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Preprint ARTICLE | doi:10.20944/preprints202303.0038.v1

The Lifetime Expenditure in People with Keratoconus in Saudi Arabia

Saleha K. Al-Atawi, Ali Alghamdi, Khaled Alzahrani

Subject: Medicine And Pharmacology, Ophthalmology Keywords: keratoconus; lifetime expenditure; economic burden; Keratoconus Economic Burden Questionnaire

Online: 2 March 2023 (08:48:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0762.v1

Burden of Care of Family Caregivers for People Diagnosed with Serious Mental Disorders in a Rural Health District in Kwa-Zulu-Natal, South Africa

Jabulile Thembelihle Ndlovu, Kebogile Elizabeth Mokwena

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Zarit Burden Interview scale; burden of care; home care giving; severe mental illness; rural setting

Online: 10 August 2023 (05:32:21 CEST)

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Jabulile Ndlovu1 and Kebogile Mokwena1, 2 1 Department of Public Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa 2 Research Chair in Substance abuse and population Mental Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa Corresponding author: jabulilendlovu5@gmail.com Abstract An estimated 6% of the world population has serious mental illness, with one in four families having a member with some form of psychiatric disorder, who are mostly cared for by their relatives within a family setting. Although caregiving in a home setting is reported to be associated with significant mental distress, the burden of such distress is rarely measured. The purpose of this study was to quantify the burden of care among family caregivers of relatives with serious mental disorders, as well as to explore possible association between the caregiver burden of care and a range of caregiver and Mental Health Care User (MHCU) variables in a rural district in Kwa-Zulu Natal, South Africa. The Zarit Burden Interview (ZBI) scale was used to collect data from 357 caregivers, and STATA 14 was used to analyze data. The ages of the sample ranged from 18 to 65, with a mean of 50.29, and the majority (86%) were female and unemployed (83%). The ZBI scores ranged from 8 to 85, with a mean of 41.59. The majority (91%) tested positive for caregiver burden of care, which ranged from mild to severe. Using the Pearson Chi-square test of association (p=0.05), variables that were significantly associated with the burden of care were clinically related (caregiver self-reported depression, MHCU diagnosis, recent relapse of the MHCU), socio-economic (caregiver family monthly income, MHCU disability grant status and MHCU employment status) and socio-demographic (MHCU gender and MHCU level of education). The prevalence of burden of care is high and severe, and scarcity of resources in families and communities contribute to the high burden of care in these rural communities.

Preprint ARTICLE | doi:10.20944/preprints202210.0094.v1

Estimating the Burden Among Informal Caregivers of Stroke Survivors in East Coast Peninsular Malaysia: A Short-Term Longitudinal Study

Mohd Azmi Bin Suliman, Xin Wee Chen, Mohd Ismail Ibrahim, Kamarul Imran Musa, Nurfaten Hamzah, Iliatha Papachristou Nadal, Feisul Idzwan Mustapha, Mohd Zulkifli Abdul Rahim, Norsima Nazifah Sidek, Jafri Malin Abdullah, Sureshkumar Kamalakannan

Subject: Public Health And Healthcare, Nursing Keywords: Stroke; informal caregiver; burden; Zarit Caregiver Burden Interview; Caregiver Assessment of Function and Upset; Malaysia

Online: 8 October 2022 (05:08:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0210.v1

Improving the Cognitive Impact of Migraine: A Real-World Study on the Ability to Concentrate

Isabel Pavão Martins, Beatriz Nunes Vicente, João Bajouco Nobre, Mariana Dias da Costa, Filipa Dourado Sotero

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: cognitive impact; chronic migraine; migraine burden

Online: 3 January 2024 (09:43:32 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202203.0014.v1

Body Plan Identity: A Mechanistic Model

James DiFrisco, Gunter Wagner

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: body plan; archetype; burden; generative entrenchment

Online: 1 March 2022 (10:17:43 CET)

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Preprint REVIEW | doi:10.20944/preprints202207.0315.v1

Protocol of the Dual Burden of Animal and Human Zoonoses: A Systematic Review

Liz P. Noguera Z., Duriya Charypkhan, Simon Rüegg, Sonja Hartnack, Paul Torgerson

