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Preprint ARTICLE | doi:10.20944/preprints202012.0035.v1

Effects of Meditation on Mental Health and Cardiovascular Balance in Caregivers

Lourdes Díaz-Rodríguez, Keyla Vargas-Román, Juan Carlos Sanchez-Garcia, Raquel Rodríguez-Blanque, Guillermo Arturo Cañadas- De la Fuente, Emilia I. De La Fuente-Solana

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: meditation; vagal nerve activity; high-burden caregivers; mental health.

Online: 1 December 2020 (15:11:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0094.v1

Estimating the Burden Among Informal Caregivers of Stroke Survivors in East Coast Peninsular Malaysia: A Short-Term Longitudinal Study

Mohd Azmi Bin Suliman, Xin Wee Chen, Mohd Ismail Ibrahim, Kamarul Imran Musa, Nurfaten Hamzah, Iliatha Papachristou Nadal, Feisul Idzwan Mustapha, Mohd Zulkifli Abdul Rahim, Norsima Nazifah Sidek, Jafri Malin Abdullah, Sureshkumar Kamalakannan

Subject: Public Health And Healthcare, Nursing Keywords: Stroke; informal caregiver; burden; Zarit Caregiver Burden Interview; Caregiver Assessment of Function and Upset; Malaysia

Online: 8 October 2022 (05:08:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0762.v1

Burden of Care of Family Caregivers for People Diagnosed with Serious Mental Disorders in a Rural Health District in Kwa-Zulu-Natal, South Africa

Jabulile Thembelihle Ndlovu, Kebogile Elizabeth Mokwena

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Zarit Burden Interview scale; burden of care; home care giving; severe mental illness; rural setting

Online: 10 August 2023 (05:32:21 CEST)

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Jabulile Ndlovu1 and Kebogile Mokwena1, 2 1 Department of Public Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa 2 Research Chair in Substance abuse and population Mental Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa Corresponding author: jabulilendlovu5@gmail.com Abstract An estimated 6% of the world population has serious mental illness, with one in four families having a member with some form of psychiatric disorder, who are mostly cared for by their relatives within a family setting. Although caregiving in a home setting is reported to be associated with significant mental distress, the burden of such distress is rarely measured. The purpose of this study was to quantify the burden of care among family caregivers of relatives with serious mental disorders, as well as to explore possible association between the caregiver burden of care and a range of caregiver and Mental Health Care User (MHCU) variables in a rural district in Kwa-Zulu Natal, South Africa. The Zarit Burden Interview (ZBI) scale was used to collect data from 357 caregivers, and STATA 14 was used to analyze data. The ages of the sample ranged from 18 to 65, with a mean of 50.29, and the majority (86%) were female and unemployed (83%). The ZBI scores ranged from 8 to 85, with a mean of 41.59. The majority (91%) tested positive for caregiver burden of care, which ranged from mild to severe. Using the Pearson Chi-square test of association (p=0.05), variables that were significantly associated with the burden of care were clinically related (caregiver self-reported depression, MHCU diagnosis, recent relapse of the MHCU), socio-economic (caregiver family monthly income, MHCU disability grant status and MHCU employment status) and socio-demographic (MHCU gender and MHCU level of education). The prevalence of burden of care is high and severe, and scarcity of resources in families and communities contribute to the high burden of care in these rural communities.

Preprint ARTICLE | doi:10.20944/preprints202312.2199.v1

Hope Mediates Stress to Reduce Burden in Family Caregivers of Persons with Dementia

Jocelyn Shealy McGee, Edward C. Polson, Dennis Myers, Angela McClellan, Rebecca Meraz, Weiming Ke, Holly Carlson Zhao

Subject: Public Health And Healthcare, Other Keywords: Alzheimer's disease; dementia; cargiving; burden; hope; positive psychology; positive aspects of caregiving; stress; coping

Online: 28 December 2023 (14:36:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0694.v1

Caregivers’ burden experience: a comparison between Parkinson's Disease, Multiple System Atrophy and Amyotrophic Lateral Sclerosis

Luna Carpinelli, Giulia Savarese, Claudio Russo, Giovanna Stornaiuolo, Ettore Luisi, Francesca Pellegrino, Monica Mollo, Antonella Toriello, Paolo Barone, Maria Teresa Pellecchia

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Caregivers’ burden; Quality of Life; Neurological diseases; Parkinson’ s Disease; Multiple System Atrophy; Amyotrophic Lateral Sclerosis

Online: 12 February 2024 (13:28:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0024.v1

The Critical Issues for Patients and Caregivers in Neuro-Oncology During Covid-19 Pandemic: What We Have Learnt by an Observational Study.

Elena Anghileri, Irene Tramacere, Sara Morlino, Catia Leuzzi, Lorena Pereja Gutierrez, Saba Motta, Antonio Silvani, Francesca Romana Berrini

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Anxiety; Caregivers; Caregiver Burden; Communication; COVID-19; (Brain) Neoplasms; Pandemics; Perception; Psycho-Oncology; Quality of Life

Online: 1 April 2024 (10:08:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0293.v1

Safety and Efficacy of Adjunctive Catheter-Directed Thrombolysis During Primary PCI for ST-segment Elevation Myocardial Infarction With High Thrombus Burden

Satsuki Noma, Hideki Miyachi, Isamu Fukuizumi, Junya Matsuda, Hideto Sangen, Yoshiaki Kubota, Yoichi Imori, Yoshiyuki Saiki, Yusuke Hosokawa, Shuhei Tara, Yukichi Tokita, Koichi Akutsu, Wataru Shimizu, Takeshi Yamamoto, Hitoshi Takano

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: high coronary thrombus burden; tissue plasminogen activator; catheter-directed thrombolysis

Online: 20 October 2021 (12:53:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0038.v1

The Lifetime Expenditure in People with Keratoconus in Saudi Arabia

Saleha K. Al-Atawi, Ali Alghamdi, Khaled Alzahrani

Subject: Medicine And Pharmacology, Ophthalmology Keywords: keratoconus; lifetime expenditure; economic burden; Keratoconus Economic Burden Questionnaire

Online: 2 March 2023 (08:48:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0210.v1

Improving the Cognitive Impact of Migraine: A Real-World Study on the Ability to Concentrate

Isabel Pavão Martins, Beatriz Nunes Vicente, João Bajouco Nobre, Mariana Dias da Costa, Filipa Dourado Sotero

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: cognitive impact; chronic migraine; migraine burden

Online: 3 January 2024 (09:43:32 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202203.0014.v1

Body Plan Identity: A Mechanistic Model

James DiFrisco, Gunter Wagner

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: body plan; archetype; burden; generative entrenchment

Online: 1 March 2022 (10:17:43 CET)

