnetic Resonance Imaging; Ultrasound

Online: 19 June 2023 (04:05:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202105.0717.v1

DNA Methylation in Genetic and Sporadic Forms of Neurodegeneration: Lessons From Alzheimers, Related Tauopathies and Genetic Tauopathies

Geraldine Zimmer-Bensch, Hans Zempel

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Alzheimer; TAU; MAPT; epigenetics; neurodegeneration; neurogenetic disease; DNA methylation

Online: 31 May 2021 (09:08:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0448.v2

Diet Control to Achieve Euglycemia Induces Tau Hyperphosphorylation Via AMPK Activation in the Hippocampus of Diabetic Rats

Sang-Don Han, Jun-Ho Lee, Yun-Hee Noh, Mingli Jin, Jin-Seong Kim

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Alzheimer’s disease; Diabetes; Diet control diet; AMPK; Tau hyperphosphorylation

Online: 8 October 2018 (15:32:11 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.2012.v1

Designing Advanced Multistatic Imaging Systems with Optimal 2D Sparse Arrays

Lorena Perez-Eijo, Marcos Arias, Borja González-Valdés, Yolanda Rodriguez-Vaqueiro, Oscar Rubiños-López, Antonio Pino, Ignacio Sardinero-Meirás, Jesús Grajal

Subject: Engineering, Electrical And Electronic Engineering Keywords: Submillimeter wavelength imaging; multistatic imaging; backpropagation imaging; genetic algorithm (GA).

Online: 28 September 2023 (11:46:55 CEST)

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Working Paper REVIEW

Emerging Imaging Methods to Study Whole-Brain Function in Rodent Models

Marija Markicevic, Iurii Savvateev, Christina Grimm, Valerio Zerbi

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Ultrasound imaging; photoacoustic; functional MRI; calcium imaging; rodents; fluorescence imaging

Online: 24 May 2021 (16:12:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints201809.0039.v1

3D Imaging based on Depth Measurement Technologies

Ni Chen, Chao Zuo, Edmund Y. Lam, Byoungho Lee

Subject: Engineering, Electrical And Electronic Engineering Keywords: Three-dimensional imaging; computational imaging; light field; holography; phase imaging

Online: 3 September 2018 (14:07:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0084.v1

Nanoparticles as Contrast Agents for Preclinical and Clinical Bioimaging

Deependra Ban

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Nanomaterial; optical imaging; MRI imaging; nanoparticles

Online: 3 August 2022 (10:43:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202011.0647.v2

Feasibility of Diffusion Weighting with a Local Inside-Out Nonlinear Gradient Coil for Prostate MRI

Enamul Bhuiyan, Andrew Dewdney, Jeffrey Weinreb, Gigi Galiana

Subject: Engineering, Automotive Engineering Keywords: nonlinear gradients; diffusion imaging; prostate imaging

Online: 12 February 2021 (08:51:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202104.0566.v1

Residual Tau-Fluvalinate in Honey Bee Colonies is Coupled with Evidence for Selection for Varroa Destructor Resistance to Pyrethroids

María Benito-Murcia, Carolina Bartolomé, Xulio Maside, José Bernal, José Luis Bernal, María Jesús Nozal, Aránzazu Meana, Cristina Botías, Raquel Martín Hernández, Mariano Higes

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Varroa destructor; mite; resistant populations; acaricide residues; tau-fluvalinate; varroosis

Online: 21 April 2021 (09:42:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0132.v1

Complete Removal of Arbitrarily Strong and Arbitrarily Located Auto Correlation Artifacts in Spectral Domain Optical Coherence Tomography: Demonstration of an Efficient and Cost Effective Technique

Hari Nandakumar, SatyaPrasanna Mallick, Shailesh Srivastava

Subject: Physical Sciences, Optics And Photonics Keywords: optical coherence tomography; imaging systems; tomographic imaging

Online: 12 January 2020 (17:13:24 CET)

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Preprint REVIEW | doi:10.20944/preprints201801.0167.v1

Molecular imaging modalities using nanoprobes for cancer diagnosis

Daryoush Shahbazi-Gahrouei, Pegah Moradi Khaniabadi, Bita Moradi khaniabadi, Saghar Shahbazi-Gahrouei, Mona Fazel

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: molecular imaging; nanoparticles; cancer diagnosis; imaging modalities

Online: 18 January 2018 (05:12:13 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202006.0053.v1

Row Action Algebraic Reconstruction Techniques Implementation in Graphic Cards using SCILAB (Benchmark in Medical Imaging, Seismic Imaging and Walnut Imaging)

Agah Drajat Garnadi, Muhammad Ilyas, M.T. Julianto, S. Nurdiati

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Algebraic iterative reconstruction; ART methods; Row-action methods; Graphics Cards; Tomographic imaging; Medical imaging; Seismic Imaging; Walnut Imaging.

Online: 5 June 2020 (14:27:06 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0513.v1

The MAPT Isoform 0N3R Is Essential for Human Brain Development and Intolerant to Haploinsufficiency – Loss of Function as Disease Mechanism for TAU Associated Disease

Hans Zempel

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: TAU; MAPT; neurodevelopment; neurogenetic and neurodegenerative disease; isoform; disease mechanism; dementia

Online: 7 December 2023 (14:56:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201904.0091.v5

Preference Neural Network

Ayman Elgharabawy, Mukesh Prasad, Chin-Teng Lin, Ayman Elgharabawy

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Preference learning; Multi-label ranking; Neural network; Kendall’s tau; Preference mining

Online: 19 April 2023 (07:43:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202006.0203.v2

SH-SY5Y-derived neurons: A Human Neuronal Model System for Investigating TAU Sorting and Neuronal Subtype-Specific TAU Vulnerability

