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Preprint ARTICLE | doi:10.20944/preprints201709.0016.v1

Responses of Soil Microbial Communities to Robinia Pseudoacacia Plantations of Different Ages in A Loess Area

Bingxue Zhang, Rumeng Zhao, Boyuan Bi, Fengpeng Han

Subject: Biology And Life Sciences, Forestry Keywords: soil; Robinia pseudoacacia; PLFA; stand age; microbial community

Online: 5 September 2017 (15:28:05 CEST)

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Phospholipid fatty acids (PLFAs) can be used as biomarkers for qualitative and quantitative analyses of soil microbial community diversity. In this study, we collected soil samples at 10-cm intervals to a depth of 1 m from Robinia pseudoacacia plantations of four different ages (10, 15, 25 and 40 years) in a loess area and analysed the soil microbial community structure by PLFA analysis. A total of 97 PLFAs were detected in soils of R. pseudoacacia plantations of different ages. The individual PLFA contents gradually decreased in the 0- to 40-cm soil layers, with little variation in the 40- to 100-cm soil layers. The individual PLFAs were similarly distributed in the soils of R. pseudoacacia plantations of different ages, and there was a clear variation with stand age and soil depth. The individual PLFA contents in the 0- to 20-cm soil layers were highest for the 25-year-old plantation, while those in the 20- to 40-cm soil layers were relatively high for the 25- and 40-year-old plantations; the 16:0 content was the highest among individual PLFAs. The total PLFA content and the PLFA contents of different microbial groups [bacteria, fungi, Gram-positive bacteria (G⁺), Gram-negative bacteria (G^-) and actinomycetes] initially increased before decreasing in the soils of R. pseudoacacia plantations with increasing stand age, whereas these contents gradually decreased with increasing soil depth; the highest PLFA contents was found in the 25-year-old plantation. The total PLFA content and the contents of fungal, G^- and actinomycete PLFAs in the soils of R. pseudoacacia plantations differed significantly among stands of different ages in the 0- to 10-cm, 10- to 20-cm and 30- to 40-cm soil layers, while no significant differences were found in the 20- to 30-cm soil layers; the G⁺ and bacterial PLFAs contents in each of the 0- to 40-cm soil layers were significantly different. The PLFA ratios between different microbial groups differed among the stands of different ages. The fungi/bacteria ratio showed a “decrease-increase-decrease” trend with stand age, while the G⁺/G^- ratio showed an “increase-decrease” trend. The saturated/monounsaturated PLFA ratio initially decreased before plateauing, while the opposite trend was observed for the cyclopropyl/precursor ratio. The PLFA contents of different microbial groups were ranked as follows: bacteria > G^- > G⁺ > actinomycetes > fungi. In the principle component analysis, 18:1ω9c, 10Me18:0, i17:0, a17:0, 18:1ω7c, 18:1ω5c and 18:0 made the greatest contribution to principal component 1, and a14:0, i14:0 3OH, i14:0, i14:1ω7c and 14:0 made the greatest contribution to principal component 2. In conclusion, soil nutrient status and other soil eco-environmental stress factors should be considered in 10- to 25-year-old (particularly ~15-year-old) plots for the management of R. pseudoacacia plantations to prevent forest soil degradation and improve forest stand quality, thereby achieving better soil and water conservation and environmental improvement in R. pseudoacacia plantations.

Preprint ARTICLE | doi:10.20944/preprints202312.0652.v1

Tritordeum Bulel and Aucan: Promising Cultivars to Improve Health

Salvatore De Caro, Antonella Venezia, Luigia Di Stasio, Donatella Danzi, Domenico Pignone, Gianfranco Mamone, Giuseppe Iacomino

Subject: Biology And Life Sciences, Life Sciences Keywords: cereal; protein-digested samples; gluten-related disorders; proteomics; tritordeum.

Online: 11 December 2023 (10:22:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0138.v1

Global Analysis of the WOX Transcription Factor Family in Akebia trifoliata

Shengpeng Chen, Huai Yang, Yongle Zhang, Chen Chen, Tianheng Ren, Feiquan Tan, Peigao Luo

Subject: Biology And Life Sciences, Plant Sciences Keywords: Akebia trifoliata; WUSCHEL-related homeobox; transcription factor; adventitious roots.

Online: 2 November 2023 (09:11:33 CET)

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Preprint REVIEW | doi:10.20944/preprints202305.1761.v1

Checkpoint Inhibitors Induced Colitis: From Pathogenesis to Management

Maria Terrin, Giulia Migliorisi, Arianna Dal Buono, Roberto Gabbiadini, Elisabetta Mastrorocco, Alessandro Quadarella, Alessandro Repici, Armando Santoro, Alessandro Armuzzi

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: checkpoint inhibitors; colitis; immune-related adverse events; enterocolitis; diarrhea

Online: 25 May 2023 (08:03:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0351.v1

Almamy Amara Touré, Aboubacar Sidiki Magassouba, Gnoume Camara, Abdoulaye Doumbouya, Diao Cissé, Ibrahima Barry, Lansana Mady Camara, Abdoul Habib Béavogui, Alexandre Delamou, Vanessa Veronese, Corinne Simone Merle, Hugues Asken Traoré, Adama Marie Bangoura

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: Tuberculosis; Health-related quality of life; COVID-19; Guinea

Online: 25 July 2022 (05:37:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0389.v1

Dynamics of Gut Microbiome and Transcriptome in Korea Native Ricefish (Oryzias latipes) during Chronic Antibiotics Exposure

Ju Bin Yoon, Sungmin Hwang, Jun Hyeok Yang, Seungki Lee, Woo Young Bang, Ki Hwan Moon

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Ricefish; Microbiome; Ampicillin; Erythromycin; Immune and Stress-Related Genes

Online: 29 June 2022 (03:05:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202108.0528.v1

The Effects of Intermittent Fasting on Brain and Cognitive Function

Jip Gudden, Alejandro Arias Vasquez, Mirjam Bloemendaal

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Intermittent fasting; cognition; brain-related diseases; prevention and progress

Online: 27 August 2021 (16:22:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0068.v1

Strategy Development of Information Technology–Related Services Using Tows Matrix Analysis: A Case of Neust San Isidro Campus

Emmanuel C. Navarro, Jennilyn C. Mina, Romeo B. Campos, Jr.

Subject: Business, Economics And Management, Accounting And Taxation Keywords: IT related services; strategy development; SWOT; TOWS Matrix Analysis

Online: 2 December 2020 (15:25:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints201906.0122.v1

Attention Modulates Electrophysiological Responses to Simultaneous Music and Language Syntax Processing

Daniel J Lee, Harim Jung, Psyche Loui

Subject: Social Sciences, Cognitive Science Keywords: music; language; syntax; attention; comprehension; electroencephalography; event-related potentials

Online: 13 June 2019 (13:13:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints201612.0132.v1

What Do We Know Now about IgE-Mediated Wheat Allergy in Children?