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Preprint REVIEW | doi:10.20944/preprints202207.0315.v1

Protocol of the Dual Burden of Animal and Human Zoonoses: A Systematic Review

Liz P. Noguera Z., Duriya Charypkhan, Simon Rüegg, Sonja Hartnack, Paul Torgerson

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: protocol; review; zoonosis; zoonotic diseases; infectious diseases; burden of diseases; DALY; zDALY; monetary burden; animal losses

Online: 21 July 2022 (08:12:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0123.v1

Active Case Finding for Tuberculosis through TOUCH Agents in Selected High TB Burden Wards of Kolkata, India: A Mixed-methods Study on Outcomes and Implementation Challenges

Abhijit Dey, Pruthu Thekkur, Ayan Ghosh, Tanusree Dasgupta, Soumyajyoti Bandopadhyay, Arista Lahiri, Chidananda SV, Milan Dinda, Vivek Sharma, Namita Dimari, Dibyendu Chatterjee, Isita Roy, Anuradha Chanda, Parthiban Shanmugam, Brojokishore Saha, Sanghamitra Ghosh, Sharath Nagaraja

Subject: Medicine And Pharmacology, Tropical Medicine Keywords: Active case findings; Tuberculosis; TOUCH Agent; High TB burden area; TB Surveillance; 4S Screening; THALI Project; SORT IT; Operational Research

Online: 11 September 2019 (13:30:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.2025.v1

Effects of Premature Ventrıcular Complex Burden on Left Ventrıcular Global Longıtudınal Straın in Patıents Wıthout Structural Heart Dısease

Sukru Arslan, H. Ozan Arabaci, Muhammed Furkan Deniz, Mehmet Emin Gokce, Seyma Arslan, Veysel Oktay, Mustafa Yildiz, Isil Uzunhasan

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: idiopathic PVC; global longitudinal strain; PVC burden

Online: 29 January 2024 (13:05:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0861.v1

The Economic Burden of Alopecia Areata in Romania

Stefan Strilciuc, Rodica Olteanu, Rozalina Lăpădatu, Diana-Alecsandra Grad, Cristian Vlădescu, Alin Codruț Nicolescu

Subject: Medicine And Pharmacology, Dermatology Keywords: alopecia areata, cost of illness, economic burden

Online: 11 January 2024 (10:29:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0242.v1

Assessing Global Frailty Scores: Development of a Global Burden of Disease-Frailty Index (GBD-FI)

Mark O’Donovan, Duygu Sezgin, Zubair Kabir, Aaron Liew, Rónán O’Caoimh

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Frailty; Public Health; Global Burden of Disease

Online: 11 July 2020 (16:16:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0053.v1

Estimating the Burden of Serious Fungal Infections in Uruguay

Marina Macedo-Viñas, David W. Denning

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: epidemiology of fungal infections; infection burden; Uruguay

Online: 6 February 2018 (06:52:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1139.v1

How Possible Is the Elimination of Viral Hepatitis? An Analysis Based on the Global Burden of Disease from Hepatitis B and C, 1990–2019

Nelson Alvis-Guzman, Nelson J. Alvis-Zakzuk, Fernando De la Hoz Restrepo

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Hepatitis C; Elimination; Global Burden of Disease; Mortality

Online: 18 October 2023 (17:35:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0011.v1

Double Burden of Malnutrition (DBM) and Anaemia under the Same Roof: A Bangladesh Perspective

Sumaiya Mamun, Christopher Guy Nicholas Mascie-Taylor

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: double burden of malnutrition; anaemia; undernutrition; overweight; obesity

Online: 3 September 2018 (05:45:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201806.0392.v1

Amani Zidan, Ahmed Awaisu, Maguy El-Hajj, Samya Al-Abdulla, Dianne Figueroa, Nadir Kheir

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Medication-related burden; Questionnaire; chronic disease conditions; adherence

Online: 25 June 2018 (14:35:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0584.v1

Caregiver Burden in Small Animal Clinics: A Comparative Analysis of Dermatological and Oncological Cases

Pollyana T. R. F. Silva, Fernanda M. Coura, Adriane P. Costa-Val

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: burden of care; cat; dog; human-animal interaction; owner

Online: 8 December 2023 (10:25:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.0819.v1

Evaluate the Impact of the Long-Term Care Insurance (LTCI) System on Older Adults in Japan

Chuhan Miao, Beilei Li, Jianxun He

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Long-term care insurance; Japan; Older adults; Financial burden; Population

Online: 14 March 2024 (11:11:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.2007.v1

Τhe Cost and the Value of Stroke Care in Greece: Results from the SUN4P Study

Olga Ch. Siskou, Petros Galanis, Olympia Konstantakopoulou, Panagiotis Stafylas, Iliana Karagouni, Evangelos Tsampalas, Daphne Garefou, Helen Alexopoulou, Anasstasia Gamvroula, Maria Lypiridou, Ioannis Kalliotzakis, Anastasia Fragkoulaki, Aspasia Kouridaki, Argyro Tountopoulou, Ioanna Kouzi, Sofia Vassilopoulou, Efstathios Manios, Georgios Mavraganis, Anastasia Vemmou, Efstathia Karagkiozi, Christos Savopoulos, Grigorios George Dimas, Athina Myrou, Haralampos Milionis, Georgios Siopis, Xara Evaggelou, Athanase D. Protogerou, Stamatia Samara, Asteria Karapiperi, Nikolaos Kakaletsis, George Papastefanatos, Stefanos Papastefanatos, Panayota Sourtzi, George Ntaios, Konstantinos Vemmos, Eleni Korompoki, Daphne Kaitelidou

Subject: Public Health And Healthcare, Health Policy And Services Keywords: stroke; cost; burden; direct healthcare cost; loss of productivity; QALY

Online: 31 July 2023 (05:04:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1613.v1

Inhibition of Trichinella spiralis Membrane‐Associated Progesterone Receptor (MAPR) Results in the Reduction of Worm Burden

Muhammad Tahir Aleem, Zhaohai Wen, Zhengqing Yu, Cheng Chen, Mingmin Lu, Lixin Xu, Xiaokai Song, Xiangrui Li, Ruofeng Yan

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: inhibitory effect; knockdown; rTs‐MAPRC2‐Ab; Trichinella spiralis; worm burden

Online: 24 July 2023 (11:47:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0702.v1

The Burden of Air Pollution: A Perspective on Global Health Inequalities

Agnieszka Jakubowska

Subject: Environmental And Earth Sciences, Pollution Keywords: air pollution; disease burden; YLLs; YLDs; health inequalities; productivity loss

Online: 10 May 2023 (08:04:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.1273.v1

Quality of Life among Parents of Children and Adolescents with Diabetes: A Literature Review

