Version 1
: Received: 20 February 2021 / Approved: 22 February 2021 / Online: 22 February 2021 (15:25:02 CET)
How to cite:
Zhao, Y.; Wang, H.; Lin, Z.; Ji, Y.; Chen, Q. Relationship Between D-Dimer / Creatinine Ratio and Coronary Artery Disease Severity in Patients with ST-Segment Elevation Myocardial Infarction. Preprints2021, 2021020485. https://doi.org/10.20944/preprints202102.0485.v1
Zhao, Y.; Wang, H.; Lin, Z.; Ji, Y.; Chen, Q. Relationship Between D-Dimer / Creatinine Ratio and Coronary Artery Disease Severity in Patients with ST-Segment Elevation Myocardial Infarction. Preprints 2021, 2021020485. https://doi.org/10.20944/preprints202102.0485.v1
Zhao, Y.; Wang, H.; Lin, Z.; Ji, Y.; Chen, Q. Relationship Between D-Dimer / Creatinine Ratio and Coronary Artery Disease Severity in Patients with ST-Segment Elevation Myocardial Infarction. Preprints2021, 2021020485. https://doi.org/10.20944/preprints202102.0485.v1
APA Style
Zhao, Y., Wang, H., Lin, Z., Ji, Y., & Chen, Q. (2021). Relationship Between D-Dimer / Creatinine Ratio and Coronary Artery Disease Severity in Patients with ST-Segment Elevation Myocardial Infarction. Preprints. https://doi.org/10.20944/preprints202102.0485.v1
Chicago/Turabian Style
Zhao, Y., Yingying Ji and Qingwei Chen. 2021 "Relationship Between D-Dimer / Creatinine Ratio and Coronary Artery Disease Severity in Patients with ST-Segment Elevation Myocardial Infarction" Preprints. https://doi.org/10.20944/preprints202102.0485.v1
Abstract
Backgroundː Previous studies have shown that both serum creatinine and D-dimer levels were associated with atherosclerotic coronary artery disease (CAD). We aimed to determine whether DCR is associated with coronary Gensini score in patients with ST-elevation myocardial infarction (STEMI). Methodsː 337 STEMI patients with complete D-dimer and creatinine and other necessary information were included in the analysis. According to the values of the DCR, patients were divided into the lower DCR group (DCR ≤ 1.42, n = 173) and the higher DCR group (DFR > 1.42, n = 174), and the differences between the two groups were compared. Multivariate linear and multivariate logistic regression analyses were performed to determine independent predictors of Gensini score. Resultsː High DCR group had higher Gensini score compared with low DCR group (P < 0.05). DCR was positively correlated with Gensini score (r=0.493, P < 0.001). Multiple linear regression analysis showed that Previous MI (r=11.312, P=0.035) and DCR (r=5.129, P<0.001) were independent risk factors associated with Gensini score. Multivariate logistic regression analysis showed that, compared to the group 1, DCR is independent risk factor for Group 2, Group 3, Group 4 (P <0.001). DCR is positively correlated with coronary Gensini score in STEMI patients and can be used as an independent predictor of higher Gensini score. Conclusionsː As a new and useful clinical marker, DCR is positively correlated with coronary Gensini score in STEMI patients and can be used as an independent predictor of higher Gensini score.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
