Motta, P.B.; Gonçalves, M.L.L.; Gallo, J.M.A.S.; Sobral, A.P.T.; Motta, L.J.; Santos, E.M.; Andrade, D.J.C.; Duran, C.C.G.; Fernandes, K.P.S.; Mesquita-Ferrari, R.A.; Horliana, A.C.R.T.; Bussadori, S.K. Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics—Pilot Study. Healthcare2024, 12, 1123.
Motta, P.B.; Gonçalves, M.L.L.; Gallo, J.M.A.S.; Sobral, A.P.T.; Motta, L.J.; Santos, E.M.; Andrade, D.J.C.; Duran, C.C.G.; Fernandes, K.P.S.; Mesquita-Ferrari, R.A.; Horliana, A.C.R.T.; Bussadori, S.K. Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics—Pilot Study. Healthcare 2024, 12, 1123.
Motta, P.B.; Gonçalves, M.L.L.; Gallo, J.M.A.S.; Sobral, A.P.T.; Motta, L.J.; Santos, E.M.; Andrade, D.J.C.; Duran, C.C.G.; Fernandes, K.P.S.; Mesquita-Ferrari, R.A.; Horliana, A.C.R.T.; Bussadori, S.K. Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics—Pilot Study. Healthcare2024, 12, 1123.
Motta, P.B.; Gonçalves, M.L.L.; Gallo, J.M.A.S.; Sobral, A.P.T.; Motta, L.J.; Santos, E.M.; Andrade, D.J.C.; Duran, C.C.G.; Fernandes, K.P.S.; Mesquita-Ferrari, R.A.; Horliana, A.C.R.T.; Bussadori, S.K. Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics—Pilot Study. Healthcare 2024, 12, 1123.
Abstract
Background: To compare photodynamic therapy 41 and the use of probiotics in reducing halitosis assessed through gas chromatography and microbiome analysis. Methods: Participants aged from 18 to 25 years, showing sulfide (SH2) ≥ 112 ppb on gas chromatography, were selected. They were divided into 4 treatment groups: Group 1 - Tongue Scraping; Group 2- Antimicrobial Photodynamic Therapy (aPDT); Group 3- Probiotics; Group 4- Antimicrobial Photodynamic Therapy (aPDT) and Probiotics. The halimetry process was performed before, immediately after the treatments, 7 days, 14 days and 30 days after the initial collection. The collections for later microbiological analysis were made along with the halimetry, for the microbiome analysis. Results: Treatment with aPDT or probiotics under these experimental conditions was not able to change the bacteria present in the biofilm of the tongue. Conclusions: More research is needed to know the behavior of the oral microbiome in the presence of halitosis and the effectiveness of new treatments.
Medicine and Pharmacology, Dentistry and Oral Surgery
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