Grażyna Czaja-Bulsa, Michał Bulsa

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: wheat allergy; specific immunoglobulin E; children; gluten-related disorders

Online: 28 December 2016 (10:37:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1085.v1

Preparation and hydration properties of sodium silicate-activated municipal solid waste incineration bottom ash composite slag cementitious materials

Juan Deng, Guoxiong Wu, Yuchao Xia, Li Liu

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: MSWIBA, sodium silicate-activated, hydration properties, equivalent age modeling

Online: 17 April 2024 (08:06:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0025.v1

Analysis of the Evolution of Water Quality in Tanks according to the Connections and Operation Mode. Application to the most Suitable Design

Marta Hervás, Fernando Martínez-Alzamora, Pilar Conejos

Subject: Engineering, Civil Engineering Keywords: Simulation; water quality; water age; storage tanks; hydraulic networks

Online: 1 April 2024 (10:33:25 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202401.1332.v1

Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column

Zineb Fechtali-Moute, Sébastien Pomel

Subject: Biology And Life Sciences, Life Sciences Keywords: Free-Living Amoeba; cyst; age; water column; vertical distribution

Online: 17 January 2024 (13:38:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0040.v1

Discrete-time Survival Models with Neural Networks for Age-Period-Cohort Analysis of Credit Risk

Hao Wang, Anthony Graham Bellotti, Rong Qu, Ruibin Bai

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Credit risk; Survival model; Neural network; Age-Period-Cohort

Online: 3 January 2024 (03:53:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1534.v1

Mitigating Age-related Bias in Predictive Policing Algorithms

Ahmed Saud Almasoud

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: predictive policing; algorithms; fairness; age bias; strategic subject list

Online: 24 November 2023 (02:42:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1249.v1

The Relationship between Jealousy and Mate Retention Strategies in Romantic Relationships among Women during the COVID-19 Pandemic

Paulina Degiuli, Lea Andreis, Dario Vučenović

Subject: Social Sciences, Psychology Keywords: jealousy; partner retention strategies; romantic relationship; age; relationship length

Online: 20 October 2023 (08:06:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0658.v2

Assessment of Knowledge and Attitude of Reproductive Age Women towards Cervical Cancer Prevention in Selected Tertiary Institutions in Osun State, Nigeria

Oluwabunmi B. Erinsakin, Adeyemi O. Omoge, Oladunni Opeyemi, Idowu A. Olumakinde, Busayomi E. Folashayo, Michael N. Philip

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Knowledge; Attitude; Women of Reproductive Age; Cervical Cancer Prevention

Online: 17 October 2023 (11:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1322.v1

Age and Task Modulate Olfactory Sensitivity in the Florida Carpenter Ant Camponotus floridanus

Stephen T Ferguson, Isaac Bakis, Nicholas D Edwards, Laurence J Zwiebel

Subject: Biology And Life Sciences, Insect Science Keywords: hymenoptera; olfaction; odor coding; task allocation; age polyethism; aging

Online: 19 July 2023 (10:03:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0469.v1

Dynamical Analysis of an Age-Structured Sveir Model With Imperfect Vaccine

Yanshu Wang, Hailiang Zhang

Subject: Computer Science And Mathematics, Mathematical And Computational Biology Keywords: SVEIR model; latent age; imperfect vaccine; Lyapunov functions; stability

Online: 7 June 2023 (02:32:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0832.v1

Age of Onset Moderates the Association Between Total Antioxi-Dant Capacity and Cognitive Deficits in Patients With Drug-Naïve Schizophrenia

Jiaxin Li, Deyang Li, Junru Guo, Dongmei Wang, Xiangyang Zhang

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: schizophrenia; age of onset; TAOC; cognitive function; oxidative stress

Online: 24 April 2023 (06:22:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0152.v1

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Massimo Sangiorgi, Mariangela Valentina Puci, Allegra Rosa Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco Michelino Fiore, Armado Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Pietro Modugno, Maurizio Maiorano, Umberto Marcello Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni Maria Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio Stefano Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio Massimo Oddi, Alberto Maria Settembrini

Subject: Medicine And Pharmacology, Hematology Keywords: chronic limb-threatening ischemia; outcome; sex; age; limb salvage

Online: 8 December 2022 (09:39:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0278.v1

Association between Knowledge about Anemia, Food Consumption Behaviors, and Hematocrit Level among School-Age Children in Nakhon Si Thammarat Province, Thailand

Pastraporn Kaewpawong, Kiatkamjorn Kusol, Onuma Bunkarn, Sirigran Sutthisompohn

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: knowledge; food consumption behaviors; hematocrit level; school-age children

Online: 19 October 2022 (10:06:28 CEST)

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Anemia is a significant public health problem among children, especially school-age children because their body quickly produces red blood cells to provide sufficient blood volume with plasma expansion to maintain blood concentration. This research aimed to study the anemia situation, knowledge about anemia, food consumption behaviors, and the association between knowledge, food consumption behaviors, and hematocrit level among school-age children in primary school, in Thasala district, Nakhon Si Thammarat Province. This is a descriptive study among 408 students, Grades 4 to 6, aged 9-12 years. Research instruments included the demographic data of the children and their knowledge about anemia, food consumption behaviors, and hematocrit assessment. Data were analyzed using descriptive, Spearman’s rank correlation coefficient, and logistic regression statistics. The results revealed that 23.2% of the samples had anemia, whereas 22.22% had mild anemia and 0.98% had moderate anemia. The children knew about anemia, where the mean score was at a moderate level (Mean= 6.63; SD= 2.51) out of 10. The mean score on food consumption behaviors was in the moderate level (Mean= 17.49; SD= 3.68) out of 24. There were significantly positive correlations between the knowledge about anemia and the hematocrit level at a moderate level (r= 0.45, p< 0.001). Correlation analysis revealed moderate food consumption behaviors with the hematocrit level (r= 0.40, p< 0.001). When confirm with Logistic regression found that knowledge about anemia (OR = 9.15, 95% CI: 4.57-18.34), and food consumption behaviors (OR = 19.09, 95% CI: 9.71-37.53) were significantly associated with the hematocrit level. Conclusions: This study showed that knowledge and appropriate food consumption behaviors are associated with hematocrit levels. Enhancing knowledge about anemia and food consumption behaviors may be reduced the prevalence of anemia in school-age children. The health care providers in primary care should be encouraged children to have health education and eat sufficient food.

Preprint ARTICLE | doi:10.20944/preprints202206.0091.v1

Assessing the Effectiveness of Tobacco 21 Laws to Reduce Underage Access to Tobacco: Protocol for a Repeated Multi-Site Study

Mary Hrywna, Amanda Kong, Christopher Ackerman, Shawna Hudson, Cristine Delnevo

Subject: Public Health And Healthcare, Health Policy And Services Keywords: tobacco age of sale; tobacco policy; youth; young adults

Online: 7 June 2022 (03:44:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0367.v1

Differences in Citation Patterns across Areas, Article Types and Age Groups of Researchers

Marcelo Mendoza

Subject: Social Sciences, Library And Information Sciences Keywords: Citation patterns; Age groups of researchers; Types of publications.

Online: 17 August 2021 (15:09:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0434.v1

Clinical and Laboratory Characteristics of Kikuchi-Fujimoto Disease According to Age

Hye-Young Kim, Ha Young Jo, Seong Heon Kim

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Kikuchi-Fujimoto disease; histiocytic necrotizing lymphadenitis; prognosis; children; age

Online: 20 July 2021 (09:37:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0729.v1

Sergey Sudakov, Elena Alekseeva, Galina Nazarova, Valentina Bashkatova

Subject: Social Sciences, Psychology Keywords: age; behaviour; open field; physical activity; anxiety; Wistar rat.

Online: 30 June 2021 (10:57:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0536.v1

“What a Mobility-Limited World”: Design Requirements of an Age-Friendly Playable City

Liliana Vale Costa, Ana Isabel Veloso, Michael Loizou, Sylvester Arnab, Richard Tomlins, Arun Sukumar

Subject: Social Sciences, Urban Studies And Planning Keywords: playable city; age-friendly environments; games; mobility; active ageing

Online: 23 October 2018 (10:11:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0111.v1

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations

Jacqueline R. Halladay, Kaitlin C. Lenhart, Kimberly Robasky, Wendell Jones, Wayne F. Homan, Doyle M. Cummings, Crystal W. Cené, Alan L. Hinderliter, Cassandra L. Miller, Katrina E. Donahue, Beverly A. Garcia, Thomas C. Keyserling, Alice S. Ammerman, Cam Patterson, Darren A. DeWalt, Larry F. Johnston, Monte S. Willis, Jonathan C. Schisler

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: hypertension; GWAS; precision medicine; rural population; SNP-age interaction

Online: 12 January 2018 (07:34:37 CET)

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Background: As part of the Heart Healthy Lenoir Project, we developed a practice level intervention to improve blood pressure control. The goal of this study was: i) determine if single nucleotide polymorphisms (SNPs) that associate with blood pressure variation, identified in large case-control studies, are applicable to blood pressure control in subjects from a rural population; ii) measure the association of these SNPs with subjects’ responsiveness to the hypertension intervention; and iii) identify other SNPs that may help understand patient-specific responses to an intervention. Methods and Results: We used a combination of candidate SNPs and genome-wide analyses to test associations with either baseline systolic blood pressure (SBP) or change in systolic blood pressure one year after the intervention in two genetically defined ancestral groups: African Americans (AA) or Caucasian Americans (CAU). Of the 48 candidate SNPs, 13 SNPs associated with baseline SBP in our study; however, one candidate SNP, rs592582, also associated with a change in SBP after one year. Using our study data, we identified 4 and 15 additional loci that associated with a change in SBP in the AA and CAU groups, respectively. Our analysis of gene-age interactions identified genotypes associated with SBP improvement within different age groups of our populations. Moreover, our integrative analysis identified AQP4-AS1 and PADI2 as genes whose expression levels may contribute to the pleiotropy of complex traits involved in cardiovascular health and blood pressure regulation in response to an intervention targeting hypertension. Conclusions: Identification of SNPs associated with the success of a hypertension treatment intervention suggests that genetic factors in combination with age may contribute to an individual’s success in lowering SBP. If these findings prove to be applicable to other populations, the use of this genetic variation in making patient-specific interventions may help providers with making decisions to improve patient outcomes. Further investigation is required to determine the role of this genetic variance with respect to the management of hypertension such that more precise treatment recommendations may be made in the future as part of personalized medicine.

