@article{201910.0276, doi = {10.20944/preprints201910.0276.v1}, url = {https://doi.org/10.20944/preprints201910.0276.v1}, year = 2019, month = {October}, publisher = {Preprints}, author = {Meda R Sandu and Rhona Beynon and Rebecca Richmond and Diana L. Santos Ferreira and Lucy Hackshaw-McGeagh and George Davey Smith and Chris Metcalfe and J Athene Lane and Richard Martin}, title = {Two-step Randomisation: Applying the Results of Small Feasibility Studies of Interventions to Large-scale Mendelian Randomisation Studies to Robustly Infer Causal Effects on Clinical Endpoints}, journal = {Preprints} }