Paraskevi Theofilou, Dimitrios Vlastos

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Diabetes; parents; children; adolescents; quality of life; stress; family burden

Online: 30 April 2023 (10:11:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0022.v1

90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil

Daniela Debone, Mariana da Costa, Simone Miraglia

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: COVID-19; Air pollution; Air quality; Health effects; Economic burden

Online: 2 August 2020 (11:59:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1541.v1

National Burden and Trends for 29 Groups of Cancer in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Saul A. Beltran-Ontiveros, Jose A. Contreras-Gutierrez, Erik Lizarraga-Verdugo, Erick P Gutierrez-Grijalva, Kenia Lopez-Lopez, Emilio H. Lora-Fierro, Miguel A. Trujillo-Rojas, Jose M. Moreno-Ortiz, Diana L. Cardoso-Angulo, Emir Leal-Leon, Jose R. Zatarain-Lopez, Hector M. Cuen-Diaz, Marisol Montoya-Moreno, Brisceyda Arce-Bojorquez, Jose L. Rochin-Teran, Daniel E. Cuen-Lazcano, Victor A. Contreras-Rodriguez, Ricardo Lascurain, Liliana Carmona-Aparicio, Elvia Coballase-Urrutia, Francisco Gallardo-Vera, Daniel Diaz

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Burden of disease; Cancer epidemiology; Cancer mortality, Malignant neoplasm; Public health

Online: 23 November 2023 (14:05:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1850.v1

Deepening Depression in Women Balancing Work-Life and Caregiving during the COVID-19 Pandemic: Findings of Gender-Specific Face-to-Face Street Interviews Conducted in Italy

Laura Giusti, Silvia Mammarella, Sasha Del Vecchio, Anna Salza, Massimo Casacchia, Rita Roncone

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Women; depression; family burden; family functioning; pandemic COVID-19; collective traumas

Online: 27 September 2023 (08:33:42 CEST)

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Purpose: This study investigated the impact of the COVID-19 pandemic on mental health, quality of life, and family functioning in a sample of the general female population, exploring difficulties encountered in managing family and work responsibilities and burden of care when taking care of a loved one. The study was moreover aimed at investigating factors capable of influencing severe depressive symptomatology in the context of socio-demographics, traumatic events, individual vulnerability, and family functioning. Method: During a weekend devoted to Mental Health initiatives (October 8-10, 2021), 211 women were interviewed (47% exposed to the 2009 L’Aquila earthquake). Results: More than 50% of the sample reported a higher complexity in managing their lives during the COVID-19 pandemic compared to their previous routine, with no statistically significant differences between working women and non-workers, although the latter obtained higher scores for depressive symptomatology and poorer quality of life. Compared to non-caregivers, women caregivers (22.3%) in charge of the care of loved ones affected by physical (10.9%) or psychiatric disabilities (11.4%) complained of a poorer quality of life, with those caring for people affected by mental disorders seeming to experience a more significant worsening. Approximately 20% of the total sample reported severe depressive symptomatology. Previous access to mental health services (O.R. 10.923), low level of education (O.R. 5.410) and difficulties in management of their everyday lives during the COVID-19 pandemic (O.R. 3.598) were found to be the main variables predictive of severe depressive psychopathology. Old age, good problem-solving skills and ability to pursue personal goals were identified as protective factors. Conclusions: The COVID-19 pandemic underlined the need for support for emotionally vulnerable women with pre-existing mental health conditions, partly reflecting the cumulative effects of traumas.

Preprint ARTICLE | doi:10.20944/preprints201909.0296.v1

BODE Index Correlated with Charlson Comorbidity Index and Medical Burden in COPD

Li Chin Ling, Lin Mei-Hsin, Tsai Yuh-Chyn, Chen Pei-Shiuan, Shen Lien-Shi, Kuo Ho-Chang, Liu Shih-Feng

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: chronic obstructive pulmonary disease; bode index; charlson comorbidity index; medical burden

Online: 26 September 2019 (09:58:37 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1863.v1

Long-Term Outcomes and Prognosis of Patients with Myocardial Infarction During Covid Pandemic

Marius Rus, Adriana Ioana Ardelean, Ana Maria Jurcau, Felicia Liana Andronie-Cioara, Paula Marian, Oana Lilliana Pobirci, Veronica Huplea, Alina Stanca Osiceanu, Adrian Gheorghe Osiceanu, Simina Crisan, Georgiana Carmen Filimon

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: COVID 19; myocardial infarction; cardiovascular burden; long-term outcomes; acute coronary syndrome

Online: 27 September 2023 (11:29:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0123.v1

The Prevalence of Periodontal Diseases in Portugal and Correspondent Digital National Awareness: Analysis of Data from Global Burden of Disease, Directorate-General of Health and Google Trends for the Period 2004-2017

Vanessa Machado, João Botelho, João Albernaz Neves, Luís Proença, Ricardo Alves, Maria Alzira Cavacas, João Rua, Ana Delgado, José João Mendes

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Medical Illiteracy, Public Awareness, Periodontal Diseases, Global Burden of Disease, Google Trends

Online: 13 February 2019 (15:54:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0030.v2

Using the Job Burden-Capital Model of Occupational Stress to Predict Depression and Well-Being among Electronic Manufacturing Service Employees in China

Chao Wang, Shuang Li, Tao Li, Shanfa Yu, Junming Dai, Xiaoman Liu, Xiaojun Zhu, Yuqing Ji, Jin Wang

Subject: Social Sciences, Psychology Keywords: occupational stress; job burden-capital model; structural equation model; depression; well-being

Online: 4 August 2016 (12:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0830.v2

The Economic Burden of Atopic Dermatitis in Romania: A Broad Perspective

Alin Codrut Nicolescu, Stefan Strilciuc, Rozalina Lapadatu, Diana Alecsandra Grad, Cristian Vladescu, Rodica Olteanu

Subject: Medicine And Pharmacology, Dermatology Keywords: Atopic dermatitis, economic burden of disease, cost of illness

Online: 16 January 2024 (10:29:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1343.v1

Depressive Disorders and EU Labour Resources – the Problem of Lost Productivity in Highly Developed Economies

Agnieszka Jakubowska

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: indirect costs of depression; burden of disease; lost productivity; inequality in the EU

Online: 18 December 2023 (15:14:46 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202103.0113.v1

Viewpoint: The Current Advances and Future Optimization of Blood-based Tumor Mutation Burden as a Biomarker for Cancer Immunotherapy

Anlin Li

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: blood-based mutation burden (bTMB); cancer immunotherapy; immune checkpoint inhibitor (ICI); biomarker; mutation

Online: 2 March 2021 (21:45:40 CET)