Michael Bell, Hans Zempel

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: SH-SY5Y-derived neurons; TAU sorting; neuronal identity; tauopathy; Alzheimer’s disease

Online: 23 December 2020 (10:30:47 CET)

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The microtubule-associated protein TAU is sorted into the axon in healthy brain neurons. Somatodendritic missorting of TAU is a pathological hallmark of many neurodegenerative diseases called tauopathies, including Alzheimer’s Disease (AD). Cause, consequence, and (patho)physiological mechanisms of TAU sorting and missorting are understudied, in part also due to the lack of readily available human neuronal model systems. The human neuroblastoma cell line SH-SY5Y is widely used for studying TAU physiology and TAU-related pathology in AD and related tauopathies. SH-SY5Y cells can be differentiated into neuron-like cells (SH-SY5Y-derived neurons) using various substances. This review evaluates whether SH-SY5Y-derived neurons are a suitable model for i) investigating intracellular TAU sorting in general, and ii) with respect to neuron subtype-specific TAU vulnerability. I) SH-SY5Y-derived neurons show pronounced axodendritic polarity, high levels of axonally localized TAU protein, expression of all six major human brain isoforms, and TAU phosphorylation similar to the human brain. As proliferative cells, SH-SY5Y cells are readily accessible for genetic engineering, stable transgene integration and leading-edge genome editing are valuable and promising tools for TAU-related studies. II) Depending on the used differentiation procedure, SH-SY5Y-derived neurons resemble cells of distinct subcortical nuclei, i.e. the Locus coeruleus (LC), Nucleus basalis (NB) and Substantia nigra (SN), all of which early affected in many tauopathies. This allows to analyse neuron-specific TAU isoform expression and intracellular localization, also in the context of vulnerability to TAU pathology. Limitations are e.g. the lack of mimicking age-related tauopathy risk factors and the difficulty to define the exact neuronal subtype of SH-SY5Y-derived neurons. In brief, this review discusses the suitability of SH-SY5Y-derived neurons for investigating TAU (mis)sorting mechanisms and neuron-specific TAU vulnerability in disease paradigms.

Preprint REVIEW | doi:10.20944/preprints202005.0021.v1

Anti Iglon5 Syndrome: What We Know So Far? A Non-Systematic Review

Caroline Figueiredo da Silva, Gustavo Figueiredo da Silva, Washigton Luiz Gomes de Medeiros Junior, Marcus Vinícius Magno Gonçalves

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: anti-IgLON5 disease; sleep disorders; tau protein accumulation; immunotherapy; neurodegenerative diseases

Online: 2 May 2020 (16:26:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1975.v1

ARDS Mortality Prediction Model Using Evolving Clinical Data and Chest Radiograph Analysis

Ana Cysneiros, Tiago Galvão, Nuno Domingues, Pedro Jorge, Luis Bento, Ignacio Martin-Loeches

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: ARDS; imaging

Online: 29 January 2024 (04:44:44 CET)

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Preprint REVIEW | doi:10.20944/preprints202404.1202.v1

A Review on Clinical Optoacoustic Imaging: Are We Close to Clinical Adoption?

Sergio Contador, Jorge Ripoll, Eduardo Lage, Juan Aguirre

Subject: Engineering, Bioengineering Keywords: clinical optoacoustic imaging; clinical photoacoustic imaging; clinical translation

Online: 18 April 2024 (08:09:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0563.v1

Experimental Validation of a Microwave Imaging Method for Shallow Buried Target Detection by Under-Sampled Data and a Non-Coperative Source

Adriana Brancaccio, Giovanni Leone, Rocco Pierri, Raffaele Solimene

Subject: Engineering, Automotive Engineering Keywords: Radar imaging; target detection; experimental measurements; Microwave imaging.

Online: 23 June 2021 (10:25:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202211.0281.v1

Implementation of Large Area Diffractive Lens Using Multiple Sub-Aperture Diffractive Lenses and Computational Reconstruction

Shivasubramanian Gopinath, Periyasamy Angamuthu Praveen, Tauno Kahro, Andrei Bleahu, Francis Gracy Arockiaraj, Daniel Smith, Soon Hock Ng, Saulius Juodkazis, Kaupo Kukli, Aile Tamm, Vijayakumar Anand

Subject: Physical Sciences, Optics And Photonics Keywords: diffractive lens; imaging; Lucy-Richardson-Rosen algorithm; holography; incoherent imaging; telescope; photolithography; computational imaging

Online: 15 November 2022 (07:52:16 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.0227.v1

The Impact of Apolipoprotein E (APOE) Epigenetics on Aging and Sporadic Alzheimer’s Disease

Madia Lozupone, Vittorio Dibello, Rodolfo Sardone, Fabio Castellana, Roberta Zupo, Luisa Lampignano, Ilaria Bortone, Antonio Daniele, Antonello Bellomo, Vincenzo Solfrizzi, Francesco Panza

Subject: Biology And Life Sciences, Aging Keywords: apolipoprotein E; Alzheimer’s disease; methylation; dementia; epigenetics; tau protein; amyloid-β; longevity

Online: 3 November 2023 (10:00:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.0622.v1

Tau-Marin Mucoadhesive Gel for Prevention and Treatment of Periodontal Diseases

Giuseppe Giannini, Irene Ragusa, Giulia Nerina Nardone, Sara Soldi, Marina Elli, Piera Valenti, Luigi Rosa

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Tau-Marin; Mucoadhesive gel; oral formulation; probiotics; periodontitis; periodontal diseases; slow delivery

Online: 10 July 2023 (11:34:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints201809.0075.v1

Untangling the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases

Daniela Sarnataro

Subject: Biology And Life Sciences, Virology Keywords: A; aggregation; amyloid; APP; misfolding; prion protein; prion-like; PrP; seeds; tau

Online: 4 September 2018 (16:51:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1199.v1

Live Cell Imaging by Single-Shot Common-Path Wide Field-of-View Reflective Digital Holographic Microscope

Manoj Kumar, Takashi Murata, Osamu Matoba

Subject: Physical Sciences, Optics And Photonics Keywords: quantitative phase imaging; digital holographic microscopy; live cell imaging.

