Preserved in Portico This version is not peer-reviewed
Rediscovering the Ethical Priority of the Most Actionable System of Biomolecules—The Metabolome
: Received: 14 May 2019 / Approved: 15 May 2019 / Online: 15 May 2019 (10:09:48 CEST)
A remarkable feature of US federal investments in human genetics has been the availability of parallel funding for studies examining ethical, legal and social implications (ELSI). This funding has allowed ELSI researchers to develop new strategies to understand genetics, evaluate the benefits of genetic testing, and propose health policy that maximize the promise while minimizing harms. Despite successes, a consequence of this investment is the preoccupation with what is arguably the least actionable system of biomolecules, human DNA. In contrast, the most actionable system of biomolecules, the metabolome, is grossly understudied, despite its often more alarming ELSI.
metabolomics; genomics; ethics
Biology and Life Sciences, Endocrinology and Metabolism
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
* All users must log in before leaving a comment