Epsilon-near-zero nanoantennas can be used to tune the far-field radiation pattern due to their exceptionally large intensity-dependent refractive index. Here, we propose hybrid optical antenna based on indium tin oxide (ITO) to optically tune the deflection of radiation. In particular, a hybrid structure antenna of ITO and dielectric material, which makes the deflection angle changes 17 ∘ as incident intensities increases. Finally, the array of ITO or hybrid nanodisks can enhance the unidirectionality to be needle-like, with the angular beam width α< 8∘ of main lobe. The deflection angle of radiation pattern response with needle-like lobe pave the way for further studies and applications in beam steering and optical modulation where dynamic control of the nanoantennas is highly desirable.

The spectral properties of a one-dimensional photonic crystal bounded by a resonant absorbing nanocomposite layer with the near-zero permittivity have been studied. The problem of calculating the transmittance, reflectance, and absorptance spectra of such structures at the normal and oblique incidence of light has been solved. It is shown that, depending on the permittivity sign near zero, the nanocomposite is characterized by either metallic or dielectric properties. For the first time, the possibility of simultaneous formation of the Tamm plasmon polariton at the photonic crystal/metallic nanocomposite interface and the localized state similar to the defect mode with the field intensity maximum inside the dielectric nanocomposite layer is demonstrated. Specific features of field localization at the Tamm plasmon polariton and defect mode frequencies are analyzed.

New advances of nano-enabled weed management: using poly(epsilon-caprolactone)-based nanoherbicides. A review

As Cybercrimes continue to rise, researchers and industry players have continued to work hard to come up with solutions that could reduce and possibly eradicate these criminalities. This research has been able to discover the major factor that usually causes people to fall prey to these cyber criminals. This was why a school of thought came up with the Zero Trust Access model to strengthen the network framework. While previous network assets relied on the "trust but verify" philosophy, this technology's primary tenet is "never trust, always verify," which applies to every user and device connected to the network. This study interrogated the existing network models of the Integrative Trust Model (ITM) and Zero Trust Access (ZTA) in addition to the trust model (TA) to understand their concepts, implementation needs, strengths, and shortcomings. This made it possible for the study to establish the position of the ZTA model in repositioning the network security architectures vis-a-vis protecting the users

In recent years, the management of health systems is a main concern of governments and decision makers. Home health care is one of the newest methods of providing services to patients in developed societies that can respond to the individual lifestyle of modern age and the increase of life expectancy. The home health care routing and scheduling problem is a generalized version of the vehicle routing problem, which is extended to a complex problem by adding special features and constraints of health care problems. In this problem, there are multiple stakeholders such as nurses for which an increase of their satisfaction level is very important. In this study, a mathematical model is developed to expand traditional home health care routing and scheduling models to downgrading cost aspects by adding the objective of minimizing the difference between the actual and potential skills of the nurses. Downgrading can lead to a dissatisfaction of the nurses. In addition, skillful nurses have higher salaries and high-level services increase equipment costs and need more expensive trainings and nursing certificates. Therefore, downgrading can enforce hidden huge costs to the managers of a company. To solve the bi-objective model, an -constraint based approach is suggested and the model applicability and its ability to solve the problem in various sizes are discussed. A sensitivity analysis on the Epsilon parameter is conducted to analyze the effect of this parameter on the problem. Finally, some managerial insights are presented to help the managers in this field, and some directions for future studies are mentioned as well.

While the knowledge about the development of understanding positive integers is rapidly growing, the development of understanding zero is not well-known. Here we tested several components of preschoolers’ understanding zero: whether they can use empty sets in numerical tasks, whether they can use empty sets soon after they understand the cardinality principle, whether they know what the word “zero” refers to, and whether they categorize zero as a number. The results show that preschoolers can handle empty sets in numerical tasks as soon as they understand the cardinality principle or even earlier, and some of them know that these sets are labeled as “zero.” However, they are unsure whether zero is a number. These results identify three components of knowledge about zero: operational knowledge, linguistic knowledge, and meta knowledge. To account for these results we propose that preschoolers might understand numbers as the properties of items or objects in a set. In this view, zero cannot be a number, because an empty set does not include any items, and the missing items cannot have any property, excluding also the number property. This model might explain why zero is handled correctly in numerical tasks, while it is not regarded to be a number.

Zero-shot learning ability robotics enables robots to generalize their knowledge and perform tasks for which they have not been explicitly trained. This ability is extremely helpful because in classic learning approaches, robots are trained on specific tasks and require extensive data and labeled examples to perform accurately. However, in real-world scenarios, robots often encounter new or unseen tasks that were not part of their training data. We briefly survey works in this area to give the reader a perspective about progresses in this area.

While there is a coordinated effort around reaching zero dose children and closing existing equity gaps in immunization delivery, it’s important that there is agreement and clarity around how ‘zero dose status’ is defined and what is gained and lost by using different indicators for zero dose status. There are two popular approaches used in research, program design, and advocacy to define zero dose status: one uses a single vaccine to serve as a proxy for zero dose status, while another uses a subset of vaccines to identify children who have missed all routine vaccines. We provide a global analysis utilizing the most recent publicly available DHS and MICS data to compare the number, proportion, and profile of children 12 to 23 months who are ‘penta-zero dose’ (have not received the pentavalent vaccine), ‘truly’ zero dose (have not received the BCG, polio, pentavalent, and measles vaccines), and ‘misclassified’ zero dose children (those who are penta-zero dose but have received at least one other vaccine). Our analysis includes 194,829 observations from 82 low- and middle-income countries. Globally, 14.2% of children are penta-zero dose and 7.5% are truly zero dose, suggesting that 46.5% of penta-zero dose children have had at least one contact with the immunization system. While there are similarities in the profile of children that are penta-zero dose and truly zero dose, there are key differences between the proportion of key characteristics among truly zero dose and misclassified zero dose children, including access to maternal and child health services. By understanding the extent of connection zero dose children may have with the health and immunization system and contrasting it with how much the use of a more feasible definition of zero dose may underestimate the level of vulnerability in the zero dose population, we provide insights that can help immunization programs design strategies that better target the most disadvantaged populations. If the vulnerability profiles of the truly zero dose children are qualitatively different from that of the penta zero dose children, then failing to distinguish the truly zero dose populations, and how to optimally reach them, may lead to the development of misguided or inefficient strategies for vaccinating the most disadvantaged population of children.

We document for the first time epsilon waves on the electrocardiogram of a patient with Dravet syndrome (DS) who does not exhibit structural cardiac pathology. DS, a severe form of pediatric epilepsy, involves mutations in the SCN1A gene, which disrupt sodium ion flow and increase the risk of sudden unexpected death in epilepsy. The epsilon waves, typically associated with arrhythmogenic right ventricular dysplasia, may also suggest a link between neuronal and cardiac dysfunctions. In our case, the epsilon waves appear to originate from abnormalities in sodium channels rather than structural changes in the myocardium. This finding underscores the importance of assessing both neurological and cardiac manifestations in patients with severe epilepsy, opening new avenues for the research and treatment of these interactions in DS.

The zero-catch problem is a key issue in CPUE(Catch Per Unit Effort) standardization, and previous studies have treated all zero-catch data uniformly, but this actually loses some correctly-labeled samples. On the other hand, for the main catches with few zero-catch samples, the problem of low performance of fisheries forecasting remains unsolved even though the forecasting model structure is updating constantly, since we cannot know whether the samples are correctly recorded. In this paper, we propose a method based on confident learning theory to detect anomalous samples in the datasets and unify zero-catch and non-zero samples as noise through an overarching framework of learning with noisy labels, which reveals the heterogeneity among zero-catch samples (as well as among non-zero samples) and the homogeneity between zero-catch samples and non-zero samples. Using three species of tuna in the tropical Atlantic Ocean with the spatial resolution of 0.5 ◦ × 0.5 ◦ and time resolution of days from 2016 to 2019 as experimental material, performance on all three classical machine learning models(Random forest, Support Vector Machine and XGBoost) is significantly improved compared to each baseline.This confirms that we propose a self-adaptive, effective method for detecting and repairing anomalous samples in the fishery dataset.

Introduction The monitoring of cerebral perfusion in patients with brain damage is a major clinical challenge. Monitoring cerebral oxygenation (rSO2) by NIRS was introduced at the turn of the 1980s, and many clinicians believed it was a valuable method for assessing cerebral perfusion and subsequent measures to optimize cerebral flow. The main problem of NIRS usage is the presence of the intermediate structures-skin, skull, meninges, cerebrospinal fluid-and their influence on the outcome of the test. Therefore, it seems that NIRS assessment performed on a patient during brain death attempts, can give an idea of the magnitude of the influence of these intermediate structures on the monitoring result. Case We present a retrospective analysis of cerebral oxygenation measurements of a patient undergoing a brain death diagnostic procedure. A clinical situation where the cerebral blood flow is stopped can give an idea of the specificity of the method, particularly the impact of the influence of intermediate structures on the monitoring outcome. In this case, the NIRS result is increased by the oxygenation of the patient before the apnoea test. The influence of chromophores in the tissues surrounding the CNS, reflections and scattering of the light wave spectrum have a very significant effect on the final result of cerebral saturation measurement. Discussion The majority of research observations describing changes in cerebral perfusion or its optimisation may be burdened by the problem described, i.e. the significant influence of measured oxygenation from intermediate structures. The specificity of NIRS to assess cerebral perfusion requires careful analysis. The therapeutic implications of monitoring cerebral oxygenation with NIRS are of great importance and, from the example presented and the literature provided, the method should be used with caution. It has been shown that in a patient with brain death, the result of NIRS oxygenation measurements depends on the surrounding structures of the brain.

porous silicon-based photodetectors have attracted more researches due to their high luminous efficiency, good stability and low cost. In this paper, a PbS quantum dots/porous silicon hybrid structure has been fabricated. The PbS quantum dots (QDs) partly infiltrated into the porous silicon (PSi) layer and partly deposited on its surface, which could increase the absorption of near-infrared wavelength range and extend the light absorption in silicon for wavelengths longer than 1100 nm. After that, A metal-semiconductor-metal (MSM) device is fabricated and its response spectrum could extend to the 1200 nm at -3 V. As a silicon-based photodetector (PD), one can envision its role for operation from visible light to short-wavelength infrared range.

The study presents an assessment of climate suitability for outdoor leisure activities in Romania using the Holliday Climate Index (HCI) for the near future (2021-2040), focusing on unfavorable and good climate conditions. The analysis employs data from an ensemble model in the context of RCP45 and RCP85 climate change scenarios. The results indicate that the number of days with low weather suitability is decreasing in almost the entire country, especially during the warm season, while during the winter and spring extended regions may be characterized by a higher number of days favorable for outdoor activities than during the current climate. An estimation of the impact of climate changes on tourism flux in Romania is further carried out, suggesting that the increasing attractivity of climate conditions may lead to an increased number of tourist overnights in the near future, more pronounced in rural destinations.

In European Seveso Legislation for the control of the hazard of major accidents (Directive 2015/12/UE), the Safety Management System SMS is an essential obligation for managers and the authorities are required to periodically verify its adequateness through periodical inspections at Seveso sites. One of the pillars of the SMS is the collection and analysis of documents on accidents, near misses and possibly anomalies, in order to identify weaknesses and implement continuous improvement. In Italy, for a few years, the documents, gathered from all Italian Seveso sites by the inspectors, have been archived and used for research purposes. The archive currently contains some 4000 reports, collected in five years by some 100 inspectors throughout Italy. The paper discusses in the detail the challenges faced to extract the knowledge hidden in the documents and make it usable through the design of a robust model. For this aim, Machine Learning techniques have been used as a preprocessing of the reports for extracting the concepts and their relations, organized into an entity-relation model. The effectiveness of this methodology and its potentiality are pointed out by investigating a few hot topics, exploiting the information contained in the repository.

Zero-dose children, or children who have not received any routine vaccination, are a priority population for global health policy makers as these children are at high risk of mortality from vaccine-preventable illnesses. We conducted a narrative review to identify potential interventions, both within and outside of the health sector, to reach zero-dose children. We reviewed peer-reviewed and grey literature and identified 59 relevant resources. Additionally, we interviewed six key informants to enhance synthesis of our findings. Data were organized into three priority settings: (1) urban slums, (2) remote or rural communities, and (3) conflict settings. We found that zero-dose children in the three-priority settings face differing barriers to vaccina-tion and, therefore, require context-specific interventions, such as leveraging slum health commit-tees for urban slums or integrating with existing humanitarian response services for conflict set-tings. Three predominant themes emerged for grouping the various interventions: (1) community engagement, (2) health systems strengthening and integration, and (3) technological innovations. The barriers to reaching zero-dose children are multifaceted and nuanced to each setting, there-fore, no one intervention is enough. Technological interventions especially must be coupled with community engagement and health systems strengthening efforts. Evaluations of the suggested interventions are needed to guide scale up, as the evidence-base around these interventions is rel-atively small.