Preprint ARTICLE | doi:10.20944/preprints201608.0133.v1

Calorie Restriction Supplemented with Fish Oil Ameliorates Abnormal Metabolic Status in Middle-Aged Obese Women: An Open-Label, Parallel-Arm, Controlled Trial

Fasty Arum Utami, Hsiu-Chuan Lee, Chien-Tien Su, Shih-Yi Huang

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: calorie restriction; PUFA; meal replacement; metabolic syndrome; middle age

Online: 13 August 2016 (03:39:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0189.v1

The Global Burden of Type 2 Diabetes Attributable to Dietary Risks: Insights from the Global Burden of Disease Study 2019

Alina Ioana Forray, Mădălina Adina Coman, Ruxandra Simonescu-Colan, Andreea Isabela Mazga, Răzvan Mircea Cherecheș, Cristina Maria Borzan

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: type 2 diabetes mellitus; Global Burden of Disease Study; dietary risk factors; Age- Standardized Mortality Rate; Age-Standardized DALY Rate; Socio-Demographic Index

Online: 4 October 2023 (04:55:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0703.v1

Urine 5-Hydroxyindoleacetic Acid Negatively Correlates with Migraine Occurrence and Characteristics in the Interictal Phase of Episodic Migraine

Michal Fila, Jan Chojnacki, Marcin Derwich, Cezary Chojnacki, Elzbieta Pawlowska, Janusz Blasiak

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: migraine; tryptophan metabolism; serotonin; 5-hydroxyindoleacetic acid; migraine-related anxiety

Online: 10 April 2024 (10:34:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0679.v1

MicroRNAs Monitoring in Human Alveolar Macrophages from Patients with Smoking-Related Lung Diseases: A Preliminary Study

Davida Mirra, Renata Esposito, Giuseppe Spaziano, Liberata Sportiello, Francesca Panico, Antonio Squillante, Maddalena Falciani, Ida Cerqua, Luca Gallelli, Erika Cione, Bruno D’Agostino

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: miRNA; copd; alveolar macrophages; smoking-related lung diseases; lung cancer

Online: 10 April 2024 (07:21:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1231.v1

The Effect of Exercise on Reducing Lymphedema Severity in Breast Cancer Survivors

Lian Yanxue, Simran Sandhu, Yamikani Asefa, Ananya Gupta

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Breast cancer-related lymphedema; exercise; physical activity; Yoga; resistance exercise

Online: 21 March 2024 (02:18:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.2019.v1

Quantitative Analysis of Collagen and Apoptosis Related Protein on 1064 nm Laser-Induced Skin Injury

Qiong Ma, Yingwei Fan, Yufang Cui, Zhenkun Luo, Hongxiang Kang

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: infrared laser; laser-induced skin wound; collagen; apoptosis related protein

Online: 29 January 2024 (10:31:52 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.1147.v1

Prevention of Breast Cancer-Related Lymphedema: An Up-to-Date Systematic Review of Different Surgical Approaches

Domenico Pagliara, Federica Grieco, Silvia Rampazzo, Nicola Pili, Pietro Luciano Serra, Roberto Cuomo, Corrado Rubino

Subject: Medicine And Pharmacology, Surgery Keywords: Breast cancer- related lymphedema; lymphatic surgery; microsurgery; primary prevention; lymphedema

Online: 15 December 2023 (06:20:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1076.v1

Dillema of Multi-Platform Ride-Hailing Drivers in Yogyakarta: Between Economic Demands and Psychological Impact in Achieving Well-Being

Daffa Nurrahmad, Salma Rahmasari, Doni Pradana, Syahriza Utomo, Mutiara Putri, Ardian Afandi

Subject: Social Sciences, Psychology Keywords: ride-hailing driver; partner; work-related stress; psychology; well-being

Online: 14 December 2023 (10:48:51 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1315.v1

Methylation of the Vitamin D Receptor (VDR) gene in human disorders

Beatrice Gasperini, Angela Falvino, Eleonora Piccirilli, Umberto Tarantino, Annalisa Botta, Virginia Veronica Visconti

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Vitamin D receptor (VDR); Epigenetics; DNA methylation; VDR-related diseases

Online: 21 November 2023 (10:47:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0196.v1

Molecular Identification of Fungal Species by Multiplex-qPCR in Candidal Vulvovaginitis Specimens and Antifungal Susceptibility

Inés Arrieta-Aguirre, Pilar Menéndez-Manjón, Giulia Carrano, Ander Diez, Íñigo Fernandez de Larrinoa, María-Dolores Moragues

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Vulvovaginal Candidiasis; qPCR; Candida species, antifungal susceptibility, resistance-related mutations

Online: 3 November 2023 (04:02:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1229.v1

Pyeloureteral Junction Obstruction: Underdevelopment or Fibrosis?

Ramune Zilinskaite Tamasauske, Vytis Kazlauskas, Povilas Barasa, Natalija Krestnikova, Darius Dasevicius, Vytautas Bilius, Gilvydas Verkauskas

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Pyeloureteric junction; Pyeloureteric junction obstruction; Gene expression; Fibrosis related genes

Online: 17 August 2023 (09:08:25 CEST)

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Introduction: congenital ureteral stenosis is one of the leading causes of impaired urinary drainage and subsequent dilatation of urinary collecting system, known as hydronephrosis or ureterohy-dronephrosis. Mechanism that leads to obstruction is not clearly known. Multiple studies in rat models have shown increased angiotensin 11 and TGFβ levels in obstructed ureteral tissue. The aim of the study is to investigate expression of fibrosis related genes in obstructive and normal ureteral tissue. Material and methods: it is a monocentric study in which nineteen patients were selected prospec-tively. 17 patients of which underwent Hynes-Anderson pyeloplasty due to the PUJO, 2 patients underwent ureteroneocystostomy due to ureterovesical junction obstruction (UVJO) and 6 patients were chosen for control group: 5 underwent nephrectomies due to the kidney tumor and 1- upper pole heminephrectomy due to the duplex kidney with normal pyeloureteric junctions in all. Tissue RNA was chemically extracted after freezing the biopsy samples in liquid nitrogen, with cDNA synthesis performed immediately after nucleic acid isolation. qPCR to evaluate the relative expres-sion of Tgfb1, Mmp1, Timp1, Pai1, Ctgf and Vegfa was performed. Expression levels of Gapdh and Gpi genes (geometric average) were used to calculate the relative expression of the investigated genes. Outliers were removed prior to calculating confidence intervals for the experimental groups, and Wilcoxon rank-sum test was performed to determine statistical significance of the differences. Results: significant differences between healthy and stenotic tissue samples in Ctgf gene expression levels were observed, with the samples from afflicted tissue showing lower expression. No statistical difference in expression levels of Tgfb1, Timp1, Vegfa, Mmp1, Pai1 was found. Discussion and conclusions: These findings suggest that tissue fibrosis similar to other tissues and organs is not the leading cause of stenosis, at least at the moment of surgery. Decreased CTGF ex-pression is indicative of developmental origin of obstruction.