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: protocol; review; zoonosis; zoonotic diseases; infectious diseases; burden of diseases; DALY; zDALY; monetary burden; animal losses

Online: 21 July 2022 (08:12:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.2025.v1

Effects of Premature Ventrıcular Complex Burden on Left Ventrıcular Global Longıtudınal Straın in Patıents Wıthout Structural Heart Dısease

Sukru Arslan, H. Ozan Arabaci, Muhammed Furkan Deniz, Mehmet Emin Gokce, Seyma Arslan, Veysel Oktay, Mustafa Yildiz, Isil Uzunhasan

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: idiopathic PVC; global longitudinal strain; PVC burden

Online: 29 January 2024 (13:05:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0861.v1

The Economic Burden of Alopecia Areata in Romania

Stefan Strilciuc, Rodica Olteanu, Rozalina Lăpădatu, Diana-Alecsandra Grad, Cristian Vlădescu, Alin Codruț Nicolescu

Subject: Medicine And Pharmacology, Dermatology Keywords: alopecia areata, cost of illness, economic burden

Online: 11 January 2024 (10:29:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0242.v1

Assessing Global Frailty Scores: Development of a Global Burden of Disease-Frailty Index (GBD-FI)

Mark O’Donovan, Duygu Sezgin, Zubair Kabir, Aaron Liew, Rónán O’Caoimh

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Frailty; Public Health; Global Burden of Disease

Online: 11 July 2020 (16:16:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0053.v1

Estimating the Burden of Serious Fungal Infections in Uruguay

Marina Macedo-Viñas, David W. Denning

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: epidemiology of fungal infections; infection burden; Uruguay

Online: 6 February 2018 (06:52:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1139.v1

How Possible Is the Elimination of Viral Hepatitis? An Analysis Based on the Global Burden of Disease from Hepatitis B and C, 1990–2019

Nelson Alvis-Guzman, Nelson J. Alvis-Zakzuk, Fernando De la Hoz Restrepo

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Hepatitis C; Elimination; Global Burden of Disease; Mortality

Online: 18 October 2023 (17:35:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0011.v1

Double Burden of Malnutrition (DBM) and Anaemia under the Same Roof: A Bangladesh Perspective

Sumaiya Mamun, Christopher Guy Nicholas Mascie-Taylor

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: double burden of malnutrition; anaemia; undernutrition; overweight; obesity

Online: 3 September 2018 (05:45:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201806.0392.v1

Amani Zidan, Ahmed Awaisu, Maguy El-Hajj, Samya Al-Abdulla, Dianne Figueroa, Nadir Kheir

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Medication-related burden; Questionnaire; chronic disease conditions; adherence

Online: 25 June 2018 (14:35:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0584.v1

Caregiver Burden in Small Animal Clinics: A Comparative Analysis of Dermatological and Oncological Cases

Pollyana T. R. F. Silva, Fernanda M. Coura, Adriane P. Costa-Val

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: burden of care; cat; dog; human-animal interaction; owner

Online: 8 December 2023 (10:25:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0035.v1

Effects of Meditation on Mental Health and Cardiovascular Balance in Caregivers

Lourdes Díaz-Rodríguez, Keyla Vargas-Román, Juan Carlos Sanchez-Garcia, Raquel Rodríguez-Blanque, Guillermo Arturo Cañadas- De la Fuente, Emilia I. De La Fuente-Solana

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: meditation; vagal nerve activity; high-burden caregivers; mental health.

Online: 1 December 2020 (15:11:39 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.0819.v1

Evaluate the Impact of the Long-Term Care Insurance (LTCI) System on Older Adults in Japan

Chuhan Miao, Beilei Li, Jianxun He

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Long-term care insurance; Japan; Older adults; Financial burden; Population

Online: 14 March 2024 (11:11:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.2007.v1