The Global Burden of Disease Study (GBD 2019 Diseases and Injuries Collaborators) found that diabetes significantly increases the overall burden of disease, leading to a 24.4% increase in disability-adjusted life years. Persistently high glucose levels in diabetes can cause structural and functional changes in proteins throughout the body, and the accumulation of protein aggregates in the brain is associated with the progression of Alzheimer's Disease (AD).To address this burden of type 2 diabetes mellitus (T2DM), a combined aerobic and resistance exercise program was developed based on the recommendations of the American College of Sports Medicine. The prospectively registered clinical trials (https://www.clinicaltrials.gov/ct2/show/NCT04626453, https://www.clinicaltrials.gov/ct2/show/NCT04812288) involved two groups: an Intervention group of older sedentary adults with T2DM and a Control group of healthy older adults who could be either active or sedentary. The completion rate for the 2-month exercise program was high, with participants completing on an average of 89.14% of the exercise sessions. This indicated that the program was practical, feasible, and well-tolerated, even during the COVID pandemic. It was also safe, requiring minimal equipment and no supervision. The exercise instructions were easy to understand, making them suitable for older adults with cognitive decline.The near-infrared spectroscopy (NIRS) based brain and muscle oxygenation study provided evidence on brain overactivation among older adults with T2DM, supporting the compensatory theory. It also demonstrated that the 2-month combined exercise intervention effectively reduced brain overactivation and contributed to improved cognitive function. Operational modal analysis showed an exercise-related effect on the very low-frequency hemodynamic oscillations cluster, which may be associated with better vascular muscle and/or perivascular neurogenic regulation. Furthermore, we personalized the exercise duration and interval based on muscle oxygenation during physical tasks, leading to improvements in muscle oxidative capacity within just two months. This finding has practical implications for physical therapists, as they can target muscle oxygenation changes during physical tests to prescribe appropriate exercise doses for enhancing physical performance.

In this work, we present preliminary results of radar observations of near-Earth Objects (NEOs) carried out by European radio telescopes in the framework of the European Space Agency (ESA) project “NEO observation concepts for radar systems”, which was aimed to derive the functional requirements of a radar system, evaluate the available European assets to perform NEO radar observations and carry out test radar campaigns. In the first part of the project, we carried out the performance analysis of a possible European planetary radar system. Instrumental features, as much as issues like the impact of weather conditions on signal propagation at different radio frequencies, were considered. This paper is focused on the test campaigns, performed in the years 2021-22 in collaboration with the Jet Propulsion Laboratory (JPL), which led to the observation of several asteroids including 2021 AF8, (4660) Nereus and 2005 LW3, which allowed us to derive astrometric measurements, as well as to measure physical properties, such as rotation periods, and detect an asteroid’s satellite. The obtained results demonstrate that European radio astronomical dishes, although employed only as receivers (in bistatic or multistatic configurations) and for a limited amount of time, are able to provide a significant contribution to the constitution of a European network to increase the opportunities for NEO monitoring and studies, if a transmitting antenna - equipped with a suitable high-power transmitter - were made available.

Near Inertial Oscillations (NIOs) are ocean oscillations forced by intermittent winds. They are most energetic at mid-latitudes, particularly in regions of atmospheric storm tracks. Wind-driven, large-scale NIOs are quickly scattered by ocean mesoscale eddies (with sizes ranging from 100 to 400 km), causing a significant portion of the NIO energy to propagate into the ocean interior. This kinetic energy pathway illustrates that the wind energy input to NIO, estimated at 5 TeraWatts, is critical for maintaining deep ocean stratification and thus closing the total kinetic energy budget, as emphasized by numerous modelling studies. However, this wind energy input to NIO remains poorly observed on a global scale. A remote sensing approach, which observes winds and ocean currents co-located in time and space with high resolution, is necessary to capture the intermittent air-sea coupling. The current satellite observations do not meet these requirements. This study assesses the potential of a new satellite mission concept, Ocean DYnamics and Surface Exchange with the Atmosphere (ODYSEA), to recover wind-forced NIOs from co-located winds and currents. To do this, we use an Observation System Simulation Experiment (OSSE) based on hourly observations of ocean surface currents and surface winds from five surface moorings covering latitudes from 15∘ to 50∘. ODYSEA wind and current observations are expected to have a spatial resolution of 10 km with about 12-hour sampling frequency in mid-latitudes. Results show that NIOs can be recovered with high accuracy using the ODYSEA spatial and temporal resolution, only if observations are made in a wide-swath of 1,800 km. A narrower swath (1,000 km) may lead to significant aliasing.

The initial dilution generated by the final disposal of untreated wastewater through a submarine outfall in Santa Marta was examined with a near-field dilution model. Northward and eastward seawater velocity, salinity, and temperature profiles from a 3D hydrodynamic model were used to provide the oceanic conditions to calculate the dilution. At the wastewater discharge site, the upwelling phenomenon occurs two times a year, the major from December to March and the minor in July, eliminating the stratification condition of seawater. The results of the dilution model showed that in these periods the plume reaches the water surface achieving dilutions greater than 100. In addition, the external wave effect on the initial dilution of submarine outfall discharge in Santa Marta was determined. Surface waves increase dilution during the dry period of the year when trade winds increase the surge and start the upwelling phenomenon. The Dilution with/without waves factor is up to 1.90 for the center of the plume on the water column.

This paper presents the design, fabrication and characterization of Schottky erbium/silicon photodetectors working at 1.55 µm. These erbium/silicon junctions are carefully characterized using both electric and optical measurements at room temperature. A Schottky barrier ΦB of ~673 meV is extrapolated; the photodetectors show external responsivity of 0.55 mA/W at room temperature under a 8 V of reverse bias applied. In addition, the device performance is discussed in terms of normalized noise and noise equivalent power. To the best of our knowledge, these are the first Er/Si photodetectors designed for operation in free space at 1.55 µm. The proposed devices will pave the way towards development of Er-based photodetectors and light sources to be monolithically integrated in the same silicon substrate and both operating at 1.55 µm.

Energy market price volatility and an upward trajectory of prices per unit of electricity have sent all industrial sectors and many economies to the brink of recession. Alongside the urgent need for decarbonisation of all industries, achieving a higher level of energy independence across all sectors seems imperative. A multi-disciplinary approach with a proposed system of CO₂ emissions reduction and capture technologies has the potential for short-term emissions reduction to near-zero in absolute terms. The findings of this research showed CO₂ emissions reduction of ~30% from 977t of CO_2e to 684t in one single blast furnace production cycle, by switching the energy provider generating energy exclusively from renewable sources. Replacing coal with biomass (BECCS), resulted in an additional reduction of ~30%, to CO_2e to 479t CO_2e. Installing solar PV panels for energy generation on site resulted in a further ~30% reduction, to 335 tonnes CO_2e. Finally, the installation of CO₂ filters reduced the CO₂ emissions to near-zero. Simultaneously, energy-saving and process improvement measures implementation (up to 60% efficiency increase), excess heat recovery (<30% of energy savings), and retrofitting renewable energy technology resulted in an energy independence of 88%. Short-term engineering solutions, partly subsidised in the UK, are readily available.

Recently, the focus of entity linking research has centered on the zero-shot scenario, where the entity mention to be labeled at the time of testing was never observed during the training phase or may belong to a different domain than the source domain. Current studies have used BERT as the base encoder as it effectively establishes distributional links between source and target domains. The currently available negative sampling methods all use an extractive approach, which makes it difficult for the models to learn diverse and more challenging negative samples. To address this problem, we propose a generative negative sampling method, Adaptive_mixup_hard, which generates more difficult negative entities by fusing the features of both positive and negative samples on top of hard negative sampling and introduces a transformable adaptive parameter W to increase the diversity of negative samples. Next, we fuse our method with the Biencoder architecture and evaluate its performance under three different score functions. Ultimately, experimental results on the standard benchmark dataset Zeshel demonstrate the effectiveness of our method.

The global agricultural sector is increasingly pressured to adopt sustainable practices and reduce its environmental impact. In this context, greenhouses play a crucial role in enabling year-round crop production, ensuring food security, and minimizing reliance on traditional open-field farming. However, the energy consumption associated with greenhouse operations poses a significant challenge to achieving sustainability goals. As a result, there is a growing emphasis on transitioning greenhouses towards near-zero energy consumption. Near-zero energy consumption in greenhouses refers to the ambitious objective of minimizing energy usage to the greatest extent possible while maintaining optimal growing conditions for crops. This goal encompasses reducing energy consumption for heating, cooling, lighting, and other operational needs, as well as exploring renewable energy sources to power greenhouse operations. This review article offers a comprehensive overview of greenhouse energy consumption, with the main goal of analyzing the present situation, identifying key challenges, exploring potential opportunities, and proposing future perspectives for decreasing energy usage in greenhouse environments. As the focus on sustainable agricultural practices grows, the need to reduce energy consumption in greenhouses becomes increasingly important. The review critically examines current technological models and strategies applied in smart greenhouse applications, as well as the monitoring of microclimatic conditions inside the greenhouse, encompassing factors such as temperature, humidity, CO2 levels, soil quality, and crop cultivation. Moreover, it aims to present existing literature that investigates the advancement of greenhouses toward achieving significant reductions in energy consumption.

Through history, particular attention has been paid of the study of the relationship between the energy use and the city structure. Improving energy efficiency in modern agglomerations is the most promising means to mitigate climate change and its impacts. In this current context of globalisation, European Union proposes initiatives and policy targets to rethink the urban development strategies towards the ‘zero energy objectives’. Providing a methodological approach with a simulation district analysis, the present article summarizes how the ‘zero energy’ challenge is analyzed in an existing district (Epinlieu) to articulate the users’ requirements in energy. This study contributes to the scientific discussion of the districts’ urban structure and energy planning by establishing a linkage among the beneficial influence of the KPIs of the districts’ form to increase their energy efficiency and its application in a real case study in Belgium.

Leveraging the open-world understanding capacity of large-scale visual-language pre-trained models has become a hot-spot in point cloud classification. Recent approaches rely on transferable visual-language pre-trained models, classifying point clouds by projecting them into 2D images and evaluating consistency with textual prompts. These methods benefit from the robust open-world understanding capabilities of visual-language pre-trained models and require no additional training. However, they face several challenges summarized as prompt ambiguity, image domain gap, view weights confusion, and feature deviation. In response to these challenges, we propose PointBLIP, a zero-training point cloud classification network based on the recently introduced BLIP-2 visual-language model. PointBLIP is adept at processing similarities between multi-images and multi-prompts. We separately introduce a novel method for point cloud zero-shot and few-shot classification, which involves comparing multiple features to achieve effective classification. Simultaneously, we enhance the input data quality for both the image and text sides of PointBLIP. In point cloud zero-shot classification tasks, we outperform state-of-the-art methods on three benchmark datasets. For few-shot classification tasks, to the best of our knowledge, we present the first zero-training few-shot point cloud method, surpassing previous works under the same conditions and showcasing comparable performance to full-training methods.

Background: Visual acuity (VA) assessments are crucial in ophthalmology but traditionally rely on in-clinic evaluations. The emergence of telemedicine has spurred interest in creating dependable self-administered VA tests for use beyond standard clinical environments. This study evaluates the practicality and validity of a self-administered Near VA card test against traditional Snellen and Rosenbaum Pocket Vision Screener (RPVS) methods for home monitoring and enhancing clinical workflow. Methods: In a cross-sectional study a near VA card (Hadassah Self-Visual Acuity Screener-HSVA) was developed with written and videotaped instructions for self-use. Patients with a minimal best corrected VA (BCVA) of 1.0 LogMAR in at least one eye were recruited from Ophthalmology and Optometry clinics. Outcomes included mean BCVA difference between the self-administered and those obtained by the examiner, and correlations among BCVA values obtained by Snellen, RPVS, HSVA and previous distance BCVA according to the patient electronic medical records. Results: A total of 275 participants (mean age: 42.5±19.4 years, range: 18-89 years, 47% female) were included. Test-retest reliability analysis for the HSVA demonstrated very good correlation and repeatability (n=38 patients.; Rs=1.0, P

The study aimed to evaluate the association between the changes in ventilatory variables (tidal volume (Vt), respiratory rate (RR), and lung ventilation (VE)) and deoxygenation of m.intescostales (∆SmO2-m.intercostales) during a maximal incremental exercise in nineteen male competitive marathon runners. The ventilatory variables and oxygen-consumption (VO2) were recorded breath-by-breath by exhaled gas analysis. A near-infrared spectroscopy device (MOXY) located in the right-hemithorax allowed recording SmO2-m.intercostales. To explore changes in oxygen levels in muscles with high demand during exercise, a second MOXY records SmO2-m.vastus laterallis. The triphasic model of exercise intensity was used for evaluating changes in SmO2 in both muscle groups. We found that ∆SmO2-m.intercostales correlated with VO2-peak (r=0.65; p=0.002) and the increase of VE (r=0.78; p=0.001), RR (r=0.54; p=0.001), but not Vt (p=0.210). The interaction of factors (muscles X exercise-phases) in SmO2 expressed as an arbitrary unit (a.u) was significant (p=0.005). At VT1 were no difference (p=0.177), but SmO2-m.intercostales was higher at VT1 (p<0.001) and VO2-peak (p<0.001). In competitive marathon runners, the m.intercostales deoxygenation during incremental exercise is directly associated with the aerobic capacity and increased lung ventilation and respiratory rate, but not tidal volume. Besides, it shows less deoxygenation than m.vastus laterallis at intensities above the aerobic ventilatory threshold.