Online: 16 January 2024 (14:00:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202112.0124.v1

Nanotechnology as a Versatile Tool for ¹⁹F-MRI Agent’s Formulation: A Glimpse into the Use of Perfluorinated and Fluorinated Compounds in Nanoparticles

Joice Maria Joseph, Maria Rosa Gigliobianco, Bita Mahdavi Firouzabadi, Roberta Censi, Piera Di Martino

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: Magnetic resonance imaging; perfluorocarbons; imaging agent; nanosystems; nanoparticles; fluorine

Online: 8 December 2021 (12:18:26 CET)

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Preprint REVIEW | doi:10.20944/preprints201808.0210.v1

Applications of Oxygen-Carrying Micro/Nanobubbles: a Potential Approach to Enhance Photodynamic Therapy and Photoacoustic Imaging

M. Saad Khan, Jangsun Hwang, Kyungwoo Lee, Yonghyun Choi, Kyobum Kim, Hyung-Jun Koo, Jong Wook Hong, Jonghoon Choi

Subject: Chemistry And Materials Science, Nanotechnology Keywords: microbubbles; nanobubbles; photoacoustic imaging; ultrasonic imaging; ROS; oxygen delivery

Online: 11 August 2018 (18:49:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints201705.0064.v1

Multispectral, Fluorescent and Photoplethysmographic Imaging for Remote Skin Assessment

Janis Spigulis

Subject: Physical Sciences, Optics And Photonics Keywords: multispectral skin imaging; skin autofluorescence and photobleaching; photoplethysmography imaging

Online: 8 May 2017 (12:19:30 CEST)

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Preprint REVIEW | doi:10.20944/preprints201808.0295.v1

Review of Biomedical Applications of Contactless Imaging of Neonates using Infrared Thermography and Beyond

Abbas K. AlZubaidi, Yahya Ethawi, Georg M. Schmoelzer, Sherif Sherif, Michael Narvey, Molly Seshia

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: NICU; Physio-features; Neonatal imaging; Infrared thermography; Optical coherence tomography; Tissue optics; Near-infrared imaging; Short-wave infrared imaging; Visible light imaging

Online: 17 August 2018 (02:27:17 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202210.0257.v1

Single Shot Lensless Interferenceless Phase Imaging of Biochemical Samples Using Synchrotron Near Infrared Beam

Molong Han, Daniel Smith, Soon Hock Ng, Tomas Katkus, Aravind Simon John Francis Rajeswary, Praveen P A, Keith R Bambery, Mark J Tobin, Jitraporn Vongsvivut, Saulius Juodkazis, Vijayakumar Anand

Subject: Physical Sciences, Optics And Photonics Keywords: Phase imaging, bioimaging; synchrotron; near infrared beam; holography; incoherent optics; chemical imaging; phase retrieval; 3D imaging.

Online: 18 October 2022 (08:28:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1220.v1

Integrating a Fundus Camera with High Frequency Ultrasound for Precise Ocular Lesion Assessment

Alfa Rossi, Yushun Zeng, Mojtaba Rahimi, Taeyoon Son, Michael J. Heiferman, Chen Gong, Xin Sun, Mohammad Soleimani, Ali R. Djalilian, Mark S. Humayun, Qifa Zhou, Xincheng Yao

Subject: Engineering, Bioengineering Keywords: transparent ultrasound-transducer; widefield fundus camera; retinal imaging; ultrasound imaging

Online: 16 January 2024 (10:28:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0774.v1

Myocardial Perfusion Imaging and C-reactive Protein in Myo-Cardial Ischemia: A Retrospective Single-Center Study

Aidonis Rammos, Aris Bechlioulis, Areti Kekiopoulou, Pavlos Kekiopoulos, Christos S. Katsouras, Chrissa Sioka

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: C-reactive protein; ischemia; SPECT; myocardial perfusion imaging; cardiac imaging

Online: 10 January 2024 (10:08:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0712.v1

Synthetic Ultra-wideband Transceiver for Millimeter-wave Imaging Applications

Amir Mirbeik, Laleh Najafizadeh, Negar Ebadi

Subject: Engineering, Electrical And Electronic Engineering Keywords: Millimeter-wave Imaging; Transceiver; Circuit; Biomedical imaging; ultra-wideband; CMOS

Online: 12 September 2023 (03:21:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1238.v1

Using Schlieren Imaging and Radar Acoustic Sounding System for the Detection and Characterization of Close-in Air Turbulence

Samantha Gordon, Graham Brooker

Subject: Engineering, Other Keywords: ultrasound modulated schlieren imaging; radio acoustic sounding; RASS; imaging; ultrasound

Online: 17 August 2023 (13:10:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0010.v1

Deep Deconvolution of Object Information Modulated by a Refractive Lens Using Lucy-Richardson-Rosen Algorithm

Praveen PA, Francis Gracy Arockiaraj, Shivasubramanian Gopinath, Daniel Smith, Tauno Kahro, Sandhra-Mirella Valdma, Andrei Bleahu, Andra Naresh Kumar Reddy, Tomas Katkus, Aravind Simon John Francis Rajeswary, Rashid. A Ganeev, Siim Pikker, Kaupo Kukli, Aile Tamm, Saulius Juodkazis, Vijayakumar Anand

Subject: Physical Sciences, Optics And Photonics Keywords: imaging; incoherent optics; Lucy-Richardson-Rosen algorithm; deblurring; refractive lens; com-putational imaging; holography; 3D imaging; deconvolution