Preprint ARTICLE | doi:10.20944/preprints202306.1970.v1

The ATP6V1B2 DDOD/DOORS-Associated p.Arg506* Variant Causes Hyperactivity and Seizures in Mice

Justine Rousseau, Samuel Boris Tene Tadoum, Marisol Lavertu Jolin, Thi Tuyet Mai Nguyen, Norbert Fonya Ajeawumg, Ann M Flenniken, Laury Nutter, Igor Vukobradovic, Elsa Rossignol, Philippe M Campeau

Subject: Biology And Life Sciences, Life Sciences Keywords: Atp6v1b2; R506*; mice; locomotor hyperactivity; diminished anxiety-related behavior; epilepsy

Online: 28 June 2023 (08:34:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0221.v1

Assembly of Two Small Body-Sized West Pacific Sciaenid Genomes

Zibin Liang, Jie Yang, Feiang Xie, Yifan Wang, Junlai Mao, Wen Wang, Wansuk Senanan, Yongjiu Chen

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Larimichthys polyactis; Collichthys lucidus; genome; phylogeny; ortholog; growth-related gene

Online: 13 February 2023 (15:08:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202207.0260.v1

Evaluating the Sensitivity of Heat Wave Definitions Among North Carolina Physiographic Regions

Jagadeesh Puvvula, Azar Abadi, Kathryn Conlon, Jared Rennie, Hunter Jones, Jesse Bell

Subject: Biology And Life Sciences, Other Keywords: Heat Wave; Heat-related illness; Early heat-health warning systems

Online: 18 July 2022 (10:14:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202112.0345.v1

Windtech – A Sensory Device for ‘Cold’ Sensation Measurements

Amir Leyli, Hassan Khawaja, Ståle Antonsen, Daniel Swart

Subject: Engineering, Automotive Engineering Keywords: Cold Sensation; Heat Loss; Cold Related Risks; Real Feel Temperature

Online: 21 December 2021 (14:06:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202005.0341.v1

Role of Advanced Glycation End Products on Aortic Calcification in Patients with Type 2 Diabetes Mellitus

Pilar Sanchis, Rosmeri Rivera, Regina Fortuny, Carlos Rio, Miguel Mas-Gelabert, Marta Gonzalez-Freire, Felix Grases, Luis Masmiquel

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: AGEs; aortic calcification; type 2 diabetes mellitus; diabetes-related complications

Online: 21 May 2020 (09:46:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0416.v1

Menstruation Distress Is Strongly Associated with Hormone-Immune-Metabolic Biomarkers

Chutima Roomruangwong, Sunee Sirivichayakul, Andressa Keiko Matsumoto, Ana Paula Michelin, Laura de Oliveira Semeao, João Victor de Lima Pedrao, Decio S. Barbosa, Estefania G. Moreira, Michael Maes

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: menstrual cycle-related syndrome; neuroimmunomodulation; biomarkers; inflammation; oxidative stress; antioxidants

Online: 29 March 2020 (03:22:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201911.0133.v1

Hospital Malnutrition, A Call for Political Action: A Public Health and nutritionDay Perspective

Michael Hiesmayr, Silvia Tarantino, Sigrid Moick, Alessandro Laviano, Isabella Sulz, Mohamed Mouhieddine, Christian Schuh, Dorothee Volkert, Judit Simon, Karin Schindler

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: malnutrition; disease related malnutrition; risk factors; nutrition care; mortality; recommendations

Online: 12 November 2019 (16:46:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201909.0107.v1

Compatibility and Stability of Daptomycin Lock Solutions in Combination with Gentamicin, Azithromycin, Heparin and Trisodium Citrate

P. Brandon Bookstaver, Padmavathy Premnath, Kayisa Wright, Campbell McInnes

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: daptomycin; antibiotic lock therapy; gentamicin; azithromycin; catheter-related bloodstream infections

Online: 10 September 2019 (10:43:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0207.v1

Assessing Language-Induced Motor Activity through Event Related Potentials and the Grip Force Sensor, an Exploratory Study

Fernanda Pérez-Gay Juárez, David Labrecque, Victor Frak

Subject: Social Sciences, Behavior Sciences Keywords: language; motor system; event related potentials; action simulation; embodied semantics

Online: 21 January 2019 (11:03:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0359.v1

Chlorpyrifos- and Dichorfos-Induced Oxidative and Neurogenic Damage Elicits Neuro-Cognitive Deficits and Increases Anxiety-Like Behaviors in Wild-Type Rats

Aminu Imam, Nafeesah Abdulkareem Sulaiman, Aboyeji Lukuman Oyewole, Samson Chengetanai, Victoria Williams, Musa Iyiola Ajibola, Royhaan Olamide Folarin, Asma'u Shehu Muhammad, Sheu-Tijani Toyin Shittu, Salihu Moyosore Ajao

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: oxidative damage; organophosphates; neurotoxicity; spatial working memory; anxiety-related behaviors

Online: 16 October 2018 (12:04:13 CEST)

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The mechanization of agricultural activities has led to indiscriminate deposition of toxic xenobiotics, including organophosphates in the biomes, and this has led to intoxication characterized with deleterious oxidative and neuronal changes. This study investigated the consequences of oxidative and neurogenic disruptions that follow exposure to two organophosphates, chlorpyrifos (CPF) and dichlorvos (DDVP) on neuro-cognitive performance and anxiety-like behaviors in rats Thirty-two adult male Wistar rats (150 – 170g) were randomly divided into 4 groups, orally exposed to normal saline (NS), DDVP (8.8mg/kg), CPF (14.9mg/kg) and DDVP+CPF for 14 consecutive days. On day 10 of exposures, anxiety-like behaviors and amygdala dependent fear learning were assessed using Open Field and Elevated Plus Maze paradigms respectively, while spatial working memory was assessed on day 14 in the Morris water maze paradigm, following 3 training trials each on days 11, 12 and 13. On day 15, the rats were euthanized, and their brains excised, hippocampus and amygdala removed, 5 of which were homogenized and centrifuged to analyze nitric oxide (NO) metabolites, total reactive oxygen species (ROS), and acetylcholinesterase (AChE) activity, and the other three processed for histology (cresyl violet stain) and proliferative marker (Ki67 immunohistochemistry). Marked (p≤0.05) loss in body weight, AChE depletion, and overproduction of both NO and ROS were observed after repeated exposure to individual and combined doses of CPF and DDVP. Insults from DDVP exposure appeared more severe owing to the observed greater losses in the body weights of exposed rats. There was also a significant (p≤0.05) effect on the cognitive behaviors recorded from the exposed rats, and these deficits were related to the oxidative damage and neurogenic cell loss in the hippocampus and the amygdala of the exposed rats. Taken together, these results provided an insight that oxidative and neurogenic damages are central to the severity of neuro-cognitive dysfunction and increased anxiety-like behaviors that follow organophosphate poisoning.

Preprint ARTICLE | doi:10.20944/preprints202404.0774.v1

Junxia Li, Zhenguo Wang, Liujia Wang, Xiayuan Wang, Dong He, Xinming Duan, Chunxiang Zhang, Youshe Ren, Chunhe Yang

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: cashmere goat; cashmere production; secondary hair follicle; age; oxidative stress

Online: 11 April 2024 (10:12:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1497.v1

Ethnic Representation Matters: Investigating Bias in Facial Age Prediction Models

Nenad Panić, Marina Marjanović, Timea Bezdan

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Facial recognition; Age prediction; Convolutional Neural Network (CNN); Ethnicity bias

Online: 26 March 2024 (08:15:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0998.v1

Development and Implementation of Virtual Reality Application: Age-Friendly Health System Scenario

Sweta Tewary, Oksana Shnayder, Marie Dezine, Naushira Pandya

Subject: Public Health And Healthcare, Primary Health Care Keywords: virtual reality; age friendly health systems; medical education; older adults

Online: 19 February 2024 (15:45:44 CET)