In this work we theoretically investigate the responsivity/noise equivalent power (NEP) trade-off in graphene/semiconductor Schottky photodetectors (PDs) operating in the near-infrared regime and working at room temperature. Our analysis shows as the responsivity/NEP ratio is strongly dependent on the Schottky barrier height (SBH) of the junction and we derive a closed analytical formula for maximizing it. In addition, we theoretically discuss as the SBH is linked to the bias applied to the junction in order to show how these devices could be optimized in practice for different semiconductors. We discover that graphene/n-silicon (Si) Schottky PDs could be optimized at 1550nm showing a responsivity and NEP of 133mA/W and 500fW/Hz, respectively, by a low reverse bias of only 0.66V. Moreover, we show that graphene/n-germanium (Ge) Schottky PDs optimized in term of responsivity/NEP ratio could be employed at 2000nm with a responsivity and NEP of 233mA/W and 31pW/Hz, respectively. We believe that our insights are of great importance in the field of silicon photonics for the realization of Si-based PDs to be employed in power monitoring, lab-on-chip and environment monitoring applications.

Heavy metals pollution in the Straits of Malacca warrants the development of rapid, simple and sensitive assays. Enzyme-based assays are excellent preliminary screening tool with near real-time potential. The heavy-metal assay based on the protease ficin was optimized for mercury detection using Response Surface Methodology. The inhibitive assay is based on ficin action on the substrate casein and residual casein is determined using the Coomassie dye-binding assay. Heavy metals strongly inhibit the hydrolysis. A Central Composite Design (CCD) was utilized to optimize detection. The results show a marked improvement for the concentration causing 50% inhibition (IC50) for mercury, silver and copper. Compared to One-factor-at-a-time (OFAT) optimization, RSM gave an improvement of IC50 from 0.060 (95% CI, 0.0300.080) to 0.017 (95% CI, 0.0160.019), from 0.098 (95% CI, 0.0770.127) to 0.028 (95% CI, 0.0220.037) and from 0.040 (95% CI, 0.035.045) to 0.023 (95% CI, 0.0200.027), for mercury, silver and copper, respectively. A near real-time monitoring of mercury concentration in the Straits of Malacca at one location in Port Klang was carried out over a 4-h interval for a total of 24 h and validated by instrumental analysis with the result revealing an absence of mercury pollution in the sampling site.

Recently, Troyan et al (2019 arXiv:1908.01534) and Kong et al (2019 arXiv:1909.10482) extended near-room-temperature superconductors family by new yttrium superhydride polymorphs, YH_n (n = 4,6,7,9), which exhibit superconducting transition temperatures in the range of T_c = 210-243 K at pressure of P = 160-255 GPa. In this paper, temperature dependent upper critical field data, B_c2(T), for highly-compressed mixture of YH₄+YH₆ phases (reported by Kong et al 2019 arXiv:1909.10482) is analysed to deduce the ratio of T_c to the Fermi temperature, T_F. Our analysis shows that in all considered scenarios the YH₄+YH₆ mixture has the ratio 0.01 ≤ T_c/T_F ≤ 0.04. As the result, YH₄+YH₆ falls in the unconventional superconductors band in the Uemura plot. It is also found that the characteristic temperature of the order parameter amplitude fluctuations, T_fluc, in the YH₄+YH₆ mixture is only several percent above observed T_c, and thus the superconducting transition in yttrium superhydride polymorphs is fundamentally limited by thermodynamics fluctuations.

Background: Maternal near-miss refers to a situation where a woman who nearly died but survived from severe life-threatening obstetric complications that occurred during pregnancy, childbirth or within 42 days of termination of pregnancy. It has been estimated that up to 9 million women survive obstetric complications every year. According to studies done around the world most mothers suffer from Near Miss due to the factors which includes, low socioeconomic status, patient related, health provider related, and health related and health institution related issues. Objectives: The objective of the study was to determine the proportion of maternal near misses and its associated factors in Selected Public Health Institutions of Keffa, Bench-Maji and Sheka Zones of South Nations Nationalities and Peoples Regional state, South West Ethiopia, 2017. Methodology: Hospital based cross-sectional study design was employed and simple random sampling techniques (Lottery Method) was used to select the study institution and Systematic sampling technique was used to select 845 study participants every 5^th interval. Information was collected by using pre-tested and structured interviewer administered questioner. Using SPSS version 21 software, descriptive statistics and bivariate logistic regression analysis was done and variables with p-value <0.2 were transferred to multivariate analysis and during Multivariate logistic regression analysis Variables with P-value < 0.05 were considered as statistically significant and AOR with 95% CI were used to control for possible confounders and to interpret the result. The results were summarized by tables, graphs and charts. Result: There were 5530 Live Births, 227 Sever Acute Maternal Morbidity cases of this 210 were Maternal Near-Misses cases and 17 were maternal deaths, 364 Maternal Near-Misses Events. The overall Maternal Near-Misses Proportion is 24.85%. The maternal Near-Misses outcome ratio was 41 cases/1,000 live births (LB); mortality ratio was 12.35cases/1 maternal death and 74.8/1000LB of mortality index. Parity, residence, distance of living place from hospital, ANC Follow up, duration of labor, and administrative related problems were found to have statistically significant associations. Conclusion: The proportion of Maternal Near-Misses is relatively high when compared to other regional studies and efforts should be done to lower the near-misses.

We present a comprehensive database of near-shore wind observations that were carried out during the experimental campaign of the RUNE project. RUNE aims at reducing the uncertainty of the near-shore wind resource estimates from model outputs by using lidar, ocean, and satellite observations. Here we concentrate in describing the lidar measurements. The campaign was conducted from November 2015 to February 2016 at the west coast of Denmark and comprises measurements from eight lidars, an ocean buoy and three types of satellites. The wind speed was estimated based on measurements from a scanning lidar performing PPIs, two scanning lidars performing dual synchronized scans, and five vertical profiling lidars, of which one was operating offshore on a floating platform. The availability of measurements is highest for the profiling lidars, followed by the lidar performing PPIs, those peforming the dual setup, and the lidar buoy. Analysis of the lidar measurements reveals good agreement between the estimated 10-m wind speeds, although the instruments used different scanning strategies and measured different volumes in the atmosphere. The campaign is characterized by strong westerlies with occasional storms.

Background: Manoka Health District (MHD), an enclaved archipelago district in Cameroon, is home to about 1,732 under-2 children. Over 90% of these children have not received a single dose of any vaccine. In this paper, we explored the reasons for the high proportion of zero-dose children in this district so as to generate information that policymakers can use to develop context-specific interventions to boast coverage for routine immunization (RI) in this remote fishing island Methodology: We collected qualitative data via key informant interviews (KII) and focused group discussions (FGD) and analyzed it using thematic analysis. Participants for KII were selected using purposive sampling, and a snowballing approach helped to recruit an intermixed population of locals and immigrants for FGDs. Results: MHD is a hard-to-reach zone with a lone health facility that lack a functional cold chain equipment to cover the 47 islets of the district. Diurnal floods, long distance, sea turbulence, infrastructural and resource constraints, and immigrant population without residence permits hinders optimal childhood vaccination. Insufficient community health workers and lack of proper community engagement with feedback loops hamper effective communication and vaccine uptake during campaigns and outreaches. The reasons for vaccination hesitancy included hospital-based vaccination preference over home-based vaccination, fear of post-vaccination fever, rumors, repeated postponement of the vaccination schedules, and refusal by some ethnic group leaders. Conclusion: This study revealed context-specific reasons for zero-dose childhood vaccination status in MHD. These findings should be leveraged to design tailored interventions to raise RI in MHD and similar under-vaccinated communities. Keywords: zero-dose, childhood vaccination, missed communities, Cameroon

New setting is introduced to study failed zero-forcing number and failed zero-forcing neutrosophic-number. Leaf-like is a key term to have these notions. Forcing a vertex to change its color is a type of approach to force that vertex to be zero-like. Forcing a vertex which is only neighbor for zero-like vertex to be zero-like vertex but now reverse approach is on demand which is finding biggest set which doesn’t force. LetNTG : (V,E,σ,μ) be a neutrosophic graph. Then failed zero-forcing number Z(NTG) for a neutrosophic graph NTG : (V,E,σ,μ) is maximal cardinality of a set S of black vertices (whereas vertices in V (G) \ S are colored white) such that V (G) isn’t turned black after finitely many applications of “the color-change rule”: a white vertex is converted to a black vertex if it is the only white neighbor of a black vertex. Failed zero-forcing neutrosophic-number Zn(NTG) for a neutrosophic graphNTG : (V,E,σ,μ) is maximal neutrosophic cardinality of a set S of black vertices (whereas vertices in V (G) \ S are colored white) such that V (G) isn’t turned black afterfinitely many applications of “the color-change rule”: a white vertex is converted to a black vertex if it is the only white neighbor of a black vertex. Failed zero-forcing number and failed zero-forcing neutrosophic-number are about a set of vertices which are applied into the setting of neutrosophic graphs. The structure of set is studied and general results are obtained. Also, some classes of neutrosophic graphs namely path-neutrosophic graphs, cycle-neutrosophic graphs, complete-neutrosophic graphs, star-neutrosophic graphs, bipartite-neutrosophic graphs, and t-partite-neutrosophic graphs are investigated in the terms of maximal set which forms both of failed zero-forcing number and failed zero-forcing neutrosophic-number. Neutrosophic number is reused in this way. It’s applied to use the type of neutrosophic number in the way that, three values of a vertex are used and they’ve same share to construct this number to compare with other vertices. Summation of three values of vertex makes one number and applying it to a comparison. This approach facilitates identifying vertices which form failed zero-forcing number and failed zero-forcing neutrosophic-number. In path-neutrosophic graphs, the set of vertices such that every given two vertices in the set, have distance at least two, forms maximal set but with slightly differences, in cycle-neutrosophic graphs, the set of vertices such that every given two vertices in the set, have distance at least two, forms maximal set. Other classes have same approaches. In complete-neutrosophic graphs, a set of vertices excluding two vertices leads us to failed zero-forcing number and failed zero-forcing neutrosophic-number. In star-neutrosophic graphs, a set of vertices excluding only two vertices and containing center, makes maximal set. In complete-bipartite-neutrosophic graphs, a set of vertices excluding two vertices from same parts makes intended set but with slightly differences, in complete-t-partite-neutrosophic graphs, a set of vertices excluding two vertices from same parts makes intended set. In both settings, some classes of well-known neutrosophic graphs are studied. Some clarifications for each result and each definition are provided. Using basic set not to extend this set to set of all vertices has key role to have these notions in the form of failed zero-forcing number and failed zero-forcing neutrosophic-number. The cardinality of a set has eligibility to form failed zero-forcing number but the neutrosophic cardinality of a set has eligibility to call failed zero-forcing neutrosophic-number. Some results get more frameworks and perspective about these definitions. The way in that, two vertices don’t have unique connection together, opens the way to do some approaches. A vertex could affect on other vertex but there’s no usage of edges. These notions are applied into neutrosophic graphs as individuals but not family of them as drawbacks for these notions. Finding special neutrosophic graphs which are well-known, is an open way to pursue this study. Some problems are proposed to pursue this study. Basic familiarities with graph theory and neutrosophic graph theory are proposed for this article.

Theoretical analysis into the energetics of a novel putative electromagnetic field propulsion device by the author, found that it was able to impart momenergy to the ground state of the electromagnetic field; some rest-energy of the craft was converted to kinetic energy of the craft. Electrical analysis showed that the propulsor was always a net electrical load – if the device accelerated from one frame, then deaccelerated to the original frame, both processes would consume electrical work. The aim of this paper is to look further into this sinking of high-grade electrical energy into the field ground state and to show that an even more pernicious form of 2^nd Law of Thermodynamics exists.

'Huangguan' pear has significant social and economic value, and phosphorus, as one of the three main mineral elements of plants, has an irreplaceable effect on the normal growth of 'Huangguan' pear trees. The objective of this study was to predict the content of phosphorus in the pulp and peel of ‘Huangguan’ pears nondestructively and conveniently by using near-infrared spectroscopy (900–1700 nm) technology. First, twelve algorithms are used to preprocess the original spectral data, and the partial least squares regression algorithm and the gradient boosting regression tree algorithm are used to build a full-band prediction model based on the original spectral data and the processed spectral data. The characteristic wavelengths were extracted using genetic algorithms, followed by establishing a characteristic wavelength prediction model. The prediction accuracy of the models was evaluated according to the coefficient of determination R² and the relative analysis error RPD. The study found that the best prediction model for predicting phosphorus content in the pulp of 'Huangguan' pear was MSC-GA-PLSR, which had R²=0.843 and RPD=1.857 in the modelling set and R²=0.989 and RPD=7.041 in the prediction set. The best prediction model for predicting phosphorus content in the peel of ‘Huangguan’ pear was SG+SNV+FD-GA-PLSR, which had R²=0.991 and RPD=7.470 in the modelling set and R²=0.974 and RPD=4.414 in the prediction set, and the effect was good and met expectations. The results demonstrated that near-infrared spectroscopy could successfully achieve nondestructive detection of phosphorus content in the pulp and peel of 'Huangguan' pears.