Τhe Cost and the Value of Stroke Care in Greece: Results from the SUN4P Study

Olga Ch. Siskou, Petros Galanis, Olympia Konstantakopoulou, Panagiotis Stafylas, Iliana Karagouni, Evangelos Tsampalas, Daphne Garefou, Helen Alexopoulou, Anasstasia Gamvroula, Maria Lypiridou, Ioannis Kalliotzakis, Anastasia Fragkoulaki, Aspasia Kouridaki, Argyro Tountopoulou, Ioanna Kouzi, Sofia Vassilopoulou, Efstathios Manios, Georgios Mavraganis, Anastasia Vemmou, Efstathia Karagkiozi, Christos Savopoulos, Grigorios George Dimas, Athina Myrou, Haralampos Milionis, Georgios Siopis, Xara Evaggelou, Athanase D. Protogerou, Stamatia Samara, Asteria Karapiperi, Nikolaos Kakaletsis, George Papastefanatos, Stefanos Papastefanatos, Panayota Sourtzi, George Ntaios, Konstantinos Vemmos, Eleni Korompoki, Daphne Kaitelidou

Subject: Public Health And Healthcare, Health Policy And Services Keywords: stroke; cost; burden; direct healthcare cost; loss of productivity; QALY

Online: 31 July 2023 (05:04:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1613.v1

Inhibition of Trichinella spiralis Membrane‐Associated Progesterone Receptor (MAPR) Results in the Reduction of Worm Burden

Muhammad Tahir Aleem, Zhaohai Wen, Zhengqing Yu, Cheng Chen, Mingmin Lu, Lixin Xu, Xiaokai Song, Xiangrui Li, Ruofeng Yan

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: inhibitory effect; knockdown; rTs‐MAPRC2‐Ab; Trichinella spiralis; worm burden

Online: 24 July 2023 (11:47:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0702.v1

The Burden of Air Pollution: A Perspective on Global Health Inequalities

Agnieszka Jakubowska

Subject: Environmental And Earth Sciences, Pollution Keywords: air pollution; disease burden; YLLs; YLDs; health inequalities; productivity loss

Online: 10 May 2023 (08:04:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.1273.v1

Quality of Life among Parents of Children and Adolescents with Diabetes: A Literature Review

Paraskevi Theofilou, Dimitrios Vlastos

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Diabetes; parents; children; adolescents; quality of life; stress; family burden

Online: 30 April 2023 (10:11:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0293.v1

Safety and Efficacy of Adjunctive Catheter-Directed Thrombolysis During Primary PCI for ST-segment Elevation Myocardial Infarction With High Thrombus Burden

Satsuki Noma, Hideki Miyachi, Isamu Fukuizumi, Junya Matsuda, Hideto Sangen, Yoshiaki Kubota, Yoichi Imori, Yoshiyuki Saiki, Yusuke Hosokawa, Shuhei Tara, Yukichi Tokita, Koichi Akutsu, Wataru Shimizu, Takeshi Yamamoto, Hitoshi Takano

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: high coronary thrombus burden; tissue plasminogen activator; catheter-directed thrombolysis

Online: 20 October 2021 (12:53:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0022.v1

90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil

Daniela Debone, Mariana da Costa, Simone Miraglia

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: COVID-19; Air pollution; Air quality; Health effects; Economic burden

Online: 2 August 2020 (11:59:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1541.v1

National Burden and Trends for 29 Groups of Cancer in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Saul A. Beltran-Ontiveros, Jose A. Contreras-Gutierrez, Erik Lizarraga-Verdugo, Erick P Gutierrez-Grijalva, Kenia Lopez-Lopez, Emilio H. Lora-Fierro, Miguel A. Trujillo-Rojas, Jose M. Moreno-Ortiz, Diana L. Cardoso-Angulo, Emir Leal-Leon, Jose R. Zatarain-Lopez, Hector M. Cuen-Diaz, Marisol Montoya-Moreno, Brisceyda Arce-Bojorquez, Jose L. Rochin-Teran, Daniel E. Cuen-Lazcano, Victor A. Contreras-Rodriguez, Ricardo Lascurain, Liliana Carmona-Aparicio, Elvia Coballase-Urrutia, Francisco Gallardo-Vera, Daniel Diaz

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Burden of disease; Cancer epidemiology; Cancer mortality, Malignant neoplasm; Public health

Online: 23 November 2023 (14:05:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1850.v1

Deepening Depression in Women Balancing Work-Life and Caregiving during the COVID-19 Pandemic: Findings of Gender-Specific Face-to-Face Street Interviews Conducted in Italy

Laura Giusti, Silvia Mammarella, Sasha Del Vecchio, Anna Salza, Massimo Casacchia, Rita Roncone

