Article
Version 1
Preserved in Portico This version is not peer-reviewed
Comparison of Double Casting Methods for Microfluidic Device Fabrication
Version 1
: Received: 23 February 2024 / Approved: 26 February 2024 / Online: 26 February 2024 (11:42:36 CET)
How to cite: Cherry, B.; Orcutt, A.; Tompkins, N. Comparison of Double Casting Methods for Microfluidic Device Fabrication. Preprints 2024, 2024021437. https://doi.org/10.20944/preprints202402.1437.v1 Cherry, B.; Orcutt, A.; Tompkins, N. Comparison of Double Casting Methods for Microfluidic Device Fabrication. Preprints 2024, 2024021437. https://doi.org/10.20944/preprints202402.1437.v1
Abstract
We compare two methods for creating a microfluidic device from an initial positive master with the same surface relief as the final device. The first method uses urethane or epoxy resin to create an intermediate master for PDMS casting. This method has a very low failure rate but a longer processing time. The second method utilizes PDMS double casting where the intermediate master is passivated PDMS. This method has a higher failure rate but a significantly shorter processing time. Detailed methodology for both methods is included along with a comparison of the strengths and weaknesses of each method. The resin intermediate is a simpler method while PDMS double casting is faster and more scalable. Ultimately it is found that PDMS double casting is preferable in most situations.
Keywords
microfluidics; soft lithography; double casting; PDMS
Subject
Chemistry and Materials Science, Materials Science and Technology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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