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Preprint REVIEW | doi:10.20944/preprints202101.0184.v1

Multi-pathogen Infections and Alzheimer’s Disease

Jiri Damborsky, Dana Vigasova, Michal Nemergut, Barbora Liskova

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Alzheimer’s Disease; antibacterial; anti-biofilm; antifungal; antiviral; bacteria; infectious burden; parasites; pathogens; viruses

Online: 11 January 2021 (11:28:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201901.0060.v1

Global Need for Physical Rehabilitation: Systematic Analysis from the Global Burden of Disease Study 2017

Tiago S. Jesus, Michel D. Landry, Helen Hoenig

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: rehabilitation; global health; disability; global burden of disease; health services needs and demand

Online: 8 January 2019 (10:52:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.1395.v1

Sex, Age, and Regional Disparities in the Burden of Asthma in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Ana Lopez-Bago, Ricardo Lascurain, Pavel E. Hernandez-Carreño, Francisco Gallardo-Vera, Jesus Argueta-Donohue, Francisco Jimenez-Trejo, David A. Fuentes-Zavaleta, Saul A. Beltran-Ontiveros, Delia M. Becerril-Camacho, Victor A. Contreras-Rodriguez, Daniel Diaz

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Allergic diseases; Atopic march; Burden of disease; Chronic respiratory diseases; DALYs; Epidemiology; Incidence; Prevalence

Online: 21 June 2023 (08:52:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0084.v1

Incidence, Mortality, Disability-Adjusted Life Years, and Trends of Prostate Cancer in Mexico from 2000 to 2019: Results from the Global Burden of Disease Study 2019

Saul A. Beltran-Ontiveros, Martha A. Fernandez-Galindo, Jose M. Moreno-Ortiz, Jose A. Contreras-Gutierrez, Jesus Madueña-Molina, Elyakim Arambula-Meraz, Emir Leal-Leon, Delia M. Becerril-Camacho, Veronica J. Picos-Cardenas, Carla Angulo-Rojo, Diana Z. Velazquez, Francisco Jimenez-Trejo, Francisco Gallardo-Vera, Daniel Diaz

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Age-standardized rate; Burden of disease; Cancer epidemiology; Malign neoplasm; Sociodemographic index; Subnational heterogeneity

Online: 6 May 2022 (14:47:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0004.v1

N1-Methyladenosine (m1A) Regulator-Mediated Methylation Modification Modes and Tumor Microenvironment Infiltration Characteristics in Head and Neck Squamous Cell Carcinomas

Yan-Dong Miao, Lin-Jie Mu, Xiao-Long Tang, Jiang-Tao Wang, Jing-Jing Wu, Yong-Gang Chen, Deng-Hai Mi

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: m1A; Tumor microenvironment; PD-1/PD-L1; CTLA-4; Tumor Mutation Burden; Bioinformatics Analysis

Online: 1 November 2021 (10:39:51 CET)

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Preprint REVIEW | doi:10.20944/preprints202305.1239.v1

Immune Checkpoint Blockade and Biomarkers of Response in Lymphoma: A Case-Illustrated Narrative Review

Sarah Perdikis-Prati, Semira Sheikh, Bouroumeau Antonin, Noémie Lang

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Hodgkin lymphoma; non-Hodgkin lymphoma; PD1 / PD-L1 checkpoint inhibitors; tumor mutational burden; predictive biomarkers

Online: 17 May 2023 (10:52:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0590.v1

Estimates of Cancer Mortality Attributable to Carcinogenic Infections in Italy

Pietro Ferrara, Sara Conti, Fernando Agüero, Luciana Albano, Cristina Masuet-Aumatell, Josep Maria Ramon-Torrell, Lorenzo Giovanni Mantovani

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: burden of cancer mortality; cancer epidemiology; cancer etiology; cancer prevention; carcinogenic infections; modifiable risk factors

Online: 28 October 2020 (12:13:01 CET)

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Preprint REVIEW | doi:10.20944/preprints202007.0389.v1

Demanding of Lassa Fever: Reducing its Risk as an Infectious Disease

Abdullahi Tunde Aborode, Victor Adegbile Adesewa, Oni Ebenezer Ayomide, Samuel Ogunsola Olarenwaju

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Lassa Fever; Virus; Infectious Disease; Hazard; West Africa; Health Care; Epidemiology; Epidemic; Measures; Burden; Management

Online: 17 July 2020 (15:19:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1063.v1

Design and Implementation of Automatic Cooling Case Based on High-Power and High-Density Power Supply Array

Zerui Chen, Hangwei Feng, Guoguang Zhang, Chong Yang

Subject: Engineering, Electrical And Electronic Engineering Keywords: thermal design; miniaturization; high power; high density; automation

Online: 18 September 2023 (05:22:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2058.v1

Super-high Magnification Dermoscopy in 190 Clinically Atypical Pigmented Lesions

Vittoria Cioppa, Giulio Cortonesi, Linda Tognetti, Jean Luc Perrot, Renato Rossi, Matteo Gnone, Alessandra Cartocci, Pietro Rubegni, Elisa Cinotti

Subject: Medicine And Pharmacology, Dermatology Keywords: Dermoscopy; high magnification; super-high magnification; keratinocyte; melanocyte; melanoma.

Online: 30 May 2023 (06:04:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0068.v1

Effects of Chitosan on the AsA-GSH Cycle of Strawberry Seedlings Under High-temperature and High-light Stress

Erting Fu, Yuzheng Zhang, Huiling Li, Xiaozhe Wang, Hanxiao Zhang, Wei Xiao, Ling Li, Xiude Chen

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: strawberry; high-temperature and high-light; AsA-GSH cycle

Online: 3 February 2023 (09:54:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0158.v1

Permeability evolution of pyrolytically-fractured oil shale under in situ conditions

Fuke Dong, Zijun Feng, Dong Yang, Yangsheng Zhao, Dereck Elsworth

Subject: Engineering, Energy And Fuel Technology Keywords: Oil shale; Permeability; Pyrolysis; High temperature and high pressure

Online: 10 September 2018 (09:14:56 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202007.0633.v1

Community-Based Household Survey to Identify Disability Burden and Health-Related Quality of Life Following Road Traffic Accidents in Ujjain, India

Aditya Mathur, Love Mehra, Ashish Pathak

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Children; adolescents; post-road traffic accidents; EQ-5D-5L; disability burden; health-related quality of life

Online: 26 July 2020 (03:11:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1917.v1

Waste Activated Sludge-High Rate (WASHR) Treatment Process: A Novel, Economically Viable and Environmentally Sustainable Method to Co-treat High-Strength Wastewaters at Municipal Wastewater Treatment Plants

