Working Paper Article Version 1 This version is not peer-reviewed

Fasciola Hepatica; Demographic, Radiological, Laboratory Findings and Their Role in Acute and Chronic Differentiation

Version 1 : Received: 6 August 2019 / Approved: 7 August 2019 / Online: 7 August 2019 (10:06:02 CEST)

How to cite: Tunc, N. Fasciola Hepatica; Demographic, Radiological, Laboratory Findings and Their Role in Acute and Chronic Differentiation. Preprints 2019, 2019080094 Tunc, N. Fasciola Hepatica; Demographic, Radiological, Laboratory Findings and Their Role in Acute and Chronic Differentiation. Preprints 2019, 2019080094

Abstract

The aims of this study was to investigate demographic, radiological and laboratory features of Fasciola hepatica infection and to determine its effects on acute and chronic differentiation. Materials and Methods: Patients with Fasciola hepatica; demographic data and serological tests, leucocyte, platelet, eucinophil, AST, ALT, bilirubin, amylase were obtained retrospectively. The presence of characteristic findings in radiology and / or Fasciola Hepatica IgG positivity in acute phase and endoscopic retrograde cholangiopancreatography revealed fasciola hepatica extraction as chronic phase. Results: A total of 17 patients 1 male (5.9%) and 16 female (94.1%) were included in the study. The mean age was 46.18 years. Of the cases, 10 (58.8%) were acute, 7 (41.2%) were chronic. In 10 cases (58.8%) eusinophils were higher than 5% and normal in the others. In the USG, 7 (40.9%) were normal, 7 (40.9%) were hypoechoic lesions, and 3 were defined as gallbladder FH. When compared to acute and chronic Fasciola Hepatica; there was no significant difference in laboratory data (p> 0.005). Albumin was 4.6 g / dl, 3.9 g / dl (p = 0.009), and platelet count were 300 x 103/uL (p = 0.004) and 221 x 103/uL respectively. Conclusion; female gender, history of eating watercress, the presence of eosinophili, are finding increased susceptibility to Fasciola hepatica. Laboratory data for acute and chronic differentiation were not helpful but albumin and platelet levels were significantly lower in chronic cases.

Subject Areas

Keywords; acute and chronic fasciola hepatica, eosinophilia, ERCP

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