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Preprint ARTICLE | doi:10.20944/preprints202310.0836.v1

Therapeutic Efficacy and Safety of Lenvatinib after Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma

Shigeki Yano, Tomokazu Kawaoka, Shintaro Yamasaki, Yusuke Johira, Masanari Kosaka, Yuki Shirane, Ryoichi Miura, Kei Amioka, Kensuke Naruto, Kenji Yamaoka, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Daiki Miki, Masataka Tsuge, Yuji Teraoka, Hirotaka Kouno, Shintaro Takaki, Nami Mori, Keiji Tsuji, Shiro Oka

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: hepatocellular carcinoma; unresectable; atezolizumab plus bevacizumab; lenvatinib

Online: 12 October 2023 (15:36:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0593.v1

Effectiveness of Atezolizumab in Metastatic Large Cell Neuroendocrine Carcinoma of the Lung and the Predictive Value of miR-375. The LANCE Trial, a Pilot Study

Georgios Evangelou, Ioannis P. Trontzas, Ioannis Gkiozos, Ioannis Vamvakaris, Maria Grammoustianou, Christina Paraskeva, Georgia Gomatou, Ioannis Tsamis, Ioannis A. Vathiotis, Maximilian Anagnostakis, Vasiliki Koliaraki, Konstantinos Syrigos

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: large cell neuroendocrine carcinoma; LCNEC; immunotherapy; atezolizumab; miR375

Online: 11 March 2024 (17:49:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.1767.v1

Usefulness of Tumor Marker Score for Prediction of Prognosis in Hepatocellular Carcinoma Patients Treated with Atezolizumab plus Bevacizumab: A Multicenter Retrospective Study

Kazunari Tanaka, Kunihiko Tsuji, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Atsushi Naganuma, Hisashi Kosaka, Tomomitsu Matono, Hidekatsu Kuroda, Yutaka Yata, Hideko Ohama, Fujimasa Tada, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Keisuke Yokohama, Hiroki Nishikawa, Michitaka Imai, Yohei Koizumi, Shinichiro Nakamura, Hiroko Iijima, Masaki Kaibori, Yoichi Hiasa, Takashi Kumada

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: hepatocellular carcinoma; tumor marker; atezolizumab plus bevacizumab; prognosis; predictive model

Online: 26 June 2023 (09:42:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1474.v1

Comparative Analysis of Atezolizumab Plus Bevacizumab and Hepatic Artery Infusion Chemotherapy in Unresectable Hepatocellular Carcinoma: A Multicenter, Propensity Score Study

Ji Hoon Kim, Hee-Chul Nam, Chang Wook Kim, Hee Sun Cho, Jae-Sung Yoo, Ji Won Han, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon, Hyun Yang, Si Hyun Bae, Suho Kim, Jung-Suk Oh, Ho Jong Chun, Chang Ho Chun, Jaegyoon Ahn, Pil Soo Sung

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Hepatocellular carcinoma; Atezolizumab–bevacizumab; Hepatic artery infusion chemotherapy; Overall survival; Progression-free survival

Online: 21 July 2023 (14:00:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1682.v1

Atezolizumab plus Bevacizumab Treatment Worsens Liver Reserve in Patients with Nafld/Nash-Associated Liver Cancer More than in Those with Non-nafld/Non-Nash-Associated Liver Cancer

Rie Sugimoto, Kenta Motomura, Takeaki Satoh, Yuki Tanaka, Shinsaku Yamashita, Nobito Higuchi, Toshimasa Koyanagi, Tsukasa Nakamura, Masatake Tanaka, Yuuki Azuma, Takeshi Goya, Akifumi Kuwano, Aritsune Ooho, Mari Ooe, Taiji Mutsuki, Masami Kuniyoshi, Kazuki Kurosaka, Yusuke Morita, Seiya Tada, Yoshifusa Aratake, Tsuyoshi Yoshimoto, Takeshi Senju, Tomoyuki Kurashige, Shigeru Harada, Akihiro Ueda, Masayuki Miyazaki, Makoto Nakamuta, Motoyuki Kohjima

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Atezolizumab; bevacizumab; non-alcoholic fatty liver disease; non-alcoholic steato hepatitis; albumin-bilirubin (ALBI) score

Online: 26 October 2023 (09:01:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0447.v1

Sex-based Clinical Outcome in Advanced NSCLC Patients Undergoing PD-1/PD-L1 Inhibitor Therapy - a Retrospective Bi-Centric Cohort Study

David Lang, Anna Brauner, Florian Huemer, Gabriel Rinnerthaler, Andreas Horner, Romana Wass, Elmar Brehm, Bernhard Kaiser, Richard Greil, Bernd Lamprecht

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Immunotherapy; immune-checkpoint inhibitor; response prediction; men and women; pembrolizumab; nivolumab; atezolizumab; ECOG; CRP; chemo-immunotherapy

Online: 24 November 2021 (09:02:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202105.0546.v1

Atezolizumab and Pembrolizumab in Triple-Negative Breast Cancer: A Meta-Analysis

Mahwish Amin, Shaiza Sharif, Waleed Asghar, Humaira Sadaf, Azza Sarfraz, Zouina Sarfraz, Ivan Cherrez-Ojeda

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: triple negative breast cancer; Pembrolizumab; Atezolizumab; chemotherapy; anti-PD-L1; biomarkers; targeted therapies; development of novel drugs

Online: 24 May 2021 (09:23:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0307.v3

Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials

Antonino Grassadonia, Isabella Sperduti, Patrizia Vici, Laura Iezzi, Davide Brocco, Teresa Gamucci, Laura Pizzuti, Marcello Maugeri-Saccà, Paolo Marchetti, Gaetana Cognetti, Michele De Tursi, Clara Natoli, Maddalena Barba, Nicola Tinari

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Immune Checkpoint Inhibitors; anti-PD-1/PDL-1; anti-CTLA-4; gender; sex; Nivolumab; Pembrolizumab; Atezolizumab; Ipilimumab; Durvalumab

Online: 15 November 2018 (07:02:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202103.0777.v1

Prediction of Response to Atezolizumab Plus Nab-Paclitaxel in Unresectable Locally Advanced Triple Negative Breast Cancer (TNBC): the ClinicalUsefulness of PD-L1 mRNA Expression in Plasma-Derived Exosomes

Lucrezia Raimondi, Gian Paolo Spinelli, Paolo Ciracì, Filippo Maria Raimondi, Rachele Lazzeroni, Laura Di Benedetto, Stefano Valabrega, Laura Giaconi, Luigi Rossi, Giuseppe Naso

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Exosomal PD-L1 mRNA; extracellular vesicles; Triple Negative Breast Cancer; Immunotherapy; PD-L1 axis; Atezolizumab – nab-paclitaxel; Predictive biomarkers; Liquid biopsy

Online: 31 March 2021 (15:27:45 CEST)

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