Version 1
: Received: 9 March 2020 / Approved: 10 March 2020 / Online: 10 March 2020 (03:49:10 CET)
How to cite:
Xu, Y.; Wang, L.; Jia, X.; Feng, Y. 2019-nCoV: A Possible Progenitor for SARS-CoV with Bat Origin?. Preprints2020, 2020030159. https://doi.org/10.20944/preprints202003.0159.v1
Xu, Y.; Wang, L.; Jia, X.; Feng, Y. 2019-nCoV: A Possible Progenitor for SARS-CoV with Bat Origin?. Preprints 2020, 2020030159. https://doi.org/10.20944/preprints202003.0159.v1
Xu, Y.; Wang, L.; Jia, X.; Feng, Y. 2019-nCoV: A Possible Progenitor for SARS-CoV with Bat Origin?. Preprints2020, 2020030159. https://doi.org/10.20944/preprints202003.0159.v1
APA Style
Xu, Y., Wang, L., Jia, X., & Feng, Y. (2020). 2019-nCoV: A Possible Progenitor for SARS-CoV with Bat Origin?. Preprints. https://doi.org/10.20944/preprints202003.0159.v1
Chicago/Turabian Style
Xu, Y., Xu Jia and Youjun Feng. 2020 "2019-nCoV: A Possible Progenitor for SARS-CoV with Bat Origin?" Preprints. https://doi.org/10.20944/preprints202003.0159.v1
Abstract
A novel coronavirus (2019-nCoV) that is initially found to trigger human severe respiratory illness in Wuhan City of China, 2019, has been recognized as a public health emergency of international concern. In the past two months, this deadly agent has caused 77,785 cases with 2,666 deaths via rapid person-to-person transmission and reached at least 25 countries. However, its evolutionary origin is poorly understood. Here we show integrative evidence that 2019-nCoV is a possible progenitor for SARS-CoV with bat origin. Our finding underscores the importance of tracing origin in the efficient monitoring, and effectively preventing the interspecies transmission of such emerging/re-emerging coronaviruses.
Keywords
bat SARS-like CoV; SARS-CoV; 2019-nCoV; phylogeny; spike protein; viral and host fusion
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
