Review
Version 1
Preserved in Portico This version is not peer-reviewed
The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma
Version 1
: Received: 27 November 2023 / Approved: 28 November 2023 / Online: 29 November 2023 (04:58:57 CET)
A peer-reviewed article of this Preprint also exists.
Oberoi, M.; Noor, M.S.; Abdelfatah, E. The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma. Cancers 2024, 16, 288. Oberoi, M.; Noor, M.S.; Abdelfatah, E. The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma. Cancers 2024, 16, 288.
Abstract
Gastroesophageal (GE) junction adenocarcinoma is an aggressive malignancy of growing incidence and is associated with public health issues such as obesity and GERD. Management has evolved over the last 2 decades to incorporate a multidisciplinary approach including endoscopic intervention, and neoadjuvant chemotherapy/ chemoradiation and minimally invasive or more limited surgical approaches. Surgical approaches include esophagectomy, total gastrectomy, and more recently proximal gastrectomy. This review analyzes the evidence for and applicability of these varied approaches in management as well areas of continued controversy and investigation.
Keywords
GE junction cancer; Esophagogastric cancer; Gastroesophageal cancer; Esophageal cancer; Gastric cancer; Esophagectomy; Gastrectomy; Proximal gastrectomy
Subject
Medicine and Pharmacology, Surgery
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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