Preprint Hypothesis Version 2 Preserved in Portico This version is not peer-reviewed

Amyotrophic Lateral Sclerosis (Als) Disease Clusters in the United States and International Sites: Association With Glacial Lakes and Clay Minerals

Version 1 : Received: 5 July 2020 / Approved: 6 July 2020 / Online: 6 July 2020 (09:11:18 CEST)
Version 2 : Received: 12 December 2020 / Approved: 15 December 2020 / Online: 15 December 2020 (10:21:51 CET)

How to cite: Reddy, K. Amyotrophic Lateral Sclerosis (Als) Disease Clusters in the United States and International Sites: Association With Glacial Lakes and Clay Minerals. Preprints 2020, 2020070100 (doi: 10.20944/preprints202007.0100.v2). Reddy, K. Amyotrophic Lateral Sclerosis (Als) Disease Clusters in the United States and International Sites: Association With Glacial Lakes and Clay Minerals. Preprints 2020, 2020070100 (doi: 10.20944/preprints202007.0100.v2).

Abstract

Amyotrophic lateral sclerosis (ALS) disease clusters are found in several countries worldwide. In the United States, ALS clusters are found in many states, largely within the northern United States. The cause of the increased rates of ALS in these areas remains indefinite. It is reported here that many ALS clusters are associated with sites of current or prior glacial lakes, or regions containing an abundance of silts and clay minerals. The potential significance of these findings in ALS is discussed.

Keywords

amyotrophic lateral sclerosis; ALS; glacial; lake; clay; mineral; United States; Canada; Finland; Vermont; New Hampshire; Maine; Ohio; Wisconsin; Indiana; Minnesota; North Dakota; Montana, Idaho; Washington; Oregon; Colorado; Iowa; Utah

Comments (1)

Comment 1
Received: 15 December 2020
Commenter: Kavitha Reddy
Commenter's Conflict of Interests: Author
Comment: The paper has been expanded to include information from a larger area of the United States and some global data.
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