In this paper, we propose a methodology for analyzing the near-field coupling between two surface mount device (SMD) inductors using a 3-dimensional electromagnetic (3D-EM) model. To develop the 3D-EM model, we first extract the effective permeability of core magnetic material in the SMD using the loss tangent in the equivalent circuit model. Then the effective permeability is used in the magnetic material for the 3D-EM modeling of SMD inductor. The validity of the proposed 3D-EM model is confirmed by comparing the impedance and S-parameters obtained from both measured and EM-simulated values for the two near-field coupled SMDs. Finally, the near-field coupling effects between the two adjacent SMD inductors are visualized in terms of magnetic coupling path visualization (CPV) using the proposed 3D-EM model, which demonstrates its usefulness for near-field coupling analysis.

Near space environment is the airspace at an altitude of 20 km-100 km, where complex conditions such as low temperature, low pressure, high wind speed and solar radiation exist. As one of the important meteorological parameters, temperature is crucial for space activities, but the influence of the complex environment makes the error of conventional temperature measurement methods large. Therefore, a new microbridge temperature sensor was designed that can reduce solar radiation and achieve a fast response. And through simulation analysis, the three factors influencing the temperature errors of Joule heat, solar radiation heat and aerodynamic heat were investigated. And the influence of temperature error is reduced by optimizing the installation position of the sensor. Through the temperature error model, the error value in the actual measurement value is removed, to realize the high accuracy detection of near-space temperature.

Near-surface humidity (Qa) is a key parameter that modulates oceanic evaporation and influences the global water cycle. Remote sensing observations act as feasible sources for long-term and large-scale Qa monitoring. However, existing satellite Qa retrieval models are subject to apparent uncertainties due to model errors and insufficient training data. Based on in situ observations collected over the China Seas over the last two decades, a deep learning approach named Ensemble Mean of Target deep neural networks (EMTnet) was proposed to improve the satellite Qa retrieval over the China Seas for the first time. The EMTnet model outperforms five representative existing models by nearly eliminating the mean bias and significantly reducing the root-mean-square error in satellite Qa retrieval. According to its target deep neural networks selection process, the EMTnet model can obtain more objective learning results when the observational data are divergent. The EMTnet model was subsequently applied to produce a 30-year monthly gridded Qa data over the China Seas. It indicates that the climbing rate of Qa over the China Seas under the background of global warming are probably underestimated by current products.

As solar energy is a low-cost and clean energy source, there has been a great deal of interest in how to harvest it. To absorb solar energy efficiently, we have designed a broadband metamaterial absorber based on the principle of Fabry–Pérot (FP) cavity and surface plasmon resonances (SPRs). We propose a broadband perfect absorber consisting of a four-layer structure of silica-tungsten-silica-titanium (SiO2-W-SiO2-Ti) for the incident light wavelength range of 300–2500 nm. The structure achieves perfect absorption of incident light in the wavelength range of 351.8–2465.0 nm (absorption >90%), with an average absorption of 96.3%. The advantage of our proposed structure is that it combines the characteristics of both high and broadband absorption and has a high overall absorption efficiency for solar radiation. It is also independent of polarization and insensitive to incident angle. We investigated how absorption was affected by different structures, materials, geometrical parameters, and refractive indices for different dielectric materials, and we explored the reasons for high absorption. This structure is refractory and ultra-thin, and it offers a good trade-off between bandwidth and absorption. It therefore has premium application prospects and value.

The use of crime mapping has been used by the police to inform deployment of resources for many decades. Such approaches are commonly used to underpin crime control strategies designed to prevent or reduce acquisitive crimes such as domestic burglary. In recent decades there has been a shift away from simple hot spot identification to more complex geospatial mapping methodologies, such as near repeat analysis which was developed through research regarding burglary victimisation. One of these newly emerging methodologies is built upon the ecological, optimal forager theory (OFT). Research using this theory to examine domestic burglary offending intimated potential for positive results in predicting areas at risk of future crime. This led to a number of police services using crime analysis methodologies built upon OFT to underpin their deployment of resources in an effort to prevent or reduce domestic burglary through increased capable guardianship. However, to date, there has been no detailed examination of how the police services implemented such approaches. As such, this study seeks to fill this gap by examining OFT strategies implemented within 5 police services. By interviewing participants directly involved in the programs the study gathers views and perspectives of its relative success. As a result, we identify that participants felt the strategies produced limited impact on recorded burglary crime. We discuss how despite some positive by-products of the strategies, failure to comprehensively apply the theoretical foundations of OFT, and a variety of implementation failures have undermined the various programs, ultimately impacting their effectiveness.

Understanding how the deformed bed topography induced by near-bank vegetation impacts the hydrodynamics is significant for understanding the maintenance condition of bed morphology and further fluvial evolution. This issue has rarely been addressed by current studies. This study with a 2D hydro-morphological model investigates the hydrodynamics over flat and deformed beds with a near-bank vegetation patch. By varying the patch density, the generalized results show that the hydrodynamics for the deformed bed differs a lot from those for the flat bed. It is found that deformed bed topography leads to an apparent decrease in longitudinal velocity and bed shear stress in the open region and longitudinal surface gradient for the entire vegetated reach. However, the transverse flow motion and transverse surface gradient in the region of the leading edge and trailing edge is enhanced or maintained, suggesting the strengthening of secondary flows. Interestingly, the deformed bed topography tends to alleviate the turbulent effect caused by the junction-interface horizontal coherent vortices, indicating that the turbulence-induced flow mixing is highly inhibited by the deformed bed. Alternatively, the enhanced secondary flows might provide compensation for the flow mixing for the deformed bed, confirmed by a faster recovery of the redistributed water discharge for the vegetated and open regions to the normal value (50%). The interior flow adjustment through the patch for the deformed bed requires a shorter distance, which links the vegetative drag length with a logarithmic relation. The tilting bed topographic effect in the open region to accelerate the flow may account for the faster flow adjustment.

Chloroquine was among the first of several effective drug treatments against malaria until the onset of chloroquine resistance. In light of diminished clinical efficacy of chloroquine as an antimalarial therapeutic, there is potential in efforts to adapt chloroquine for other clinical applications, such as in combination therapies and in diagnostics. In this context, we designed and synthesized a novel asymmetrical squaraine dye coupled with chloroquine (SQR1-CQ). In this study, SQR1-CQ was used to label live Plasmodium falciparum (P. falciparum) parasite cultures of varying sensitivities towards chloroquine. SQR1-CQ positively stained ring, mature trophozoite and schizont stages of both chloroquine–sensitive and chloroquine–resistant P. falciparum strains. In addition, SQR1-CQ exhibited significantly higher fluorescence, when compared to a chloroquine-BODIPY (borondipyrromethene) conjugate. We also achieved successful SQR1-CQ labelling of P. falciparum directly on thin blood smear preparations. Drug efficacy experiments measuring half-maximal inhibitory concentration (IC50) showed lower concentration of effective inhibition against resistant strain K1 by SQR1-CQ compared to conventional chloroquine. Taken together, the versatile and highly fluorescent labelling capability of SQR1-CQ and promising preliminary IC50 findings potentiates it to be further developed as a promising diagnostic bioimaging tool with drug efficacy against chloroquine-resistant P. falciparum.

This paper explores the potential of using the SAM segmentator to enhance the segmentation capability of known methods. SAM is a promptable segmentation system that offers zero-shot generalization to unfamiliar objects and images, eliminating the need for additional training. The open-source nature of SAM on GitHub allows for easy access and implementation. In our experiments, we aim to improve the segmentation performance by providing SAM with checkpoints extracted from the masks produced by DeepLabv3+, then merging the segmentation masks provided by these two networks. Additionally, we examine the \enquote{oracle} method (as upper bound baseline performance), where segmentation masks are inferred only by SAM with checkpoints extracted from ground truth. In addition, we tested in the CAMO datasets an ensemble of PVTv2 transformers; combining the ensemble and SAM yields state-of-the-art performance in that dataset. The results of our study provide valuable insights into the potential of incorporating the SAM segmentator into existing segmentation techniques. We release with this paper the open-source implementation of our method.

Valorization of food and fruit wastes has the potential for the production of sustainable energy and biochemicals. Approximately 70% of the weight of the original jackfruit (Artocarpus heterophyllus L.) fruit is lost during processing as waste in the form of peeled skin and core, both of which have not been utilized and, thus contribute to disposal as well as pollution issues. The major components, cellulose, and hemicellulose, can be biologically transformed easily into bioenergy sources like ethanol, methanol, and butanol; valuable phenolics and biotechnological products like pectin, citric acid, bromelain, ferulic acid, and vanillin; and many other products. These residues can also be utilized as essential sources for the biological transformation process leading to the production of numerous products with added value, such as phenolic antioxidants, phenolic flavor compounds, and organic acids. Thus, the value addition of jackfruit waste can support the sustainable solution towards food and nutritional security. In this way, zero waste can be achieved through novel biorefineries which are critically highlighted in this paper. Furthermore, novel technologies for the conversion of jackfruit wastes are summarized with recent findings.

Current State-of-the-Art (SotA) chatbots are able to produce high quality sentences, handling different conversation topics, and larger interaction times. Unfortunately, the generated responses highly depend on the data on which they have been trained, the specific dialogue history and current turn used for guiding the response, the internal decoding mechanisms, ranking strategies, among others. Therefore, it may happen that for semantically similar questions asked by users, the chatbot may provide a different answer, which can be considered as a form of hallucination or produce confusion in long-term interactions. In this research paper, we propose a novel methodology consisting of two main phases: a) hierarchical automatic detection of topics and subtopics in dialogue interactions using a Zero-Shot learning approach, and b) detecting inconsistent answers using K-Means and the Silhouette coefficient. To evaluate the efficacy of topic and subtopic detection, we used a subset of the DailyDialog dataset and real dialogue interactions gathered during the Alexa Socialbot Grand Challenge 5 (SGC5). The proposed approach enables detecting up to 18 different topics and 102 subtopics. For the purpose of detecting inconsistencies, we manually generate multiple paraphrased questions and employ several pre-trained SotA chatbot models to generate responses. Our experimental results demonstrate a weighted F-1 value of 0.34 for topic detection, a weighted F-1 value of 0.78 for subtopic detection in DailyDialog, then 81% and 62% accuracy for topic and subtopic classification in SGC5; finally, to predict the number of different responses, we obtained a mean squared error (MSE) of 3.4 when testing smaller generative models and 4.9 in recent large language models.

Despite the increase in popularity of Zero Waste (ZW) concept, the successful implementation of this concept in waste management is still facing many challenges. The plastic recycling rate in Australia is currently only about 9.4%, which could leave up to 90.6% of plastic consumption being sent to landfills. The state of Victoria (in Australia) has proposed an ambitious plan to upgrade its waste and recycling system and to divert about 80% of waste from landfills by 2030. The aim of this research is to study Victoria’s current waste management plan and to develop a simulation model to assess the feasibility of it achieving zero plastic waste by 2035. In this direction, a fundamental knowledge of global ZW implementation needs to be acquired in order to understand the challenges, obstacles, and uncertainties in achieving ZW target. A simulation model is established using a method called double baselines. This method was developed as an improvisation to address the limitation of data availability for the model development. The model will run on 4 scenarios including one from Victoria’s current plan. Outcomes from the model are produced in comparative charts covering 6 key considerations including the rates of plastic consumption, waste to landfill, diversion, recycling, relative accumulative cost and effort. The findings of this study pointed out that Victoria’s current plan are feasible for its goal and presented with opportunities for improvement especially towards zero plastic waste. Besides, study results also reveal that the Victoria’s current plan to achieve 80% diversion rate by 2030 is possible but the zero plastic waste target by 2035 is less likely to happen.

The zero velocity update(ZUPT) algorithm is the core of a foot-mounted pedestrian navigation system. The zero velocity detection method is the premise and guarantee of the effective application of the ZUPT algorithm. To make ZUPT work properly, it is necessary to detect zero velocity intervals correctly. The detection accuracy of the existing zero velocity detection methods is easy to be affected by users and environment. A novel zero velocity detection method based on the plantar pressure is proposed in this paper, which has higher detection accuracy and better environmental adaptability. First, the paper analyzes the motion characteristics of foot during walking. Second, the inherent relationship between the plantar pressure and the gait change during walking is studied based on the pressure sensor. Then, the model of the zero velocity detection method using the plantar pressure is established. Finally, the indoor and outdoor multi-scene experiments show that this method not only has a high detection accuracy, but also has good adaptability to users and walking environment.

In this work, we investigated for the first time the complexation of sepiapterin (SP), the natural precursor of the natural essential cofactor tetrahydrobiopterin, that displays mild water-solubility and short biological half-life, with the hydrophobic triacetyl-β-cyclodextrin (TAβCD) to improve its encapsulation within methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone) (mPEG-PCL) nanoparticles. First, TAβCD-SP complexes were produced by spray-drying of TAβCD/SP binary solutions by utilizing the Nano Spray Dryer B-90 HP. Then, dry powders were characterized by differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR) and transmission and scanning electron microscopy (SEM and TEM, respectively) and compared to the complex components and physical mixtures (PMs). Next, SP was encapsulated within methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone) (mPEG-PCL) nanoparticles by nanoprecipitation of a SP/TAβCD complex/mPEG-PCL solution. In addition to complex nanoencapsulation, we assessed encapsulation of pure SP by nanoprecipitation with an intermediate step, which comprised the co-drying of SP, TAβCD and mPEG-PCL copolymer solution in organic solvent; this step aimed to promote the formation of molecular interactions between SP, TAβCD and the PCL blocks in the copolymer. SP-loaded mPEG-PCL nanoparticles were characterized by dynamic light scattering (DLS) and SEM. Nanoparticles with size of 74-75 nm and small polydispersity index (PDI <0.1) were obtained when SP-TAβCD equimolar spray-dried complex was used for nanoencapsulation, and SEM analysis indicated the absence of free SP crystals. Moreover, the encapsulation efficiency (%EE) and drug loading (DL) were 85% and 2.6%, respectively, as opposed to those achieved with pure SP encapsulation (14% and 0.6%, respectively). Overall, our results confirm that spray-drying of SP/TAβCD solutions at the appropriate molar ratio leads to the hydrophobization of the relatively hydrophilic SP molecule, enabling its encapsulation within mPEG-PCL nanoparticles.