Mehrab Mehrvar, Melody Blythe Johnson

Subject: Engineering, Bioengineering Keywords: WASHR; co-treatment; high-rate treatment; high-strength wastewater; waste activated sludge-high rate; winery wastewater

Online: 28 July 2023 (13:02:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0024.v1

Association between Serum High-Density Lipoprotein Cholesterol and Hypertension: Results of Kanagawa Investigation of Total Checkup Data from the National Database-9 (Kitchen-9)

Kei Nakajima, Manami Igata, Kotone Tanaka, Ryoko Higuchi, Kaori Mizusawa, Teiji Nakamura

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: high-density lipoprotein cholesterol; hypertension; blood pressure; low high-density lipoprotein cholesterol; extremely high high-density lipoprotein cholesterol; body mass index; big data

Online: 1 July 2021 (11:53:04 CEST)

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Preprint REVIEW | doi:10.20944/preprints202109.0288.v1

Role of Diet in Modification of Gut Microbiota in Obesity: Review of Recent Literature

Umama Khan, S M Niazur Rahman, Nazmun Nahar Alam

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Diet; Obesity; Gut microbes; High-fiber diet; High fat diet

Online: 16 September 2021 (13:50:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0098.v1

Multiscale Mapping of the Salt Marshes Using Sentinel-2, Dove and UAV Imagery in the Bay of Mont-Saint-Michel

Antoine Collin, Dorothée James, Antoine Mury, Mathilde Letard, Thomas Houet, Hélène Gloria, Eric Feunteun

Subject: Biology And Life Sciences, Biophysics Keywords: spatiotemporal analysis; high to ultra high spatial resolution; high to very high temporal resolution; NDVI; NIR; neural network modelling, Bay of Mont-Saint-Michel

Online: 4 November 2021 (09:35:50 CET)

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Preprint REVIEW | doi:10.20944/preprints202007.0489.v1

Putting the Squeeze on Molecule-Based Magnets: Exploiting Pressure to Develop Magneto-Structural Correlations in Paramagnetic Coordination Compounds

Euan Brechin, Alvaro Etcheverry-Berrios, Simon Parsons, Konstantin Kamenev, Michael Probert, Stephen Moggach, Mark Murrie

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: High pressure X-ray crystallography; high pressure magnetometry; high pressure absorption spectroscopy; high pressure EPR; molecule-based magnets; single-molecule magnets; single-ion magnets

Online: 21 July 2020 (12:48:58 CEST)

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The cornerstone of molecular magnetism is a detailed understanding of the relationship between structure and magnetic behaviour, i.e. the development of magneto-structural correlations. Traditionally, the synthetic chemist approaches this challenge by making multiple compounds that share a similar magnetic core but differ in peripheral ligation. Changes in the ligand framework induce changes in the bond angles and distances around the metal ions which are manifested in changes to magnetic susceptibility and magnetisation data. This approach requires the synthesis of series of different ligands and assumes that the chemical/electronic nature of the ligands and their coordination to the metal, the nature and number of counter ions and how they are positioned in the crystal lattice, and the molecular and crystallographic symmetry have no effect on the measured magnetic properties. In short, the assumption is that everything outwith the magnetic core is innocent, which is a huge oversimplification. The ideal scenario would be to have the same complex available in multiple structural conformations, and this is something that can be achieved through the application of external hydrostatic pressure, correlating structural changes observed through high pressure single crystal X-ray crystallography with changes observed in high pressure magnetometry, in tandem with high pressure inelastic neutron scattering (INS), high pressure electron paramagnetic resonance (EPR) spectroscopy and high pressure absorption/emission/Raman spectroscopy. In this review, which summarises our work in this area over the last 15 years, we show that the application of pressure to molecule-based magnets can (reversibly): (1) lead to changes in bond angles, distances and Jahn-Teller orientations; (2) break and form bonds; (3) induce polymerisation/depolymerisation; (4) enforce multiple phase transitions; (5) instigate piezochromism; (6) change the magnitude and sign of pairwise exchange interactions and magnetic anisotropy and (7) lead to significant increases in magnetic ordering temperatures.

Preprint ARTICLE | doi:10.20944/preprints202212.0174.v1

Possibilities of Rock Processing with a High-pressure Abrasive Water Jet with an Aspect Terms to Minimising Energy Consumption

Grzegorz Chomka, Maciej Kasperowicz, Jarosław Chodór, Jerzy Chudy, Leon Kukiełka

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: high-pressure water jet; high-pressure abrasive water- jet; rock processing

Online: 9 December 2022 (09:22:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0042.v1

Fundamental Study on the Development of Sprayed High Performance Fiber Reinforced Cementitious Composites for Impact-Blast Resistant

Yun-Wang Choi, Byung-Keol Choi, Sung-Rok Oh, Man-Seok Park

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: high volume fly ash, high fluidity concrete, early strength, field application

Online: 13 February 2017 (11:44:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0218.v1

Global Incidence and Mortality Patterns and Forecast of Pedestrian Road Traffic Injuries by Socio-Demographic Index Findings from the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study

Moien A. B. Khan, Michal Grivna, Javaid Nauman, Elpidoforos S. Soteriades, Arif Alper Cevik, Muhammad Jawad Hashim, Romona Govender, Salma Rashid Al Azeezi

Subject: Medicine And Pharmacology, Other Keywords: road traffic injuries; public safety; global burden; economic loss; health policy; health care system; health indicators; injury prevention

Online: 16 February 2020 (13:48:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0545.v1

Accurate and Efficient Explicit Approximations of the Colebrook Flow Friction Equation Based on Wright-Omega Function

Dejan Brkić, Pavel Praks

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Colebrook equation; hydraulic resistance; Lambert W-function; Wright Ω-function; explicit approximations; computational burden; turbulent flow; friction factor

Online: 23 October 2018 (16:28:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0187.v1

One-Log Call Iterative Solution of the Colebrook Equation for Flow Friction Based on Padé Polynomials

Pavel Praks, Dejan Brkić

Subject: Engineering, Control And Systems Engineering Keywords: Colebrook equation; Colebrook-White; flow friction; iterative procedure; logarithms; Padé polynomials; hydraulic resistances; turbulent flow; pipes; computational burden

Online: 11 July 2018 (03:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0575.v1

Effects of Silicon Content on Oxidation at 1000°C of Aisi 1045, Aisi 5160 and Aisi 9254 Steels.

