Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Follicular Lymphoma Involving Bilateral Ovaries Following Routine Hysterectomy and Bilateral Salpingo-Oophorectomy: An Incidental Finding

Anoshia Afzal
* ORCID logo ,
Michael Quinton
,
Umar Farooque
,
Sepideh Asadbeigi
,
Bilal Ahmed Khan
,
Shahbaz Khan
Version 1 : Received: 12 December 2020 / Approved: 14 December 2020 / Online: 14 December 2020 (14:51:41 CET)

How to cite: Afzal, A.; Quinton, M.; Farooque, U.; Asadbeigi, S.; Khan, B.A.; Khan, S. Follicular Lymphoma Involving Bilateral Ovaries Following Routine Hysterectomy and Bilateral Salpingo-Oophorectomy: An Incidental Finding. Preprints 2020, 2020120347. https://doi.org/10.20944/preprints202012.0347.v1 Afzal, A.; Quinton, M.; Farooque, U.; Asadbeigi, S.; Khan, B.A.; Khan, S. Follicular Lymphoma Involving Bilateral Ovaries Following Routine Hysterectomy and Bilateral Salpingo-Oophorectomy: An Incidental Finding. Preprints 2020, 2020120347. https://doi.org/10.20944/preprints202012.0347.v1

Abstract

Ovarian lymphoma is an infrequent disease, accounting for less than 1% of all non-Hodgkin lymphoma diagnosis. Symptoms include abnormal vaginal bleeding or discharge, abdominal pain, and urinary obstruction due to the large mass. In our case, a 60-year-old woman, underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy, as she presented with low-grade follicular lymphoma (FL) in both the ovaries, and the left ovary was observed to be enlarged. The tumor is categorized as lymphoma based upon immunohistochemical markers. Computed tomography (CT) scan of the chest, abdomen, and pelvis and bone marrow biopsy are important for the staging of primary lymphoma of the ovary. The first-line chemotherapy regimen includes rituximab, cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (Oncovin), and prednisone (R-CHOP) for rapidly proliferative non-Hodgkin lymphoma (NHL). Lymphomas with slower growth patterns can be treated with Bendamustine-Rituximab and don’t need aggressive R-CHOP treatment.

Keywords

lymphoma; follicular; ovary; chemotherapy

Subject

Medicine and Pharmacology, Immunology and Allergy

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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