Online: 1 August 2022 (07:45:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1046.v1

Differential Regulation of Age-Dependent Neurodegeneration and Buildup Human Phosphorylated Tau in Neurons in Drosophila by ATG14L, ATG6/Beclin 1 and VPS34

Chia-Lung Chuang, Yan-Rui Lin, Yi-Han Tu, Hao Chi, Tzu-Kang Sang, Hui-Yun Chang

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Autophagy; Alzheimer’s disease; ATG14L; Beclin 1; VPS34; Neurodegenerative disease; GFP-mCherry-LC3; Tau

Online: 20 February 2024 (06:35:17 CET)

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Preprint REVIEW | doi:10.20944/preprints202309.0365.v1

Mammalian Models in Alzheimer's Research: An update

Himadri Sharma, Keun-A Chang, John Hulme, Seong Soo A An

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Animal model; Alzheimer’s Disease; Amyloid β; Tau Protein; LOAD models; Transgenic Murine Models

Online: 6 September 2023 (04:02:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1784.v1

CSF Soluble TREM2 Concentrations Correlate With the Severity of Neurofibrillary Degeneration, Cognitive Impairment, and Inflammasome Activation in Alzheimer’s Disease

Ena Španić Popovački, Mirjana Babić Leko, Lea Langer Horvat, Klara Brgić, Željka Vogrinc, Marina Boban, Nataša Klepac, Fran Borovečki, Šimić Goran

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer’s disease; cerebrospinal fluid; inflammasome; microglia; mild cognitive impairment; plasma; tau protein; TREM2

Online: 25 May 2023 (09:40:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints201706.0068.v1

Human MAP tau based targeted cytolytic fusion proteins

Olusiji Akinrinmade, Sandra Jordaan, Dmitrij Hristodorov, Radoslav Mladenov, Neelakshi Mungra, Shivan Chetty, Stefan Barth

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: human cytolytic fusion proteins; immunotherapy; microtubule associated protein tau (MAP); cancer; inflammatory diseases

Online: 15 June 2017 (12:02:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints202311.0105.v1

Leukodystrophy Imaging: Insights for Diagnostic Dilemmas

Rajvi N Thakkar, Drashti Patel, Ivelina P. Kioutchoukova, Raja Al-Bahou, Pranith Reddy, Devon T. Foster, Brandon Lucke-Wold

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Leukodystrophies; Demyelinating disorders; Magnetic Resonance Imaging; Myelin Imaging; White matter disorders

Online: 2 November 2023 (08:20:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202206.0102.v1

MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models

Marta Guardiola, Walid Dghoughi, Roberto Sont, Alejandra Garrido, Sergi Marcoval, Luz María Neira, Ignasi Belda, Glòria Fernández-Esparrach

Subject: Medicine And Pharmacology, Other Keywords: endoscopes; medical diagnostic imaging; microwave antenna arrays; microwave imaging; colorectal cancer

Online: 7 June 2022 (09:55:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0049.v1

A Semi-Synthetic Study of Multidimensional Imaging using a Scattering Lens

Shivasubramanian Gopinath

Subject: Physical Sciences, Optics And Photonics Keywords: Computational Imaging; Non-linear reconstruction (NLR); Holography; scattering lens; 3D imaging

Online: 3 June 2022 (12:50:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.1837.v1

The Role of Tau Pathology in Alzheimer’s Disease and Down Syndrome

Ann-Charlotte E Granholm, Eric D. Hamlett

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Down syndrome (DS); Alzheimer’s disease (AD); neurofibrillary tangles (NFTs); seeding competent p-Tau; neuropathology.

Online: 25 January 2024 (12:11:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1071.v1

Microglial-targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice

Meixiang Huang, Carolyn Tallon, Xiaolei Zhu, Kaitlyn DJ Huizar, Silvia Picciolini, Ajit G. Thomas, Lukas Tenora, Wathsala Liyanage, Francesca Rodà, Alice Gualerzi, Rangaramanujam M. Kannan, Marzia Bedoni, Rana Rais, Barbara S. Slusher

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Alzheimer’s disease; DPTIP; hydroxyl PAMAM dendrimer; D-DPTIP; extracellular vesicles; neutral sphingomyelinase 2; tau

Online: 15 August 2023 (09:01:43 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202109.0133.v1

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium

Gregory D. Scott, Moriah R. Arnold, Thomas G. Beach, Christopher H. Gibbons, Anumantha G. Kanthasamy, Russell M. Lebovitz, Afina W. Lemstra, Leslie M. Shaw, Charlotte E. Teunissen, Henrik Zetterberg, Angela S. Taylor, Todd C. Graham, Bradley F. Boeve, Stephen N. Gomperts, Neill R. Graff-Radford, Charbel E.-H. Moussa, Kathleen L. Poston, Liana S. Rosenthal, Marwan N. Sabbagh, Ryan R. Walsh, Miriam T. Weber, Melissa J. Armstrong, Jee A. Bang, Andrea C. Bozoki, Kimiko Domoto-Reilly, John E. Duda, Jori E. Fleisher, Douglas R. Galasko, James E. Galvin, Jennifer G. Goldman, Samantha K. Holden, Lawrence S. Honig, Daniel E. Huddleston, James B. Leverenz, Irene Litvan, Carol A. Manning, Karen S. Marder, Alexander Y. Pantelyat, Victoria S. Pelak, Douglas W. Scharre, Sharon J. Sha, Holly A. Shill, Mari Zoltan, Joseph F. Quinn, David J. Irwin

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: cerebrospinal fluid; alpha-synuclein; skin biopsy; seeded aggregation assays; tau, amyloid; Lewy body dementia

Online: 7 September 2021 (16:26:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202107.0307.v1