Guilherme Maranhão Costa, Lioudmila Aleksandrovna Matlakhova, Sergio Neves Monteiro

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: high-temperature; silicon; oxidation

Online: 8 December 2023 (10:14:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0586.v1

Surfactant-polymer Flooding: Chemical-formula Design and Evaluation for High-temperature High-salinity Qinghai Gasi Reservoir

Jinlong Sun, Yifeng Liu, Xiuyu Zhu, Futang Hu, Yuanyuan Wang, Xiaoling Yi, Zhuoyan Zhu, Weidong Liu, Youyi Zhu, Qingfeng Hou

Subject: Engineering, Energy And Fuel Technology Keywords: chemical flooding; surfactant; polymer; enhanced oil recovery; high-temperature high-salinity reservoir

Online: 8 April 2024 (17:19:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0202.v1

Research on Four-Phase Interleaved Step-Up DC/DC Converter for Photovoltaic Energy Storage System

Xiaogang Wu, Boyang Yu, Jiuyu Du, Wenwen Shi

Subject: Engineering, Electrical And Electronic Engineering Keywords: DC-DC converter; photovoltaic energy storage system; high voltage gain; high efficiency

Online: 17 April 2019 (11:40:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0731.v1

Seismic Performance Assessment of Composite Frame – High-Strength Steel Plate Wall Core Tube Resilient Structure System

Lei Zhang, Cuikun Wang, Caihua Chen, Mingzhe Cui

Subject: Engineering, Civil Engineering Keywords: high-performance structural system; high strength steel; ultra-high strength concrete; double steel plate concrete composite shear wall; seismic resilience assessment

Online: 11 December 2023 (15:58:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0209.v1

Estimating the influencing factors of Gas-Water Relative Permeability in Condensate Gas Reservoirs under High-Temperature and High-Pressure Conditions

Shuheng Cui, QiLin Wu, Zixuan Wang

Subject: Engineering, Energy And Fuel Technology Keywords: gas-water relative permeability; high temperature; high pressure; condensate gas reservoir; influencing factors

Online: 5 March 2024 (10:57:23 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202311.0655.v1

High Repetition Frequency Solid-State Green Laser with Large Stable Area for Water Jet Guided

Ji Wang, Wenwu Zhang

Subject: Engineering, Mechanical Engineering Keywords: high stable; stable zone; water jet guided laser; green laser; high repetition frequency

Online: 9 November 2023 (15:11:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0240.v1

Study of Hybrid Transmission HVAC/HVDC by Particle Swarm Optimization (PSO)

Yulianta Siregar, Credo Maestro Hasianta Pardede

Subject: Engineering, Electrical And Electronic Engineering Keywords: high voltage alternating current; high voltage direct current; particle swarm optimization; power losses

Online: 16 September 2022 (07:52:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0070.v1

Deploying Efficiently Modern Applications on Cloud

Damiano Perri, Marco Simonetti, Osvaldo Gervasi

Subject: Computer Science And Mathematics, Information Systems Keywords: Web app; Cloud computing; High Availability; High performance computing; Docker container; Horizontal Scaling

Online: 6 January 2022 (10:33:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.1099.v1

High-Crystallinity BiOCl Nanosheets As Efficient Photocatalysts for Norfloxacin Antibiotics Degradation

Mingxia Li, Bo Wang, Zhenzi Li

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: photocatalysis; BiOCl; nanosheets; high-crystallinity

Online: 16 May 2023 (05:20:10 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202207.0271.v1

Ultra-High-Performance Fiber-Reinforced Concrete: Applications

Shaker Qaidi

Subject: Engineering, Civil Engineering Keywords: Ultra-High-Performance Concrete; applications

Online: 18 July 2022 (11:07:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0088.v1

Numerical Approach in Superconductivity: An Advanced Study

Valeriy Kizka

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: High-temperature superconductivity; critical temperature

Online: 6 January 2022 (12:36:26 CET)

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Preprint REVIEW | doi:10.20944/preprints201808.0174.v1

Oral Biofilms: Development, Control and Analysis

Daniela Berger, Aviva Rakamimova, Andrew Pollack, Zvi Loewy

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: biofilm; antimicrobial; high-throughput analysis

Online: 9 August 2018 (00:20:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0252.v1

An Innovative Bidirectional DC-AC Converter to Improve Power Quality in a Grid-Connected Microgrid

Sebastien Bissey, Sebastien Jacques, Cedric Reymond, Jean-Charles Le Bunetel

Subject: Engineering, Electrical And Electronic Engineering Keywords: Smart home electricity management system; bidirectional DC-AC converter; high power quality; high efficiency.

Online: 14 July 2018 (20:25:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0515.v1

Modeling Pulsed High-Power Spikes to Drive Piezoelectric Broadband Transducers Improving SNR in Ultrasonic Imaging & NDE

Antonio Ramos, Abelardo Ruiz, Enrique Riera

Subject: Computer Science And Mathematics, Mathematics Keywords: efficient ultrasonic transceivers, broadband piezoelectric transducers, industrial NDE, medical imaging, pulsed high-power spikes, HV capacitive-discharge pulsers, high-current driving, high dynamic range.

Online: 22 March 2021 (11:16:39 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.1521.v1

Cardiovascular Benefits of High-Intensity Interval Training in Patients with Hypertension: A Systematic Review

Priyanka Yelavarthy, Binay Panjiyar, Pragathi Yelavarthy, Sriharsha Lankala

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: hypertension; cardiac complications; high-intensity interval training in hypertension; high blood pressure; hypertension; cardiovascular diseases

Online: 19 January 2024 (16:02:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0543.v1

Research and Application of a High-pressure, Large-flow and High-water-based Mining Digitally Controlled Unloading Valve

Xiaochun Zhang, Jiyun Zhao

Subject: Engineering, Control And Systems Engineering Keywords: mining unloading valve; high pressure; large flow; high-water-based fluid; digitally controlled unloading valve

Online: 8 September 2023 (05:09:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1004.v1

Cuban Policosanol (Raydel®) Exhibited Potent Anti-inflammatory Activity in the Liver and Protection of the Ovary and Testis with an Improvement of Blood Lipid Profile by 12 Weeks Supplementation in Hyperlipidemic Zebrafish: Comparison Study of Efficacy with Three Chinese Policosanols

Kyung-Hyun Cho, Ji-Eun Kim, Seung Hee Baek

Subject: Biology And Life Sciences, Life Sciences Keywords: Policosanol; high cholesterol diet; high-density lipoproteins; apoA-I; inflammation; interleukin-6; liver; testis; ovary

Online: 14 July 2023 (09:27:04 CEST)