Given a fuzzy normed space $ \left( X,N \right) $‎, ‎we will introduce the notion of fuzzy near best approximation within a relative distance $ \rho \geq 0 $‎. ‎Some basic properties are characterized and also many examples for illustration are presented‎.

Earth’s near space is a region between 20 and 100 km above sea level, which is characterized by low temperature, low atmospheric pressure, harsh radiation, and extreme dryness. These conditions are analogous to the surface of Mars and the atmosphere of Venus, and thus make it a unique natural lab for astrobiologists. To address the important astrobiological questions of the effects of the near space environmental conditions on biology and of the survival strategies of representative organisms in this planetary analog, teams from the Chinese Academy of Sciences have developed a scientific balloon platform named the Chinese Academy of Sciences Balloon-Borne Astrobiology Platform (CAS-BAP) and carried out a series of experiments in lower near space since 2019. Here, we describe the Biological Samples Exposure Payload (BIOSEP) loaded on CAS-BAP with respect to its structure and function. The primary role of BIOSEP is to expose biological/chemical samples to the planetary analog environments of Earth’s lower near space. Exposed samples will be returned to laboratories for morphological, physiological, chemical, and genetic analyses. The development of BIOSEP and associated biological exposure experiments will improve our understanding of the livelihood of potential Mars lives and the potential habitability of the atmosphere regions of other planets in the Solar System and beyond.

Introduction: Successful R0 resection is crucial for the survival of patients with primary liver cancer (PLC) or liver metastases. Up to date, surgical resection lacks a sensitive, real-time intraoperative imaging modality to determine R0 resection. Real-time intraoperative visualization with near-infrared light fluorescence (NIRF) using indocyanine green (ICG) may have the potential to meet this demand. This study evaluates the value of ICG visualization in PLC and liver metastases surgery regarding R0 resection rates. Materials and Methods Patients with PLC or liver metastases were included in this prospective cohort study. ICG 10mg was administered intravenously 24 hours before surgery. Real-time intraoperative NIRF visualization was made with the SpectrumTM Fluorescence Imaging Camera System. First, all liver segments were inspected with the fluorescence imaging system and intraoperative ultrasound for identification of the known tumor as well as additional lesions, compared to preoperative MRI. PLC, liver metastases, and additional lesions were then resected according to oncological principles. Of all resected specimens the resection margins were analyzed with the fluorescence imaging system for ICG positive spots right after resection. Histology of additional detected lesions as well as ICG fluorescence compared to histological resection margins were assessed. Results Of the 66 included patients median age was 65.5 years (IQR 58.7 - 73.9), 27 (40.9%) were female and 18 (27.3%) were operated laparoscopically. Additional ICG positive lesions were detected in 23 (35.4%) patients of which nine (29%) were malignant. In patients with no fluorescent signal at the resection margin, R0 rate was 93.9%, R1 rate was 6.1%, and R2 rate was 0% compared to a ICG positive resection margin with a R0 rate of 64.3%, R1 rate of 21.4%, and R2 rate of 14.3% (p=0.005). One and two year overall survival were 95.2% and 88.4%, respectively. Conclusion The here presented study provides significant evidence that ICG NIRF guidance helps to identify R0 resection intraoperatively. This offers a true potential to verify radical resection and improve patients´ outcome. Furthermore, implementation of NIRF guided imaging in liver tumor surgery allows to detect a considerable amount of additional malignant lesions.

The optical properties and physiology of biological tissue, as well as how near-infrared (NIR) light interacts with the tissue, both play a significant role in interpreting the tissue probing optical measurements, and in solving the inverse problem of near-infrared spectroscopy (NIRS)-based medical imaging modalities such as diffuse optical tomography and functional near-infrared spectroscopy. This paper discusses the optical properties of tissue, specifically in the NIR wavelength range, which influence NIRS measurements in NIRS-based medical imaging. There is an easy-to-understand explanation given in this paper of the NIR light-tissue interaction phenomenon. The mathematical explanation, the processes involved in the interaction, and the rationale for a few approximations are described. Various types of chromophores present in the tissue, their composition in the tissue, and how these chromophores overall affect the scattering and absorption of NIR light are presented. The absorption spectra of these chromophores are shown. Finally, the paper concludes with the author’s perspective on two NIRS-based medical imaging modalities, diffuse optical tomography, and functional near-infrared spectroscopy.

Dermal water content is an important biophysical parameter in preserving skin integrity and preventing skin damage. Traditional electrical-based and open-chamber evaporimeters have several well-known limitations. In particular, such devices are costly, sizeable, and only provide arbitrary outputs. They also do not permit continuous and non-invasive monitoring of dermal water content, which can be beneficial for various consumer, clinical and cosmetic purposes. We report here on the design and development of a digital multi-wavelength optical sensor that performs continuous and non-invasive measurement of dermal water content. In-silico investigation on porcine skin was carried out using the Monte Carlo modelling strategy to evaluate the feasibility and characterise the sensor. Subsequently, an in-vitro experiment was carried out to evaluate the performance of the sensor and benchmark its accuracy against a high-end, broad band spectrophotometer. Reference measurements were made against gravimetric analysis. The results demonstrate that the developed sensor can deliver accurate, continuous, and non-invasive measurement of skin hydration through measurement of dermal water content. Remarkably, the novel design of the sensor exceeded the performance of the high-end spectrophotometer due to the important denoising effects of temporal averaging. The authors believe, in addition to wellbeing and skin health monitoring, the designed sensor can particularly facilitate disease management in patients presenting diabetes mellitus, hypothyroidism, malnutrition, and atopic dermatitis.

Near-Infrared Spectroscopy (NIRS) has been used to measure muscle mitochondrial capacity. The current method requires as many as 22 short ischemic occlusions to generate a recovery curve for mitochondrial capacity. PURPOSE: To determine the effectiveness of using a 6-occlusion analysis protocol to study muscle mitochondrial capacity. METHOD: Two independent, unidentified data sets were analyzed (bicep n=48, forearm n=41) from previous studies using a NIRS device (Artinis, Ltd.). Both data sets had two recovery tests that included 22 ischemic occlusions. A recovery rate used to indicate mitochondrial capacity was calculated two different ways (simultaneously). Each sample was analyzed with a MATLAB program; with a curve-fit for the 22 ischemic occlusions and curve matching for the first six ischemic cuffs and an end resting value. The two resulting rate constants were compared using correlations, both for the two data sets, good and bad fitting data, using the best 5 of 6 points for the 6 cuff approach. RESULTS: The rate constants were not significantly different between the 22 cmuff and 6 cuff for the total data sets: bicep (1.43+0.32min^-1, 1.44+0.35min^-1, p=0.56), forearm (1.94+0.42min^-1, 1.95+0.44min^-1, p=0.76). The average bicep rate constants, when compared to each other, had an equation of y=1.07x-0.09, R²=0.90. The average forearm rate constants, when compared to each other, had an equation of 0.98x+0.02, R²=0.93. CONCLUSIONS: The 6-Cuff analysis provided the same results as the longer 22-cuff. The 6-cuff approach is both shorter in time and uses less ischemic occlusion periods, increasing the practicality of the NIRS mitochondrial capacity test.

NIRS uses the relative absorption of light at 850nm and 760nm, to determine skeletal muscle oxygen saturation. Previous studies have used the ratio of both signals to report muscle oxygen saturation. Purpose: To evaluate the different approaches used to represent muscle oxygen saturation, and to evaluate the pulsations of the O₂heme and Heme signal. Method: Twelve participants, ages 20-29years were tested on the forearm flexor muscles using continuous wave NIRS at rest. Measurements were taken during 2-3mins rest, during physiological calibration (5-minuts Ischemia) and during reperfusion. Results: There was a significant difference in pulse size between O₂heme and Heme signal at the three locations (p < 0.05). Resting oxygen saturation was 58.8+9.2%, 69.6+3.9%, and 89.2+6.9% when calibrated using O₂heme, TSI, and Heme, respectively. Conclusion: The difference in magnitude of O₂heme and Heme pulse with each heartbeat might suggest different anatomical locations of these signals, which propose calibrating with just one of the signals instead of the ratio of both. Calculations of physiological calibration must account for increased blood volume in the tissue, because of the changes in blood volume which appear to be primarily from the O₂heme signal. Resting oxygen levels calibrated with Heme agrees with theoretical oxygen saturation.

The Inverted F Antenna (IFA) with the parasitic element on a finite conducting plane is proposed in the range frequency of 0.1 to 5.5 GHz and its characteristics are analyzed numerically. In this research, the parasitic element and the main IFA are investigated to obtain the resonance frequency for multiband operation purposes. The parasitic element is placed beneath adjusted to the main IFA to derive more frequency bands. The distance between the parasitic element and main horizontal element extremely affects the performance of the IFA. It is found that when the parasitic element is located closer to the conducting plane, this element is coupled by the current on the conducting plane. Consequently, the return loss bandwidth becomes narrower. Therefore, the gain of the proposed IFA becomes a bit higher. The antenna gain is about 8.21 dB at band #3 (λ_1.747), 7.43 dB at band #5 (λ_2.967) and 8.82 dB at band #6 (λ_4.023). This occurs when the calculation condition is antenna height h1 = 23 mm, h2 = 21 mm, horizontal antenna elements L = 173.2 mm, L1 = 140.9 mm and Lp = 152 mm, shorted element Ls = 30.7 mm, the distance between parasitic element and shorted element pyl = 5 mm. While the size of conducting plane is considered pxp+pxm by pyp+pym as 57.5+57.5 mm by 200+50 mm. In the numerical analysis, the electromagnetic simulator WIPL-D based on Method of Moment is used. The results show that the proposed IFA has UHF and SHF channel receiver which are suitable for advanced wireless service (band #3), mobile phones, Bluetooth, maritime service, radiolocation service (band #5) and radars, mobile phones, commercial wireless LAN (band #6).

Aiming to reveal the kinetic characteristics of ceramic ball grinding of fine magnetite comprehensively, two types of ceramic balls ground with the same filling rate and total weight as steel balls were researched. The results show that the breakage rate of ceramic ball grinding is only half of that of steel ball grinding with the same media filling rate. With the same total media weight and the feed size less than 0.212 mm, the breakage rate of the ceramic ball grinding approaches the steel ball grinding and is 21.43% higher than that of the steel ball grinding. The main crushing form of magnetite changed from impact to abrasion in ceramic ball grinding compared with steel ball grinding, which significantly affected the value of the zero-order output constant a. Consequently, there is a noticeable difference in the variation of the parameter β related to the fines generation rate of the ceramic ball grinding compared with the steel ball grinding.

Internet of Things includes all connected objects from small embedded systems with low computational power and storage capacities to efficient ones, as well as moving objects like drones and autonomous vehicles. The concept of Internet of Everything expands upon this idea by adding people, data and processing. The adoption of such systems is exploding and becoming ever more significant, bringing with it questions related to the security and the privacy of these objects. A natural solution to data integrity, confidentiality and single point of failure vulnerability is the use of blockchains. Blockchains can be used as an immutable data layer for storing information, avoiding single point of failure vulnerability via decentralization and providing strong security and cryptographic tools for IoE. However, the adoption of blockchain technology in such heterogeneous systems, containing light devices, presents several challenges and practical issues that need to be overcome. Indeed, most of the solutions proposed to adapt blockchains to devices with low resources confront difficulty in maintaining decentralization or security. The most interesting are probably the Layer 2 solutions which build offchain systems strongly connected to the blockchain. Among these, zk-rollup is a promising new generation of Layer 2/off-chain schemes which can remove the last obstacles to blockchain adoption in IoT, or more generally, in IoE. Despite their promises illustrated by recent systems proposed by startups and private companies, very few scientific publications explaining or applying this barely-known technology have been published, especially for non-financial systems. In this context, the objective of our paper is to fill this gap for IoE systems in two steps. We first propose a synthetic review of recent proposals to improve scalability including onchain (consensus, blockchain organization, ...) and offchain (sidechain, rollups) solutions and we demonstrate that zk-rollups are the most promising ones. In a second step, we focus on IoE by describing several interesting features (scalability, dynamicity, data management, ...) that are illustrated with various general IoE use cases.

Mill scale is the by-product of iron and steel industry. It can be recycled via sinter plant or solid as sinter feed materials. 85 to 90% of the constituent particles are more than 0.008 inches. The iron content is near around 70 %, with a very small amount of alkaline compounds and non-ferrous metals. Mill scale is polluted and contaminated with lubricants, oils and greases from the equipment. In this experiment for recovering of oil from mill scale, it is treated with three different methods. Then all methods were compared according to the ability of oil elimination and iron recovered. After washing and boiling with surfactants, large amount of polluted waste water becomes a problem for environment so this wastewater was utilized for making of Microbial Fuel Cells (MFCs), production of electricity in MFC depends on the biodegradation of organic materials, so different waste were added in wastewater for making MFC. The remaining of MFC was converted in bioethanol, biodiesel and biofertilizer. So this research is economical and environmentally friendly and fulfilled the important aspect of green environment with zero waste. It will be a mile stone in the research of metallurgy, environmental engineering, recycling technology and zero waste management.

