GO:0005515	protein binding	1476
GO:0043167	ion binding	757
GO:0000166	nucleotide binding	382
GO:0016787	hydrolase activity	347
GO:0003676	nucleic acid binding	312
GO:0016740	transferase activity	239
GO:0005215	transporter activity	188
GO:0005198	structural molecule activity	181
GO:0030234	enzyme regulator activity	162
GO:0008289	lipid binding	126
GO:0060089	molecular transducer activity	77
GO:0009055	electron transfer activity	44
GO:0060090	molecular adaptor activity	36
GO:0003682	chromatin binding	31
GO:0030246	carbohydrate binding	26
GO:0016209	antioxidant activity	19
GO:0045182	translation regulator activity	6
GO:0031386	protein tag	2
GO:0019825	oxygen binding	1
