Version 1
: Received: 21 March 2024 / Approved: 21 March 2024 / Online: 21 March 2024 (14:07:15 CET)
How to cite:
Kaur, K.; Al-Khazaleh, A. K.; Bhuyan, D. J.; Li, F.; Li, C. G. A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities. Preprints2024, 2024031292. https://doi.org/10.20944/preprints202403.1292.v1
Kaur, K.; Al-Khazaleh, A. K.; Bhuyan, D. J.; Li, F.; Li, C. G. A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities. Preprints 2024, 2024031292. https://doi.org/10.20944/preprints202403.1292.v1
Kaur, K.; Al-Khazaleh, A. K.; Bhuyan, D. J.; Li, F.; Li, C. G. A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities. Preprints2024, 2024031292. https://doi.org/10.20944/preprints202403.1292.v1
APA Style
Kaur, K., Al-Khazaleh, A. K., Bhuyan, D. J., Li, F., & Li, C. G. (2024). A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities. Preprints. https://doi.org/10.20944/preprints202403.1292.v1
Chicago/Turabian Style
Kaur, K., Feng Li and Chun Guang Li. 2024 "A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities" Preprints. https://doi.org/10.20944/preprints202403.1292.v1
Abstract
Curcumin, as the main active component of Turmeric (Curcuma Longa), has been demonstrated with various bioactivities. However, its potential therapeutic applications are hindered by challenges such as poor solubility and bioavailability, rapid metabolism, and pan-assay interference properties. Recent advancements have aimed to overcome these limitations by developing novel curcumin analogues and modifications. This brief review critically assesses recent studies on synthesising different curcumin analogues, including metal complexes, nano particulates, and other curcumin derivatives, focused on the antioxidant, anti-inflammatory, and anticancer effects of curcumin and its modified analogues. Exploring innovative curcumin derivatives offers promising strategies to address the challenges associated with its bioavailability and efficacy and valuable insights for future research directions.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.