Zero-Knowledge Proofs ZKP provide a reliable option to verify that a claim is true without giving detailed information other than the answer. A classical example is provided by the ZKP based in the Graph Isomorphism problem (GI), where a prover must convince the verifier that he knows an isomorphism between two isomorphic graphs without publishing the bijection. We design a novel ZKP exploiting the NP-hard problem of finding the algebraic ideal of a multivariate polynomial set, and consequently resistant to quantum computer attacks. Since this polynomial set is obtained considering instances of GI, we guarantee that the protocol is at least as secure as the GI based protocol.

Multi-channel and multi-parameter near-infrared spectrometers (NIRS) have gradually become a new research direction and hot spot due to their ability to provide real-time, continuous, comprehensive indicators of multiple parameters. However, multi-channel and multi-parameter detection may lead to crosstalk between signals. There is still a lack of benchmarks on the evaluation of reliability, sensitivity, stability and response consistency of the NIRS instrument. In this study, a set of test methods (the ink drop test, multi-channel crosstalk test and multi-parameter crosstalk test) for analysis crosstalk and verifying the reliability of NIRS were conducted to test experimental verification on a multi-channel (8-channel), multi-parameter (4-parameter) NIRS instrument independently developed by our team. Results show that these tests can be used to analyze the signal crosstalk and verify the reliability, sensitivity, stability and response consistency in the NIRS instrument. This study contributes to the establishment of benchmarks for the NIRS instrument crosstalk and reliability testing. These novel tests have the potential to become the benchmark for the NIRS instrument reliability testing.

A non-destructive analysis of proximate parameters (moisture content, MC; volatile matter, VM; fixed carbon, FC; and ash content) for a variety of chipped and ground biomasses was investigated through a combination of thermogravimetric analysis (TGA) and near-infrared spectroscopy (NIRS) with partial least squares regression (PLSR). In this study, the thermogravimetric method was employed as a tool to determine the proximate analysis data of biomass samples through TG and DTG curves, which were generated by tracking changes in biomass mass loss over time or temperature. NIRS non−destructively scanned the chipped biomass in diffuse reflectance while ground biomass using transflectance mode, covering the wavenumber range of 3594.87 to 12,489.48 cm−1. The PLSR−based models: Full−PLSR, genetic algorithm (GA)−PLSR, successive projection algorithm (SPA)−PLSR, the spectral multi−preprocessing (MP) PLSR− 5 range method, and the MP PLSR−3 range method were developed. Model performance was assessed, compared, and selected based on the coefficient of determination in the prediction set (R2P), root mean square error in the validation set (RMSEP), and the ratio of prediction to deviation (RPD). Based on the comprehensive analysis of model performance, MC and FC models of chip biomass have demonstrated satisfactory performance which makes it applicable cautiously in any application, including research. The optimum models for MC and FC in chip biomass were constructed using GA−PLSR with 2nd derivative and Full−PLSR with a constant offset, resulting in R2P values of 0.8654 and 0.8773, RMSEP values of 0.85% and 2.12%, and RPD values of 2.9 and 3.0, respectively. Other parameters such as MC and FC in ground biomass as well as VM and ash content in both chip and ground biomass were found suitable for rough screening. The sensitivity of the selected model was assessed by calculating the limit of quantification (LOQ), and the results indicated that the calculated LOQ values for VM in both chip and ground biomass and FC in chip biomass are lower than the minimum reference values used during model development, signifying a high level of sensitivity. However, for the remaining parameters, the LOQ values surpass the established minimum reference value, suggesting the model could not predict the future samples with reference value lower than the calibration range. Nevertheless, enhancing the models by incorporation an ample number of representative biomass samples and consistently validating the models with unknown samples is imperative to ensure accurate predictions.

Saudi Arabia is a prominent producers of dates, with 1.6 million tons annually. There is a need to evaluate physical properties and quality of fruits non-destructively and then be modeled and predicted throughout the storage period. The aim of the current study was to generate a quality index (Qi) and Near-infrared spectra (NIR) models non-destructively to predict properties of Barhi dates fruits including objective and sensory evaluations. The engineering properties of Barhi dates were measured and modeled with quality index (Qi) based on NIR of fresh Barhi fruits (hardness, color, TSS, pH, and sensory evaluations) and during storage in cold, ambient, and controlled at-mosphere (CA) for up to four months. The prediction of Qi is non- destructively based on NIR utilizing PLSR and ANN data analysis. The results showed that the Qi generated corresponds with high precision to the characteristics of the examined fruits through the duration of the storage period with R2 of 0.96. The NIR spectrum proves to be an efficient method to evaluate the Barhi fruits' quality index. where ANN was found to be more suitable than PLSR analysis. Thus, NIR can be utilized to accurately predict the Qi of fruits quality effectively throughout the handling, processing, transporting, storage, and retail sector supply chain.

As an important organelle in eukaryotic cells, Golgi apparatus is responsible for processing and transporting proteins and lipids in cells. Precise monitoring the status of Golgi apparatus by targeting fluorescence imaging technology is of enormous importance but remains an attractive yet dramatically challenging task. In this study, we report the construction of the first Golgi apparatus targeted sensor with bright near-infrared fluorescence, termed as Golgi-Pdots. As a start point of our investigation, hydrophobic CDs with bright NIR fluorescence at 674 nm (fluorescence quantum yield : 12.18%), narrow emission band of 23 nm, and excellent stability were facilely prepared from Magnolia Denudata flowers through an ultrasonic method. Incorporating the CDs into a polymer matrix modified with Golgi-targeting molecules can produce the water-soluble Golgi-Pdots, which showed high colloidal stability and similar optical properties as compared to CDs. Further studies revealed that the Golgi-Pdots showed good biocompatibility and Golgi-targeting ability. Based on these fascinating properties, Golgi-Pdots have been successfully used for long term bioimaging of Golgi apparatus inside live cells.

Recently, the interest in silicon-based detectors capable of detecting single photons in the near-infrared is growing mainly due to LiDAR applications, autonomous driving in particular. Silicon single-photon avalanche diodes are one of the most interesting single-photon NIR technology available on the market, nevertheless, their efficiency is hindered by the low absorption coefficient of Si in the NIR. The idea is the integration of CMOS-compatible nanostructures, specifically, silver grating array supporting Surface Plasmons Polaritons (SPPs), to confine superficially the incoming NIR photons and therefore increase photons probability to generate an electron-hole pair. The plasmonic silver array is geometrically fine-tuned using time domain simulation software to achieve maximum detector performance at 950 nm. Then, the plasmonic silver array is integrated by means of the focused ion beam technique on the detector. Finally, the integrated detector is electro-optically characterized, demonstrating a quantum efficiency of 13 at 950 nm, 2,2 times more than the reference detector. This result suggests the production of a device capable of detecting single NIR photons, at a very low cost and compatible with CMOS, thus integrable on existing technology platforms.

A major limitation of near-infrared spectroscopy (NIRS) is its high sensitivity to the scalp and low sensitivity to the brain of adult humans. In the present work we use multi-distance hyperspectral NIRS (hNIRS) to investigate the optimal source-detector distances, range of wavelengths, and analysis techniques to separate cerebral responses to 30-s breath holds (BHs) from the responses in the superficial tissue layer in healthy adult humans. We observed significant responses to BHs in the scalp hemodynamics. Cerebral responses to BHs were detected in the cytochrome C oxidase redox (rCCO) at 4 cm without using data from the short-distance channel. Using the data from the 1 cm channel in the two-layer regression algorithm showed that hemodynamic and rCCO responses also occurred at 3cm. We found that the waveband 700-900 nm was optimal for the detection of cerebral responses to BHs in adults.

Lanthanide-doped upconversion nanoparticles (UCNPs) are promising bioimaging nanoprobes due to their excellent photostability. As one of the most commonly-used lanthanide activators, Tm3+ ions have perfect ladder-type electron configuration and can be directly excited by bio-friendly near-infrared-II (NIR-II) wavelengths. Here, the emission characteristics of Tm3+-doped nanoparticles under laser excitations of different near-infrared-II wavelengths were systematically investigated. The 1064 nm, 1150 nm and 1208 nm lasers are proposed to be three excitation strategies with different response spectra of Tm3+ ions. Particularly we found that 1150 nm laser excitation enables intense three-photon 475 nm emission, which is nearly 100 times stronger than that excited by 1064 nm excitation. We further optimized the luminescence brightness after investigating the luminescence quenching mechanism of bare NaYF4:Tm (1.75%) core. After growing inert shell, ten-fold increase of emission intensity was achieved. Combining the advantages of NIR-II wavelength and the higher-order nonlinear excitation, a promising facile excitation strategy was developed for the application of thulium-doped upconversion nanoparticles in single nanoparticle imaging and cancer cell microscopic imaging.

In recent years graphene has attracted much interest due to its unique properties of flexibility, strong light-matter interaction, high carrier mobility and broadband absorption. In addition, graphene can be deposited on many substrates including silicon with which is able to form Schottky junctions opening the path to the realization of near-infrared silicon photodetectors based on the internal photoemission effect where graphene play the role of the metal. In this work, we review the very recent progress of the near-infrared photodetectors based on Schottky junctions involving graphene. This new family of device promises to overcome the limitations of the Schottky photodetectors based on metals showing the potentialities to compare favorably with germanium photodetectors currently employed in silicon photonics.

A fast and effective determination method of different species of vegetable seeds oil is vital in the plant oil industry. The near-infrared reflectance spectroscopy (NIRS) method was developed in this study to massively analyze the oil and moisture contents of Camellia gauchowensis Chang and C. semiserrata Chi seeds kernels. In the prediction models of NIRS, the levels of accuracy obtained were sufficient for C. gauchowensis Chang and C. semiserrata Chi, the correlation coefficient of which oil were 0.983 and 0.962, respectively, while which of moisture were 0.937 and 0.907, respectively. The near infrared spectrum of crush seeds kernels was more precise compared to intact kernels. Based on the calibration models of the two Camellia species, the NIRS predictive oil contents of C. gauchowensis Chang and C. semiserrata Chi seeds kernels were 48.71 ± 8.94% and 31.71 ± 7.39%, respectively, and the NIRS predictive moisture contents were 4.39 ± 1.08% and 3.49 ± 0.71%, respectively. Compared with the traditional chemical measurement, the rapid, precise measurement of oil and moisture of C. gauchowensis Chang and C. semiserrata Chi seeds kernels can be actualized by NIRS method.

We attempted to apply the optoelectronic sensor entitled 'OPT101' in intensive care unit clinics, based on its optoelectronic response characteristics in near-infrared wavelength range and near-infrared spectroscopy principle. The successful novel applications in our lab include early-diagnosis and therapeutic effect tracking of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. This study also expects further improvements of the detector in noninvasive clinical applications.

The pursuit of Artificial Intelligence (AI) that emulates human cognitive processes is a cornerstone of ethical AI development, ensuring that emerging technologies can integrate seamlessly into societal frameworks requiring nuanced understanding and decision-making. Zero-Shot Instance Retrieval (ZSIR) stands at the forefront of this endeavour, potentially providing a robust platform for AI systems, particularly large visual language models, to demonstrate and refine cognition-aligned learning without the need for direct experience. In this paper, we critically evaluate current cognition alignment methodologies within traditional zero-shot learning paradigms, using visual attributes and word embedding generated by large AI models. We propose a unified similarity function that quantifies the cognitive alignment level, bridging the gap between AI processes and human-like understanding. Through extensive experimentation, our findings illustrate that this similarity function can effectively mirror the visual-semantic gap, steering the model towards enhanced performance in zero-shot instance retrieval. This work not only benchmarks the cognition alignment of AI, but also sets a new precedent for the development of visual language models attuned to the complexities of human cognition.}

We study the coupling of two topologcal subsystems in distinct topological states, and show that it leads to a precursor behavior of the topological phase transition in the overall system. This behavior is solely determined by the symmetry classes of the subsystem Hamiltonians and coupling terms, and is marked by the persistent existence of subgap states within the bulk energy gap. By investigating the critical current of Josephson junctions involving topological superconductors, we also illustrate that such subgap states play crucial roles in physical properties of nanoscale devices or materials.

Super-resolution technology is important not only in bio-related fields but also in nanotechnology, particularly in the semiconductor industry, where fine patterning is required and super-resolution is essential. However, observing microstructures beyond the diffraction limit proposed by Abbe and Rayleigh is considered impossible because of diffraction in traditional optical microscopy ob-servation techniques. However, in recent years, it has been possible to observe microstructures beyond the Rayleigh criterion by analysing the phase distribution of light. This study investigated the physical reasons why phase analysis makes this new analysis technique possible using simula-tions. The results confirmed that the phase component of the zero-order diffracted light reflected from the microstructure and able to pass through the lens system contained the phase information related to the shape of the measured object. Analysis of this information demonstrates the possi-bility of realising super-resolution based on speckle interferometry.

