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The Feasibility of Semi-continuous and Multifrequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients
Schoutteten, M.K.; Lindeboom, L.; De Cannière, H.; Pieters, Z.; Bruckers, L.; Brys, A.D.H.; van der Heijden, P.; De Moor, B.; Peeters, J.; Van Hoof, C.; Groenendaal, W.; Kooman, J.P.; Vandervoort, P.M. The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients. Sensors2024, 24, 1890.
Schoutteten, M.K.; Lindeboom, L.; De Cannière, H.; Pieters, Z.; Bruckers, L.; Brys, A.D.H.; van der Heijden, P.; De Moor, B.; Peeters, J.; Van Hoof, C.; Groenendaal, W.; Kooman, J.P.; Vandervoort, P.M. The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients. Sensors 2024, 24, 1890.
Schoutteten, M.K.; Lindeboom, L.; De Cannière, H.; Pieters, Z.; Bruckers, L.; Brys, A.D.H.; van der Heijden, P.; De Moor, B.; Peeters, J.; Van Hoof, C.; Groenendaal, W.; Kooman, J.P.; Vandervoort, P.M. The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients. Sensors2024, 24, 1890.
Schoutteten, M.K.; Lindeboom, L.; De Cannière, H.; Pieters, Z.; Bruckers, L.; Brys, A.D.H.; van der Heijden, P.; De Moor, B.; Peeters, J.; Van Hoof, C.; Groenendaal, W.; Kooman, J.P.; Vandervoort, P.M. The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients. Sensors 2024, 24, 1890.
Abstract
Repeated single-point measurements of thoracic bioimpedance at single (low)-frequency are strongly related to fluid changes during hemodialysis. Extension to semi-continuous measurements may provide longitudinal details in the time pattern of the bioimpedance signal, and multifrequency measurements may add in-depth information on the distribution between intra- and extracellular fluid. This study aims to investigate the feasibility of semi-continuous multifrequency thoracic bioimpedance measurements by a wearable device in hemodialysis patients. Therefore, thoracic bioimpedance was recorded semi-continuously (i.e. every ten minutes) at nine frequencies (8 – 160 kHz) in 68 patients during two consecutive hemodialysis sessions, complemented by a single-point measurement at home in-between both sessions. On average, the resistance signals increased during both hemodialysis sessions and decreased during the interdialytic interval. The increase during dialysis was larger at 8 kHz (∆ 32.6 Ω during session 1 and ∆ 10 Ω during session 2) compared to 160 kHz (∆ 29.5 Ω during session 1 and ∆ 5.1 Ω during session 2). Whereas the resistance at 8 kHz showed a linear time pattern, the evolution of the resistance at 160 kHz was significantly different [p < 0.0001]. Measuring bioimpedance semi-continuously and with a multifrequency current is a major step forward in the understanding of fluid dynamics in hemodialysis patients. This study paves the road towards remote fluid monitoring.
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