Obesity and COVID-19 Infection Severity: From Pathophysiology to Clinical Implications

Abdallah Fayssoil; Marie Charlotte De Carne De Carnavalet; Nicolas Mansencal; Frédéric Lofaso; Benjamin Davido

doi:10.20944/preprints202010.0493.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 22 October 2020 / Approved: 23 October 2020 / Online: 23 October 2020 (13:28:04 CEST)

Obesity is a significant public health concern with higher morbidity. Obesity patients are at risk of severe COVID-19 infection and obesity is a higher risk factor for intensive Care Unit admission in COVID-19 infection. Obesity status affects lung volumes, cardiac structure and hemodynamics. Obesity is associated with a low inflammation state, endothelial dysfunction, hyperinsulinaemia and metabolic disorders. The authors review cardio-respiratory pathophysiological aspects involved in obesity and propose clinical management in obese patients infected by COVD-19.

COVID-19; Obesity; BMI; heart; lung; severity

Medicine and Pharmacology, Immunology and Allergy

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Obesity and COVID-19 Infection Severity: From Pathophysiology to Clinical Implications

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