Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Impact of Seaweed-Derived Xanthophyll Carotenoid on Obesity Management: Overview of the Last Decade

Version 1 : Received: 23 February 2020 / Approved: 24 February 2020 / Online: 24 February 2020 (12:26:44 CET)

How to cite: Ojulari, O.V.; Lee, S.G.; Nam, J. Impact of Seaweed-Derived Xanthophyll Carotenoid on Obesity Management: Overview of the Last Decade. Preprints 2020, 2020020349 (doi: 10.20944/preprints202002.0349.v1). Ojulari, O.V.; Lee, S.G.; Nam, J. Impact of Seaweed-Derived Xanthophyll Carotenoid on Obesity Management: Overview of the Last Decade. Preprints 2020, 2020020349 (doi: 10.20944/preprints202002.0349.v1).

Abstract

Present-day lifestyle associated with high calorie-fat intake and accumulation, as well as energy imbalance, has led to the development of obesity and its comorbidities, which have emerged as some of the major health issues globally. To combat the disease, many studies have reported the anti-obesity effects of natural compounds in foods, with some advantages over chemical treatments. Carotenoids, particularly xanthophyll derived from seaweeds, have attracted the attention of researchers due to their notable biological activities, which are associated mainly with their antioxidant properties. Their involvement in oxidative stress modulation, regulation of major transcription factors and enzymes as well as their antagonistic effects on various obesity parameters have been examined in both in-vitro and in-vivo studies. The present review is a collation of published research over the last decade on the anti-oxidant properties of seaweed xanthophyll carotenoids, with a focus on fucoxanthin and astaxanthin and their mechanisms of action in obesity prevention and treatment.

Subject Areas

carotenoids; seaweeds; antioxidants; astaxanthin; fucoxanthin; anti-obesity; oxidative stress

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