Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Scoping Review of Selected Studies on Risk Factors Associated with the Malaria Status among Children Under-five Years in Sub-Sahara Africa

Version 1 : Received: 21 January 2021 / Approved: 22 January 2021 / Online: 22 January 2021 (13:08:29 CET)

A peer-reviewed article of this Preprint also exists.

Obasohan, P.E.; Walters, S.J.; Jacques, R.; Khatab, K. A Scoping Review of Selected Studies on Predictor Variables Associated with the Malaria Status among Children under Five Years in Sub-Saharan Africa. Int. J. Environ. Res. Public Health 2021, 18, 2119. Obasohan, P.E.; Walters, S.J.; Jacques, R.; Khatab, K. A Scoping Review of Selected Studies on Predictor Variables Associated with the Malaria Status among Children under Five Years in Sub-Saharan Africa. Int. J. Environ. Res. Public Health 2021, 18, 2119.

Abstract

Background/Purpose: In recent times, Sub-Sahara Africa (SSA) had been rated by the World Health Organization, (WHO), as the most malaria endemic region in the world. Evidence synthesis of the risk factors associated with malaria among children aged under-five in SSA is urgently needed. This would help to inform decisions that policy makers and executors in the region need to make for the effective distribution of scare palliative resources to curb the spread of the illness. This scoping review is aimed to identify studies that have used multivariate classical regression analysis to determine risk factors associated with malaria among children under-five years old in SSA. Methods/Design: The search terms followed PICOTS, (Population, Intervention, Comparator, Outcome, Timing, Setting), and were used in searching through the following databases: PubMed, MEDLINE, Web of Science, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Scopus, and MeasureDHS. The databases were searched for published articles from January 1990 to December 2020. Results: Among the 1154 studies identified, only thirteen (13) studies met the study’s inclusion/exclusion criteria. Narrative syntheses were performed on the selected papers to synchronise the various risk factors identified. Factors ranging from child-related, (age, birth order and use of bed net), parental/household-related, (maternal age and education status, household wealth index) and community-related variables, (community wealth status, free bed net distribution), were some of the identified significant risk factors. Conclusion: It is timely to have a synthesis of risk factors that influence the malaria status of children under-five in SSA. The outcome of the review will increase the knowledge of the epidemiology of morbidity that will form the basis for designing efficient and cost-effective distribution of palliatives and controls of malaria in SSA.

Keywords

Malaria, Fever, Plasmodium falciparum, falciparum vivax, under-five, determinants, risk factors, review

Subject

Medicine and Pharmacology, Tropical Medicine

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