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Although many policosanols from different sources, such as sugar cane, rice bran, and insects, have been marketed worldwide, there has been no comparative study of the in vivo efficacy using a hyperlipidemic animal model. This study compared the efficacy of treating dyslipidemia with four different policosanols, including one sugar cane wax alcohol from Cuba (Raydel®) and three policosanols from China (Xi’an Natural sugar cane, Xi’an Realin sugar cane, and Shaanxi rice bran) in hyperlipidemic zebrafish. After 12 weeks of consumption of each policosanol (final 0.1% in diet, wt/wt) and high cholesterol diet (HCD, final 4%, wt/wt) in a tetrabit, the Raydel policosanol group and Xi’an Natural policosanol group showed the highest survivability of approximately 81%, whereas the Xi’an Realin policosanol group and Shaanxi policosanol group showed 57% and 67% survivability, respectively. Among five HCD groups, the Raydel policosanol group showed the lowest serum total cholesterol (TC, p<0.001 versus HCD control) and triglyceride (TG, p<0.001 versus HCD control) with the highest percentage of high-density lipoproteins (HDL)-C in TC. The Raydel policosanol group also showed the lowest serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels with the least infiltration of inflammatory cells and interleukin-6 production in hepatocytes. In the ovary, the Raydel policosanol group also showed the highest contents of mature vitellogenic oocytes with the lowest production of reactive oxygen species and cellular apoptosis in ovarian cells. In the testis, the Raydel policosanol group also showed the healthiest morphology for spermatogenesis with the least interstitial area and reactive oxygen species (ROS) production in testicular cells. In conclusion, 12 weeks of Raydel policosanol consumption resulted in remarkable improvement of the blood lipid profile, amelioration of inflammation in the liver, and enhancement of the cell morphology in the ovary and testis with the highest survivability under the HCD.

Preprint ARTICLE | doi:10.20944/preprints202007.0120.v1

Microstructure and Composition Evolution of a Fused Slurry Silicide Coating on MoNbTaTiW Refractory High-entropy Alloy in High-temperature Oxidation Environment

Jiesheng Han, Bo Su, Junhu Meng, Aijun Zhang, Youzhi Wu

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: refractory high-entropy alloys; fused slurry method; silicide coating; Si-20Cr-20Fe; high-temperature oxidation

Online: 7 July 2020 (09:43:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0106.v1

Meta-Analysis of Fiber Impact on Mechanical Properties of Ultra-High Performance Concrete

Faiq M. Al-Zwainy

Subject: Engineering, Civil Engineering Keywords: Meta-analysis; Effect size; Precision; Ultra-high strength concrete; Ultra-high strength fiber reinforced concrete

Online: 7 April 2020 (13:28:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0322.v1

Comparative Analysis of Compiler Performances and Program Efficiency

Paul Tawo Bukie, Chinedu Leonard Udeze, Iwara Ofem Obono, Edim Bassey Edim

Subject: Computer Science And Mathematics, Computer Science Keywords: java virtual machine (jvm); high level programming languages; high performance computing (hpc); php framework; compiler

Online: 29 September 2019 (05:01:46 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0361.v1

On Burden of Diseases, Prevention, Medical Research and Health Service Delivery: Grampian Case Study

Seshadri Vasan, Nicholas Fluck

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: burden of disease; disability-adjusted life year (DALY); disease prevention; epidemiology; health policy; health service; health surveillance; medical research; public health

Online: 6 December 2023 (08:07:09 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202106.0486.v1

The Oxygen Transport Triad in High Altitude Pulmonary Edema: a Perspective from the High Andes

Gustavo Zubieta-Calleja, Natalia Zubieta-DeUrioste

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: high altitude, chronic hypobaric hypoxia, physiologic adaptation, travel to high altitude cities, high altitude physiology, pulmonary hypertension, lung disease, hemoglobin, tolerance to hypoxia, oxygen content.

Online: 18 June 2021 (15:22:04 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202402.1610.v1

Exceptional Lithography Sensitivity Boosted by Hexafluoroisopropanols in Photoresists

Junjun Liu, Dong Wang, Yitan Li, Haihua Wang, Huan Chen, Qianqian Wang, Wenbing Kang

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Hexafluoroisopropanol; high-sensitivity; photoresist; photoacid generation

Online: 28 February 2024 (08:04:18 CET)

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Preprint REVIEW | doi:10.20944/preprints202307.1092.v1

Survey on Fungi in Antarctica and High Arctic Regions, and Their Impact on Climate Change

Masaharu Tsuji

Subject: Environmental And Earth Sciences, Ecology Keywords: Antarctica; High Arctic; fungi; climate change

Online: 17 July 2023 (09:48:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202211.0353.v1

The Relationship between Association between Blood Pressure and Risk of Cancer Development

Nikolaos Tzenios, Mary Tazanios, Mohamad Chahine

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: high blood pressure; Cancer; malignancies; hypertension

Online: 18 November 2022 (10:05:11 CET)

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Background of the Study: We investigated the link between hypertension and cancer since it has been suggested that hypertension may raise the long-term risk of cancer. Previous large observational cohort studies found that greater blood pressure (BP) was related to a higher risk of cancer. Mendelian randomization (MR) was utilized to produce less confounded blood pressure estimates (BP) on overall and site-specific malignancies. The study aims to draw conclusions on the relationship between high blood pressure and cancer. Methods: Studies on high blood pressure and various malignancies are inconclusive, except for renal cell carcinoma. However, given that most meta-analyses only contained a limited number of trials, some relative risks had small to moderate magnitudes, and several may have been impacted by residual confounding, careful interpretation is necessary. The study was conducted using the meta-analysis technique. Cochran's Q test and I2 test were used to assess statistical heterogeneity between studies in the current investigation for research involving two or more cause and outcome combinations. Results: Positive correlations were also reported between high blood pressure and esophageal adenocarcinoma, squamous cell carcinoma, liver, and squamous cell carcinoma. However, most studies lacked multivariable adjustments. Physical and numerical risk of cardiovascular disease is linked to bowel cancer but no other cancers. According to a meta-analysis, hypertensive persons could also be at increased danger of gastrointestinal and breast cancer. Most meta-analyses comprised several trials with moderate or mild hazard ratios.ConclusionDifferent types of cancers have been noted to be directly caused by hypertension. In addition, some treatments have also been associated with the side effects of cancer treatments to cause hypertension. Women facing hypertension have an increased risk of getting breast cancer. Although some cancers showed a real relationship with hypertension, others had no connection at all.