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Women; depression; family burden; family functioning; pandemic COVID-19; collective traumas

Online: 27 September 2023 (08:33:42 CEST)

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Purpose: This study investigated the impact of the COVID-19 pandemic on mental health, quality of life, and family functioning in a sample of the general female population, exploring difficulties encountered in managing family and work responsibilities and burden of care when taking care of a loved one. The study was moreover aimed at investigating factors capable of influencing severe depressive symptomatology in the context of socio-demographics, traumatic events, individual vulnerability, and family functioning. Method: During a weekend devoted to Mental Health initiatives (October 8-10, 2021), 211 women were interviewed (47% exposed to the 2009 L’Aquila earthquake). Results: More than 50% of the sample reported a higher complexity in managing their lives during the COVID-19 pandemic compared to their previous routine, with no statistically significant differences between working women and non-workers, although the latter obtained higher scores for depressive symptomatology and poorer quality of life. Compared to non-caregivers, women caregivers (22.3%) in charge of the care of loved ones affected by physical (10.9%) or psychiatric disabilities (11.4%) complained of a poorer quality of life, with those caring for people affected by mental disorders seeming to experience a more significant worsening. Approximately 20% of the total sample reported severe depressive symptomatology. Previous access to mental health services (O.R. 10.923), low level of education (O.R. 5.410) and difficulties in management of their everyday lives during the COVID-19 pandemic (O.R. 3.598) were found to be the main variables predictive of severe depressive psychopathology. Old age, good problem-solving skills and ability to pursue personal goals were identified as protective factors. Conclusions: The COVID-19 pandemic underlined the need for support for emotionally vulnerable women with pre-existing mental health conditions, partly reflecting the cumulative effects of traumas.

Preprint ARTICLE | doi:10.20944/preprints201909.0296.v1

BODE Index Correlated with Charlson Comorbidity Index and Medical Burden in COPD

Li Chin Ling, Lin Mei-Hsin, Tsai Yuh-Chyn, Chen Pei-Shiuan, Shen Lien-Shi, Kuo Ho-Chang, Liu Shih-Feng

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: chronic obstructive pulmonary disease; bode index; charlson comorbidity index; medical burden

Online: 26 September 2019 (09:58:37 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1863.v1

Long-Term Outcomes and Prognosis of Patients with Myocardial Infarction During Covid Pandemic

Marius Rus, Adriana Ioana Ardelean, Ana Maria Jurcau, Felicia Liana Andronie-Cioara, Paula Marian, Oana Lilliana Pobirci, Veronica Huplea, Alina Stanca Osiceanu, Adrian Gheorghe Osiceanu, Simina Crisan, Georgiana Carmen Filimon

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: COVID 19; myocardial infarction; cardiovascular burden; long-term outcomes; acute coronary syndrome

Online: 27 September 2023 (11:29:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0123.v1

The Prevalence of Periodontal Diseases in Portugal and Correspondent Digital National Awareness: Analysis of Data from Global Burden of Disease, Directorate-General of Health and Google Trends for the Period 2004-2017

Vanessa Machado, João Botelho, João Albernaz Neves, Luís Proença, Ricardo Alves, Maria Alzira Cavacas, João Rua, Ana Delgado, José João Mendes

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Medical Illiteracy, Public Awareness, Periodontal Diseases, Global Burden of Disease, Google Trends

Online: 13 February 2019 (15:54:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0030.v2

Using the Job Burden-Capital Model of Occupational Stress to Predict Depression and Well-Being among Electronic Manufacturing Service Employees in China

Chao Wang, Shuang Li, Tao Li, Shanfa Yu, Junming Dai, Xiaoman Liu, Xiaojun Zhu, Yuqing Ji, Jin Wang

Subject: Social Sciences, Psychology Keywords: occupational stress; job burden-capital model; structural equation model; depression; well-being

Online: 4 August 2016 (12:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0830.v2

The Economic Burden of Atopic Dermatitis in Romania: A Broad Perspective

Alin Codrut Nicolescu, Stefan Strilciuc, Rozalina Lapadatu, Diana Alecsandra Grad, Cristian Vladescu, Rodica Olteanu

Subject: Medicine And Pharmacology, Dermatology Keywords: Atopic dermatitis, economic burden of disease, cost of illness

