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Preprint ARTICLE | doi:10.20944/preprints202305.1179.v1

Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

Nadezhda Sabeva, William Castro, Yancy Ferrer-Acosta, Pedro A Ferchmin, Vesna A Eterovic, Demetrio Sierra-Mercado, Naydi Pérez-Rios, Sona Rivas-Tumanyan, Antonio H Martins

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: cembranoids, safety, nonhuman primates, 4R

Online: 17 May 2023 (04:16:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0548.v1

Impact of TSPO Receptor Polymorphism on [18F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders

Franziska J. Vettermann, Stefanie Harris, Julia Schmitt, Marcus Unterrainer, Simon Lindner, Boris-Stephan Rauchmann, Carla Palleis, Endy Weidinger, Leonie Beyer, Florian Eckenweber, Sebastian Schuster, Gloria Biechele, Christian Ferschmann, Vladimir M. Milenkovic, Christian H. Wetzel, Rainer Rupprecht, Daniel Janowitz, Katharina Buerger, Robert Perneczky, Günter U. Höglinger, Johannes Levin, Christian Haass, Joerg C. Tonn, Maximilian Niyazi, Peter Bartenstein, Nathalie L. Albert, Matthias Brendel

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: microglia; neurodegeneration; Alzheimer’s disease; neurooncology; 4R-tauopathies; TSPO-PET

Online: 20 April 2021 (13:28:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202006.0147.v1

Novel Therapeutic Targets and Biomarkers for the Treatment of Progressive Supranuclear Palsy

Imogen Tyer, Alison Hill

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: PSP; Progressive Supranuclear Palsy; 4R-tau; four-repeat tau; MAPT; Microtubule-associated ligand; PET; Positron Emission Tomography

Online: 12 June 2020 (09:41:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0723.v1

Mammalian Animal & Human Retinal Organ Culture as Pre-clinical Model to Evaluate Oxidative Stress and Antioxidant Intraocular Therapeutics

Martina Kropp, Mohit Mohit, Cristina Ioana Leroy-Ciocanea, Laura Schwerm, Nina Harmening, Thais Bascuas, Eline De Clerck, Andreas J. Kreis, Bojan Pajic, Sandra Johnen, Gabriele Thumann

Subject: Medicine And Pharmacology, Ophthalmology Keywords: retina organ culture; neuroretinal degenerative disease; oxidative stress; antioxidant; age-related macular degeneration (AMD); diabetic retinopathy (DR); Scutellarin; PEDF; GM-CSF; 4R

Online: 10 May 2023 (09:42:33 CEST)

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