Preprint ARTICLE | doi:10.20944/preprints202104.0598.v1

Influence of Chromium Concentration on the Abrasive Wear Of Ni-Cr-B-Si Coatings Applied by High-Velocity Oxygen Fuel

Zhetcho Doinov Kalitchin, Mara Krumova Kandeva, Yana Petrova Stoyanova

Subject: Chemistry And Materials Science, Biomaterials Keywords: high-velocity oxygen fuel; chromium; abrasion

Online: 22 April 2021 (09:24:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0493.v1

Integral Order Photonic RF Signal Processors Based on Kerr Micro-combs

Mengxi Tan, Xingyuan Xu, David Moss

Subject: Engineering, Automotive Engineering Keywords: microcombs; filters; high bandwidth; RF photonics

Online: 19 April 2021 (13:51:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0178.v1

Dyad Model as a Caring Innovation in High Risk Pregnancy

Sri Wahyuni, Moses Glorino Rumambo Pandin

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Dyad Model; Caring; High Risk Pregnancy

Online: 6 April 2021 (13:30:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0162.v1

Tunable Broadband RF Photonic Fractional Hilbert Transformer Based on a Soliton Crystal Microcomb

Mengxi Tan, Xingyuan Xu, David Moss

Subject: Engineering, Automotive Engineering Keywords: microcombs; filters; high bandwidth; RF photonics

Online: 6 April 2021 (10:06:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0069.v3

Investigation of Constraints to be Occured in Participation to the Leisure Activities of High School Students: Sample of Turkey

Cihan Ayhan, Nurullah Emir Ekinci, Ilimdar Yalcin, Sihmehmet Yigit

Subject: Social Sciences, Behavior Sciences Keywords: high school; student; leisure; leisure constraints

Online: 18 May 2018 (05:54:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0062.v1

Prognostic Significance of High Survivin Expression in Patients with Gastrointestinal Cancer: A Meta-Analysis

Pingping Xu, Jiajia Lin, Qi Lin, Dexiang Zhu, Wentao Tang, Zhengchuan Niu, Mi Jian, Yanru Wang, Chunmin Liang, Jianmin Xu

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: survivin; high expression; gastrointestinal cancer; prognostic

Online: 11 April 2017 (10:51:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202312.1070.v1

Highlights of the Magic Florian Goebel Telescopes in the Study of Active Galactic Nuclei

Marina Manganaro, Dijana Dominis Prester

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: γ -ray astrophysics; Active galactic nuclei; very-high-energy gamma rays; non-thermal; high energy astrophysics

Online: 14 December 2023 (08:32:44 CET)

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Preprint REVIEW | doi:10.20944/preprints202008.0496.v1

A Review for Southern Highbush Blueberry Alternative Production Systems

Yang Fang, Gerardo H. Nunez, Mariana Neves da Silva, Douglas A. Phillips, Patricio R. Munoz

Subject: Biology And Life Sciences, Horticulture Keywords: Vaccinium corymbosum interspecific hybrids; high tunnel; greenhouse; plant factory; non-dormant; substrate; container; evergreen; high density

Online: 24 August 2020 (02:56:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0050.v1

Preparation and Evaluation of an Elusive Polymorph of Mefenamic Acid by High Pressure Techniques

Nasir Abbas, Iain Oswald, Colin R. Pulham

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: mefenamic acid; diamond anvil cell; high-pressure; polymorphism; high-pressure crystallization; non-steroidal anti-inflammatory drugs

Online: 8 March 2017 (08:58:38 CET)

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Preprint REVIEW | doi:10.20944/preprints202105.0549.v1

What Could Explain the Lower COVID-19 Burden in Africa Despite Considerable Circulation of the SARS-CoV-2 Virus?

Richard G. Wamai, Jason L. Hirsch, Wim Van Damme, David Alnwick, Robert C. Bailey, Stephen Hodgins, Uzma Alam, Mamka Anyona

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19 pandemic; Africa; SARS-CoV-2 virus spread; lower COVID-19 disease burden; African populations; demographic pyramid; trained immunity; government measures

Online: 24 May 2021 (09:56:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0189.v1

The Global Burden of Type 2 Diabetes Attributable to Dietary Risks: Insights from the Global Burden of Disease Study 2019

Alina Ioana Forray, Mădălina Adina Coman, Ruxandra Simonescu-Colan, Andreea Isabela Mazga, Răzvan Mircea Cherecheș, Cristina Maria Borzan

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: type 2 diabetes mellitus; Global Burden of Disease Study; dietary risk factors; Age- Standardized Mortality Rate; Age-Standardized DALY Rate; Socio-Demographic Index

Online: 4 October 2023 (04:55:59 CEST)

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Preprint INTERESTING IMAGES | doi:10.20944/preprints202301.0439.v1

Low Health Literacy (LHL): A Devious Enemy of Patient Treatment Adherence

Abdul Kader Mohiuddin

Subject: Social Sciences, Psychology Keywords: parental health literacy; necessary health education; understanding treatment guidelines; medication non-adherence; healthcare; avoidable medical costs; global health burden; COVID-19 vaccine negligence

Online: 25 January 2023 (03:43:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0237.v2

Toward Evaluation of The Subjective Experience of A General Class of User-Controlled, Robot-Mediated Rehabilitation Technologies for Children with Neuromotor Disability

Manon Maitland Schladen, Kevin Cleary, Yiannis Koumpouros, Reza Monfaredi, Tyler Salvador, Hadi Fooladi Talari, Jacob Slagle, Catherine Coley, Staci Kovelman, Justine Belschner, Sarah Helen Evans

Subject: Social Sciences, Behavior Sciences Keywords: Game-based therapy; robot-mediated therapy; neuromotor disability; cerebral palsy; subjective assessment; patient-centered assessment; caregiver burden; ankle range of motion; ankle strengthening; home exercise program

Online: 12 October 2020 (10:09:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0296.v1

Wenzhou TE: A First-Principles Calculated Thermoelectric Materials Database

Ying Fang, Hezhu Shao

Subject: Physical Sciences, Condensed Matter Physics Keywords: Thermoelectric Materials; Material Databases; High-throughput Computing

Online: 3 April 2024 (12:25:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1298.v1

Analysis of Attitudes and Practices towards the Influenza Vaccine in High-Risk Adults in Poland

Dorota Kopciuch, Karolina Hoffmann, Krzysztof Kus, Agnieszka Koligat-Seitz, Piotr Ratajczak, Elżbieta Nowakowska, Anna Paczkowska

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: vaccines; influenza; high-risk groups; attitudes; practice

Online: 23 February 2024 (08:30:56 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.0905.v1

Research Status and Development Trend of High-Pressure Water Jet Nozzle

Hongjie Niu, Yuntao Hou, Yafei Lei, Dongyang Li, Yi Yang, Guoyu Song

Subject: Engineering, Mechanical Engineering Keywords: High pressure water jet; Nozzle; Research status

Online: 11 January 2024 (11:00:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0163.v1

A Novel Orthogonally High Isolation CPW Fed UWB MIMO Antenna for IoT Applications

Muhammad Zahid, Nirman Bhowmike, Zaeem Mazhar, Asma Ejaz, Sultan Shoaib, Yasar Amin

Subject: Engineering, Electrical And Electronic Engineering Keywords: UWB; MIMO; Internet of thing; high isolation

Online: 4 December 2023 (07:51:16 CET)

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