Quantitative Approaches to Study Retinal Neurogenesis

Diego Perez-Dones, Mario Ledesma-Terron, David G Míguez

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Retinogenesis; Quantiative Biology; Imaging

Online: 13 July 2021 (12:18:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints201709.0160.v1

Advances in Fluorescent Single-Chain Nanoparticles

Julen De-La-Cuesta, Edurne Gonzalez, José A. Pomposo

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Nanoparticles; fluorescence; optical imaging

Online: 29 September 2017 (18:36:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201804.0076.v1

Leverage and Volatility Feedback Effects and Conditional Dependence Index: A Nonparametric Study

Yiguo Sun, Ximing Wu

Subject: Business, Economics And Management, Finance Keywords: conditional dependence index; Kendall's Tau; leverage effect; nonparametric copula; tail dependence index; volatility feedback effect

Online: 6 April 2018 (11:17:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1355.v1

Influence of MRI Follow-Up on Treatment Decisions during Standard Concomitant and Adjuvant Chemotherapy in Patients with Glioblastoma: Less Is More?

Bart R.J. Van Dijken, Annerieke R. Doff, Roelien H. Enting, Peter Jan Van Laar, Hanne-Rinck Jeltema, Rudi A. Dierckx, Anouk Van der Hoorn

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Glioblastoma; Magnetic Resonance Imaging; Treatment response assessment; Treatment follow-up; Pseudoprogression; Perfusion Imaging

Online: 20 September 2023 (10:47:56 CEST)

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Working Paper ARTICLE

Compressed Orthogonal Coded Multiplexing Wide-band Millimeter Wave Imaging - A Numerical Study

Hao Tu, Xiangxin Meng, Taorong Liu, Hui Feng, Shuai Wu

Subject: Engineering, Electrical And Electronic Engineering Keywords: millimeter wave imaging; orthogonal coded multiplexing; compressed sensing; real-time imaging; dynamic range

Online: 10 November 2019 (09:40:50 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints201804.0335.v1

Mapping the Distribution of Particles in Hydrogel in Use for Nanoplasmonic Biosensors: A Comparison of Preparation Methods

Harald Ian Muri, Linh Hoang, Dag Roar Hjelme

Subject: Chemistry And Materials Science, Nanotechnology Keywords: metal nanocomposite hydrogels; particle distribution; nanoplasmonic sensor; preparation methods; SEM imaging; volume imaging

Online: 26 April 2018 (08:16:47 CEST)

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The distribution of noble metal nanoparticles in hydrogels are influencing their nanoplasmonic response and signal used for biosensor purposes. By controlling the particle distribution, it is possible to obtain new nanoplasmonic features with new sensing modalities. Particle distributions can be characterized by using volume-imaging methods such as the focused ion beam-scanning electron microscope (FIB-SEM) and the serial block-face scanning electron microscopy (SBFSEM) techniques . Since the pore structure of hydrogels is contained by the water absorbed in the polymer network it may pose challenges for volume-imaging based on electron microscope techniques since the sample must be in a vacuum chamber. The structure of hydrogels can be conserved by choosing appropriate preparation methods, which also depends on the composition of the hydrogel used. In this paper, we have prepared low-weight percentage hydrogels, with and without gold nanorods (GNR) for conventional SEM imaging by using two different drying techniques; (1) the critical point drying (CPD) technique and (2) hexamethyldisilazane (HMDS) drying of hydrogels. A qualitative characterization of the GNR-hydrogels was carried out to study the GNRs positioned in the polymer network. The effect of the two different drying methods on the hydrogel morphology were also compared. The use of HMDS as an alternative to the CPD has several advantages involving less parametrical variables for drying, involving less effort, being cost-effective, and requires no equipment use. In addition, choosing an optimized sample preparation method for SEM with optimized imaging parameters is highly important for obtaining accurate information about materials that is not correlated to artifacts. Hence, the results obtained from the preparation methods and SEM imaging parameters in this paper are useful for developing methods for mapping the metal particle distributions in micro-hydrogels by using FIB-SEM and SBFSEM techniques.

Preprint REVIEW | doi:10.20944/preprints202403.1342.v2

Utility of ChatGPT-4 in Musculoskeletal Imaging: A Narrative Review

Salha Albahkali, Saud Alawad

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: musculoskeletal imaging; Artificial Inetellgence; ChatGPT

Online: 28 March 2024 (14:48:25 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.2208.v1

DNA Nanotechnology-Empowered Fluorescence Imaging of APE1 Activity

Hui He, Xiaojun Liu, Yuchen Wu, Lanlin Qi, Jin Huang, Yan Zhou, Jiahao Zeng, Kemin Wang, Xiaoxiao He

Subject: Chemistry And Materials Science, Nanotechnology Keywords: APE1; DNA nanotechnology; fluorescence imaging

Online: 30 June 2023 (10:09:07 CEST)

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Preprint REVIEW | doi:10.20944/preprints202301.0456.v2

Quantitative Image Processing for Three-Dimensional Episcopic Images of Biological Structures: Current State and Future Directions

Natalie Aroha Holroyd, Claire Walsh, Lucie Gourmet, Simon Walker-Samuel

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: episcopic; imaging; microscopy; annotation; quantification

Online: 6 March 2023 (13:52:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0367.v1

Re-Visiting Viking Vinland: II. 'Virtual Excavation' of 'Keelness', a Viking Shipwreck Site in North America

Royce Haynes, Matthew Franklin, Jamie Goosney, Denise Goosney

Subject: Arts And Humanities, Archaeology Keywords: Viking; Vinland; Keelness; remote imaging

Online: 20 January 2023 (01:48:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0137.v1

Re-Visiting Viking Vinland: I. Locating 'Keelness', a Viking Shipwreck Site in North America

Royce Haynes

Subject: Arts And Humanities, Archaeology Keywords: Viking; Vinland; Keelness; remote imaging