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INTRODUCTION: With an increase in the aging population, the application of evidence-based practice in geriatric education can strengthen knowledge, skills, and clinical experience for healthcare students caring for older adults. Age Friendly Health Systems (AFHS) is one of the frameworks founded on providing evidence-based and low-risk care centered on what matters most to older adults, their families, and caregivers. Virtual Reality (VR) platforms are gaining popularity due to their ability to provide an immersive, hands-on learning experience resembling an actual medical practice or care setting. Immersive learning enhances students’ sensory perceptions, promoting an innovative and engaging way of acquiring concepts that are difficult to teach in real life. This study aimed to design, develop, implement, and evaluate a case-based training module highlighting AFHS and educating medical students on the 4Ms approach in geriatric care (What Matters, Medication, Mentation, and Mobility). METHODOLOGY: The project was a feasibility study completed in two phases. Phase one included planning and development of a case-based scenario incorporating 4Ms of AFHS. Phase two included implementing and evaluating the VR training module into the geriatric curriculum for medical students. RESULTS: The final VR case displays a hospital and post-acute setting where an elderly patient is admitted for a hip fracture. Students learn how to triage and treat patients from admission to discharge while demonstrating their knowledge of AFHS. Approximately 10% of students completed the evaluation survey, and preliminary results indicate significant knowledge change in pre-post scenario-based training on AFHS. CONCLUSION: The VR education platform and embedded scenario promise an innovative adaptation of technology in learning the concepts of the 4Ms of AFHS. However, future studies should explore VR education with clinical assessment evaluation to ensure competence in providing Age-Friendly care.

Preprint REVIEW | doi:10.20944/preprints202402.1022.v1

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Cecilia Salzillo, Roberta Basile, Gerardo Cazzato, Giuseppe Ingravallo, Andrea Marzullo

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: hospital autopsy; modern age; clinical diagnosis; autopsy diagnosis; Public Health

Online: 19 February 2024 (08:22:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1799.v1

Suboptimal Nutritional Status of School-Age Children in Addis Ababa: Evidence from the Analysis of Sociodemographic, Environmental, and Behavioral Factors

Yimer Mihretie Mihretie, Abebe Ayelign, Tadesse Alemu Zerfu

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: ; Addis Ababa; dietary factors; nutritional status; school-age children

Online: 25 January 2024 (09:53:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0350.v1

Human Age Estimation from Face Images with Deep Convolutional Neural Networks Using Transfer Learning

Gilbert George, Chandrashekhar Uppin, Usman Abubakar Bello

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Convolution neural network; Deep Learning; Facial Age; Regression; Transfer learning

Online: 4 January 2024 (07:41:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1081.v1

Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals

Süheyl Poçan, Levent Karakaş

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: 3 tesla magnetic resonance; age, healty volunteers; elastography; splenic stiffness

Online: 17 October 2023 (11:20:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1069.v1

Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals

Süheyl Poçan, Levent Karakaş

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: 3 tesla magnetic resonance; age; healty volunteers; elastography; splenic stiffness

Online: 17 October 2023 (11:11:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0861.v1

Pattern of Presentation and Risk Factor Prediction of Acute Myocardial Infarction in Kosovo

Afrim Poniku, Arlind Batalli, Dua Shita, Zarife Rexhaj, Arlind Ferati, Rita Leka, Artan Bajraktari, Genc Abdyli, Edmond Haliti, Pranvera Ibrahimi, Shpend Elezi, Faik Shatri, Ibadete Bytyçi, Michael Henein, Gani Bajraktari

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Myocardial infarction; risk factors; smoking; diabetes; arterial hypertension; age; gender

Online: 14 September 2023 (02:34:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.0670.v1

Precision and Accuracy of Radiological Bone Age Assessment in Children among Ethnical Groups

Sebastián Eustaquio Martín Pérez, Isidro Miguel Martín Pérez, Jesús Vega González, Ruth Molina Suárez, Coromoto León Hernández, Fidel Rodríguez Hernández, Mario Ulises Herrera Perez

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: diagnostic imaging; radiography; age determination by skeleton; racial group; children

Online: 11 September 2023 (11:11:23 CEST)

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Introduction: Determination of radiological bone age (BA) is a diagnostic method that consists of estimating chronological age (CA) from the bone maturation of children. Although environmental and hormonal factors can interfere with bone ossification, the process is essentially dependent on ancestral inheritance. These ethnic backgrounds are not usually considered, which can lead to biased interpretations and inadequate decision-making by pediatricians or forensic experts. The objective of this study was to determine the precision and accuracy of these radiological procedures among different ethnic groups. Methods: A qualitative systematic review carried out following MOOSE statement and previously registered in the International Prospective Registry of Systematic Reviews PROSPERO (CRD42023449512). Search was performed in MEDLINE (PubMed) (n=561), Cochrane Library (n=261), CINAHL (n=103), Web of Science (WOS) (n=181) and public institutional repositories (n=37) from inception to 31st December 2022 using Mesh as “Diagnostic Techniques and Procedures”, “Diagnostic imaging”, “Radiography”, “Age Determination by Skeleton” and free terms combining with booleans “AND” and “OR”. PEDro scale, and Risk of Bias in non-randomized Studies of Exposure (ROBINS-E) were used to assess methodological quality and risk of bias of included studies respectively. Results: 51 articles (n=19,531) were included according to the inclusion criteria previously established. There was a good to moderate methodological quality and a high to very high risk of bias. Skeletal methods for determining BA were precised in terms of intra-observer and inter-observer reliability in all ethnic groups. Regarding to accuracy of Skeletal methods in Caucasians and Hispanic children, GPA was accurate at all ages, but in youths, TW3 RUS could be a consistent alternative. In Asian and Arab, GPA and TW3 overestimated BA in adolescents near adulthood. In African youths, GPA overestimated BA while TW3 was more accurate in estimating CA. Dental and Cervical radiographic methods are equally precise but lesser accurate than Skeletal BA determination. Conclusion: Skeletal radiographic methods GPA and TW3 are both precise for BA determination among all ethnical groups, but their accuracy in estimating CA can be altered by racial bias.

Preprint ARTICLE | doi:10.20944/preprints202306.0653.v1

Determinants of Child Nutritional Status among Scheduled Tribes in West Bengal

Manabindra Barman, Dr. Indrajit Roy Chowdhury

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Scheduled tribe; Children; Nutritional status; Under 5years age; Determinant factors

Online: 9 June 2023 (03:04:37 CEST)

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Malnutrition is the main cause of child mortality in developing nations, especially in Sub-Saharan Africa and South Asian countries. This undernutrition status is predominantly higher among primitive tribal (ST) children under 5 years of age. The nutritional status of tribal children is a serious concern in India. For this, there should be intends to examine the prevalence and determinants of primitive tribal children's nutritional status. To investigate the effect of household, child’s & maternal characteristics on biological children under 5 years of age. The study aims to find out the association between some selected determinants on scheduled tribe child’s nutritional status. The study used some selected variable of scheduled tribe mothers, household characteristics and their children anthropometric indices from DHS datasets of India, which was published by the NFHS datasets of India. In this study People datasets and Children (Under 5 years of age) of interviewed women file datasets of NFHS-IV & V is taken. The datasets of West Bengal, ST mothers, and their child into consideration as per the research interest. Then to analyze the determinants of ST children (U5 age) nutritional status, some determinant factors are taken from mothers, children and household characteristics. Children’s stunting, wasting and underweight as dependent variable and the mothers, child’s and household’s characteristics as independent variable. The statistical analysis was done by using Pearson Chi square test used to analyze the association between dependent and independent variables. The study results shows that the mother’s educational status, child’s age, birth order, size of child at birth, type of residence had significant associations with stunting. Mother's anemia status and mother age had significant associations with wasting. Mother education, currently breastfeeding, child age, sex of the child, birth order, size of child at birth, type of residence, wealth, toilet facility, and cooking fuel shows a significant association with underweight. The results found that many determinant factors had a significant role among ST children's (U5 age) nutritional status. Thus, the findings will help to achieve tentative resource allocation, and utilization through various programs and policies to improve the ST children (U5 age) nutritional status. There is a need to take a multisectoral and multidimensional approach to develop for those primitive tribal children.