We present three reduced integrable hierarchies of nonlocal integrable NLS type equations from a vector integrable hierarchy associated with a matrix Lie algebra, not being A type. Three similarity transformations are taken to keep the invariance of the transformed zero curvature equations. The key step is to formulate a solution to a reduced stationary zero curvature equation so that the zero curvature formulation works for a reduced case.

Thermoregulation is important for maintaining homeostasis of our body. It can be easily broken under anesthesia. An appropriate method to measure the core body temperature is needed, especially for elderly patients because the efficiency of thermoregulation gradually decreases with age. The aim of this study was to examine the accuracy and feasibility of using of SpotOn® sensor in lower extremity orthopedic surgery in elderly patients aged over 80 years by comparing a SpotOn® sensor with two other reliable minimal-invasive methods: a tympanic membrane thermometer and a bladder thermometer. This study enrolled 45 patients aged over 80 years who were scheduled to undergo a lower extremity surgery. Body temperature was measured using a SpotOn® sensor, tympanic membrane thermometer and bladder thermometer. Agreements between the SpotOn® sensor and the other two methods were assessed using Bland and Altman plots for repeated measures adjusted for unequal numbers of measurements per patient. Compared with TempBladder, bias and limits of agreement for TempZHF were 0.07℃ ± 0.58℃. Compared with TempTympanic, bias and limits of agreement for TempZHF were -0.28℃ ± 0.61℃. 3M SpotOn® sensor using ZHF method for patients aged over 80 years undergoing lower extremity surgery shows feasible measurement value and sensitivity.

This study reports an empirical analysis of an all-electric, Net Zero Energy Housing (NZEH) development located in a mixed-humid climate zone (4A, Virginia, USA). Circuit-level energy monitors were used to measure energy consumption and energy production data (solar photovoltaic) at 1-hr intervals in six identical apartments over 24 months. The study employs a multi-step case study methodology to a) empirically evaluate energy consumption and production data, b) identify the temporal variability of energy consumption and production data at different time scales, c) understand the impact(s) of weather and human-building interaction on energy consumption and production, and d) synthesize the study’s “lessons learned” toward data-driven recommendations for future NZEH researchers and practitioners. The study found that the development’s net zero energy goal was achieved in three of six case units and that NZEH housing performance was more influenced by human-building interaction than weather variability. The analysis also found the solar photovoltaic (PV) performance to be reliable across the sampled units over the periods of measurement, suggesting that solar PV could be oversized as an approach to overcome verifiability in HBI and achieve NZEH performance goals.

U-turns and left turns are sometimes forbidden even though it increases travel distances. The greater travel distances are sometimes outweighed by the improved movement through intersections due to there being fewer conflicting lanes of traffic. One can, further, forbid straight-throughs. Restricting a sufficient number of turns can make intersections free from crossing lanes of traffic (``zero traffic conflict,'' ``ZTC"), though there may still be merging lanes of traffic. It's possible to make \begin{it}all\end{it} intersections in a road \begin{it}network\end{it} ZTC. However, keeping all destinations accessible and travel distances moderate requires careful selection of allowed driving directions and turning directions. We demonstrate through numerical microscopic and macroscopic simulations that there are road networks and ranges of traffic loads for which, in comparison with conventional schemes, ZTC road network can carry approximately $50$\% more vehicular traffic without incurring gridlock.

This paper provides an open dataset of measured energy use, solar energy production, and building air leakage data from a 328 m² (3,531 ft²) all-electric, zero energy commercial building in Virginia, USA. Over two years of energy use data were collected at 1-hour intervals using circuit-level energy monitors. Over six years of solar energy production data were measured at 1-hour intervals by 56 microinverters. The building air leakage data was measured post-construction per ASTM-E779 Standard Test Method for Determining Air Leakage Rate by Fan Pressurization and the United States Army Corps (USACE) Building Enclosure Testing procedure; both pressurization and depressurization results are provided. The architectural and engineering (AE) documents are provided to aid researchers and practitioners in reliable modelling of building performance. The paper describes the data collection methods, cleaning, and convergence with weather data. This dataset can be employed to predict, benchmark, and calibrate operational outcomes in zero energy commercial buildings.

Controversial hypotheses to explain consciousness exist in many fields of science, psychology and philosophy. Recent experimental findings in quantum cognition and magnetic resonance imaging have added new controversies to the field, suggesting that the mind may be based on quantum computing. Quantum computers process information in quantum bits (qubits) using quantum gates. At a first glance, it seems unrealistic or impossible that the brain can meet the challenges to provide either of these. Nevertheless, we show here why the brain has the incredible ability to perform quantum computing and how that may be realized.

We present a discussion and analysis regarding the benefits and limitations of open and non-anonymized peer review based on literature results and responses to a survey on the reviewing process of alt.chi, a more or less open-review track within the CHI conference, the predominant conference in the field of human-computer interaction (HCI). This track currently is the only implementation of an open-peer-review process in the field of HCI while, with the recent increase in interest in open science practices, open review is now being considered and used in other fields. We collected 30 responses from alt.chi authors and reviewers and found that, while the benefits are quite clear and the system is generally well liked by alt.chi participants, they are reluctant to see it used in other venues. This concurs with a number of recent studies that suggest a divergence between support for a more open review process and its practical implementation. The data and scripts are available on https://osf.io/vuw7h/, and the figures and follow-up work on http://tiny.cc/OpenReviews.

The world is facing several global issues such as food and energy crisis, climate change and greenhouse gases emissions. To subdue these issues, many entities from academia and industries have innovated alternate techniques of performing regular activities which cause such problems. One of these innovations is the introduction of vertical and zero acreage farming in the field of sustainability. These carry the potential to solve one of the most important affairs of food security in most countries of the world. But, this technology has been in its nascent stage for many years. This paper uses a comprehensive framework proving the feasibility of initiating vertical farming on university campuses to feed the staff and students, which could also set an example to the rest of the world into using this technique on a wider scale. The study chose Huazhong University of science and technology (HUST) in Wuhan city, China for accessing the return on investment and food sufficiency if vertical farming is implemented. Using Central Limit Theorem, a statistical model was developed, and various scenarios were analyzed. The results indicated that if a separate vertical farm is constructed, the breakeven can be achieved in a range of 10-20 depending on parameters such as type of operation, number of floors and amount of vegetation. The study has shown that the use of vertical farming cannot only bring in revenue for the campus but also aid in mitigating climate change.

Hybrid reverse osmosis electrodialysis systems make it possible to obtain solutions with a higher concentration of components compared to single electrodialysis treatment, i.e. more efficient separation of brine and pure water. The article proposes experimental and pilot-industrial studies of a hybrid membrane system operation using industrial wastewater for the disposal of liquid waste from an ion-exchange chemical-desalting water treatment plant of a thermal power plant, followed by a calculation of economic efficiency and an analysis of the environmental feasibility of their use. The developed technological scheme offers separate processing of acidic and alkaline waste regeneration solutions using calcium carbonate reagent and desalination on baromembrane and electromembrane units to obtain clean water and dry residue. The hybrid system includes a booster filter press and an evaporator. The hybrid system makes it possible to provide a thermal power plant with a "zero discharge" with a minimum consumption of reagents and electricity, as well as return all water from wastewater to the power plant cycle.

Nepal, primarily an agricultural country, heavily relies on agricultural residue and fuelwood for daily energy requirements. In 2022, total energy consumption was 640 PJ, with traditional sources accounting for 64.17%, and fuelwood comprising 58.53% of total fuel consumption. The estimated potential supply of agricultural residue is 26 million tonnes, yielding about 442 million GJ of energy in 2021. Biomass trading often emphasizes volume or weight, necessitating a rapid and non-destructive assessment of energy properties for mutual benefit, aiding in the identification, management, and utilization of biomass sources. In this study, 200 biomass samples were collected in two batches (126 and 74 samples) from various locations in Nepal. Using Partial Least Squares Regression (PLSR), a model was developed correlating higher heating value (HHV) from a bomb calorimeter and spectral data from Fourier Transform near-infrared spectroscopy (FT-NIRS) (3595 – 12,489 cm-1) sensor. PLSR models incorporated raw spectra, eight preprocessing techniques, the multi-preprocessing five-range method, and a genetic algorithm. Outliers in the first batch were identified, and the first batch divided into an 80% calibration set and a 20% validation set, while the second batch was designated as an unknown sample set. The optimum PLSR model, utilizing first derivative preprocessing, improved accuracy by 6.77%, with coefficients of determination in the calibration set, validation set, and unknown set as 0.9694, 0.9578, and 0.8089, respectively. Root mean square errors were 132.4790 J/g, 189.4800 J/g, and 360.8845 J/g for the calibration set (RMSEC), validation set (RMSEP), and unknown set (RMSEUN), respectively. The prediction to deviation ratio (RPD) for the validation set and unknown set was 4.9 and 2.4, respectively. The cross validation model of combined sample data of every sets showed the R2CV of 0.95 and RPDCV of 4.6 indicating the model could serve as a reliable and swift non-destructive alternative for evaluating biomass HHV using NIRS and ready for updating for industrial use. However, incorporating a larger number of representative samples is crucial to enhance accuracy and develop a more comprehensive global model for predicting biomass HHV.

Directed energy deposition (DED) parameters were determined for near-β alloy Ti-55511 by employing statistical design of experiments (DOE) methods. Parameters resulting in fully dense freeform deposits were identified using two sequential DOEs. Single laser tracks were printed with several laser power, traverse rate, and powder feed rate settings in an initial DOE to identify promising build parameters. Capture efficiency and effective deposition rate were used to characterize and rank the single track deposits. The best parameters were then used to print solid cube with various X-Y and Z-overlaps (different hatch spacing, HS, and layer thickness, ZS) in a second DOE. Suitable deposition parameters were selected based on cube density and microstructure and were used to fabricate larger tensile samples for mechanical testing. Multiple parameter sets were found to provide dense Ti-55511 deposits with acceptable mechanical properties and parametric models showed statistical significance.

Fatal hemoptysis secondary to severe pulmonary veins stenosis is an exceptional late complication of radiofrequency ablation for atrial fibrillation. We report the case of a 53-year-old male with a history of atrial fibrillation treated by radiofrequency ablation and admitted in our center 6 months after the initial procedure because of aggravating dyspnea and fatigability. Transthoracic echocardiography showed moderate dilation of right heart cavities, severe pulmonary hypertension, and a turbulent flow in superior pulmonary veins. The cardiologist suspected pulmonary vein(s) stenosis and cardiac computed tomography (CT) angiography was performed with findings of severe stenosis of the right superior, right inferior and left inferior pulmonary veins, near-occlusion of the left superior pulmonary vein and the vein draining the apical segment of the right lower lobe. The CT scan also revealed soft tissue attenuation of the mediastinum posterior to the left atrium suggesting fibrosing mediastinitis together with parenchymal findings consistent with pulmonary venooclusive disease and an area of hemorrhagic infarction. Fatal hemoptysis occurred 3 days after the evaluation before any treatment was attempted. In conclusion, severe pulmonary stenosis remains a rare but severe complication of radiofrequency ablation. Prevention is the key element together with an early diagnosis as the entity is potentially life-threatening.

The flour milling industry, a vital component of global food production, is undergoing a transformative phase driven by the integration of smart devices and advanced technologies. This transition promises improved efficiency, quality, and sustainability in flour production. Accurate estimation of protein, moisture and ash content in wheat grains and flour is of paramount importance due to their direct impact on product quality and compliance with industry standards. This paper explores the application of Near-Infrared (NIR) spectroscopy as a non-destructive, efficient, and cost-effective method for measuring the aforementioned essential parameters in wheat and flour, by investigating the effectiveness of a low-cost handle NIR spectrometer. Furthermore, a novel approach using Fuzzy Cognitive Maps (FCMs) is proposed to estimate protein, moisture and ash content in grain seeds and flour, marking the first known application of FCMs in this context. Our study includes an experimental setup that assesses different types of wheat seeds and flour samples and evaluates three NIR pre-processing techniques to enhance parameter estimation accuracy. The results indicate that low-cost NIR equipment can contribute to the estimation of the under-study parameters.

Food safety and quality are the first steps in the food chain. This work reports a low-cost and easy-to-use optoelectronic measurement system for improving feed chain quality and safety, based on near-infrared spectrometry (NIRS) technology. This is a significant challenge for dairy farm technicians and producers who need rapid and reliable knowledge of forage quality on their farms. In most cases, instrumentation suitable for these specifications is expensive and difficult to operate. The core of the measurement system is Texas Instruments´ NIRscan Nano Evaluation Module (EVM) spectrometer. This module has a large sensing area and high resolution suitable for forage samples. To evaluate the feasibility of the prototype to analyze agrifood samples, different ways of presenting the sample, intact or ground, were tested. The final objective of the research is not just to check the efficiency of the proposed system. It is also to determine the measurement system characteristics and how to improve them.

