ARTICLE | doi:10.20944/preprints202209.0221.v1
Subject: Environmental And Earth Sciences, Oceanography Keywords: seagrass; remote sensing; machine learning; species distribution model (SDM); hybrid model; habitat suitability; niches; meta-heuristic optimization
Online: 15 September 2022 (07:32:27 CEST)
Globally, seagrass meadows provide critical ecosystem services. However, seagrasses are globally degraded at an accelerated rate. The lack of information on seagrass spatial distribution and seagrass health status seriously hinders seagrass conservation and management. Therefore, this study proposes to combine remote sensing big data with a new hybrid machine learning model (RF-SWOA) to predict potential seagrass habitats. The multivariate remote sensing data is used to train the machine learning model, which can improve the prediction accuracy of the model. This study shows that a hybrid machine learning model (RF-SWOA) can predict potential seagrass habitats more accurately and effectively than traditional models. At the same time, it has been shown that the most important factors influencing the potential habitat of seagrass in the Hainan region were the distance from land (38.2%) and the depth of the ocean (25.9%). This paper provides a more accurate machine learning model approach for predicting the distribution of marine species, which can help develop seagrass conservation strategies to restore healthy seagrass ecosystems.
REVIEW | doi:10.20944/preprints202105.0065.v1
Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: human papillomavirus; head and neck cancer; cancer subtypes; gene expression; oropharynx; HPV integration; immune response; keratinization
Online: 5 May 2021 (13:39:59 CEST)
Until recently, research on the molecular signatures of HPV-associated head and neck cancers mainly focused on their differences with respect to HPV-negative HNSCCs. However, given the continuing high incidence level of HPV-related HNSCC, the time is ripe to characterize the heterogeneity that exists within these cancers. Here, we review research thus far on HPV-positive HNSCC molecular subtypes, and their relationship with clinical characteristics and HPV integration into the host genome. Different omics data including host transcriptomics and epigenomics, as well as HPV characteristics, can provide complementary viewpoints. Keratinization, mesenchymal differentiation, immune signatures, stromal cells, and oxidoreductive processes all play important roles.
REVIEW | doi:10.20944/preprints201810.0012.v1
Subject: Medicine And Pharmacology, Other Keywords: noninvasive glucose measurement; IR spectroscopy; Raman spectroscopy; photoacoustic spectroscopy; microwave sensing
Online: 1 October 2018 (14:04:05 CEST)
Diabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful and costly which make noninvasive glucose sensors highly demanded. In this review paper, we discuss several advanced electromagnetic (EM) wave based technologies for noninvasive glucose measurement, including infrared (IR) spectroscopy, photoacoustic (PA) spectroscopy, Raman spectroscopy, fluorescence, optical coherent tomography (OCT) and microwave sensing. Development and progress of each method are discussed regarding fundamental principle, system setup and experimental results. Despite the promising achievements reported previously, there is no established product to obtain FDA approval or survive marketing test. Limitations and prospects of these techniques are discussed at the end of this review.
REVIEW | doi:10.20944/preprints202305.0300.v1
Subject: Chemistry And Materials Science, Biomaterials Keywords: Chitosan; Hydrogel; biomedical application; stimuli-responsive hydrogels; synthesis methods; characterization methods
Online: 5 May 2023 (04:50:52 CEST)
The prospective applications of chitosan-based hydrogels (CBHs), a category of biocompatible and biodegradable materials, in biomedical disciplines such as tissue engineering, wound healing, drug delivery, and biosensing have garnered great interest. The synthesis and characterization processes used to create CBHs play a significant role in determining their characteristics and effectiveness. The processing procedure could be tailored to obtain specific features like porosity, swelling, mechanical strength, degradation rate, and bioactivity, affecting the properties of CBHs to a great extent. Additionally, characterization methods aid in gaining access to the microstructures and properties of CBHs. Especially, this review provides a comprehensive assessment of the state-of-the-art with a focus on the affiliation between particular properties and application domains. The main obstacles and prospects for the future of CBH development for biomedical applications are also covered in the review.