Sircu, V.; Colesnic, S.-I.; Covantsev, S.; Corlateanu, O.; Sukhotko, A.; Popovici, C.; Corlateanu, A. The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP. Clocks & Sleep2023, 5, 333-349.
Sircu, V.; Colesnic, S.-I.; Covantsev, S.; Corlateanu, O.; Sukhotko, A.; Popovici, C.; Corlateanu, A. The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP. Clocks & Sleep 2023, 5, 333-349.
Sircu, V.; Colesnic, S.-I.; Covantsev, S.; Corlateanu, O.; Sukhotko, A.; Popovici, C.; Corlateanu, A. The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP. Clocks & Sleep2023, 5, 333-349.
Sircu, V.; Colesnic, S.-I.; Covantsev, S.; Corlateanu, O.; Sukhotko, A.; Popovici, C.; Corlateanu, A. The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP. Clocks & Sleep 2023, 5, 333-349.
Abstract
Repeated desaturation of oxyhemoglobin, micro-arousals, which are typical in obstructive sleep apnea syndrome (OSAS), have negative effects on the health of patients, leading to a wide range of complications such as cardiovascular (arterial hypertension, pulmonary hypertension, chronic heart failure, arrhythmias, myocardial infarction) cerebrovascular (strokes), metabolic (insulin resistance, obesity, diabetes mellitus, metabolic syndrome), gastrointestinal (non-alcoholic liver disease), urinary (chronic renal failure), neuropsychiatric complications and a wide range of malignancies. This in turn has a multilateral effect on familial, occupational and social life, as well as increasing the risk of road traffic accidents or accidents at workplace. Awareness, timely screening and prevention of complications play an important role in the diagnosis and treatment of comorbid conditions. This review focuses on comorbidities in OSAS and the effect of CPAP therapy on their prognosis.
Medicine and Pharmacology, Pulmonary and Respiratory Medicine
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