Online: 8 December 2022 (01:25:31 CET)

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Preprint REVIEW | doi:10.20944/preprints202208.0312.v1

Intranasal Dexmedetomidine as Sedative for Medical Imaging in Young Children: A Systematic Review to Provide a Roadmap for an Evidence-guided Clinical Protocol

Kato Hermans, Larissa Ramaekers, Jaan Toelen, Koen Vanhonsebrouck, Karel Allegaert

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: procedural sedation; children; dexmedetomidine; imaging

Online: 17 August 2022 (09:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0456.v1

SiO2 Coated Up-conversion Nanomaterial Doped with Ag Nanoparticles for Micro-CT Imaging

Wei Zhang, Yanli Lu, YANG ZANG, Jinhui Han, Qingyun Xiong, Jinping Xiong

Subject: Chemistry And Materials Science, Biomaterials Keywords: up-conversion; nanomaterials; CT imaging

Online: 24 November 2021 (13:04:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0529.v1

Photoacoustic Imaging for Periodontal Disease Examination

Mitrayana Mitrayana, Atika Windra Sari, Rini Widyaningrum

Subject: Physical Sciences, Acoustics Keywords: diode laser, imaging, periodontal, photoacoustic.

Online: 23 July 2021 (08:10:44 CEST)

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Preprint REVIEW | doi:10.20944/preprints202107.0031.v1

Recent Progress of SERS Nanoprobe for pH Detecting and its Application in Biological Imaging

Lei Zhang, Qianqian Zhao, Zhitao Jiang, Jingjing Shen, Weibing Wu, Xingfen Liu, Quli Fan, Wei Huang

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: pH; SERS; probe; detection; imaging

Online: 1 July 2021 (14:17:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0264.v2

Microfluidic Live-Imaging Technology to Perform Research Activities in 3D Models

Arnaud Martino Capuzzo, Daniele Vigo

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Microfluidic; CELLviewer; Spheroids; Imaging; Biomedical;

Online: 12 March 2021 (11:29:04 CET)

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Morphological dissimilarity and its evolution over time are one of the most unexpected variations found when comparing cell cultures in 2D and 3D. Monolayer cells appear to flatten in the lower part of the plate, adhering to and spreading in the horizontal plane while not extending vertically. Consequently, cells developed in two dimensions have a forced apex-basal polarity. Co-cultivation and crosstalking between multiple cell types, which control development and formation in the in vivo counterpart, are possible in 3D cultures. With or without a scaffold matrix, 3D model culture may exhibit more in vivo-like morphology and physiology. 3D cultures mimic relevant physiological cellular processes, transforming them into one-of-a-kind drug screening platforms. The structures and dynamics of regulatory networks, which are increasingly studied with live-imaging microscopy, must be considered to help and guarantee the functional maintenance of a 3D structure. However, commercially available technologies that can be used for current laboratory needs are minimal, despite the need to make it easier to acquire cellular kinetics with high spatial and temporal resolution, in order to improve visual efficiency and, as a result, experimentation performance. The CELLviewer is a newly developed multi-technology instrument that integrates and synchronizes the work of various scientific disciplines. The aim of this study is to test the device using two different models: a single Jurkat cell and an MCF-7 spheroid. The two models are loaded into the microfluidic cartridge for each experiment after they have been grown and captured in time-lapse for a total of 4 hours. The samples used are tracked under the operation of the optics after adaptive autofocus, while slipping inside the cartridge chamber, and the 3D rotation was successfully obtained experimentally. The MitoGreen dye, a fluorescence marker selectively permeable to live cells, was then used to determine cell viability. To measure the model diameter, construct fluorescence intensity graphs along a straight line passing through the cell, and visualize the spatial fluorescence intensity distribution in 3D, ImageJ software was used.

Preprint REVIEW | doi:10.20944/preprints202009.0720.v1

A Perspective on Cell Tracking with Magnetic Particle Imaging

Olivia C. Sehl, Julia J. Gevaert, Kierstin P. Melo, Natasha N. Knier, Paula J. Foster

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: magnetic particle imaging, cell tracking

Online: 29 September 2020 (16:35:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201912.0173.v1

An Efficient and Leightweight Illumination model for Planetary Bodies including Direct and Diffuse Radiation

Marco Scharringhausen

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: illumination; surface properties; planetary imaging

Online: 12 December 2019 (12:32:27 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.1913.v1

Near-infrared Spectroscopy for Brain and Breast Imaging

Daniel Buckley

Subject: Engineering, Bioengineering Keywords: Near-infrared spectroscopy; Brain imaging; Breast imaging; Brain activity; Cancer; Diffuse Optical; Tomography; fNIRS

Online: 26 December 2023 (07:47:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0134.v2

Same Brain, Different Look? – the Impact of Scanner, Sequence and Preprocessing on Diffusion Imaging Outcome Parameters

Ronja Thieleking, Rui Zhang, Maria Paerisch, Kerstin Wirkner, Alfred Anwander, Frauke Beyer, Arno Villringer, A. Veronica Witte

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Diffusion Magnetic Resonance Imaging; White Matter; Fractional anisotropy; Multi-centre; Reproducibility; Imaging artefacts; Ageing

Online: 6 September 2021 (13:20:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints202101.0581.v1

Biosensors: A Sneak Peek into Plant Cell’s Immunity

Valentina Levak, Tjaša Lukan, Kristina Gruden, Anna Coll

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: genetically encoded biosensors; live spatiotemporal imaging; multiparameter imaging; plant immune response; biotic stress; crops

Online: 28 January 2021 (12:33:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202004.0297.v1

Gold Nanoparticle Mediated Multi-Modal CT Imaging of 3 Hsp70 Membrane Positive Tumors

