Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Prospects of Nutritional Interventions in the Care of COVID-19 Patients

Version 1 : Received: 20 July 2020 / Approved: 23 July 2020 / Online: 23 July 2020 (07:09:30 CEST)
Version 2 : Received: 24 October 2020 / Approved: 26 October 2020 / Online: 26 October 2020 (11:26:43 CET)

A peer-reviewed article of this Preprint also exists.

Alam, S.; Bhuiyan, F.R.; Emon, T.H.; Hasan, M. Prospects of Nutritional Interventions in the Care of COVID-19 Patients. Heliyon 2021, 7, e06285, doi:10.1016/j.heliyon.2021.e06285. Alam, S.; Bhuiyan, F.R.; Emon, T.H.; Hasan, M. Prospects of Nutritional Interventions in the Care of COVID-19 Patients. Heliyon 2021, 7, e06285, doi:10.1016/j.heliyon.2021.e06285.

Abstract

The novel coronavirus diseases 2019 (COVID-19) has unfolded an unprecedented worldwide public health emergency with disastrous economic consequences. Around 12 million coronavirus cases have already been identified with over half a million deaths. Despite numerous efforts by the government as well as international organizations, these numbers are still increasing with a surprising rate. Although urgent and absolutely necessary, a reliable therapeutic or vaccine is still elusive and this status quo may remain for an uncertain period of time. Taken that into account, boosting up adaptive immunity through nutritional interventions may help subside this epidemic and save many lives. This review focuses on the nexus between a balanced diet and adaptive immunity, particularly, how a poor diet may lead to compromised immunity resulting in susceptibility to viral infections. Additionally, we discuss how nutrients (vitamins, minerals, trace elements) could be used as a tool to modulate immune response and thus impede viral infections. The study also summarized nutritional recommendations to combat COVID-19 in different countries and territories and dietary sources of those key nutrients. Moreover, different nutritional intervention strategies based on different age groups, physiological and medical conditions were also included, and the challenges of nutritional interventions towards the care of COVID-19 patients were also discussed. Since the availability of a drug or vaccine is still uncertain, a balanced diet or nutrient therapy could be used as a robust strategy to combat COVID-19. Thus, we hope this review may help to make an informed decision with regard to diet choice both at individual level as well as clinical settings.

Keywords

Macronutrients; Micronutrients; COVID-19; SARS-CoV-2; Immunity; Complications;

Subject

Medicine and Pharmacology, Dietetics and Nutrition

Comments (1)

Comment 1
Received: 26 October 2020
Commenter: MAHMUDUL HASAN
Commenter's Conflict of Interests: Author
Comment: Dear ConcerN,
We have changed our Figure 1 for a better understanding, and also our previous figure has a minor error. Moreover, we have done a few minor changes in our writing.  

Thanks !
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