PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis
Version 1
: Received: 21 November 2016 / Approved: 22 November 2016 / Online: 22 November 2016 (13:00:45 CET)
How to cite:
Lauer, K.; Wahl, A.; Geilenkeuser, M. A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis. Preprints2016, 2016110114. https://doi.org/10.20944/preprints201611.0114.v1
Lauer, K.; Wahl, A.; Geilenkeuser, M. A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis. Preprints 2016, 2016110114. https://doi.org/10.20944/preprints201611.0114.v1
Lauer, K.; Wahl, A.; Geilenkeuser, M. A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis. Preprints2016, 2016110114. https://doi.org/10.20944/preprints201611.0114.v1
APA Style
Lauer, K., Wahl, A., & Geilenkeuser, M. (2016). A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis. Preprints. https://doi.org/10.20944/preprints201611.0114.v1
Chicago/Turabian Style
Lauer, K., Annette Wahl and Marcel Geilenkeuser. 2016 "A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis" Preprints. https://doi.org/10.20944/preprints201611.0114.v1
Abstract
An increased risk of multiple sclerosis (MS) had been found when individuals had consumed large amounts of processed meat and sausages at young age (Lauer, 2014). Furthermore it was found in many studies that MS patients had acquired a number of common childhood infections at higher ages than controls. Therefore, MS patients from an epidemiological long-term investigation in Germany and different hospital controls, were evaluated for a statistical interaction of these two factors. 324 MS patients and 242 hospital controls were inquired. The study focussed on age 0 - 16. Subjects were tested for additive interaction by multiple linear regression analysis (Knol et al., 2007). There was an additive interaction of the age at any common childhood infection with the consumption of scalded sausages (regression estimate = 0.1370; standard error = 0.0603; p = 0.0239). In contrast, no such interaction could be shown for: animal fats; smoked meat (e.g. ham and bacon); and cold - smoked German salami. Thus there was a synergy of the intake of scalded sausages (e.g. frankfurters, bolognas, etc.) and age at common childhood infections, for the later risk of MS.
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.