Preprint ARTICLE | doi:10.20944/preprints202305.1011.v1

Prevalence of Vitamin B₁₂ and Folate Deficiencies in Indian Children and Adolescents

Tattari Shalini, Raghu Pullakhandam, Santu Ghosh, Bharati Kulkarni, Hemalatha Rajkumar, Harshpal S Sachdev, Anura V Kurpad, Geereddy Bhanuprakash Reddy

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Vitamin B12 deficiency; Folate deficiency; School-age children; Adolescents; CNNS

Online: 15 May 2023 (09:45:12 CEST)

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Deficiencies of vitamin B12 (B12) and folate (FA) are of particular interest due to their pleiotropic role in 1-carbon metabolism. In addition to adverse birth outcomes, deficiencies of B12 and FA, or an imbalance in FA/B12 status, are linked to metabolic disorders. Indian diets that are predominantly plant food-based could be deficient in these vitamins, but there are no national estimates of the prevalence of B12 and FA deficiency in Indian children and adolescents, nor of their associations with age, sex, and growth indicators. The recent Comprehensive National Nutrition Survey (CNNS-2016-18) provided estimates of the prevalence of B12 and FA deficiency at the national and state level among preschool (1-4y: 9,976 and 11,004 children respectively), school-age children (5-9y: 12,156 and 14,125) and adolescents (10-19y: 11,748 and 13,621). Serum B12 and erythrocyte FA were measured by the direct chemiluminescence method and their deficiency was defined using WHO cut-offs. The prevalence of B12 and FA deficiency was high among adolescents (31.0%, CI: 28.7-33.5 and 35.6%, CI: 33.1-8.2), compared to school-age (17.3%, CI: 15.4-19.3 and 27.6%, CI: 25.5-29.9) and preschool children (13.8%, CI: 11.7-16.2 and 22.8%, CI: 20.5-25.2, respectively). The prevalence of both B12 and FA deficiency was significantly higher by 8 and 5% points respectively, in adolescent boys compared to girls. The prevalence of B12 deficiency was higher in moderately stunted school children (by 18.9% points) than in normal children, but no such difference was observed for FA deficiency. There was wide regional variation in the prevalence of B12 and FA deficiency, but no rural-urban differences were observed across all age groups. The national prevalence of B12 deficiency among preschool or school-age children was <20% (the cut-off that indicates a public health problem). However, FA deficiency in these age groups and both FA and B12 deficiencies in adolescents were >20%, which warrants further investigation.

Preprint ARTICLE | doi:10.20944/preprints202305.0165.v1

Computed Tomographic Features of Thymus Gland in Dogs: Correlation with Age, Gender, Breed and Body Fat Content

Mohammad Molazem, Sarang Soroori, Alireza Bahonar, Saghar Karimi

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Computed tomography, Thymus Gland, Dog, Age, Gender, Breed, Body Fat

Online: 4 May 2023 (02:59:54 CEST)

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: Background: The thymus gland is the first lymphoid organ formed to regulate a newborn's immunity. It reaches its maximum size during puberty, after which it undergoes an atrophic procedure called involution, but its ability to grow again in response to some stresses, such as infections, neoplasia, surgeries, chemotherapy, and radiotherapy is maintained. There is not any comprehensive study on computed tomographic features of thymus gland in dogs. So, the goal of the present study is to achieve some information about thymus gland using computed tomography as a non-invasive method. Methods: One hundred and fifty dogs classified in 5 age groups and 2 breed groups were entered to this study and the thymus gland was evaluated using 2-slice computed tomography machine. The inclusion criteria for the present study were having normal complete blood count, plain and post-contrast CT scan examination of thoracic region and no history of neoplasia, chemotherapy or radiotherapy. The visibility, density, enhancement, grade, size, volume, shape, borders and lateralization of the thymus were evaluated and statistical analysis were performed. The effect of obesity on thymic grade and volume were also investigated. Results: The visibility, density, dorsal length, volume and grade decreased with increasing age. The thymic shape and lateralization were mostly wedge-shaped and left sided respectively. The borders became concave with aging and increasing body fat content caused to increase fatty degeneration of thymus. Conclusions: Declining of thymic density, grade, size and volume with aging was related to thymic involution and fatty degeneration was accelerated by increasing body fat content. Females and Males were different only in thymic shape and small and large breeds were different only in thymic volume. The thymus was visible in some geriatric dogs with no underlying disease. We hope that the present work can be used by radiologists in reading thoracic computed tomography but investigation of thymic characteristics in dogs with neoplasia and history of chemotherapy, radiotherapy and thoracic surgeries can complete this study.

Preprint ARTICLE | doi:10.20944/preprints202205.0409.v1

Are There Sex Differences in Self-Reported Childhood Maltreatment in Major Depressive and Bipolar Disorders? A Retrospective Cross-Sectional Study

Daniela Caldirola, Tatiana Torti, Francesco Cuniberti, Silvia Daccò, Alessandra Alciati, Koen Schruers, Giovanni Martinotti, Domenico De Berardis, Giampaolo Perna

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: childhood trauma; major depressive disorder; bipolar disorder; sex difference; age

Online: 31 May 2022 (03:39:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0192.v1

Inequalities in Temporal Effects on Cervical Cancer Mortality in States in Different Geographic Regions of Brazil: An Ecological Study

Karina Cardoso Meira, Carinne Magnago, Angelo Braga Mendonça, Stephane Fernanda Soares Duarte, Pedro Henrique Oliveira de Freitas, Juliano dos Santos, Dyego Leando Bezerra de Souza, Taynãna César Simões

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: uterine cervical neoplasms; mortality; age-period-cohort analysis; forecasting; Brazil

Online: 16 February 2022 (05:03:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0506.v1

A Retrospective Cohort Study of the Clinical Features, Pathological Characteristics, and Molecular Classification in Reproductive Age Patients with Endometrial Cancer who Experienced Unsuccessful Fertility-sparing Treatment

Tong Yu, Xi-Wen Zhang, Ping-Li Sun, Abdulkarim Mohamed Farah, Yan Jia

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: endometrial cancer; fertility-sparing management; molecular classification; reproductive age; pregnancy

Online: 26 November 2021 (12:42:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0446.v1

Non-Modifiable Risk Factors (Age and Sex), Stroke Types, and Outcomes in Rivers State, Nigeria: A Retrospective Hospital-Based Study

Osborne Ikechuckwu Osuegbu, Foluke Olukemi Adeniji, Golden Chukwuemaka Owhonda, Rogers Bariture Kanee, M Alblihed, Gaber El-Saber Batiha, Eric Osamudiamwen Aigbogun

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Age; Sex; Stroke Types; Outcomes; SEM; Tertiary Hospitals; Rivers State

Online: 20 July 2021 (11:45:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0696.v1

Revealed Preferences of Fourth Graders When Requesting Face-to-Face Help While Doing Math Exercises Online

Roberto Araya, Raúl Gormaz

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Help Seeking; Same-age Peer Tutoring; Revealed Preferences; Data analytics

Online: 29 June 2021 (11:36:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0392.v1

Prevalence of Controlled Systemic Hypertension and Its Associated Risk Factors among Hypertensive Patients at Mbeya Zonal Referral Hospital, Tanzania.