Online: 16 January 2024 (10:29:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1343.v1

Depressive Disorders and EU Labour Resources – the Problem of Lost Productivity in Highly Developed Economies

Agnieszka Jakubowska

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: indirect costs of depression; burden of disease; lost productivity; inequality in the EU

Online: 18 December 2023 (15:14:46 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202103.0113.v1

Viewpoint: The Current Advances and Future Optimization of Blood-based Tumor Mutation Burden as a Biomarker for Cancer Immunotherapy

Anlin Li

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: blood-based mutation burden (bTMB); cancer immunotherapy; immune checkpoint inhibitor (ICI); biomarker; mutation

Online: 2 March 2021 (21:45:40 CET)

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Preprint REVIEW | doi:10.20944/preprints202101.0184.v1

Multi-pathogen Infections and Alzheimer’s Disease

Jiri Damborsky, Dana Vigasova, Michal Nemergut, Barbora Liskova

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Alzheimer’s Disease; antibacterial; anti-biofilm; antifungal; antiviral; bacteria; infectious burden; parasites; pathogens; viruses

Online: 11 January 2021 (11:28:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201901.0060.v1

Global Need for Physical Rehabilitation: Systematic Analysis from the Global Burden of Disease Study 2017

Tiago S. Jesus, Michel D. Landry, Helen Hoenig

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: rehabilitation; global health; disability; global burden of disease; health services needs and demand

Online: 8 January 2019 (10:52:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.2199.v1

Hope Mediates Stress to Reduce Burden in Family Caregivers of Persons with Dementia

Jocelyn Shealy McGee, Edward C. Polson, Dennis Myers, Angela McClellan, Rebecca Meraz, Weiming Ke, Holly Carlson Zhao

Subject: Public Health And Healthcare, Other Keywords: Alzheimer's disease; dementia; cargiving; burden; hope; positive psychology; positive aspects of caregiving; stress; coping

Online: 28 December 2023 (14:36:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.1395.v1

Sex, Age, and Regional Disparities in the Burden of Asthma in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Ana Lopez-Bago, Ricardo Lascurain, Pavel E. Hernandez-Carreño, Francisco Gallardo-Vera, Jesus Argueta-Donohue, Francisco Jimenez-Trejo, David A. Fuentes-Zavaleta, Saul A. Beltran-Ontiveros, Delia M. Becerril-Camacho, Victor A. Contreras-Rodriguez, Daniel Diaz

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Allergic diseases; Atopic march; Burden of disease; Chronic respiratory diseases; DALYs; Epidemiology; Incidence; Prevalence

Online: 21 June 2023 (08:52:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0084.v1

Incidence, Mortality, Disability-Adjusted Life Years, and Trends of Prostate Cancer in Mexico from 2000 to 2019: Results from the Global Burden of Disease Study 2019

Saul A. Beltran-Ontiveros, Martha A. Fernandez-Galindo, Jose M. Moreno-Ortiz, Jose A. Contreras-Gutierrez, Jesus Madueña-Molina, Elyakim Arambula-Meraz, Emir Leal-Leon, Delia M. Becerril-Camacho, Veronica J. Picos-Cardenas, Carla Angulo-Rojo, Diana Z. Velazquez, Francisco Jimenez-Trejo, Francisco Gallardo-Vera, Daniel Diaz

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Age-standardized rate; Burden of disease; Cancer epidemiology; Malign neoplasm; Sociodemographic index; Subnational heterogeneity

Online: 6 May 2022 (14:47:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0004.v1

N1-Methyladenosine (m1A) Regulator-Mediated Methylation Modification Modes and Tumor Microenvironment Infiltration Characteristics in Head and Neck Squamous Cell Carcinomas

Yan-Dong Miao, Lin-Jie Mu, Xiao-Long Tang, Jiang-Tao Wang, Jing-Jing Wu, Yong-Gang Chen, Deng-Hai Mi

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: m1A; Tumor microenvironment; PD-1/PD-L1; CTLA-4; Tumor Mutation Burden; Bioinformatics Analysis

Online: 1 November 2021 (10:39:51 CET)

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Preprint REVIEW | doi:10.20944/preprints202305.1239.v1

Immune Checkpoint Blockade and Biomarkers of Response in Lymphoma: A Case-Illustrated Narrative Review