Background: In recent years, the assessment and guidance of cardiopulmonary resuscitation (CPR) quality using noninvasive and invasive monitoring techniques have been increasingly recommended. In this study, we introduce a new physiological monitoring system that simultaneously measures arterial pressure (AP), venous pressure (VP), and cerebral tissue oxygen saturation (SctO2) during CPR. Methods: This prospective observational study was conducted at a single center (Kagoshima City Hospital). Adult out-of-hospital patients aged ≥18 years with an intravenous femoral arterial line, venous line, and SctO2 monitor were included. We measured femoral arterial pressure (FAP) and femoral venous pressure (FVP) invasively if catheters were immediately inserted into the femoral artery and vein for potential candidates who require interventions such as extracorporeal cardiopulmonary resuscitation but did not receive such interventions as a result. Results: We observed several representative cases that provided the following insights: We presented several cases, including two patients with significant increases in FVP and low SctO2 values, and in both cases, return of spontaneous circulation (ROSC) was not achieved. In contrast, we also presented two cases in which CPR resulted in higher FAP compared to FVP and an upward trend in SctO2 values was observed, and both instances achieved ROSC. Conclusion: We presented a simultaneous physiological monitoring system that can monitor AP, VP, and SctO2 during CPR. Further case accumulations will be necessary to assess the variations in hemodynamic status during CPR and the association between each hemodynamic status and outcomes after cardiac arrest.

Work done by us shows that rough topology is a good tool for dealing with things that happen in the real world. The concept of ”basis” has been used to show out the deciding elements of the recent outbreak of COVID-19 that was reported all over the world.

Hypoxic-ischemic encephalopathy (HIE) secondary to perinatal asphyxia occurs when the brain does not receive enough oxygen and blood. A surrogate marker for ‘intact survival’ is necessary for the successful management of HIE. The severity of HIE can be classified based on clinical presentation, including presence of seizures, using a clinical classification scale called Sarnat staging; however, Sarnat staging is subjective and the score changes over time. Furthermore, seizures are difficult to detect clinically and are associated with a poor prognosis. Therefore, a tool for continuous monitoring on the cot side is necessary, for example, electroencephalogram (EEG) that non-invasively measures the electrical activity of the brain from the scalp. Then, multimodal brain imaging, when combined with functional near-infrared spectroscopy (fNIRS), can capture the neurovascular coupling (NVC) status. In this study, we first tested the feasibility of a low-cost EEG-fNIRS imaging system to differentiate between normal, hypoxic, and ictal states in a perinatal ovine hypoxia model. Here, the objective was to evaluate a portable cot side device and autoregressive (ARX) modelling to capture the perinatal ovine brain states during a simulated HIE injury. So, ARX parameters were tested with a linear classifier using a single differential channel EEG, with varying states of tissue oxygenation detected using fNIRS, to label simulated HIE states in a perinatal ovine hypoxia model. Then, we showed the technical feasibility of the low-cost EEG-fNIRS device and ARX modeling with support vector machine classification for a human HIE case series with and without sepsis. The classifier trained with the ovine hypoxia data labelled ten severe HIE human cases (with and without sepsis) as “hypoxia” group and the four moderate HIE human cases as the “control” group. Furthermore, we showed the feasibility of experimental modal analysis (EMA) based on the ARX model to investigate the NVC dynamics using EEG-fNIRS joint-imaging data that differentiated six severe HIE human cases without sepsis from four severe HIE human cases with sepsis. In conclusion, our study showed the technical feasibility of EEG-fNIRS imaging, ARX modeling of NVC for HIE classification, and EMA that may provide a biomarker to detect sepsis effects on the NVC in HIE.

Diffuse optical tomography (DOT) is an optical medical imaging method that can assess the structural properties of tissues and their functional characteristics, such as hemoglobin concentration, water content, as well as lipid concentration, via three-dimensional image reconstruction. This paper presents the theoretical basis and working principle of diffuse optical tomography. The paper explains how the optical properties of tissue can be imaged by photon migration techniques based on diffusion theory. The author presents the reasoning for near-infrared (NIR) imaging as the most effective technique in terms of quantitative recovery of spectroscopic optical parameters. This work also listed various advantages, applications, and challenges of DOT. The paper also briefly discusses current progress in near-infrared medical imaging and its future direction.

Magnesium-silver alloys are of high interest for the use as temporary bone implants due to their antibacterial properties in addition to biocompatibility and biodegradability. Thin wires in particular can be used for scaffolding, but the determination of their degradation rate and homogeneity using traditional methods is difficult. Therefore, we have employed 3D imaging using X-ray near-field holotomography with sub-micrometer resolution to study the degradation of thin (250 μm diameter) Mg-2Ag and Mg-6Ag wires. The wires were studied in two states, recrystallized and solution annealed to assess the influence of Ag content and precipitates on the degradation. Imaging was employed after degradation in Dulbecco’s modified Eagle’s medium and 10% fetal bovine serum after 1 to 7 days. At 3 days of immersion the degradation rates of both alloys in both states were similar, but at 7 days higher silver content and solution annealing lead to decreased degradation rates. The opposite was observed for the pitting factor. Overall, the standard deviation of the determined parameters was high, owing to the relatively small field of view during imaging and high degradation inhomogeneity of the samples. Nevertheless, Mg-6Ag in the solution annealed state emerges as a potential material for thin wire manufacturing for implants.

Drought stress at the reproductive stage in rice is one of the most important cause for yield reduction, affecting both productivity and quality. All Basmati rice varieties, including the popular cultivar ‘Pusa Basmati 1 (PB1)’ is highly sensitive to reproductive stage drought stress (RSDS). We report for the first time, improvement of a Basmati cultivar for RSDS tolerance, with the introgression of a major quantitative trait locus (QTL), ‘qDTY1.1’ into PB1. The QTL donor was sourced from an aus variety, Nagina 22 (N22). A QTL linked microsatellite (SSR) marker ‘RM 431’ was employed for foreground selection for qDTY1.1 in the marker assisted backcross breeding process. A set of 113 SSR markers polymorphic between N22 and PB1 were utilized for background selection to ensure higher genome recovery. After three backcrosses followed by five generations of selfing, eighteen near isogenic lines (NILs) were developed, through combinatory selection for agro-morphological, grain and cooking superiority traits. The NILs were evaluated for three consecutive Kharif seasons, 2017, 2018 and 2019 under well-watered and drought stress conditions. RSDS tolerance and yield stability indicated that NIL3, NIL5, NIL6, NIL7, NIL12, NIL15 and NIL17 were best in terms of overall agronomic and grain quality under RSDS. Additionally, NILs exhibited high yield potential under normal condition as well. The RSDS tolerant Basmati NILs with high resilience to water stress, is a valuable resource for sustaining Basmati rice production under water limiting production environments.

High-frequency near-infrared diode laser provides high peak output, low heat accumulation, and efficient biostimulation. Although these characteristics are considered suitable for osteoarthritis (OA) treatment, the effect of high-frequency near-infrared diode laser in in vitro or in vivo OA models has not yet been reported. Therefore, we aimed to assess the biological effects of high-frequency near-infrared diode laser irradiation on IL-1β-induced chondrocyte inflammation in an in vitro OA model. Normal Human Articular Chondrocyte-Knee (NHAC-Kn) cells were stimulated with human recombinant IL-1β and irradiated with high-frequency near-infrared diode laser (910 nm, 4 or 8 J/cm2). The mRNA and protein expression of relevant inflammation- and cartilage destruction-related proteins was analyzed. IL-1β treatment significantly increased the mRNA levels of IL-1β, IL-6, TNF-α, MMP-1, MMP-3, and MMP-13. High-frequency near-infrared diode laser irradiation significantly reduced the IL-1β-induced expression of IL-1β, IL-6, TNF-α, MMP-1, and MMP-3. Similarly, high-frequency near-infrared diode laser irradiation decreased the IL-1β-induced increase in protein expression and secreted levels of MMP-1 and MMP-3. These results highlight the therapeutic potential of high-frequency near-infrared diode laser in OA.

Modeling and design of fiber lasers facilitate the process of their practical realization. Of particular interest during the last few years is the development of lanthanide ion-doped fiber lasers which operate at wavelengths exceeding 2000 nm. There are two main host glass materials considered for this purpose, namely fluoride and chalcogenide glasses. Therefore, this study concerns comparative modeling of fiber lasers operating within the infrared wavelength region beyond 2000 nm. In particular, the convergence properties of selected algorithms, implemented within various software environments, are studied with a specific focus on the central processing unit (CPU) time and calculation residual. Two representative fiber laser cavities are considered: one is based on a chalcogenide-selenide glass step-index fiber doped with trivalent dysprosium ions whilst the other is a fluoride step-index fiber doped with trivalent erbium ions. The practical calculation accuracy is also assessed by comparing directly the results obtained from the different models.

Owing to the growing concerns due to dwindling fossil fuel reserves, increasing energy demand and climate emergency, it is imperative to develop and deploy sustainable energy technologies to ensure future energy supply as well as transition to the net zero world. In this context, there is great potential in the biorefinery concept for supplying drop in biofuels in the form of biodiesel. Biodiesel as a fuel can certainly bridge the gap where electrification or the use of hydrogen is not feasible, for instance heavy vehicles, farm and marine transportation sector. However, biodiesel industry also leads to formation of large amount of crude glycerol as the byproduct. Crude glycerol due to presence of several impurities may not be a suitable feedstock for all high value products derived from glycerol but fits well with glycerol esterification for producing glycerol acetins, which have numerous applications. This review critically looks at the processes using nanostructured solid/liquid acid catalysts for glycerol esterification including the economic viability of the scale up.

The UK government and many international experts have pointed out that nuclear energy has an important role to play in the transition towards a decarbonized energy system since it is the only freely manageable very low-carbon energy technology with 24/7 availability to complement renewables. Besides current investments in light water reactor technologies, we need innovation for improved fuel usage and reduced waste creation, like offered by iMAGINE, for the required broad success of nuclear technologies. To allow quick progress into innovative technologies like iMAGINE and their regulation, a timely investment into urgently needed experimental infrastructure and expertise development will be required to assure the availability of capacities and capabilities. The initial steps to start the development of such a new reactor physics experimental facility to investigate molten salt fast reactor technology are discussed and a stepwise approach for the development of the experimental facility is described. The down selection to the choice for a diverse control and shutdown system is described through manipulating the reflector (control) and splitting the core (shutdown). The developed innovative core design of having the two core parts in two different rooms opens completely new opportunities and will allow to manifest the request for separated operational and experimental crews, as nowadays requested by regulators into the built environment. The proposed physical separation of safety relevant operational systems from the experimental room should on the one hand help to ease the access to the facility for visiting experimental specialists. On the other hand, the location of all safety relevant systems in a now separated access-controlled area for the operational team will limit the risk of misuse through third party access. The planned experimental programme described with the major steps: core criticality experiments, followed by experiments to determine the neutron flux, neutron spectrum, and power distribution as well as experiments to understand the effect of changes in reactivity and flux as a function of salt density, temperature and composition change.

Batch and transport experiments were used to investigate the remediation of a loamy sand soil contaminated with Cr(VI) using zero valent iron nanoparticles (nZVI) stabilized by the carboxy methyl cellulose (CMC-nZVI). The effect of pH, ionic strength (IS), and flow rate on the removal efficiency of Cr(VI) were investigated under equilibrium (uniform transport) and non-equilibrium (Two-site sorption) transport using the Hydrus-1D model. The overall removal efficiency ranged from 70 to over 90% based on the chemical characteristics of the CMC-nZVI suspension and the transport conditions. The concentration and pH of the CMC-nZVI suspension had the most significant effect on the removal efficiency and transport of Cr(VI) in the soil. The average removal efficiency of Cr(VI) was increased from 24.1 to 75.5% when the concentration of CMC-nZVI nanoparticles was increased from 10 to 250 mg L-1, mainly because of the increased total surface area at larger particle concentration. Batch experiments showed that removal efficiency of Cr(VI) was much larger under acidic conditions. The average removal efficiency of Cr(VI) reached 90.1 and 60.5 % at pH 5 and 7, respectively. The Two-site sorption model described quite well (r2 = 0.96-0.98) the transport of Cr(VI) in soil as compared to the uniform transport model (r2 = 0.81-0.98). The average retardation of Cr(VI) was 3.51 and 1.61 at pH 5 and 7, respectively, indicating earlier arrival for the breakthrough curves and shorter time to reach maximum relative concentration at lower pH. The Hydrus-1D model has proven to be an efficient tool for assessing the removal of Cr(VI) pollutants, offering innovative, cost-effective, and environmentally friendly remediation methodologies.

(1) Background: “Zero-dose” (ZD) refers to a child not receiving any doses of the pentavalent (diphtheria-tetanus-pertussis-Haemophilus influenzae type b (Hib)-Hepatitis B) vaccine in the routine national immunization schedule. These children are vulnerable to vaccine-preventable diseases (VPDs), and are often already disadvantaged due to poverty, conflict, and lack of access to basic health services. The Luambo health district (HD) is one of the 26 HDs in the Kasai Central Province and has the largest number of ZD children. This study was conducted to examine the factors associated with ZD status in the Luambo HD; (2) Methods: We conducted a mixed study of children aged 12-23 months in the Luambo HD in the Kasai Central Province; (3) Results: A total of 445 children aged 12-23 months were included in the study, including 89 cases and 356 controls. Correlates of zero dose (ZD) status in children aged 12-23 months were mothers who were not receiving Antenatal Care (ANC), of not knowing any VPD, the fact of the children being born in Angola and the fact of the children being born at home. In addition, the perceptions of children’s parents influenced child immunization; (4) Conclusions: Missing ANC services during pregnancy leads to home delivery with consequences being lack of knowledge on childhood’s VPD and subsequently children not being vaccinated.