Melanie A. Kimm, Maxim Shevtsov, Caroline Werner, Wolfgang Sievert, Zhiyuan Wu, Oliver Schoppe, Bjoern H. Menze, Ernst J. Rummeny, Roland Proksa, Olga Bystrova, Marina Martynova, Gabriele Multhoff, Stefan Stangl

Subject: Biology And Life Sciences, Biophysics Keywords: gold nanoparticle; heat shock protein 70; molecular imaging; biomarker; spectral-CT; k-edge imaging

Online: 17 April 2020 (08:42:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0118.v1

Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes

Tsviya Nayhoz, Eran A. Barnoy, Dror Fixler

Subject: Physical Sciences, Optics And Photonics Keywords: tissue-like phantoms; dual-modal imaging; fluorescence lifetime (FLT); FLT imaging (FLIM); diffusion reflection

Online: 27 October 2016 (11:52:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202103.0736.v1

Non-Invasive Evaluation of Acute Effects of Tubulin Binding Agents: A Review of Imaging Vascular Disruption in Tumors

li Liu, Devin O’Kelly, Regan Schuetze, Graham Carlson, Heling Zhou, Mary Lynn Trawick, Kevin G Pinney, Ralph P. Peter Mason

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: imaging; bioluminescence; photoacoustics; magnetic resonance imaging; vascular disrupting agents; inhib-itors of tubulin polymerization; breast cancer; kidney cancer; lung cancer; combretastatins; predictive imaging

Online: 30 March 2021 (12:54:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.1162.v2

Structural Variations of Prions and Prion-Like Proteins Associated with Neurodegeneration

Carter Sky Christensen, Wenshu Li, Danyang Yu, Henry James Li

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: prions; neurodegeneration; Alzheimer’ s disease; protein homeostasis; aggregation; prion-like proteins; amyloid beta; hyperphosphorylated tau; self replication

Online: 19 December 2023 (09:42:02 CET)

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Preprint HYPOTHESIS | doi:10.20944/preprints202105.0769.v1

On the Riemann-Hardy Conjecture for the Ramanujan Zeta-Function

Xiao-Jun Yang

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Ramanujan zeta-function; Ramanujan's tau-function; entire Ramanujan zeta-function; Ramanujan $\Xi$-function; Riemann-Hardy conjecture

Online: 31 May 2021 (12:34:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202311.0686.v1

Elasticity and Viscoelasticity Imaging Using Small Particles Exposed to an External Force

Hasan Koruk, Antonios N. Pouliopoulos

Subject: Engineering, Bioengineering Keywords: Elasticity imaging; elastography; bubble; sphere; interface; mathematical modelling; shear modulus; ultrasound sensors; viscosity; viscoelasticity imaging

Online: 10 November 2023 (07:37:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0242.v1

Single Shot 3D Incoherent Imaging Using Deterministic and Random Optical Fields with Lucy-Richardson-Rosen Algorithm

Agnes Pristy Ignatius Xavier, Francis Gracy Arockiaraj, Shivasubramanian Gopinath, Aravind Simon John Francis Rajeswary, Andra Naresh Kumar Reddy, Rashid A. Ganeev, Scott Arockia Singh M, Milling Tania S. D, Vijayakumar Anand

Subject: Physical Sciences, Optics And Photonics Keywords: coded aperture imaging; Lucy-Richardson-Rosen algorithm; computational imaging; digital ho-lography; diffractive optics; microscopy

Online: 3 August 2023 (08:26:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0109.v1

A Compact Real-time Quantitative Phase Imaging System

Tao Peng, Zeyu Ke, Shuhe Zhang, Meng Shao, Han Yang, Xiao Liu, Huijuan Zou, Zhensheng Zhong, Mincheng Zhong, Hui Shi, Shu Fang, Rongsheng Lu, Jinhua Zhou

Subject: Physical Sciences, Optics And Photonics Keywords: self-design setup; real-time imaging; GPU acceleration; quantitative phase imaging; differential phase contrast microscopy

Online: 12 April 2022 (10:19:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0090.v1

Design and Imaging of Ground-Based Multiple-Input Multiple-Output Synthetic Aperture Radar (MIMO SAR) with Non-Collinear Arrays

Cheng Hu, Jingyang Wang, Weiming Tian, Tao Zeng, Rui Wang

Subject: Engineering, Electrical And Electronic Engineering Keywords: MIMO radar; MIMO imaging; Near-field imaging; Height difference between T/R arrays; Grating lobes

Online: 15 March 2017 (00:48:12 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202106.0311.v1

A Case Report of Chronic Stress in Honey Bee Colonies Induced by Pathogens and Acaricide Residues

Elena Alonso-Prados, Amelia-Virginia González-Porto, José Luis Bernal, José Bernal, Raquel Martín-Hernández, Mariano Higes

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Honey bees; Apis mellifera; acaricides; pesticides; Toxic Unit; Varroa destructor; Nosema ceranae; bee viruses; tau-fluvalinate; coumaphos

Online: 11 June 2021 (09:55:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.0904.v1

Pancreatic Adenocarcinoma: Imaging Modalities and the Role of Artificial Intelligence

Cristian Anghel, Grasu Cristian Mugur, Denisa Andreea Anghel, Gina Ionela Rusu-Munteanu, Radu Lucian Dumitru, Ioana Gabriela Lupescu

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: pancreatic adenocarcinoma; artificial intelligence; pancreas imaging

Online: 11 January 2024 (10:14:50 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.0335.v1

Artificial Intelligence in Cancer Imaging

Ugochukwu J Jonah, Anil Parwani

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Artificial Intelligence (AI); Cancer Imaging; Diagnostics

Online: 4 January 2024 (07:35:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0608.v1

HyperVein: A Dataset for Human Vein Detection from Hyperspectral Images

Henry Ndu, Akbar Sheikh-Akbari, Jiamei Deng, Iosif Mporas

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: hyperspectral imaging; vein detection; image classification

