Preprint Review Version 1 This version is not peer-reviewed

Advances in In-Vivo Imaging of Inflammatory Bowel Disease Mediators

Version 1 : Received: 25 June 2018 / Approved: 25 June 2018 / Online: 25 June 2018 (12:57:48 CEST)

A peer-reviewed article of this Preprint also exists.

Dmochowska, N.; Wardill, H.R.; Hughes, P.A. Advances in Imaging Specific Mediators of Inflammatory Bowel Disease. Int. J. Mol. Sci. 2018, 19, 2471. Dmochowska, N.; Wardill, H.R.; Hughes, P.A. Advances in Imaging Specific Mediators of Inflammatory Bowel Disease. Int. J. Mol. Sci. 2018, 19, 2471.

Journal reference: Int. J. Mol. Sci. 2018, 19, 2471
DOI: 10.3390/ijms19092471

Abstract

Inflammatory Bowel Disease (IBD) is characterized by chronic remitting and relapsing inflammation of the lower gastrointestinal tract. The etiology underlying IBD remains unknown but is thought to involve a hypersensitive immune response to environmental antigen, including the microbiota. Diagnosis and monitoring of disease is heavily reliant on endoscopy, which is invasive and does not provide information regarding specific mediators. This review describes recent developments in imaging of IBD with a focus on PET and SPECT imaging of inflammatory mediators, and how this may be applied to the microbiota.

Subject Areas

Inflammatory Bowel Disease (IBD); colitis; PET; SPECT; microbiota; cytokine; chemokine; inflammation

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