REVIEW | doi:10.20944/preprints201809.0243.v1
Subject: Physical Sciences, Optics And Photonics Keywords: integrated optical sensors; monolithic integration; broad-band interferometers; label-free; multiplexed detection; on-site determinations
Online: 13 September 2018 (14:44:50 CEST)
The article reviews the current status of label-free integrated optical sensors focusing on the evolution over the years of their analytical performance. At first a short introduction to the evanescent wave optics is provided followed by detailed description of the main categories of label-free optical sensors including sensors based on surface plasmon resonance (SPR), grating coupler, photonic crystals, ring resonators and interferometric transducers. After a short reference to SPR techniques, including localized SPR, integrated optical sensors i.e., grating-couplers, interferometers, photonic crystals, microring resonators are reviewed. For each type of sensor, the detection principle is first provided followed by description of the different transducer configurations so far developed and their performance as biosensors. Finally, a short discussion about the current limitations and future perspectives of integrated label-free biosensors optical sensors is provided
REVIEW | doi:10.20944/preprints202306.2108.v1
Online: 29 June 2023 (11:18:08 CEST)
Optical immunosensors are one of the most popular category of immunosensors with applications in many fields including diagnostics, environmental and food analysis. The latter field is of particular interest not only for the scientists but also for the regulatory authorities and the public since food is essential for life but can be also the source of many health problems. In this context, the current review aims to provide an overview of the different types of optical immunosensors focusing onto their application for the determination of pathogenic bacteria in food samples. In particular, after the description of main optical transduction techniques, their implementation for the immunochemical determination of bacteria will be discussed. Finally, a short commentary about the future trends in optical immunosensors for food safety applications will be provided.