Online: 8 December 2023 (10:38:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202308.1220.v1

Revolutionizing Biology through Neural Networks: A Deep Dive into Microscopy Image Processing and Drawings

Sehar Shah

Subject: Engineering, Bioengineering Keywords: Neural networks, Microscopy, Imaging, Tracking, Technology

Online: 17 August 2023 (09:50:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0612.v1

High Frequency of Osteophytes Detected by High Resolution Ul-Trasound at the Finger Joints of Asymptomatic Factory Workers

Mario Giulini, Ralph Brinks, Stefan Vordenbäumen, Hasan Acar, Jutta G Richter, Christian Feldhaus, Xenofon Baraliakos, Benedikt Ostendorf, Matthias Schneider, Oliver Sander, Philipp Sewerin

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Osteoarthritis; screening; prevalence; ultrasound; imaging; osteophytes

Online: 9 May 2023 (08:44:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0114.v2

A Virtual Reality System for Improved Image-based Planning of Complex Cardiac Procedures

Shujie Deng, Gavin Wheeler, Nicolas Toussaint, Lindsay Munroe, Suryava Bhattacharya, Gina Sajith, Ei Lin, Eeshar Singh, Ka Yee Kelly Chu, Saleha Kabir, Kuberan Pushparajah, John M Simpson, Julia A Schnabel, Alberto Gomez

Subject: Medicine And Pharmacology, Other Keywords: virtual reality; pre-operative imaging; echocardiography

Online: 18 August 2021 (10:02:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0220.v1

Machine-Learning for Mineral Identification and Ore Estimation From Hyperspectral Imagery in Tin-Tungsten Deposits

Agustin Lobo, Emma Garcia, Gisela Barroso, David Martí, Jose-Luis Fernandez-Turiel, Jordi Ibáñez-Insa

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: hyperspectral imaging; machine learning; spectral geology

Online: 8 June 2021 (12:22:42 CEST)

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Working Paper ARTICLE

Using MRI in Emergency Departments; Expensive Choice, But Sometimes the Optimal Means of Evaluation!

Betül Tiryaki Baştuğ

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: magnetic resonance imaging; emergency departments; utility

Online: 17 March 2020 (04:01:04 CET)

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Preprint REVIEW | doi:10.20944/preprints201811.0038.v1

Functional Connectomics in C. elegans

Elizabeth M. DiLoreto, Christopher D. Chute, Samantha Bryce, Jagan Srinivasan

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: connectomics; synapses; calcium imaging; optpgenetics; sonogenetics

Online: 2 November 2018 (09:17:37 CET)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints201810.0179.v1

Data and Code for Analyzing Performance of QHY CMOS Cameras

Hari Nandakumar, Shailesh Srivastava

Subject: Engineering, Electrical And Electronic Engineering Keywords: imaging; CMOS; camera; SNR; noise; performance

Online: 9 October 2018 (09:38:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0340.v1

Effects of Light Dosimetry in Photobleaching of The Photosensitizer (PS) and Cyanine Dye (CD) Moieties in Ps-Cd Conjudates and Its Correlation with Photodynamic Therapy (PDT) Efficacy

Nadine James, Ravindra R. Cheruku, Joseph R. Missert, Ulas Sunar, Ravindra K. Pandey

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: photodynamic therapy; photobleaching; photosensitizers; fluorescence imaging

Online: 24 May 2018 (08:32:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints201702.0037.v1

Theranostic Probes for Targeting Tumor Microenvironment: An Overview

Musafar Gani Sikkandhar, Anu Maashaa Nedumaran, Roopa Ravichandar, Satnam Singh, Induja Santhakumar, Zheng Cong Goh, Sachin Mishra, Govindaraju Archunan, Balázs Gulyás, Parasuraman Padmanabhan

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: tumor microenvironment; nanoparticle; nanotheronostics; probe; imaging

Online: 13 February 2017 (09:33:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0274.v1

Monitoring Distribution of the Therapeutic Agent Dimethyl sulfoxide (DMSO) via Solvatochromic Shift of the Albumin-Bound Indocyanine Green

Jaedu Cho, Farouk Nouizi, Chang-Seok Kim, Gultekin Gulsen

Subject: Engineering, Bioengineering Keywords: Fluorescence Imaging; Multispectral and hyperspectral imaging; Solvatochromic shift; Tunable Lasers; Spectroscopy; DMSO Sensing; Drug uptake monitoring

Online: 6 September 2023 (14:57:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.1571.v1

Heavy Metal-Based Nanoparticles as High-Performance X-Ray Computed Tomography Contrast Agents

Mohammad Yaseen Ahmad, Shuwen Liu, Tirusew Tegafaw, Abdullah Khamis Ali Al Saidi, Dejun Zhao, Ying Liu, Sung-Wook Nam, Yongmin Chang, Gang Ho Lee

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: heavy metal-based nanoparticles; X-ray attenuation; contrast agents; in vitro phantom imaging; in vivo imaging

Online: 23 August 2023 (07:54:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1183.v1

Follow‐up of Non‐Palpable Incidentalomas <1CM: Does Growth Rate Allow Distinguish between Malignant and Non‐malignant Lesions?

Michele Bertolotto, Irene Campo, Simon Freeman, Francesco Lotti, Dean Y Huang, Laurence Rocher, Lucio Dell'Atti, Massimo Valentino, Jia Cheng Yuan, Gianluca Visalli, Pietro Pavlica, Paul S Sidhu, Lorenzo Derchi

Subject: Public Health And Healthcare, Health Policy And Services Keywords: testicular incidentaloma; imaging; non‐palpable testicular tumours; imaging; Testis lesion; growth rate; incidental testicular tumour; histology

Online: 16 August 2023 (10:47:25 CEST)

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