Sarah Perdikis-Prati, Semira Sheikh, Bouroumeau Antonin, Noémie Lang

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Hodgkin lymphoma; non-Hodgkin lymphoma; PD1 / PD-L1 checkpoint inhibitors; tumor mutational burden; predictive biomarkers

Online: 17 May 2023 (10:52:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0590.v1

Estimates of Cancer Mortality Attributable to Carcinogenic Infections in Italy

Pietro Ferrara, Sara Conti, Fernando Agüero, Luciana Albano, Cristina Masuet-Aumatell, Josep Maria Ramon-Torrell, Lorenzo Giovanni Mantovani

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: burden of cancer mortality; cancer epidemiology; cancer etiology; cancer prevention; carcinogenic infections; modifiable risk factors

Online: 28 October 2020 (12:13:01 CET)

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Preprint REVIEW | doi:10.20944/preprints202007.0389.v1

Demanding of Lassa Fever: Reducing its Risk as an Infectious Disease

Abdullahi Tunde Aborode, Victor Adegbile Adesewa, Oni Ebenezer Ayomide, Samuel Ogunsola Olarenwaju

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Lassa Fever; Virus; Infectious Disease; Hazard; West Africa; Health Care; Epidemiology; Epidemic; Measures; Burden; Management

Online: 17 July 2020 (15:19:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0024.v1

The Critical Issues for Patients and Caregivers in Neuro-Oncology During Covid-19 Pandemic: What We Have Learnt by an Observational Study.

Elena Anghileri, Irene Tramacere, Sara Morlino, Catia Leuzzi, Lorena Pereja Gutierrez, Saba Motta, Antonio Silvani, Francesca Romana Berrini

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Anxiety; Caregivers; Caregiver Burden; Communication; COVID-19; (Brain) Neoplasms; Pandemics; Perception; Psycho-Oncology; Quality of Life

Online: 1 April 2024 (10:08:02 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202007.0633.v1

Community-Based Household Survey to Identify Disability Burden and Health-Related Quality of Life Following Road Traffic Accidents in Ujjain, India

Aditya Mathur, Love Mehra, Ashish Pathak

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Children; adolescents; post-road traffic accidents; EQ-5D-5L; disability burden; health-related quality of life

Online: 26 July 2020 (03:11:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0694.v1

Caregivers’ burden experience: a comparison between Parkinson's Disease, Multiple System Atrophy and Amyotrophic Lateral Sclerosis

Luna Carpinelli, Giulia Savarese, Claudio Russo, Giovanna Stornaiuolo, Ettore Luisi, Francesca Pellegrino, Monica Mollo, Antonella Toriello, Paolo Barone, Maria Teresa Pellecchia

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Caregivers’ burden; Quality of Life; Neurological diseases; Parkinson’ s Disease; Multiple System Atrophy; Amyotrophic Lateral Sclerosis

Online: 12 February 2024 (13:28:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0218.v1

Global Incidence and Mortality Patterns and Forecast of Pedestrian Road Traffic Injuries by Socio-Demographic Index Findings from the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study

Moien A. B. Khan, Michal Grivna, Javaid Nauman, Elpidoforos S. Soteriades, Arif Alper Cevik, Muhammad Jawad Hashim, Romona Govender, Salma Rashid Al Azeezi

Subject: Medicine And Pharmacology, Other Keywords: road traffic injuries; public safety; global burden; economic loss; health policy; health care system; health indicators; injury prevention

Online: 16 February 2020 (13:48:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0545.v1

Accurate and Efficient Explicit Approximations of the Colebrook Flow Friction Equation Based on Wright-Omega Function

Dejan Brkić, Pavel Praks

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Colebrook equation; hydraulic resistance; Lambert W-function; Wright Ω-function; explicit approximations; computational burden; turbulent flow; friction factor

Online: 23 October 2018 (16:28:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0187.v1

One-Log Call Iterative Solution of the Colebrook Equation for Flow Friction Based on Padé Polynomials

Pavel Praks, Dejan Brkić

Subject: Engineering, Control And Systems Engineering Keywords: Colebrook equation; Colebrook-White; flow friction; iterative procedure; logarithms; Padé polynomials; hydraulic resistances; turbulent flow; pipes; computational burden