Samson Peter Mvandal, Victor Jastin Mwinuka

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Age; adherence; anti-hypertensive; Controlled hypertension; clinic; hypertension; Prevalence; Systemic

Online: 17 May 2021 (15:57:01 CEST)

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Working Paper REVIEW

A Systematic Review of Neuroimaging and Acute Cannabis Exposure in Age-of-Risk for Psychosis

Lani Cupo, Eric Plitman, Elisa Guma, M Mallar Chakravarty

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: systematic review; cannabis; neuroimaging; age-of-onset psychosis; psychosis; schizophrenia

Online: 14 May 2021 (09:58:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0589.v1

Compaction Model for Shale in Differences of Geological Ages Using A 3D Empirical Relationship in Northeastern Thailand

Avirut Puttiwongrak, Syukratun Nufus, Chaiyaphruk Bunprasert, Pham Huy Giao, Sakanann Vann, Thongchai Suteerasak, Nophea Sasaki

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Shale compaction; Geological age; Thailand shale; Compaction model; Standard curve

Online: 21 April 2021 (16:50:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0478.v1

Quality of Life: Changes in Self Perception in People with DS who Participate in Laliga Genuine Santander. Self Reports and External Reports

Rocío Camacho, Cristina Castejón-Riber, Francisco Requena, Julio Camacho, Arturo Gallego, Roberto Espejo, Amaranta De Miguel-Rubio, Begoña M. Escribano, Estrella I. Agüera

Subject: Social Sciences, Psychology Keywords: Down's Syndrome; perception; quality of life; sport; age; gender; scale

Online: 18 December 2020 (16:17:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0090.v1

Tapering, Tree Rings and Biomass Production of Pinus roxburghii (Sarg.): A Dendrochronological Study

Hari Prasad Pandey, Narayan Prasad Pokhrel

Subject: Biology And Life Sciences, Forestry Keywords: age; coring sample; forest productivity; Nepal; P. roxburghii; stand structure

Online: 4 September 2020 (08:08:30 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202005.0005.v1

Age-Adaptive and Gender-Balanced Social Interventions Might Be Stepping Stones to the Next ‘New Normal’ in COVID-19 Outbreak

Carlo Vittorio Cannistraci, Ilaria Capua

Subject: Biology And Life Sciences, Virology Keywords: social intervention; COVID-19; health policy; public health; age; gender

Online: 2 May 2020 (12:04:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0051.v3

Bulk and Single-Cell Transcriptomics Identify Tobacco-Use Disparity in Lung Gene Expression of ACE2, the Receptor of 2019-nCov

Guoshuai Cai

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Wuhan 2019-nCov; ACE2; expression; susceptibility; race; age; gender; smoking; single cell

Online: 2 March 2020 (01:38:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201912.0380.v1

Physical Activity in Elderly Kidney Transplant Patients with Multiple Renal Arteries

Armando Calogero, Caterina Sagnelli, Gaia Peluso, Antonello Sica, Maria Candida, Silvia Campanile, Gianluca Minieri, Paola Incollingo, Massimiliano Creta, Luigi Pelosio, Vincenzo Tammaro, Alessandro Scotti, Akbar Jamshidi, Marcello Caggiano, Evangelista Sagnelli, Concetta Anna Dodaro, Nicola Carlomagno, Michele Santangelo

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: physical activity; kidney transplantation; elder age; vascular anomalies; marginal kidneys

Online: 29 December 2019 (11:06:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints201908.0236.v1

Growth Opportunities and Earnings Quality from Emerging Economies

Jerry Danjuma kwarbai, Rufus Ishola Akintoye, Festus Fola Adegbie, Apollos Nwabuisi Nwaobia

Subject: Business, Economics And Management, Accounting And Taxation Keywords: earnings quality; growth opportunities; discretionary accruals; corporate age; corporate size

Online: 23 August 2019 (04:40:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0260.v1

Evaluation of Questionnaire Data Views on the Design of Living Space for Different Situations in Life

Carsten Brausch, Dušan Katunský, Jana Katunská

Subject: Engineering, Civil Engineering Keywords: interior design; questionare; life situation; data evaluation; different age groups

Online: 23 April 2019 (13:12:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1597.v1

Bidirectional Two-Sample Mendelian Randomization Analysis Identifies Causal Associations between Gut Microbiome and Sleep-Related Traits

Mingxia Zhai, Weichen Song, Zhe Liu, Wenxiang Cai, Guanning Lin

Subject: Biology And Life Sciences, Other Keywords: Gut Microbiome; Bacterial Pathways; Sleep-related Traits; Mendelian Randomization; Causal Relationship

Online: 28 February 2024 (10:53:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1709.v1

Different Shades of Green: An Analysis of the Occupational Health and Safety Risks Faced by Wind Farm Workers

Liliana Cunha, Daniel Silva, Mariana Macedo

Subject: Social Sciences, Psychology Keywords: green jobs; wind turbines; psychosocial risks; health-related risks; work sustainability

Online: 24 January 2024 (07:13:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1529.v1

Brain Wearables: Validation Toolkit for Ear-Level EEG Sensors

Guilherme Correia, Michael J Crosse, Alejandro Lopez Valdes

Subject: Engineering, Bioengineering Keywords: Wearable Electroencephalography; Ear-EEG; Validation; Toolkit; EEG Phantom; Event-Related Potentials

Online: 20 December 2023 (10:23:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0430.v1

Thanh Xuan Nguyen, Anh Huynh Phuong Nguyen, Huong Thi Thu Nguyen, Thu Thi Hoai Nguyen, Hoa Lan Nguyen, Robert Joel Goldberg, Janani Thillainadesan, Vasi Naganathan, Huyen Thi Thanh Vu, Luc Viet Tran, Anh Trung Nguyen

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Vietnam; dementia; older adult; quality of life; related factors; nursing home

Online: 6 December 2023 (15:39:13 CET)

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Preprint REVIEW | doi:10.20944/preprints202309.2079.v1

Energy literacy: a systematic review of scientific literature

Oscar Sánchez Santillán, Karla Graciela Cedano Villavicencio

Subject: Environmental And Earth Sciences, Other Keywords: Energy literacy; energy reviews; energy-related knowledge; energy transitions; energy education.

Online: 3 October 2023 (03:21:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1046.v1

Drought Stress-Related Reprogramming of Gene Expression in Barley Leaves Involves Loading of ABA-Related Genes with Euchromatic Marks H3K4me3 and H3K9ac

Charlotte Ost, Xuan Hieu Cao, Thuy Linh Nguyen, Axel Himmelbach, Martin Mascher, Nils Stein, Klaus Humbeck

Subject: Biology And Life Sciences, Plant Sciences Keywords: ABA-related genes; drought stress; epigenetics; euchromatic histone modifications; Hordeum vulgare

Online: 17 July 2023 (04:07:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0241.v1

Six-year-old Ecological Concrete in a Marine Environment: a Case Study

Amit Kenny, Ela Ofer Rozovsky

Subject: Engineering, Civil Engineering Keywords: Ecological concrete; Cement/cementitious materials; Durability-related properties; Carbonation; Chloride; Diffusion

Online: 14 December 2022 (02:03:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202206.0360.v1

The Effect of Small Particulate Matter on Tourism and Related SMEs in Chiang Mai, Thailand

Phisek Srinamphon, Sainatee Chernbumroong, Korrakot Tippayawong

Subject: Business, Economics And Management, Business And Management Keywords: tourism and related; SMEs; small particulate matters; association rules; data mining

Online: 27 June 2022 (10:24:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0257.v1

Cautionary Observations Concerning the Introduction of Psychophysiological Biomarkers into Neuropsychiatric Practice

Paul E. Rapp, Christopher Cellucci, David Darmon, David Keyser

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: biomarkers; electroencephalography; event related potentials; heart rate variability; diagnosis; sensitivity; specificity

Online: 17 March 2022 (15:19:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202105.0772.v1

Wing Lok Chan, Horace Cheuk-Wai Choi, Patty Pui-Ying Ho, Johnny Kin-San Lau, Rosa Pui-Ying Tse, Joyce Au, Vivian Lam, Ronald Liu, Isaac Ho, Charlotte Wong, Ben Cheung, Eric Lam, Daryn Chow, Ka-On Lam, Kwok-Keung Yuen, Dora Lai-Wan Kwong

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Immune checkpoint inhibitors; immune-related endocrine dysfunction; hypothyroidism; targeted therapy; malignancy

Online: 31 May 2021 (12:49:40 CEST)

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Abstract Background The number of immune-related endocrine dysfunctions (irEDs) has concurrently increased with the widespread use of immunotherapy in clinical practice and further expansion of the approved indications for immune checkpoint inhibitor (ICI) combinations using different modalities of anti-cancer treatment. Method A retrospective analysis was conducted on consecutive patients >18 years of age with advanced solid malignancies who had received at least one dose of anti-programmed cell death protein 1 (anti-PD-1) and/or anti-CTLA4 antibodies between January 2014 and December 2019 at a Hong Kong university hospital. Patients were reviewed for up to two months after the last administration of an ICI. The types, onset times and grades of irEDs, including hypothyroidism, hyperthyroidism, adrenal insufficiency and immune-related diabetes mellitus, were recorded. Factors associated with irEDs were identified using multivariate analysis. Result A total of 953 patients (male: 603, 64.0%; median age: 62.0 years) received ICIs during the study period. Of these, 580 patients (60.9%) used ICI-alone, 132 (13.9%) used dual-ICI, 187 (19.6%) used an ICI combined with chemotherapy (chemo+ICI), and 54 (5.70%) used immunotherapy with a targeted agent (targeted+ICI). A significantly higher proportion of patients using targeted+ICI had irEDs and hypothyroidism; in contrast, a higher proportion of patients using dual-ICI had adrenal insufficiency. There was no significant difference in the incidence of irED between the younger (<65 years) and older (>65 years) patients. Using logistic regression, only treatment type was significantly associated with irEDs. Notably, older patients had a higher risk of having immune-related diabetes mellitus. Conclusions This large, real-world cohort demonstrates that combining ICI with targeted therapy has a higher risk of overall irED and hypothyroidism. Immunotherapy is safe and well-tolerated regardless of age, but close monitoring of fasting glucose is needed in older populations.

