Narasimhan, S.; Maheshwaran, S.; Poltronieri, P.; Abu-Yousef, I.A.; Majdalawieh, A.F.; Rethavathi, J.; Das, P.E. Potential Application of Modified α-Mangostin Xanthones from Garcinia mangostana as Antibacterial Agents in Food Packaging. Preprints2016, 2016080013. https://doi.org/10.20944/preprints201608.0013.v1
APA Style
Narasimhan, S., Maheshwaran, S., Poltronieri, P., Abu-Yousef, I.A., Majdalawieh, A.F., Rethavathi, J., & Das, P.E. (2016). Potential Application of Modified <em>α</em>-Mangostin Xanthones from <em>Garcinia mangostana</em> as Antibacterial Agents in Food Packaging. Preprints. https://doi.org/10.20944/preprints201608.0013.v1
Chicago/Turabian Style
Narasimhan, S., Janarthanam Rethavathi and Prince Edwin Das. 2016 "Potential Application of Modified <em>α</em>-Mangostin Xanthones from <em>Garcinia mangostana</em> as Antibacterial Agents in Food Packaging" Preprints. https://doi.org/10.20944/preprints201608.0013.v1
Abstract
The microbial contamination in food packaging have been a major concern that paved the way for the search for natural based new anti-microbial agents, such as modified α-mangostin. In the present work, twelve synthetic analogs were obtained via semi-synthetic modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C), alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic analogs showed higher therapeutic value than the parent molecule. The anti-microbial studies proved that I E showed higher antibacterial activity whereas I I showed most significant antifungal activity. Due to their microbial properties, modified α-mangostin can be utilized as active anti-microbial agents in food packaging.
Chemistry and Materials Science, Medicinal Chemistry
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