Dallas, R.H.; Rains, J.K.; Wilder, K.; Humphrey, W.; Cross, S.J.; Ghafoor, S.; Brazelton de Cardenas, J.N.; Hayden, R.T.; Hijano, D.R. The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin. Pharmaceutics2020, 12, 1163.
Dallas, R.H.; Rains, J.K.; Wilder, K.; Humphrey, W.; Cross, S.J.; Ghafoor, S.; Brazelton de Cardenas, J.N.; Hayden, R.T.; Hijano, D.R. The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin. Pharmaceutics 2020, 12, 1163.
Dallas, R.H.; Rains, J.K.; Wilder, K.; Humphrey, W.; Cross, S.J.; Ghafoor, S.; Brazelton de Cardenas, J.N.; Hayden, R.T.; Hijano, D.R. The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin. Pharmaceutics2020, 12, 1163.
Dallas, R.H.; Rains, J.K.; Wilder, K.; Humphrey, W.; Cross, S.J.; Ghafoor, S.; Brazelton de Cardenas, J.N.; Hayden, R.T.; Hijano, D.R. The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin. Pharmaceutics 2020, 12, 1163.
Abstract
Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen®). We did not observe any adverse events with this method.
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