Online: 11 July 2018 (03:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0123.v1

Active Case Finding for Tuberculosis through TOUCH Agents in Selected High TB Burden Wards of Kolkata, India: A Mixed-methods Study on Outcomes and Implementation Challenges

Abhijit Dey, Pruthu Thekkur, Ayan Ghosh, Tanusree Dasgupta, Soumyajyoti Bandopadhyay, Arista Lahiri, Chidananda SV, Milan Dinda, Vivek Sharma, Namita Dimari, Dibyendu Chatterjee, Isita Roy, Anuradha Chanda, Parthiban Shanmugam, Brojokishore Saha, Sanghamitra Ghosh, Sharath Nagaraja

Subject: Medicine And Pharmacology, Tropical Medicine Keywords: Active case findings; Tuberculosis; TOUCH Agent; High TB burden area; TB Surveillance; 4S Screening; THALI Project; SORT IT; Operational Research

Online: 11 September 2019 (13:30:30 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0361.v1

On Burden of Diseases, Prevention, Medical Research and Health Service Delivery: Grampian Case Study

Seshadri Vasan, Nicholas Fluck

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: burden of disease; disability-adjusted life year (DALY); disease prevention; epidemiology; health policy; health service; health surveillance; medical research; public health

Online: 6 December 2023 (08:07:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202105.0549.v1

What Could Explain the Lower COVID-19 Burden in Africa Despite Considerable Circulation of the SARS-CoV-2 Virus?

Richard G. Wamai, Jason L. Hirsch, Wim Van Damme, David Alnwick, Robert C. Bailey, Stephen Hodgins, Uzma Alam, Mamka Anyona

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19 pandemic; Africa; SARS-CoV-2 virus spread; lower COVID-19 disease burden; African populations; demographic pyramid; trained immunity; government measures

Online: 24 May 2021 (09:56:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0189.v1

The Global Burden of Type 2 Diabetes Attributable to Dietary Risks: Insights from the Global Burden of Disease Study 2019

Alina Ioana Forray, Mădălina Adina Coman, Ruxandra Simonescu-Colan, Andreea Isabela Mazga, Răzvan Mircea Cherecheș, Cristina Maria Borzan

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: type 2 diabetes mellitus; Global Burden of Disease Study; dietary risk factors; Age- Standardized Mortality Rate; Age-Standardized DALY Rate; Socio-Demographic Index

Online: 4 October 2023 (04:55:59 CEST)

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Preprint INTERESTING IMAGES | doi:10.20944/preprints202301.0439.v1

Low Health Literacy (LHL): A Devious Enemy of Patient Treatment Adherence

Abdul Kader Mohiuddin

Subject: Social Sciences, Psychology Keywords: parental health literacy; necessary health education; understanding treatment guidelines; medication non-adherence; healthcare; avoidable medical costs; global health burden; COVID-19 vaccine negligence

Online: 25 January 2023 (03:43:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0237.v2

Toward Evaluation of The Subjective Experience of A General Class of User-Controlled, Robot-Mediated Rehabilitation Technologies for Children with Neuromotor Disability

Manon Maitland Schladen, Kevin Cleary, Yiannis Koumpouros, Reza Monfaredi, Tyler Salvador, Hadi Fooladi Talari, Jacob Slagle, Catherine Coley, Staci Kovelman, Justine Belschner, Sarah Helen Evans

Subject: Social Sciences, Behavior Sciences Keywords: Game-based therapy; robot-mediated therapy; neuromotor disability; cerebral palsy; subjective assessment; patient-centered assessment; caregiver burden; ankle range of motion; ankle strengthening; home exercise program

Online: 12 October 2020 (10:09:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202209.0139.v1

BCG Vaccine – The Road Not Taken

Coad Dow, Laith Kidess

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Bacillus Calmette-Guérin (BCG); tuberculosis; Non-tuberculous mycobacteria (NTM); nonspecific effects; Trained Immunity; Type 1 Diabetes; Multiple Sclerosis; Parkinson’s Disease; Alzheimer’s disease; Mycobacterium avium ss. paratuberculosis (MAP); molecular mimicry; Global Burden of Disease

Online: 12 September 2022 (09:36:16 CEST)

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