Working Paper ARTICLE

Photothermal Killing of A549 Cells and Autophagy Induction by Bismuth Selenide Nanoparticles

Yue You, Jinxia Li, Linlin Chen, Mei Wang, Xinghua Dong, Liang Yan, Aiping Zhang, Feng Zhao

Subject: Chemistry And Materials Science, Biomaterials Keywords: bismuth selenide nanoparticles; photothermal killing; apoptosis; autophagy; stress-related signaling pathway

Online: 10 May 2021 (10:52:30 CEST)

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Working Paper ARTICLE

Behavioral, Emotional and Social Apathy in Alcohol-Related Cognitive Disorders

Maud E.G. van Dorst, Yvonne C.M. Rensen, Masud Husain, Roy P.C. Kessels

Subject: Social Sciences, Psychology Keywords: apathy; neuropsychology; Korsakoff’s syndrome; alcohol use disorder; alcohol-related cognitive disorders

Online: 8 April 2021 (10:12:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0282.v1

The Deficit of Multimodal Perception of Congruent and Non-congruent Fearful Expressions in Patients with Schizophrenia: The ERP Study

Galina V Portnova, Aleksandra Maslennikova, Natalia Zakharova, Olga V Martynova

Subject: Social Sciences, Psychology Keywords: EEG; event-related potentials; schizophrenia; fearful expressions; perception; non-congruent sounds

Online: 11 December 2020 (12:58:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0243.v2

Morphological and Molecular Status of Daphne Wolongensis Brickell et Mathew as Genetic Resource for Horticulture

Vojtěch Holubec, Leona Leišová-Svobodová

Subject: Biology And Life Sciences, Horticulture Keywords: Daphne wolongensis; distribution; morphology; relationships; genetics; AFLP; related species; Rehdera section

Online: 16 September 2020 (03:12:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0080.v1

SHERLOCK and DETECTR: CRISPR-Cas Systems as Potential Rapid Diagnostic Tools for Emerging Infectious Diseases and Cancer-Associated Mutations

Mujahed Mustafa, Abdelrafie Makhawi

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: cancer-related viruses; CRISPR-Cas diagnostic tools; DETECTR; infectious disease; SHERLOCKv2

Online: 7 April 2020 (09:43:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201908.0009.v1

Effect of Tea Polyphenol on Serum Hormone, Serum Enzyme Activity and Antioxidant-Related Gene Expression in Chinese Yellow Chicken under Heat Stress

Minxuan Yang, Yinglin Lu, Qizhao Zhu, Peng Gao, Xiaolei Xie, Debing Yu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: tea polyphenol; serum hormone; enzyme activity; immune function, enzyme-related genes

Online: 1 August 2019 (05:18:08 CEST)

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The present study was conducted to evaluate the effects of dietary supplementation of tea polyphenol （TP） on serum hormone, serum enzyme activity, antioxidant-related and immune-related gene expression of laying hens under heat stress. A total of 288 Chinese yellow chicken (186 days old) were randomly distributed among two treatments, each of which included 6 replicates of 24 hens. Dietary treatments were that the basal diet was supplemented with 200 mg / kg tea polyphenol. The study lasted for 7 weeks, including 1 week of adaptation and 6 weeks of the formal test. The content of high-density lipoprotein cholesterol (HDL-C) and total protein (TP) in serum significantly decreased by dietary supplementation with tea polyphenol. Dietary tea polyphenol supplementation improved serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) enzyme activity and decreased serum malondialdehyde (MDA) content in treatments compared to the control. However, supplementation of tea polyphenol did not affect the activity of serum catalase (CAT). The results indicated that long-term feeding of tea polyphenols help to increase the amount of hormones (FSH, E2) associated with reproduction in laying hens and thus improve egg production. It also improved the immune function of laying hens in high temperature environments. Adding tea polyphenols to the diet can significantly increase the serum IgG, IgM content of the laying hens and can upregulate the IgA content. Dietary supplementation of tea polyphenols in the laying hens significantly increased the expression of antioxidant enzyme-related genes (SOD, CAT and GPX1) in the liver. Moreover, the addition of tea polyphenols significantly increased the expression of immune-related genes (Interferon-γ (INF-γ), Interleukin 2 (IL-2) and Interleukin 4 (IL-4)) in the spleen. It is concluded that addition of tea polyphenols has a positive effect on antioxidant activity and immune function of laying hens.

Preprint ARTICLE | doi:10.20944/preprints201810.0565.v1

Aberrant Epigenetic Regulation in Head and Neck Cancer Due to Distinct EZH2 Overexpression and DNA Hypermethylation

Daiki Mochizuki, Yuki Misawa, Hideya Kawasaki, Atsushi Imai, Shiori Endo, Masato Mima, Satoshi Yamada, Takuya Nakagawa, Takeharu Kanazawa, Kiyoshi Misawa

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: EZH2; epigenetic regulation; DZNep; tumor-related genes; head and neck cancer

Online: 24 October 2018 (10:34:10 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints201810.0527.v1

Cross-Modal Priming Effect of Rhythm on Visual Word Recognition and Its Relationships to Music Aptitude and Reading Achievement

Tess S. Fotidzis, Heechun Moon, Jessica R. Steele, Cyrille L. Magne

Subject: Social Sciences, Cognitive Science Keywords: implicit prosody; rhythm sensitivity; event related potentials; reading achievement; musical aptitude

Online: 23 October 2018 (08:30:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0061.v1

Ozlem Koseoglu Ornek, Erdem Sevim

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Work-related stress; occupational stress; coping profile; garment workers; textile workers

Online: 7 February 2018 (10:26:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0906.v1

Age and Density of Mated Females Affect Dispersal Strategies in a Spider Mite

Peng Zhou, Xiong Z. He, Chen Chen, Qiao Wang

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: age-specific reproduction; population density; resource competition; dispersal probability; dispersal distance

Online: 15 April 2024 (05:46:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0344.v1

Analysis of Socio-Emotional Competencies as a Key Dimension for Sustainability in Colombian Elite Athletes

Fabián Humberto Marín-González, Iago Portela-Pino, Juan Pedro Funtes-García, María José Martínez-Patiño

Subject: Social Sciences, Psychology Keywords: High performance; Olympic; Paralympic; gender; age; type of sport; sport modality.

Online: 4 January 2024 (09:35:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0668.v1

Treating Older Children with Clubfoot: Results of a Cross-Sectional Survey of Expert Practitioners

Grace Drury, Timothy R Nunn, Firaol Dandena, Tracey Smythe, Christopher B D Lavy

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Clubfoot; delayed presentation; walking age; neglected; immature; treatment; Ponseti; older child

Online: 9 August 2023 (05:04:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0186.v1

Age Estimation in Human Gait Extraction using A Combination of Multi-Energy Image with Invariant Moment

Nasser Al Musalhi, Erbuğ Çelebi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: age estimation; AFDEI; CNN; human gait; neural networks; GEI; invariant moments

Online: 5 June 2023 (08:12:12 CEST)

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