Preprint Article Version 1 NOT YET PEER-REVIEWED

Potential Application of Modified α-Mangostin Xanthones from Garcinia mangostana as Antibacterial Agents in Food Packaging

  1. Asthagiri Herbal Research Foundation, 162A, Perungudi Industrial Estate, Perungudi, Chennai 600096, India
  2. Institute of Sciences of Food Productions, CNR-ISPA, Lecce, Italy
  3. Department of Biology, Chemistry and Environmental Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates
Version 1 : Received: 1 August 2016 / Approved: 2 August 2016 / Online: 2 August 2016 (09:02:09 CEST)

How to cite: Narasimhan, S.; Maheshwaran, S.; Poltronieri, P.; Abu-Yousef, I.; Majdalawieh, A.; Rethavathi, J.; Das, P. Potential Application of Modified α-Mangostin Xanthones from Garcinia mangostana as Antibacterial Agents in Food Packaging. Preprints 2016, 2016080013 (doi: 10.20944/preprints201608.0013.v1). Narasimhan, S.; Maheshwaran, S.; Poltronieri, P.; Abu-Yousef, I.; Majdalawieh, A.; Rethavathi, J.; Das, P. Potential Application of Modified α-Mangostin Xanthones from Garcinia mangostana as Antibacterial Agents in Food Packaging. Preprints 2016, 2016080013 (doi: 10.20944/preprints201608.0013.v1).

Abstract

The microbial contamination in food packaging have been a major concern that paved the way for the search for natural based new anti-microbial agents, such as modified α-mangostin. In the present work, twelve synthetic analogs were obtained via semi-synthetic modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C), alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic analogs showed higher therapeutic value than the parent molecule. The anti-microbial studies proved that I E showed higher antibacterial activity whereas I I showed most significant antifungal activity. Due to their microbial properties, modified α-mangostin can be utilized as active anti-microbial agents in food packaging.

Subject Areas

α-mangostin; antibacterial; antifungal; food packaging; semi-synthetic modification

Readers' Comments and Ratings (0)

Discuss and rate this article
Views 203
Downloads 215
Comments 0
Metrics 0
Discuss and rate this article

×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.